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Antimicrobial Use Guidelines (AMUG) version 21 - UW Health

Antimicrobial Use Guidelines (AMUG) version 21 - UW Health

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Table 2 Suggested pyrazinamide doses, using whole tablets, for adults weighing 40-90 kilogramsWeight (kg)*40-55 56-75 76-90Daily, mg (mg/kg) 1,000 (18.2 – 25) 1,500 (20 – 26.8) 2,000 † (22.2 – 26.3)Three times weekly, mg (mg/kg) 1,500 (27.3 – 37.5) 2,500 (33.3 – 44.6) 3,000 † (33.3 – 39.5)Twice weekly, mg (mg/kg) 2,000 (36.4 – 50) 3,000 (40 – 53.6) 4,000 † (44.4 – 52.6)*Based on estimated lean body weight.Maximum dose regardless of weight.Table 3 Suggested ethambutol doses, using whole tablets, for adults weighing 40-90 kilogramsWeight (kg)*40-55 56-75 76-90Daily, mg (mg/kg) 800 (14.5 – 20) 1,200 (16 – <strong>21</strong>.4) 1,600 † (17.8 – <strong>21</strong>.1)Three times weekly, mg (mg/kg) 1,200 (<strong>21</strong>.8 – 30) 2,000 (26.7 – 35.7) 2,400 † (26.7 – 31.6)Twice weekly, mg (mg/kg) 2,000 (36.4 – 50) 2,800 (37.3 – 50) 4,000 † (44.4 – 52.6)*Based on estimated lean body weight.Maximum dose regardless of weight.

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