VIRAL INFECTION - Faculty of Medicine
VIRAL INFECTION - Faculty of Medicine VIRAL INFECTION - Faculty of Medicine
Human papilloma virus (HPV)• Most common causes of sexuallytransmitted infection (STI) in the world• HPV types cause benign skin wart,anogenital warts, anogenital cancerHuman papilloma virus (HPV)• Transmitted by skin-to-skin contactduring sexual intercourse• Treated by electrocautery, lasertreatment• Histology : koilocytosis of infected cells• Warts: proliferative squamous epitheliumproducing nodules or flat lesionsHuman papilloma virus (HPV)Skin warts• Skin warts- HPV types 1,2- common warts (verruca vulgaris):hands, trunk, extremities- plantar warts: plantar- no associated with cancerHuman papilloma virus (HPV)Anogenital warts(condylomata acuminata)• Anogenital warts (condyloma acuminatum)- HPV types 6,11- warts at penis, vulva, vagina, anus- no associated with cancer• Anogenital cancer (squamous cell carcinoma)- HPV types 16,18,31,45- cause of cancer of anus, vulva, cervixand penis
Squamous cell carcinoma of cervixPathogenesistransmitted primarily through direct skin contactwith an infected individualvirus infects epidermis causing hyperplasia,hypertrophy and central degeneration of theepidermisepidermis has molluscum bodies contain largenumbers of maturing virionsKoilocytosis of infected cellsMolluscum contagiosumMolluscum virusintracytoplasmic inclusion bodies(molluscum bodies)• Cause of molluscum contagiosum•Self-limited viral disease of skin• Transmitted by skin or sexual contact• Gross: raised, umbilicated, cutaneousnodules at skin (most perineum)• Histology: intracytoplasmic inclusionbodies (molluscum bodies)
- Page 3: Influenza Antigenic Changes• Anti
- Page 10 and 11: Measles virus• Clinical:- conjunc
- Page 12 and 13: Recurrent herpes simplex infectionH
- Page 14 and 15: Herpes zoster (shingles)Varicella (
- Page 16 and 17: Cytomegalovirus (CMV)• Produce a
- Page 18 and 19: Human Immunodeficiency Virus(HIV)
- Page 22 and 23: Intracytoplasmic inclusion bodies(m
Human papilloma virus (HPV)• Most common causes <strong>of</strong> sexuallytransmitted infection (STI) in the world• HPV types cause benign skin wart,anogenital warts, anogenital cancerHuman papilloma virus (HPV)• Transmitted by skin-to-skin contactduring sexual intercourse• Treated by electrocautery, lasertreatment• Histology : koilocytosis <strong>of</strong> infected cells• Warts: proliferative squamous epitheliumproducing nodules or flat lesionsHuman papilloma virus (HPV)Skin warts• Skin warts- HPV types 1,2- common warts (verruca vulgaris):hands, trunk, extremities- plantar warts: plantar- no associated with cancerHuman papilloma virus (HPV)Anogenital warts(condylomata acuminata)• Anogenital warts (condyloma acuminatum)- HPV types 6,11- warts at penis, vulva, vagina, anus- no associated with cancer• Anogenital cancer (squamous cell carcinoma)- HPV types 16,18,31,45- cause <strong>of</strong> cancer <strong>of</strong> anus, vulva, cervixand penis
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