Prevention of CKD in patients with renal stone disease - โรงพยาบาล ...

Natural History of DNCardiovascular DeathsIncipient nephropathy(10 – 40%)•Microalbuminuria•Hypertension•Poorglycemic controlOvert nephropathy(5 – 8%)0 2 5 5 – 15 10 – 20 20 – 30Time (years)Onset ofDM?Onset ofProteinuriaRisingCreatinineEnd-StageRenalFailureFunctional changes(15 – 45%)•Hyperfiltration•EnlargedkidneysStructural changes(2 – 5%)•GMthickening•Mesangialexpansion•± Microvascular changes