MANAGEMENT OF BARRETT'S ESOPHAGUS - CME Conferences

MANAGEMENT OF BARRETT'S ESOPHAGUS - CME Conferences MANAGEMENT OF BARRETT'S ESOPHAGUS - CME Conferences

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3 rd Annual Essentials in Primary CareSummer Conference: Session 1Thursday, July 26, 2012INCIDENCE OF ESOPHAGEALCANCER IN U.S.WHITE MALESCase per 100,000 person-years5432101970 1975 1980 1985 1990 1995AdenoSquamous(Devesa S, et at: Cancer 83:2049,1998)BARRETT’S ESOPHAGUS RISK FACTORS• Caucasian male• Older age: >40 yrs; >50 yrs ?• Duration of GERD: >5 yrs; >10 yrs ?• Visceral fat: waist size ?• Family history• H. pylori freeDonald Castell, MDManagement of Barrett’s Esophagus

3 rd Annual Essentials in Primary CareSummer Conference: Session 1Thursday, July 26, 2012GASTRIC ACID CONTROL IN BEIs symptom relief a reliable index?DECREASED ACID SENSITIVITY IN BARRETT’SPositive Bernstein (%)100508642Time to Sx (min)0RE BE RE BE(Johnson D, et al: J Clin Gastroenterol 9:23, 1987)Donald Castell, MDManagement of Barrett’s Esophagus

3 rd Annual Essentials in Primary CareSummer Conference: Session 1Thursday, July 26, 2012GASTRIC ACID CONTROL IN BEIs symptom relief a reliable index?DECREASED ACID SENSITIVITY IN BARRETT’SPositive Bernstein (%)100508642Time to Sx (min)0RE BE RE BE(Johnson D, et al: J Clin Gastroenterol 9:23, 1987)Donald Castell, MDManagement of Barrett’s Esophagus

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