12.07.2015 Views

UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME

UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME

UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME

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Tegaserod• Adverse events reported significantly more oftenwith tegaserod than with placebo were headache(15% vs. 12%) and diarrhea (9% vs. 4%)• A pooled analysis of data from 29 placebo‐controlledtrials identified 13 ischemic events among 11,614patients treated with tegaserod compared with asingle case among 7,013 placebo‐treated patients.The rate of ischemic events was 0.11% in thetegaserod patients versus 0.01% in the placebogroup• Suspended in US market since 2007

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