UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME
UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME UPDATES ON MANAGEMENT OF IRRITABLE BOWEL SYNDROME
Who needs colonoscopy ?• ACG recommendation :Colonoscopic imaging should be performed in IBS patientswith alarm features to rule out organic diseases and inthose over the age of 50 years for the purpose of colorectalcancer screening.
Emerging specific Investigations• Celiac disease Tissue transglutaminase antibody (TTGA) Capsule endoscopy• Lactose intolerance lactose breath test• Small intestine bacterial overgrowth lactose breath test• Visceral hypersensitivity faecal serine protease activity• Microscopic colitis Random colonic biopsy
- Page 1 and 2: UPDATES ON MANAGEMENT OFIRRITABLE B
- Page 3 and 4: Prevalence• Common GI condition
- Page 5 and 6: Prevalence in HK• Hong Kong 1000
- Page 7 and 8: Impact• Direct cost Prescription
- Page 9 and 10: Clinical manifestations• Othersbe
- Page 13 and 14: DIAGNOSIS
- Page 15 and 16: Manning criteria• > 3 of the foll
- Page 17 and 18: Symptom‐based diagnosticcriteriaL
- Page 19 and 20: How alarming ?SensitivitySpecificit
- Page 21: Diagnosis• Consensus statement is
- Page 25 and 26: PATHOPHYSIOLOGY
- Page 27 and 28: Genetic predisposition• Similar s
- Page 29 and 30: Visceral Hypersensitivity andBrain
- Page 31 and 32: Small Intestine BacterialOvergrowth
- Page 33 and 34: Psychological Dysfunction• Not et
- Page 35 and 36: General PrincipleNon pharmacologica
- Page 37: Compare components of placebo effec
- Page 40 and 41: Outcomes at six week follow-upKaptc
- Page 42 and 43: Patient Education• Explain about
- Page 44: Psychosocial Therapies• Interpers
- Page 48 and 49: Pharmacological treatment• IBS wi
- Page 51 and 52: NNT=5(95% CI 4‐9 )
- Page 53 and 54: Anti‐depressantsSSRI• Less publ
- Page 55 and 56: Psychosocial TherapiesCBT• Cognit
- Page 57 and 58: IBS WITH DIARRHEA
- Page 59 and 60: Alosetron• 1 st IBS specific medi
- Page 61 and 62: Summary of Treatment forIBS‐assoc
- Page 63 and 64: FiberNNT: 11(95%CI ,5‐100)
- Page 65: Tegaserod• Only 5HT4 Receptor ago
- Page 69 and 70: Lubiprostone• Selective C‐2 chl
- Page 71 and 72: Summary of Treatment forIBS‐assoc
Who needs colonoscopy ?• ACG recommendation :Colonoscopic imaging should be performed in IBS patientswith alarm features to rule out organic diseases and inthose over the age of 50 years for the purpose of colorectalcancer screening.
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