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sini - UKM Medical Centre - Universiti Kebangsaan Malaysia

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FF1113CELLULAR BIOMOLECULESThe aim of this module is to describe to the students the structure and function ofbiomolecules and their role in cellular structure and function. The module will emphasiseand relate protein structure to their functions. Enzymes will be introduced as importantbiocatalysts and as a tool in diagnosis. The synthesis of proteins and its regulationwill also be discussed. In addition, the module will discuss the structure of DNA inrelation to its function in inheritance and expression of genetic material, differentiatebetween eukaryotic and prokaryotic processes and explain how these differences can beexploited therapeutically. Several structural abnormalities in biomolecules leading todiseases will also be illustrated. Students will also perform some biochemical tests andbe able to relate this to the structure and function of biomolecules.References1. Agur, A.M.R., Dalley, A.F. & Moore, K.L. 2009. Clinically Oriented Anatomy.6th Edition. USA:Lippincott Williams and Wilkins.2. Lieberman, M & Marks, A. 2008. Basic <strong>Medical</strong> Biochemistry: A ClinicalApproach. 2nd Edition. USA: Lippincott Williams & Wilkins Publications.3. Snell, R.S. 2003. Clinical Anatomy for <strong>Medical</strong> Students. 7th Edition. USA:Lippincott William and Wilkins.4. Baynes, J. & Dominiczak, M.H. 2009. <strong>Medical</strong> Biochemistry. 3rd Edition. UK:Elsevier Health Sciences.5. Murray, R.K., Granner, D.K., Mayes, P.A. & Rodwell, V.W. 2007. Harper’sBiochemistry. USA:Appleton & Lange.FF1213TISSUES OF BODYThe previous module exposes students to the structure and functions of cellularcomponents which is essential to understand the structure and functions of the bodytissues. Knowledge in this area will enable students to understand the disease processes,and hence the management involved, which is central to medicine. This moduleinvolves input from various disciplines such as Anatomy, Biochemistry, Physiology andPathology and aims to enable students to:• describe the living body as a cellular system• classify basic tissues and explain their embryological derivation.• explain cellular basis of diseases.

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