Process - Physician - Fraser Health Authority

Olanzapine (Zyprexa)Tablets, wafers: 2.5, 5, 7.5, 10, 15, 20 mg. Intramuscular Injection: 10 mg vial- wafers good for post surgical GI problems- good for bipolar mania, depression and maintenance- problems with weight gain.- Agitation/insomnia 2.5 – 5 mg- Depression 5 – 10mg good alone or with SSRI (Prozac most commonly)- Borderline Personality disordero Good for anxiety, paranoia, impulsivity but not depressiono 5mg / dayRisperidone (Risperdoal)Tablets: 0.25, 0.5, 1, 2, 3, and 4 mg. Oral solution: 1 mg/mL. Orally disintegrating tablets: 0.5,1, 2, 3, and 4 mg. Powder for injection: 12.5, 25, 37.5, and 50 mg.- not as sedating as Olanzapine or Clozapine- good with OCD, Tourettes, schizophrenia, bipolar mania- Depression – used with SSRI may give up to 2.5 x response- side effects:o increased prolactin causing sore breasts, lactationo akithesia (restlessness)Quetiapine (Seroquel)Tablets: 25, 50, 100, 200, 300, and 400 mg- new long acting tab, not much difference but regular may be better for sleep, agitation- not as strong an antipsychotic as above- good for anxiety or insomnia ( 12.5 – 100 mg/hs) – very effective without rebound oraddictive potential- long acting version good as anti-depressant alone- may help with cocaine withdrawlZiprasidone (Zeldox)capsules of 20 mg, 40 mg, 60 mg and 80 mg. The injectable form is available in vialscontaining 20 mg of lyophilized ziprasidone that must be reconstituted with 1.2 ml of sterilewater before injection.- not as sedating, less weight gain- QT prolongation therefore do baseline ECG and watch when patient on cardiac drugs.Safe if normal ECG.Paliperidone (Invega)Tablets: 1.5 mg, 3 mg, 6 mg, and 9 mg- active metabolite of risperidone