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Alternative pathogen survival mechanisms- predator cytotoxicity• Gram negative organisms produce vesicles ontheir surfaces• Vesicles from E. coli O157:H7 contain shiga toxins• When engulfed by Acanthamoeba the toxin killsthe organism• A possible survival mechanism in soil?

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Alternative pathogen survival mechanisms- predator cytotoxicity• Gram negative organisms produce vesicles ontheir surfaces• Vesicles from E. coli O157:H7 contain shiga toxins• When engulfed by Acanthamoeba the toxin killsthe organism• A possible survival mechanism in soil?

E. coli O157:H7 producing vesicles containingshiga toxinsVesiclesKolling & Matthews, 1999

Page 4 and 5: Bovine GI tractpH (6.0-7.0)pH (2.0-
Page 7: Pathogen survival in the GI tract
Page 11 and 12: Survival in the abomasum• Cells e
Page 13 and 14: Acid adaptation in the live animal
Page 15 and 16: Stresses which occur in foods & in
Page 17 and 18: Leyer and Johnson, 1992The influenc
Page 19 and 20: Pathogen replication in Acanthamoeb
Page 21: Pathogen survival in protozoa• En