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Acid adaptation and resistance infoods & humans• During food processing enteric pathogens maybecome acid adapted• This ensures survival in the human stomach• Stresses induced in foods are also found inhumans
Stresses which occur in foods & in humansFoods/process Stress Human bodyMayonnaise, fermented Acid Stomach/small intestinefoods pepperoni, salami colon/phagosomesCooking/processing Heat Temperature upshiftintracellularenvironmentFish, brines, marinades Osmolarity Stomach(salt solutions)Sous vide - VP Anaerobiosis Phagosomesof meatSheridan & McDowell, 1998
Page 4 and 5: Bovine GI tractpH (6.0-7.0)pH (2.0-
Page 7: Pathogen survival in the GI tract
Page 11 and 12: Survival in the abomasum• Cells e
Page 13: Acid adaptation in the live animal
Page 17 and 18: Leyer and Johnson, 1992The influenc
Page 19 and 20: Pathogen replication in Acanthamoeb
Page 21 and 22: Pathogen survival in protozoa• En
Page 23 and 24: E. coli O157:H7 producing vesicles

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