Gary Benson - Haematology Association of Ireland

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Clinical Manifestations• May be acute or insidious onset• Mucocutaneous Bleeding*petechiae, purpura, ecchymosis*epistaxis, gum bleeding*menorrhagia*GI bleed, CNS bleed = RARE
Page 1 and 2: Overview of ITPDr Gary BensonDirect
Page 3: Statistics of ITP• Incidence of 2
Page 9 and 10: Aetiology of ITP : Adults• ?? Aut
Page 11 and 12: Diagnosis (of Exclusion)• Rule ou
Page 13 and 14: Anti-Platelet Antibody Testing• N
Page 15 and 16: Management of ITP in Adults• Emer
Page 17 and 18: “Safe” Platelet Counts• “mo
Page 19 and 20: Initial Therapy• Prednisolone 1 m
Page 21 and 22: Treatment Side-Effects•Steroids*b
Page 23 and 24: Response Post-Splenectomy• Usuall
Page 25 and 26: Chronic Refractory ITP• Persisten
Page 27 and 28: ITP and Health-Related QOLMean SF-3
Page 29 and 30: Mechanism-Based Approaches toTreatm
Page 31 and 32: Romiplostim Trials - Platelet Count
Page 33 and 34: Mean Platelet Count andMean (SE) Pl
Page 35 and 36: Eltrombopag Enhances Platelet Count
Page 37 and 38: Initial Treatment of Adult ITPPlate
Page 39: Wrapping it up…• ITP is often a

Gary Benson - Haematology Association of Ireland

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