Gary Benson - Haematology Association of Ireland

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Idiopathic (Immune)Thrombocytopenic Purpura• Thrombocytopenia in the absence of otherblood cell abnormalities (normal RBC &WBC, normal blood film)• No clinically apparent conditions ormedications that can account forthrombocytopenia
Statistics of ITP• Incidence of 22 /million/year in one study• Prevalence greater as often chronic*Segal et al 100 /million/year*age-adjusted prevalence 9.5/100,000*1.9 :1 females / males
Page 1: Overview of ITPDr Gary BensonDirect
Page 8 and 9: Aetiology of ITP : Children• Mate
Page 10 and 11: Diagnosis (of Exclusion)• Rule ou
Page 12 and 13: To Marrow or Not to Marrow?• Bone
Page 14 and 15: Management of ITP in Adults• Emer
Page 16 and 17: General Principles of Therapy• Ma
Page 18 and 19: When Planning Therapy…• Tailor
Page 20 and 21: Second-Line Therapy• IV Immune Gl
Page 22 and 23: Splenectomy• Usually reserved for
Page 24 and 25: Data from Fabris, F, et al. Br J Ha
Page 26 and 27: When all else fails…• Steroids
Page 28 and 29: Pathophysiology of ITPOAPOAutoantib
Page 30 and 31: Thrombopoietin Levels in ITP25025Pl
Page 32 and 33: Durable Responses in RomiplostimTri
Page 34 and 35: Eltrombopag and Median PlateletCoun
Page 36 and 37: Emergency Treatment of Adult ITP•
Page 38 and 39: Treatment of Patients FailingPlatel

Gary Benson - Haematology Association of Ireland

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