Gary Benson - Haematology Association of Ireland
Gary Benson - Haematology Association of Ireland
Gary Benson - Haematology Association of Ireland
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Mechanism-Based Approaches toTreatment• Inhibit phagocyte-mediated clearance <strong>of</strong> Ab-coated platelets– Steroids– Splenectomy– Anti-D– IVIG• Decrease antibody production– Rituximab– Steroids– Azathioprine and other immunosuppressants (eg, cyclophosphamide,cyclosporine, mycophenolate m<strong>of</strong>etil)• Impair T and B cell interactions– Steroids– Rituximab– Other immunosuppressants• Enhance platelet production– Thrombopoietic agents– Interleukin 11
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