FA 5 Progress Report WV-INBRE - Joan C. Edwards School of ...

Program Director/Principal Investigator (Last, First, Middle): Rankin, Gary O 34CENTER FOR NATURAL PRODUCTS RESEARCH (0040)TYPE:%IDeA $:Infrastructure4.000% IDeA $: 148,500INVESTIGATOR, DEGREERankin, Gary O PHDChen, Yi C PHDCrick, Darrell PHDHankins, Gerald PHDHarris, Rob PHDHuggins, Luke PHDTroyer, Timothy PHDValentovic, Monica PHDDEPARTMENTPharmacology,Physiology & ToxBiologyChemistryBiologyBiologyBiologyChemistryPharmacology,Physiology & ToxNON-HOST INSTITUTION: STATE,COUNTRYAlderson-Broaddus College, Wv UsaConcord University, Wv UsaWest Virginia State University, Wv UsaWest Virginia State University, Wv UsaWest Virginia Wesleyan College, WvUsaWest Virginia Wesleyan College, WvUsaTotal # human subjects expected for entire study: 0Total # human subjects enrolled to date: 0SUBPROJECT DESCRIPTIONFor several years, investigators within the WV-INBRE network has expressed an interest in natural productsresearch and a number of Faculty Research Development Awards were made to start drug discoveryprojects related to natural sources. The External Advisory Committee recomended that WV-INBRE looktoward organizing researchers around the state to promote synergistic interactions for the discovery of newchemotherapeutic agents, a common theme among early projects and part of the research emphasis ofWV-INBRE, from natural products. To that end, WV-INBRE has sought and received approval from NIH tomove forward to develop the Center for Natural Products Research. Dr. Rankin will serve as the initialDirector for the Center as it is organized, and EAC member and COBRE PI, Dr. Stephen Cutler, Chair,Department of Medicinal Chemistry, University of Mississippi, will serve as consultant to the developingcenter which is currently being organized.SUBPROJECT PROGRESSResearchers from Alderson-Broaddus College, Concord University, West Virginia State University,West Virginia Wesleyan College, Marshall University and West Virginia University have expressedan interest in being part of the Center. Equipment has been purchased for researchers atAlderson-Broaddus College, Concord University and West Virginia State University to facilitatenatural products research projects at these PUIs. A full organizational meeting of interestedinvestigators will be held in late March or early April and projects selected for funding in Y12.PROTECTION AGAINST RESEARCH RISKSN 1. Will human subjects be involved next year?N 2. Will vertebrate animals be used next year?N 3. Will recombinant DNA experiment(s) be conducted next year?N 4. Are there potential hazards to laboratory workers (carcinogens, pathogens, ionizing radiation, etc.)involved in the proposed research for next year? If yes, identify:N 5. Will any of the research-risk categories,not involved next year, be involved future years? If yes, identify:PHS 2590 (Rev. 06/09)Continuation Format Page