FA 5 Progress Report WV-INBRE - Joan C. Edwards School of ...

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Program Director/Principal Investigator (Last, First, Middle): Rankin, Gary O 24WV-INBRE: WVU & MARSHALL U: EQUIPMENT GRANTS (0010)TYPE:%IDeA $:Infrastructure8.000% IDeA $: 280,806INVESTIGATOR, DEGREEGriffith, Robert PHDDEPARTMENTBasic PharmaceuticalSciencesNON-HOST INSTITUTION: STATE,COUNTRYWest Virginia University, Wv UsaTotal # human subjects expected for entire study: 0Total # human subjects enrolled to date: 0SUBPROJECT DESCRIPTIONAs part of the Faculty Research Development Program, grants are made available to partner institutions andresearchers to purchase equipment that will enhance the biomedical research infrastructure at the partnerinstitution. The maximum that could be requested was $30,000.SUBPROJECT PROGRESSIn order to enhance the research capabilities of the PUI schools we allocated funds to purchaseneeded laboratory equipment that could be directly related to ongoing biomedical research projects.The grants were limited items of equipment with a maximum of $30,000. We made the followingawards: Dr. Aguilar, West Liberty University, $6,139; Dr. Kreisberg, West Liberty University,$30,000; Dr. Fultz, West Virginia State University, $30,000; Dr. Chen, Alderson-Broaddus College,$26,200; Dr. Stover, Davis & Elkins College, $18,501; Dr. Wing, Shepherd University, $25,925; andDr. Sal, West Virginia Wesleyan College, $30,000.PROTECTION AGAINST RESEARCH RISKSN 1. Will human subjects be involved next year?N 2. Will vertebrate animals be used next year?N 3. Will recombinant DNA experiment(s) be conducted next year?N 4. Are there potential hazards to laboratory workers (carcinogens, pathogens, ionizing radiation, etc.)involved in the proposed research for next year? If yes, identify:N5. Will any of the research-risk categories,not involved next year, be involved future years? If yes, identify:PHS 2590 (Rev. 06/09)Continuation Format Page
Program Director/Principal Investigator (Last, First, Middle): Rankin, Gary OGENOMICS CORE (0033)25TYPE:%IDeA $:Infrastructure4.000% IDeA $: 156,114INVESTIGATOR, DEGREEPrimerano, Donald A PHDBoskovic, Goran PHDCuff, Christopher F PHDDementieva, Yulia PHDDenvir, James PHDFan, Jun BS, PHDGeorgel, Philippe PHDIvanov, Alexey PHDKim, Jung Han PHDSalisbury, Travis PHDZeng, Wei-Ping PHDDEPARTMENTBiochemistry &MicrobiologyBiochemistry &MicrobiologyMicrobiol, Immunol CellBiolMathematicsBiochemistry AndMicrobiologyBiochemistry &MicrobiologyBiological SciencesBiochemistryPharmacology,Physiology & ToxPharm, Physiol &ToxicologyBiochemistry AndMicrobiologyNON-HOST INSTITUTION: STATE,COUNTRYWest Virginia University, Wv UsaEmmanuel College, Ma UsaWest Virginia University, Wv UsaTotal # human subjects expected for entire study: 10Total # human subjects enrolled to date: 10SUBPROJECT DESCRIPTIONThe main objective of the Genomics Core Facility is to enable the genomic research goals of WV-INBREresearch projects. We provided the following services in Y11: (1) next generation sequencing, (2)microarray-based gene expression profiling and pathway analysis, (3) automated DNA sequencing andaccess to DNA/RNA sequence analysis software, (4) access to real-time PCR instrumentation, NanoDropspectrophotometers and Agilent BioAnalyzer for DNA/RNA analysis and (5) access to the Luminex 100 formultiplex protein detection. The Core will provide centralized genomic, bioinformatic and biostatisticalservices that are not available to individual labs and provide training in methods needed for completion of theresearch projects. These services will position project investigators to gather critical data efficiently andanalyze it with the most up to date bioinformatic and statistical tools. All Genomics Core Facility services areavailable to investigators at Marshall University (MU), West Virginia University (WVU) and WV-INBREPartner InstitutionsSUBPROJECT PROGRESSGenomics Core Staffing and InstrumentationDr. Donald Primerano served as the director of the Genomics Core Facility. He oversaw allGenomics Core services and insured that all projects were completed in a fair and timely fashion.Drs. Primerano and James Denvir oversaw the development of next generation sequencing (NGS)and delivery of all core facility services. Dr. Primerano advises Drs. Boskovic and Fan in thedevelopment of NGS and microarray protocols, ensures that projects are prioritized and completedin a timely fashion, provide training to COBRE investigators in NGS applications, and advertiseCore services via seminars and the MU website. Drs. Primerano, Denvir, Boskovic and Fan meetwith clients at the outset for planning of experimental design and for the review of the dataset at thePHS 2590 (Rev. 06/09)Continuation Format Page
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