Palm oil effects on some oxidative indices of diabetic rabbits229system. It could be that vitamin E being helped byother antioxidant components in the palm oilprevented the generation of free radicals andsubsequent oxidation. Similar synergistic action ofantioxidant nutrient has been reported (Chiu, etal., 1982).The work in essence shows that palm oilcontains some nutrients possibly antioxidantscapable of suppressing oxidative stress. Researchelsewhere suggests that vitamin E is a majoringredient. The work thus suggests that palm oilmay be a good antioxidative nutrient as itssupplementation decreased lipid peroxidation butincreased vitamin C level. The effect on glucoselevel was not pronounced, suggesting that theeffect could be more on the complications ofdiabetes.In conclusion palm oil may help toattenuate diabetes mellitus and possibly diabetescomplications. Its use may then be suggested inthe management of diabetic condition and indiseases associated with oxidative stress.REFERENCESALBRO, P. W. CORBETT, J. T. and SCHROEDER, J.L. (1986). Application of the thiobarturicassay to the measurement of lipidperoxidation products in microsomes.Journal of Biochemistry. 261: 4889 –4894.ARUOMA, O. I., KAUR, H. and HALLIWELL, B.(1991). Oxygen free radicals and humandisease. Journal of Royal Society Health,8: 172 – 177.ATKINSON, M. A. and MODOREN, N. K. (1990).What causes Diabetes? ScientificAmerican, July: 42 – 47.ATROSHI, F., ANTILA, E., SANK<strong>ARI</strong>, S.,TREUTHARAT, J., GAPOR, A., SALONIEMI,H. and WEITER M. T. (1992). Palm oilvitamin effects in hypercholesterolemia.Pages 243 – 254. In: ONG, A. S. H. andPACKER, L. (Eds.). Lipid solubleantioxidants: biochemistry clinicalapplication. Birkhauser Verg, Boston.BETHESDA, M. D. (1991). Guidelines for thediagnosis and management of Asthma.National Institute of Health, USDepartment of Health and HumanServices Publications, 91: 30 – 31.CHOO, Y. M., YAP, S. C., OOI, C. K., ONG, A. S. H.and GOLE, S. H. (1992). Production ofpalm oil carotenoid concentrate and itspotential application in nutrition. Pages243 – 254. In: ONG, A. S. H. and PACKER,L. (Eds.). Lipid soluble antioxidants:biochemistry and clinical applications.Birkhauser Verg Boston.CHIU, D., VICHINSKY, E. Y. M., KLEMAN, K. andLUBIN, B. (1982). Peroxidation of vitaminE and sickle cell anaemia. Annals of NewYork Academy of Sciences, 239: 323 –335.CHUNG, Y. M. I., CHIU, P. M. M. and WONG, H. L.(1992). Modification of alloxan diabetes inrats by vitamin A status. Pages 265 – 273.In: ONG, A. S. H. and PACKER, L. (Eds.).Lipid soluble antioxidants: biochemistryclinical application. Birkhauser Verg,Boston.COOPER, G.R. and McDANIEL, V. (1970). Assaymethods. Pages 159 – 170. In:McDONALD, R. P. (Ed.). Standardmethods for clinical chemistry. John Wileyand Sons, New York.DAS, B. S. THURNHAM, D. I. PATNACK, J. K. DAS,D. B. SATPATHY, R., and BASE, T. K.(1990). Increased plasma lipidperoxidation in riboflavin deficient malaria– infected children. American JournalClinical Nutrition, 51: 859 – 863.DAS, B. S. and THURNHAM, D. I. (1992). Plasmalipid peroxidation in Plasmodiumfalciparium malaria. Pages 397 – 405. In:ONG, A. S. H. and PACKER, L. (Eds.).Lipid soluble antioxidants: biochemistryclinical application. Birkhauser Verg,Boston.ELHADD, T. A., KHAN, F., KIRK, G., MCLAREN, M.and NEWTON, R. W. (1999). Influence ofpoverty on endothelial dysfunction andoxidative stress in young patients withtype 1 diabetes. Diabetes Care, 21: 1990– 1996.EZE, M. O. (1991). Production of superoxide bymacrophages from Plasmodium chandandiinfected mice. Cytobios, 66: 93 – 104.EZE, M. O. (1992). Membrane fluidity, ROS andCell mediated immunity; implications innutrition and disease. MedicalHypotheses, 37: 220 – 224.FREI, B. (1991). Ascorbic acid protects lipid inhuman plasma and low density lipoproteinagainst oxidative damage AmericanJournal Clinical Nutrition, 54: 1113 –1118.GALLUZZO, A. GIORDANO, C. and BOMPIANA, G.D. (1990). Cell-mediated immunity indiabetic pregnancy. Pages 273 – 278. In:Immunology of normal and diabeticpregnancy. John Wiley and Sons NewYork.GUTHERIDGE, J. M. C. (1994). Reactivity ofhydroxyl and hydroxyl – like radicaldiscriminated by release of TBARS fromdeoxysitrose, dudeosides and Beuroate.Biochemistry, 224: 761 – 767.
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