FIT FOR LIFE - Dr. Lindsey Duncan

The Doctors’ Prescription for
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Healthy
Living with
Dr. Lindsey
Duncan
Dr. Lindsey Duncan studied and worked
with the legendary and distinguished
detoxification expert, Bernard Jensen,
Ph.D., for several years, spending much
of his time assisting Dr. Jensen at his
famous healing retreat in Escondido, California.
Dr. Duncan completed his alternative
health education with dual degrees
in nutrition and naturopathy. He has
appeared as a nutrition and herbal expert
on most of the major news stations in the
U.S. and Europe (including those affiliated
with ABC, CBS, NBC, CNN and BBC
London). Dr. Duncan has accumulated
over 40,000 clinical hours helping people
restore their health. He has just
returned from an extensive tour of Thailand,
Vietnam and Northwestern China
bordering Mongolia where he was
researching the goji berry and the mangosteen
fruit. He is recognized as a leading
expert on these fruits and the science
of natural cleansing and detoxification.
THE AMAZING TRUTH ABOUT
Mangosteen’s
Xanthones
10 the doctors’ prescription for healthy living
by Lindsey Duncan, N.D., C.N.
during my public health seminars and interviews,
I am frequently questioned about
the validity of specific supplements and
asked to make comparisons. At any given time,
there is usually a product that has become popularized
as being a “cure-all.” Throughout my 20
years of practicing naturopathy, I’ve come across
thousands of nutritional supplements that fall into
this category. They fail miserably, without giving
any results at all, and avoid any “real” scientific
substantiation. In fact, they often make a problem
worse because people will quickly dismiss all
similar products. This has been especially true of
diluted noni and diluted goji juices. Recently,
more and more people are asking me about mangosteen
juice, which deserves to have its record
set straight.
XANTHONES
Mangosteen (Garcinia mangostana) is a fruit originating
from Southeast Asia, which flourishes in
extremely tropical climates. While enjoyed by many
as a table fruit, its therapeutic properties have long
been understood by the indigenous people of
Thailand, Vietnam, Cambodia, India, Indonesia
and China. It has been nicknamed “The Queen of
Fruits” and has been used for thousands of years
in folk and traditional medicine. Historically it was
used for inflammatory conditions of the bowel,
such as dysentery or diarrhea, as well as a solution
to control pain, disinfect wounds, and more.
So, what is the science behind mangosteen’s
rich history and what are the “key actives” that
make it so beneficial? Xanthones. Xanthones are
phytonutrients, which are natural anti-inflammatory
agents derived from nature and are one of the
earth’s most powerful antioxidants. Researchers
have discovered that mangosteen contains the
richest source of xanthones known to man, primarily
in its pericarp or rind. Of the 200 known
xanthones, over 40 of them are found in the mangosteen.
This abundance of xanthones accounts
for mangosteen’s healthful, therapeutic effects.
KEY BENEFITS OF
MANGOSTEEN’S XANTHONES
Natural Anti-inflammatory Properties
The active polyphenolic compounds known as
xanthones found in mangosteen’s pericarp have
been clinically shown to reduce the necessary
enzymes that are involved with the body’s natural
inflammatory processes. Many of you are probably
familiar with these enzymes: cyclo-oxygenase-
1 (COX-1), cyclo-oxygenase-2 (COX-2) and
prostaglandins. Pharmaceutical companies are
currently spending hundreds of millions of dollars
researching synthetic drugs aimed to inhibit these
enzymes and inflammation. Celebrex ® , Bextra ®
and Vioxx ® are examples of COX-2 enzyme
inhibitors that have been and are currently prescribed
to treat patients with severe osteoarthritis,
rheumatoid arthritis or other inflammatory conditions
associated with acute injury. Recently these
prescription medications have been seen in the
media as being potentially unsafe medications.
The Food and Drug Administration has asked the
manufacturers of Vioxx and Bextra to voluntarily
remove their products from the market due to
safety concerns. These two drugs are alleged to
cause an increased risk of cardiovascular events,
including heart attacks and strokes.
The benefits of reducing inflammation have
been extolled in the media and the medical community
throughout the world. Inflammation may be

the root cause for most all degenerative and
deadly diseases ranging from cardiovascular disease,
cancer, rheumatoid arthritis, and lupus to
Crohn’s and ulcerative colitis. Every day it is
becoming more and more apparent that reducing
inflammation in the body is critical. Mangosteen,
with its rich xanthone content, promotes healthy
inflammatory processes in the body.
A Natural, Strong Antioxidant—Helps
protect the body from free radical damage
Because mangosteen is rich in a wide range
of xanthones, which are also powerful antioxidants,
your body will be better able to fight free
radical damage. Free radical damage may manifest
itself as premature aging, elevated bad cholesterol
and oxidation, cardiovascular disease,
and cellular and DNA mutations, among other
undesirable and unwanted conditions.
A Natural Anti-histamine—Helps reduce
histamine levels and assists in the
reduction of allergies
Histamines are released by the body in
response to common allergens, such as dust,
pollen, foods, dander, and fungal toxins. The xanthones
in mangosteen have been shown to reduce
histamine release (in-vitro, that is, experimentally),
which may naturally support allergy relief.
A Natural Immune Stimulant
According to researchers throughout Asia,
these mangosteen xanthones have been clinically
researched to be strong immunostimulants. These
polyphenolic compounds can stimulate phagocytic
cells (which are responsible for attacking intracellular
bacteria, amongst other pathogenic organisms).
Current cellular research is very promising and indicates
that mangosteen’s xanthones may be effective
against cancer cell lines involved in liver, breast
and colon cancer, as well as leukemia. The main
beneficial mechanism of action is xanthones,
inducing apoptosis, also known as programmed
cell death (PCD).
Natural Antibacterial Properties
Due to the overuse of prescription antibiotics
worldwide, new super strains of drug-resistant
bacteria have mutated and have caused widespread
panic across the medical community. One
such strain is MRSA or methicillin-resistant Staphylococcus
aureus. Scientists have observed xan-
A list of some of the prestigious universities that
have been studying, documenting and publishing
studies on mangosteen for over 50 years:
❍ Mahidol University—Department of
Microbiology, Bangkok, Thailand
❍ Centre for Agrochemical Research,
Madras, India
❍ University of the Ryukyus—Tumor
Pathology Division, Okinawa, Japan
❍ Gifu International Institute
of Biotechnology, Gifu, Japan
❍ Chiang Mai University—Department
of Clinical Microscopy, Thailand
thones to exhibit strong experimental antibacterial
activity against MRSA and other super strains.
Natural Antifungal Properties
As with most natural key actives like xanthones,
those that show strong antibacterial activity
also show strong antifungal activity.
Offers a Wide Range of
Cardiovascular Support
As I previously mentioned, the strong antioxidant
activity of mangosteen xanthones supports
free radical scavenging, protecting low-density
lipoproteins (LDLs) from oxidative damage. This
may prevent the cholesterol
❍ National University of Singapore—
Department of Chemistry
❍ National Research Institute of
Chinese Medicine, Taiwan, ROC
❍ Royal Perth Hospital, Australia
❍ Srinakharinwirot University,
Bangkok, Thailand
❍ Tohoku University—Department of
Pharmaceutical Molecular Biology,
Sendai, Japan
➔ ➔ ➔
the doctors’ prescription for healthy living 11

The Amazing Truth About
Mangosteen’s Xanthones
continued
W e
from being oxidized, which is detrimental to the
entire cardiovascular system.
OBTAINING THESE
AMAZING BENEFITS
To really benefit from mangosteen, it is critical to
choose only a therapeutic, undiluted and unsweetened,
strong, and potent product that has been
tested for all its active compounds.
When choosing a mangosteen product, it is
my recommendation that you abide by the following
guidelines:
❍ Always choose mangosteen juice that utilizes
the entire fruit to ensure you are receiving all
the critical xanthones;
❍ Always choose a bioavailable liquid source;
❍ Always choose a 100 percent pure, undiluted
and unsweetened mangosteen juice product;
❍ Always choose a wild-harvested or certified
organic mangosteen juice product;
❍ Always choose a product that has been made
with “table quality” mangosteen and avoid
those produced with “ground harvest” or
“industrial waste” fruit;
❍ Always avoid added sweeteners, additives,
artificial flavors and fillers, a sure sign of inferior
quality;
❍ Always avoid mangosteen juice with “other”
added fruit juices, such as cherry, cranberry,
raspberry, peach, pear, grape—again, this
often indicates lesser quality.
DR. LINDSEY’S NATURAL
HEALTH PRESCRIPTION
While there is no “cure-all” herb or plant, there are
certainly plants that can offer health benefits. If
you’re interested in trying a mangosteen product,
I urge you not to be influenced into trying something
inferior. Review the above list carefully and
choose an efficacious, potent, pure, authentic and
undiluted mangosteen juice. As we in the West are
just being introduced to the health benefits of this
amazing fruit, I recommend that you try only the
purest mangosteen you can find for yourself. You
should be able to experience the positive benefits
before you finish your very first bottle. ■
Healthy Living’s Mangosteen Best Bet
are grateful to Dr. Lindsey Duncan for lending his expertise to understanding the science of xanthones and the
health benefits of mangosteen. As we’ve gotten to know Genesis Today, we’ve come to see that their juice products
are probably unparalleled in the natural products industry. Dr. Lindsey
has made us believers in 100 percent pure and potent noni and goji
juices and, based on his advice, we are adding mangosteen to our
list of daily super juices that you will want to take advantage of for
their superior health benefits.
We recommend Genesis Today’s Mangosteen100 as the richest
source of bioavailable mangosteen xanthones. Genesis Today has
gone to great extremes to bring an authentic, pure, thick, powerful,
xanthone-loaded mangosteen product to the West.
Mangosteen100 is a proprietary blend of the whole mangosteen
fruit, including the white pulp meat, the seeds, the thick, tough and
bitter inner rind and the outer rind (pericarp) and boasts 30,000 mg
of mangosteen in each 1 fl. oz serving. From our research we have
found no other product in the world providing those levels of
mangosteen or xanthones in a single serving.
This article is for educational purposes only and is not recommended as a
means of diagnosing, preventing or treating any illness. The statements in
this article have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
VIOXX ® is a registered trademark of Merck & Co., Inc.
Bextra ® and Celebrex ® are registered trademarks of G. D. Searle & Company.
12 the doctors’ prescription for healthy living
According to William Brescia, head of
Research and Development, Quality
Control and Quality Assurance at Genesis
Today other companies ship dried mangosteen
powder to the U.S. and then reconstitute it with
water and other fruit juices. We know of no other
company that produces their Mangosteen juice like
Genesis Today: from whole, fresh, table-quality fruit
and adds nothing to it. Genesis Today follows its
mangosteen fruit from each of their wild harvest
farms, through all stages of processing, shipment,
testing and finally to the shelf. By actively managing
and overseeing the entire process (see the photos to catch a glimpse
of CEO and Founder Dr. Lindsey Duncan touring one of their wild harvest
farms), Genesis Today can maintain a quality mangosteen product with the
highest levels of active xanthones. For a copy of mangosteen’s clinical
studies, scientific validation and documentation, and Mangosteen100’s
Certificate of Analysis, please contact (800) 916-6642 or visit
www.genesistoday.com.
We actually reviewed the Genesis Today Certificate of Analysis and
made note of two outstanding things:
❍ All laboratory testing has been done by an independent facility without
any affiliation to Genesis Today.
❍ Unlike other companies, Genesis Today tested seven different samples
of Mangosteen100. Most companies test only one sample.