Non-Invasive Blood Pressure

Non-Invasive Blood PressureProven system for reliably measuring systemic blood pressure in rodentsPRODUCT OVERVIEWPanlab NIPB system provides an easy andreliable technique to measure systemic bloodpressure and cardiovascular parameters inrodents without any invasive catheterisation.Given that the success of the experimentmainly relies on the animal manipulation,specific effort has been made in engineeringa system that provides the best conditions forobtaining reliable data with a minimum numberof attempts. For this purpose, the system hasbeen designed for simplifying to the maximumthe settings of the equipment as well as forminimizing animal stress during the wholeprocedure.The Panlab NIBP system is also the only systemin the market that proposes complete solutionsfor ensuring the traceability and validations ofthe data obtained!Over 100 citationsworldwide!Key Features• Total reliability to realise consecutive measurementson the same animal• Analogical Signal output for enabling cuffpressure and pulse signals registering• Automated deflation driven separately for eachanimal (minimize tail lesions)• The same system can be used for Rat / Dog /Mice (1 transducer by specie)• Extremely easy to use (only 1 setting button!)• Validated for its use in anesthetized animals• Real values provided (without any linear regressioncalculation)• Easily traceable data (using a data acquisitionsoftware)• Parameters evaluated can be visualized on-lineon the digital displayAPPLICATIONSCARDIOVASCULAR - Non-Invasive Blood Pressure, Drugscreening, Phenotyping, Hypertension/hypotension studies,Obesity, Kidney disease studies, Addison’s disease studies,Sepsis, Toxin reaction studies.LeafletLF0832CPANLAB s.l.u. 01

Maximum simplification!• Same system for Rat / Dog / Mice• One single button allows adapting an internalfilter to the specific characteristics of the signalfor these three different species.• One single transducer/Cuff for all sizes of animalinside the same specie.• Impressively easy to use! Only 2 buttons: gainsetting and start.• Message on the LCD display indicates when theanimal is ready for starting measurement!• One of the few equipment in the market allowingNIBP experiment in anesthetized animals!!!!Contact us for more information...CUFF & TRANSDUCERSOnly one transducer by specie!• One single transducer/cuff model by specie(mice, rat, dog).• Optimal transducer accuracy insured by thepressure method (respecto photocell method).• Transducer clamp system guarantees that it canbe used for any tail size.HOLDERSLE5160MMice & Rats upto 150 grLE5160RRatsLE 5015/LE 5012Dogs• Perspex cylinderswith slidingdoors mountedon a flat blackPerspex base.• Special dooraperture tolet the tail accessible for cuff and transducerinstallation• Available in 6 different sizes, the restrainerscover all the range of rat & mice.Minimizing animal stressIn non-invasive blood pressure procedures, havingan “enough relaxed” animal is mandatory to obtainaccurate data. For this purpose, Panlab NIBP equipmentis specifically designed for minimizing animal stressduring the procedure.• Automatic decrease of the pressure of the cuffwhen occlusion is detected avoiding to applyunnecessary pressure on the tail that may damageit and make difficult obtaining reliable data.• Automated deflation driven separately for eachanimal (minimize tail lesions)• Noiseless pressure pump• Adapted accessories (transducers, holders andheaters)HEATERSChoose between our two heater options which providea comfortable and heated environment necessaryto produce peripheral vasodilatation and isolate theanimal from external noise.Individual heater• Individual heaterfor rat and mousewith temperatureadjustable from roomtemperature to 38ºCAutomated heater and scanner• Automated heater with temperature adjustablefrom room temperature to 38ºC• The heater is provided with switches for controllingup to 6 animals sequentially.• The switch function can be performedautomatically or programmed using the LE 5007.• Up to 2 units can be connected ensure thesequential measurement of 12 animals withouthaving to change the pulse transducers and tailcuffs.• A fan ensures appropriate air flow and correctdispersion of the heat produced by a system ofelectronically controlled resistances.PANLAB s.l.u. 03

Non-Invasive Blood PressureDATA OUTPUT TO PCProvided with basic SeDaCom PC interfaceSeDaCom software increases the functionality ofthe equipment allowing the transfer of data from thecontrol units to PC for storage and further analysis.SeDaCom uses RS232(USB) port communication(RS232/USB has to be purchased separately) andis provided without additional cost. Data can bedisplayed on thecomputer and print outin real-time. Results arestored in ASCII formatfor full exportability toother program as Excel.Advanced options for complete data traceability!Visualize the pulse and cuff pressure signals for a graphicaldetermination and checking of the values measured by theequipment by using:• BNC/USB directconnection to theNIBPchart software• BNC data outputsto a user’s Logger,Oscilloscope orData Acquisitionsystem.ORDERING INFORMATIONNIBP UNITSLE5001 76-0173Basic unit for N.I.B.P. with RS232 comms. Port. Includes SedaCom software. Cuff, transducerand RS232/USB converter have to be ordered separately.LE5002 76-0174Standard Unit for N.I.B.P. with Memory and RS232 comms. port. Includes SeDaCom software.Cuff, transducer and RS232/USB converter have to be ordered separately.LE5007 76-0175Complete Unit for N.I.B.P. with Scheduled data acquisition (up to 12 animals) Memory andRS232 comms. port. Includes SeDaCom software. Cuff, transducer and RS232/USB converterhave to be ordered separately.OPTION CONRS232USB 76-0608 RS232/USB converterCUFF & TRANSDUCERSOPTION LE5160M 76-0012 Pulse transducers & cuff (diameter 7 mm) for mice and rats up to 150 gramsOPTION LE5160MM 76-0432 Pulse transducers & cuff (diameter 6 mm) for miceOPTION LE5160R 76-0013 Pulse transducer & pressure cuff for ratsOPTION LE5015 76-0014 Pulse transducer for dogOPTION LE5012 76-0015 Pressure cuff for dog (diameter 18 mm)HEATERSOPTION LE5610 76-0178 Heater for single animal (includes reference LE5095)OPTION LE5095 76-0401 Transducer & holder fi xing plateOPTION LE56506 76-0179 Automatic Heater & Scanner for six rats or six miceOPTION LE56606 76-0179 Automatic Heater & Scanner for six miceHOLDERSOPTION LE5016 76-5016 Mice holder (small animals); 90 x 30 mmOPTION LE5018 76-5018 Mice holder (large animals); 100 x 34 mmOPTION LE5020 76-5020 Rat holder (150 gr.); 150 x 44 mmOPTION LE5022 76-5022 Rat holder (250 gr.); 180 x 54 mmOPTION LE5024 76-5024 Rat holder (400 gr.); 200 x 64 mmOPTION LE5025 76-5025 Rat holder (500 gr.); 225 x 74 mmCHART VISUALIZATION & REGISTERINGOPTION NIBPCHART 76-0466NIBPchart software option for data traceability and validation. Monitoring of cuff pressure andpulse waves signals (includes USB connection).OTHER ACCESSORIESOPTION LE5090 76-0177 Electronic Rat SimulatorPanlab s.l.u.C/Energía, 11208940 Cornellà(Barcelona) SPAINPhone: +34 934 750 697 (Int.)Phone: 934 190 709 (Dom.)Fax: +34 934 750 699info@panlab.comwww.panlab.com04PANLAB s.l.u.