CNS presentation of Lyme disease

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What do we need to make diagnosis ofneuroborreliosis ?• Symptoms• Serological confirmation‣ corner stones for diagnosis• symptoms are not specific,• serology is neither reproductible, neither relevant of evolutivedisease‣ This lead to wrong diagnosis– All symptoms are considered– Serological testing are mis interpreted• … can we isolated the bacteria ?
Lyme borreliosismicrobiology• Three main species– B. burgdorferi sensu stricto– B. garinii– B. afzelii• Other species– B. valaisiana,– B. lusitaniae,– B. spielmannii.• Epidemiology– B. Burgdorferi in United States– In Europe all species are present‣ Is it really the same disease ?
Page 5 and 6: The answer• If your referenceis
Page 10 and 11: Lyme diseasethe three steps of diag
Page 13 and 14: Microbiological Epidemiology- infes
Page 17 and 18: Symptoms of Lyme borreliosiskinetic
Page 19 and 20: Early LNB• PNS manifestations.- m
Page 21 and 22: Late neuroborreliosis• PNS manife
Page 23 and 24: Neuroborreliosis an exemple in a re
Page 27 and 28: Serology two-step approachScreening
Page 29 and 30: Western blot• First antibodies in
Page 31 and 32: Diagnosis criteria
Page 33 and 34: European national neurological soci
Page 35 and 36: Antibiotic choice for neuroborrelio
Page 37 and 38: Doxyxyclin and neuroborreliosis•
Page 39 and 40: Treatment of nervous system Lymedis
Page 42 and 43: Some specific situations
Page 44 and 45: Late stage neuroborreliosis• Ther
Page 46 and 47: Follow up• No correlation between
Page 48 and 49: Koch’s postulate• The microorga
Page 50 and 51: The polemic• Some patients « see
Page 53 and 54: Aim of the study• Evaluate the po
Page 55: Conclusion• Right diagnosis is im

CNS presentation of Lyme disease

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