CNS presentation of Lyme disease

European national neurological societiesguidelinesMygland et al. Eur J Neurol, 2010 ; 17• Adult patients with Bannwarth syndrome– single 14-day course of antibiotic treatment.– Oral doxycycline or IV ceftriaxone or IV penicillin or IVcefotaxime are effective and safe treatments (level B).– Oral doxycycline (200 mg daily) and IV ceftriaxone (2 gdaily) for 14 days are equally effective (level A).• Adult patients with early LNB with CNSmanifestations– IV ceftriaxone (2 g daily) for 14 days