CNS presentation of Lyme disease

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Treatment <strong>of</strong>neuroborreliosisEvidence based review
Antibiotic choice for neuroborreliosis• High-dosage intravenous penicillin is aneffective treatment for neuroborreliosis– Steere AC, et al. Ann Intern Med 1983; 99: 767–772.• Ceftriaxone showed equivalence or a betterefficacy at 2 g/day than penicillin.– Dattwyler RJ, et al. Lancet 1988; 1: 1191–1194.– Pfister HW, et al. Arch Neurol 1989; 46: 1190–1194.
Page 5 and 6: The answer• If your referenceis
Page 8 and 9: What do we need to make diagnosis o
Page 10 and 11: Lyme diseasethe three steps of diag
Page 13 and 14: Microbiological Epidemiology- infes
Page 17 and 18: Symptoms of Lyme borreliosiskinetic
Page 19 and 20: Early LNB• PNS manifestations.- m
Page 21 and 22: Late neuroborreliosis• PNS manife
Page 23 and 24: Neuroborreliosis an exemple in a re
Page 27 and 28: Serology two-step approachScreening
Page 29 and 30: Western blot• First antibodies in
Page 31 and 32: Diagnosis criteria
Page 33: European national neurological soci
Page 37 and 38: Doxyxyclin and neuroborreliosis•
Page 39 and 40: Treatment of nervous system Lymedis
Page 42 and 43: Some specific situations
Page 44 and 45: Late stage neuroborreliosis• Ther
Page 46 and 47: Follow up• No correlation between
Page 48 and 49: Koch’s postulate• The microorga
Page 50 and 51: The polemic• Some patients « see
Page 53 and 54: Aim of the study• Evaluate the po
Page 55: Conclusion• Right diagnosis is im

CNS presentation of Lyme disease

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