CNS presentation of Lyme disease
CNS presentation of Lyme disease CNS presentation of Lyme disease
Symptoms of Lyme Borreliosishistorical features• Skin manifestations known since more than100 years– Afzelius in 1909 : Erythema migrans– Buchwald in 1883 : Acrodermatitischronica atrophicans• Neurological manifestations– Garin and Bujadoux in 1922 meningoradiculitisafter tick bite– Also call : Bannwarth’s syndrome• Articular manifestations Steere in 1977 :Lyme disease• Correlation between Borrelia and Lymedisease in 1982
Symptoms of Lyme borreliosiskinetic features• Primary Lyme disease– Following some days to some weeks after tick bite• Early or Secondary Lyme disease– Approximately from three weeks to 3 months after tickbite• Late manifestations– More than several month evolution• Post Lyme disease– Sequellae ?
- Page 5 and 6: The answer• If your referenceis
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- Page 10 and 11: Lyme diseasethe three steps of diag
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- Page 19 and 20: Early LNB• PNS manifestations.- m
- Page 21 and 22: Late neuroborreliosis• PNS manife
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- Page 27 and 28: Serology two-step approachScreening
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- Page 31 and 32: Diagnosis criteria
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- Page 37 and 38: Doxyxyclin and neuroborreliosis•
- Page 39 and 40: Treatment of nervous system Lymedis
- Page 42 and 43: Some specific situations
- Page 44 and 45: Late stage neuroborreliosis• Ther
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- Page 48 and 49: Koch’s postulate• The microorga
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- Page 53 and 54: Aim of the study• Evaluate the po
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Symptoms <strong>of</strong> <strong>Lyme</strong> Borreliosishistorical features• Skin manifestations known since more than100 years– Afzelius in 1909 : Erythema migrans– Buchwald in 1883 : Acrodermatitischronica atrophicans• Neurological manifestations– Garin and Bujadoux in 1922 meningoradiculitisafter tick bite– Also call : Bannwarth’s syndrome• Articular manifestations Steere in 1977 :<strong>Lyme</strong> <strong>disease</strong>• Correlation between Borrelia and <strong>Lyme</strong><strong>disease</strong> in 1982
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