12.07.2015
•
Views
:::22recogrnize vre professional people are reluctant to change from a habitor course that we have been foUowinir. But would it te desirable to putin perspective the necessity of balancin
:::::.—23American Society of Pharmacology and Experimental Therapeutics, 1930-Council, 1937; membership committee, 1942, 1943, 1944 (chairman);president, 1946, 1947; nominating committee, 1949, 1950American Physiological Society, 1933-(chairman)Federation of American Societies of Experimental Biology ExecutiveCommittee, 1946, 1947 (chairman), 1948Society for Experimental Biology and Medicine Council,American Medical Association1950-1953Vice-chairman, Section of Experimental Medicine and Therapeutics1951-1052Chairman, 1952-1953Member, Council on Drugs (formerly Council on Pharmacy and Chemistry)1952-1962* Member—Committee on Alcoholism and Drug Dei>endence—Council onMental Health, 1964-Chairman—Committee on Research on Tobacco and Health AMA-ERF1964-Honorary membershipsAmerican Society of Anesthesiology.Japanese Pharmacological Society.Committees and consultantshipsMember—Board of Scientific Counselors, National Heart Institute, NationalInstitutes of Health, 1957-1960.Member—Drug Abuse Panel, President's Advisory Committee—WhiteHouse Conference on Narcotic and Drug Abuse, 1962-1963.Member—Surgeon General's Committee on Smoking and Health, Departmentof Health, Education, and Welfare, 1962-1963.Chairman—Committee on Behavioral Pharmacology—PsychopharmacologyService Center-National Institutes of Health, 1964-1968.American coordinator—U.S. Japan Cooperative Program on Drug AbuseNational Science Foundation and Japan Society Promotion of Science,since 1964.Member—President's Commission on Marihuana and Drug Abuse, 1971-72(established by Public Law 91-513)EditorialBoard of publication trustees, American Society for Pharmacology and ExperimentalTherapeutics, 1948, chairman, 1949-1961.Editorial board. Physiological Reviews, 1943-1951.Editorial board. Proceedings Society for Experimental Biology and Medicine,1944-1959.Editorial committee. Annual Review of Pharmacology, 1959-1962.InternationalWHO (United Nations) Expert Advisory Panel on Drugs Liable to ProduceAddiction, 1951-Second Medical Mission to Japan, May-June, 1951 Unitarian Service Committeeand Department of the Army.U.S. National Committee for International Union of Physiological Science,Chairman American team—Conference on Physiologic and PharmacologicBasis of Anesthesiology—Japan, April-May 1956.Consultant—Minister of Public Health of Thailand—Bangkok, May 2-17,1959Consultant, Minister of Health and Welfare of Japan, Tokyo, 1963-.AwardsThird Class of the Order of the Rising Sun 6f Japan, 1963.Distinguished Service Award Washburn University Alumni Association,1964. ^^ .„„_Second Class—Order of the Sacred Treasure of Japan, 1967.^Henrv Russell Lecturer—The University of Michigan, 196 (.J Y. Dent Memorial Lecturer—Kings College-University of London, 1968.Certificate of Commendation from Minister of State Director-Geneial,Prime Ministers Office, Japanese Government, October 1969.•Current appointments.
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NARCOTICS RESEARCH, REHABILITATION,
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::VEXHIBIT NO. 4 (a) AND (b)Eddy, D
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NARCOTICS RESEARCH, REHABILITATION,
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urden that such addiction imposes u
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1 (lata; (->) the sliariiis" oF iii
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9Chairman Pepper. The committee is
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::11quota production from unrecogni
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13in this country. This raises the
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15from other clinical projects of w
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:17practice, experience has indicat
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;19.I think a quota would be better
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21When methadone was first introduc
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_'—25.I'BOCUREMENT AND ISSUE DATA
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'.28Fiscal years-1967 1968 1969 197
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30rally in opium. By indirect, the
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32We can, I think, most helpfully g
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34so intense that we haven't done v
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Dr. Eddy. Well, physicians, usually
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38Dr. Eddy. No.Chairman Pepper. Now
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:40get away with it as Dr. Keats su
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:—:42public health hazard was jud
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:44Bibliography(1 Nathan B. Eddy. "
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46(52) Nathan B. Eddy. "Dilaudid."
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48(98) "The New Narcotics, Post-gra
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^.50
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52entails the consideration of addi
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54Chairman Pepper. Have you found t
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56^.I wonder would you care to comm
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58Chairman Pepper. Without objectio
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—1958-681959-«419691962-64196219
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—62abuse and has brought about th
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64bank robbery or an assault. You d
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66Mr. Wiggins. Would the stopping o
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68—Chairman Pepper. Can you give
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:70The problem then would be the wi
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;72taking exceptional measures in t
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)—74pay serious attention to this
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;76From 1958 to 1961, he served as
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78deine in painkilling drugs. So if
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;80ning capabilities, responsibilit
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;:;82terials. If they could introdu
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84Figure 1infrared Ektachrome film
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;86Figure 3.—Tones of wheat (W) a
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88ers at the poppyfields or at any
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:90;:tional situations has handicap
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;;92Locating illicit opium cropsDet
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94Jaffe. Well, there would be some
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96Mr. Jaffe. Primarily on the fact
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98in the same ball park about what
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100Chairman Pepper. Mr, Waldie, do
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::102agencies and input data would
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104most facilities are barely able
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;106We have also studied a ^roup of
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108Dr. Gearing. Yes, sir; I would n
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110somethino: in the nei
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112program is put into the machiner
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I114you have some data there that s
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116Dr. Gearing. It depends on what
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118Chairman Pepper. Would you have
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120it not be so that we could proje
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.122admission rate was approximatel
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124BESULTS(1) Although many of the
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1262. All the members of the methad
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128HETHADOHE MAINTENANCE TREATMENT
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11 1 1 1 1 11130Methadone Halnten?n
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132TABLE 2.-METHAD0NE MAINTENANCE T
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134Figure 9 Methadone tlaintenance
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136Methadone Ka'ntanance Treatmf:nt
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:::.::.138Appendix A^—Methadone M
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140nance treatment patients showing
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142Figure 3 •lethadone Kaintenanc
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144Dr. DuPoNT. 1,760 on methadone m
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:146there are dramatic reductions i
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148Health insurance coverage for me
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Page 162 and 163:
150Dr. DtjPont. Well, there are no
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152Mr. Blommer. You would agree the
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154done. Where is the evidence ? No
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156There are several reasons a pers
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158It would seem to me a very busy
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160we had before. I don't think it
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162heroin addiction and support all
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164Dr. DuPoNT. I am reluctant to ge
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166Using this figure as rule of thu
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)168ment facilities for heroin addi
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.170parole departments. None were c
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::172Table 2.— Selected character
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174TABLE 3.—HEROIN ADDICTION RATE
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176W.a^^cc-V.c Cffv..AdF-ro ftcoKjL
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178.^06V f\QrK-'SEt G^ouP/AJ6SIS're
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I180*i coo)u->CM>—'CMUJCOO O COa>
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I(/I182esiMmin0)^> oo.00 =E|c O.2 o
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184encouraged to return to methadon
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186or other side effects. This incr
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:188number as that on the bottle. W
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190Attachment ThreeTo all medical s
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-jI IALLI192ATTACHMENT- FIVE,J: IPA
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194ATTACHMENT NINEGOVERNMENT OF THE
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......—196half of the addicts sta
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198CONCLUSIONSCertain patterns emer
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200TABLE 5.— PROFILE OF BARBITUAR
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202TABLE ll.-SUPPORT OF HEROIN HABI
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Page 216 and 217:
204TABLE 17.-AGE OF ADDICTS AND NON
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206TABLE 23.—PRESENT MARITAL STAT
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208TABLE 28.-MILITARY SERVICEAddict
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:210The committee is pleased to cal
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212sists of a network of 21 geograp
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214(6) Basic studies on the nature
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216in fact, constitute autonomous o
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Chairman Pepper. Mr. Perito?218;; M
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^'220is not a very forgiving drug.
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'222Furthermore, in our present con
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—224the Federal Government decide
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-—I have presented one generic ki
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,clinic;?,>•
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230I realize we are running late.Do
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''232'']Vir. Winn. Tiien you mentio
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234So having put it in the area, ha
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,Memberships'—i236privilege of co
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;238A central hypothermic response
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;240South Bronx, Bedford-Stuyvesant
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242€are of patient addicts. We ha
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Page 256 and 257:
244hospitals in the city, came into
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246that came into my office, and I
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Page 260 and 261:
'Mr.;>•/nmo'.i,,;248deputy commis
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:250two Rockefeller Institute physi
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Page 264 and 265:
:252during pliase II that serious e
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254well-structured methadone mainte
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;:256nonsense and serves only to ad
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:258you best complete your statemen
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Page 272 and 273:
260Mr. Pertto. Based upon your expe
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262A a'reat case in point was a con
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«264Mr. Steiger. Did you discuss w
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—:266Mr. HoRAN. We don't support
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268Mr. Horan, let's back up a littl
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270It is not up to heroin or morphi
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272nesses yesterday who brought out
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274;Mr. Perito. It is my understand
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276So that at the end of the week t
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278steroid he lias in him we might
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Page 292 and 293:
280Mr. Perito. You are referriii"'
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282not drug free. I can say approxi
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28 A$2-a-day habit these individual
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•As286I got to the point once in
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Page 300 and 301:
288Mr. Steiger. You mentioned anoxi
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Page 302 and 303:
290Mr. Eangel. I could see then tha
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292Dr. Casriel. Mr. Keating, I have
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j294What period of time are ^ve tal
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296was March of 1970—he was admit
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298"The paper by Dole and Nyswander
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:300vent them from coming to New Yo
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302[Exhibit No.14(b)]Casriel Instit
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304to result from the insuflScient
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306It is this role of the intervent
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308EESULTSStudies concerning tlie p
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Page 322 and 323:
310The method derives from a specia
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Page 324 and 325:
312Why is this happening? What need
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m)effective with uncured alcoholics
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Page 328 and 329:
I316Casriel, who is medical-psychia
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Page 330 and 331:
318resort to heroin. One must not f
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.320in Permanent Cure of Narcotic A
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322!(4) '-Modification of Adaptatio
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324sections of the country, all sor
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;Mr.Pertto.niuch,I?,Mr. Peritq. Tha
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328Chairman Pepper. Mr. Steiger.Mr.
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, Mr., In''wMr, WiNx.nltiiink tlie
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:332"Stomach cramps" were found to
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'i.We334'""^li'anTOanl^ETPPEiL That
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:))))336would be deprived of any cl
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338less abuse liability than agents
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NARCOTICS RESEARCH, REHABILITATION,
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CONTENTSApril 26 1April 27 77April
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:•vEXHIBIT NO. 4 (a) AND (b)Eddy,
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Page 359:
:lovernor,vnEXHIBIT NO. 21 (a) and
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342have no desire to preempt the au
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344We hope these hearings will prov
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346tons in 1962 and to 155 tons in
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348SOUTHEAST ASIAAs you know also,
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350I would also point out as I did
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Page 372 and 373:
352their farmers who have been grow
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354told that much of the insurgency
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356Mr. IxGERSOLL. Well, again, Mr.
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358jority of the heroin problem in
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Page 380 and 381:
360years, but I have been frustrate
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Page 382 and 383:
362Mr, Steiger. If you were goin^ t
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364report marihuana among junior gr
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366And it seems to me tliat we Avou
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?368effectively, then maybe we will
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Page 390 and 391:
370improvement as far as the abilit
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Page 392 and 393:
372was there. Your visits probably
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374the purchase of Avitnesses—I s
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:376administrations to publicly say
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Page 398 and 399:
378Chairman Pepper. We will take a
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Page 400 and 401:
380Mr. Ingersoll. No. I don't recal
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:382can fulfill the vow made by the
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384have to give you the same answer
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Page 406 and 407:
386Mr. Brasco. But that is another
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Page 408 and 409:
388Mr. Ingeksoll. Well, that is the
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NARCOTICS RESEARCH, REHABILITATION,
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Page 413 and 414:
-39,3,Dr. Edwards held a surgical f
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395of Narcotics and Dangerous Drugs
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Page 417 and 418:
397Naloxone, recently approved for
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Page 419 and 420:
399for example, who might be abusin
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Page 421 and 422:
401Now, because of our attention ha
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Page 423 and 424:
403and this is only for the investi
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Page 425 and 426:
405effects this drug will produce i
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Page 427 and 428:
407Now, if it is not used intravene
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Page 429 and 430:
409Mr. Wiggins. Dr. Jennings, does
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Page 431 and 432:
411Penicillin is good for pneumonia
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Page 433 and 434:
413Mr. R ANGEL. But from the studie
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415Dr. Gardner. Again, we don't hav
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Page 437 and 438:
417Dr. Edwards. I suspect it at lea
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419On the other hand, if serious si
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Page 441 and 442:
421of the best known programs. Alth
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423Medical Association, American Ps
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Page 445 and 446:
425of the United States Pharmacopei
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Page 447 and 448:
4275. Repeated examinations. Physic
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Page 449 and 450:
429agement and rehabilitation of se
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—431As the agenc.v within HEW whi
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433and complex acts such as driving
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Page 455 and 456:
435(Inig induces physical and psych
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Page 457 and 458:
437Chiiirmtin Pepper. Doctor, I thi
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Page 459 and 460:
439A large proportion of youngsters
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Page 461 and 462:
441Dr. Brown, what would you say is
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Page 463 and 464:
443Chairmiui Pepper. Wliat is tlie
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Page 465 and 466:
446The state of the art is promisin
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Page 467 and 468:
447Lot nie ask you first, is tlic d
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Page 469 and 470:
449Chairman Pepper. Do you happen t
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Page 471 and 472:
451want you to take a look at. We w
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Page 473 and 474:
453In addition to that, there seems
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Page 475 and 476:
455the Mfldict is having a program
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Page 477 and 478:
457—on drugs? By that I mean, vei
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Page 479 and 480:
459\\ e are basically saying, in or
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Page 481 and 482:
—;461that this is the extent to w
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Page 483 and 484:
463We could go into the drug area a
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Page 485 and 486:
.465program that was i)ut into Jack
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Page 487 and 488:
467Mr. Brasco. Possibly. However, w
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Page 489 and 490:
469him, arrange to get somebody els
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Page 491 and 492:
471ainpheta.mines, or barbiturates.
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Page 493 and 494:
473In the meantime, the Institute d
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Page 495 and 496:
475treated in the community centers
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Page 497 and 498:
477research on narcotics in the sam
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479c 53 03E
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Page 501 and 502:
NARCOTICS RESEARCH, REHABILITATION,
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Page 503 and 504:
483spending for research through NI
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Page 505 and 506:
485There has been no concerted seri
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Page 507 and 508:
487it is left in one of their veins
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Page 509 and 510:
489I do not think I should explain
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Page 511 and 512:
491Dr. ViLLARREAL. Until the reflex
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Page 513 and 514:
493evidence strongly shows is that
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495Chairman Pepper. One other quest
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Page 517 and 518:
497Dr. ViLLARREAL. So, it is a biol
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Page 519 and 520:
'.499could result in a laboratory s
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Page 521 and 522:
5qifinds it in normal exploration.
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Page 523 and 524:
503synthesized a large number of na
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Page 525 and 526:
505STATEMENT OE DR. ALBERT KURLAND,
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Page 527 and 528:
507discovered if we iiad taken the
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Page 529 and 530:
509Mr. Perito. Dr. Kurland, do you
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Page 531 and 532:
511Chairman Pepper. Has the Food an
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Page 533 and 534:
513]Mr. Steiger. Do you feel from y
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Page 535 and 536:
515In this second study there was a
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517were any significant differences
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Page 539:
519The Deceptive Communication and
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Page 542 and 543:
.522than a State psychiatric hospit
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Page 544 and 545:
524Department of Mental Hygiene), R
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Page 546 and 547:
TABLE 3—COMPARISON OF THE 1ST POS
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Page 548 and 549:
528TABLE 10—RELATIONSHIP OF AGE T
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Page 550 and 551:
530tution and his involvement in th
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Page 552 and 553:
Attachment No. 5;r\ N-CH,-CH=CHo ,
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Page 554 and 555:
'-534Chart No. U (case No. 672)Disp
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Page 556 and 557:
536Chart No. 4 (case No. 694)Illust
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Page 558 and 559:
538Chart No. 35 {case No. 697)Excep
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Page 560 and 561:
540This amount of heroin is roughly
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Page 562 and 563:
5msuccessful or not in that short a
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Page 564 and 565:
544Chairman Pepper. Would you repea
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Page 566 and 567:
54^creased amount of licit as well
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Page 568 and 569:
—54Sand the bureaucracy and the a
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Page 570 and 571:
,,Mr.550you have used some of the s
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Page 572 and 573:
552so many areas is also a pitiful
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Page 574 and 575:
55,4nitiide of heroin addiction in
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Page 576 and 577:
556reached $976.5 billion, we can w
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Page 578 and 579:
558Mr. Jones was appointed to the c
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Page 580 and 581:
560cant when you consider that Out
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562criminal act in his lifetime. Ye
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—564Mr. Perito. Would it be fair
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566Now, Dr. Cliambers, can yon resp
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—568Mr. Raxgel. Our distinguished
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Page 590 and 591:
;-570Mr. Jones. That is correct. Ou
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572the commissioner, $186 million i
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Page 594 and 595:
574there should be something in the
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Page 596 and 597:
576and the way in which the funds a
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Page 598 and 599:
57SDr. Chambers. I think wliat you
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580Education is the best way of pre
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Page 602 and 603:
58-2Certain essential facts must re
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584done through determined action,
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586druffs, has the Nation's largest
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:588To repeat, methadone maintenanc
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:590I believe the Federal Governmen
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:take no such satisfaction. We have
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594of value in the testimony you ha
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596gone ahead with several. We have
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Page 618 and 619:
598force within our State Police De
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60PRased on the proposed goal of 2.
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602STATEMENT OF HON. MILTON SIIAPP,
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(51)4and apprehend the wholesalers
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J'606[Exhibit No. 23Prepared Statem
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608Under our 1071-72 budget proposa
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GIOcenters for the treatment of her
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Page 632 and 633:
. Dr.612Bourne informs me that we h
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614Governors in Atlanta to which re
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Page 636 and 637:
616pretty bad news, because it indi
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618Scientific statistical ioformati
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620((')) Finally, I believe that al
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622Governor Carter. I certainly rec
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624programs that are now available,
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626all of the top officials in the
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Page 648 and 649:
628perhaps greater than some of the
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)630tion and many others attempting
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632(3) Long term residential self-h
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Page 654 and 655:
634for the support of drug service
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Page 656 and 657:
:636D. NARCO, Inc.Narcotics Addicti
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638crimes to obtain the necessary m
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Page 660 and 661:
640million to $25 milliou per year.
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Page 662 and 663:
642Mr. Perito. Thank yoii. Mr. Chai
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Page 664 and 665:
644narcotic antagonist, and the oth
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Page 666 and 667:
646. Dr. Kramer. From what I have s
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Page 668 and 669:
—(348your money on, but methadone
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Page 670 and 671:
—650I know of no techinque in pri
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652Dr. Kramer. Yes, sir. As a matte
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Page 674 and 675:
:'654prison and who liave no—wlio
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65GDr. KT?A:\rEij. 1 suspect tliat
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658support some of the inethadone p
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'6660Dr. IvKAisrKK. 1 believe that
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662jrest that the Veterans' Adminis
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664opiates may be ingested in sever
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666(5) It suppresses the desire for
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668Many people have benefited from
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—G70Other researches which may di
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672synthetic painkillers, our commi
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074IV. A universal ban on legitimat
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..676iTlius we must look to educati
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678states, from Arnold Becker, publ
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680However, we must look at rehabil
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:682(a) The natural history of narc
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684was a heavy user. The decrease i
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686(13) Wallace. R. K. : Physiologi
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688TABLE 9.-USE OF "HARD LIQUOR" BE
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