Antibody Drug Conjugates for Cancer Therapy

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Naked antibodies did not workNaked <strong>Antibody</strong>Armed <strong>Antibody</strong>
Page 1 and 2: Antibody Drug Conjugates for Cancer
Page 3: Target Screening- Large scale mRNA-
Page 7: Bumps in the road from target ident
Page 10 and 11: Expression of TENB2/TMEFF1 in prost
Page 12 and 13: Levels of TenB2 mRNA in LuCAP77 > 2
Page 14 and 15: Comparison of anti-tenB2vc-MMAE in
Page 17 and 18: Mucin 16 (CA0772) ovarian cancer ta
Page 19 and 20: OvCAR3-luciferase intraperitoneal o
Page 21 and 22: Targeting broadly expressed antigen
Page 23 and 24: Lots of modelsEndogenous EDNBR expr
Page 25 and 26: Expression levels in tumor models a
Page 27 and 28: Some targets remain effective at ve
Page 29 and 30: Stability impacts SafetyTwo types o
Page 31 and 32: Strategies to Control Stoichiometry
Page 33 and 34: TDC is Better Tolerated than ADC by
Page 35 and 36: In vivo efficacy of an antibody arm

Antibody Drug Conjugates for Cancer Therapy

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