Antibody Drug Conjugates for Cancer Therapy
Antibody Drug Conjugates for Cancer Therapy
Antibody Drug Conjugates for Cancer Therapy
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Targeting broadly expressed antigens with armed antibodies can be dangerousExpression of CD44 mRNA in human tissuesnormal skin“At the highest dose levelachieved in this study (140mg/m2), one patient developedtoxic epidermal necrolysis aftertwo infusions and died. Massiveapoptosis of skin keratinocyteshad occurred”