Antibody Drug Conjugates for Cancer Therapy
Antibody Drug Conjugates for Cancer Therapy
Antibody Drug Conjugates for Cancer Therapy
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Antibodies armed with auristatinsANTIBODYDRUGMaleimidocaproylvalinecitrullinePABA MMAEMAbSONOONHOHNproteolysisONHOONOHNO“Ab-VC-MMAE”NO CH 3ONH ONOC H 3 O HON HN H 2* * **Seattle Genetics***Denotes possible sites of drug conjugation* *