<strong>Jeffrey</strong> N. <strong>Joyce</strong>, Ph.D. December 20<strong>12</strong><strong>University</strong> <strong>of</strong> Pennsylvania School <strong>of</strong> <strong>Medicine</strong>Tourette Syndrome Association (7/1/90 - 6/30/91), Developmental Plasticity <strong>of</strong> BasalGanglia Dopamine Systems,Total Direct Costs: $25,000National Institute <strong>of</strong> Mental Health (10/1/90 - 9/30/91), Dopamine Denervation <strong>and</strong>Receptor Subtype Regulation (F32 MH09888), Total Direct Costs: $28,000Current Postion: Associate Pr<strong>of</strong>essor <strong>of</strong> Psychology, Indiana <strong>University</strong>, Indianapolis, INAngela Murray, Ph.D., 1990 Royal College <strong>of</strong> Surgeons, Dublin, Irel<strong>and</strong>1990-1992 Postdoctoral Fellow (J.N. <strong>Joyce</strong>, Faculty Supervisor)Support:National Parkinson Foundation, Inc. (7/01/91 - 6/30/92), Dopamine Receptors inParkinson's <strong>and</strong> Alzheimer's Disease, Total Direct Costs: $40,000.Current Postion: Intellecutal Patents Advisor, Dublin, Irel<strong>and</strong>Lise Rioux, Ph.D., 1991 Laval Univeristy, Quebec, Canada1991- 1994 Postdoctoral Fellow (J.N. <strong>Joyce</strong>, Faculty Supervisor)Support:Fonds De La Recherche En Sante Du Quebec (7/01/91 - 3/30/94), Temporal Correlation<strong>of</strong> mRNA Coding for dopamine Receptors in Different Striatal Compartments as Relatedto Maturation <strong>of</strong> Dopamine Afferents, Total Direct Costs: $53,000NIB. (4/01/94 - 3/30/95), Substance P Receptors in Parkinson's <strong>and</strong> Alzheimer's Disease,Total Direct Costs: $30,000.Current Postion: Investigator, Dept Neurobiol & Anat, Drexel <strong>University</strong> Medical Center,Philadelphia, PAAdvanced Trainees:Eugenia Gurevich,Ph.D., 1985 Moscow State <strong>University</strong>, Russia1991-1995 Postdoctoral Fellow (J.N. <strong>Joyce</strong>, Faculty Supervisor)1995-2001 Scientist, Thomas H. Christopher Center for Parkinson's Disease ResearchCurrent Postion: Associate Pr<strong>of</strong>essor, Department <strong>of</strong> Pharmacology, V<strong>and</strong>erbilt<strong>University</strong> Medical Center, Nashville, TNInna Kruman, Ph.D., 1983 Moscow State <strong>University</strong>, Russia2001-2006 Staff Scientist, Thomas H. Christopher Center for Parkinson's DiseaseResearchCurent Position: Associate Pr<strong>of</strong>essor, Department <strong>of</strong> Neuropsychiatry, Garrison Instituteon Aging, Texas Tech <strong>University</strong> Health Sciences CenterThesis Supervision:8
<strong>Jeffrey</strong> N. <strong>Joyce</strong>, Ph.D. December 20<strong>12</strong>Sara Goldsmith: "Limbic dopamine D2 receptors: Interspecies differences <strong>and</strong> alterations inschizophrenia," presented in fulfillment <strong>of</strong> Doctor <strong>of</strong> Philosophy degree, Department <strong>of</strong>Psychology, <strong>University</strong> <strong>of</strong> Illinois, Chicago, May 1993. (J.N. <strong>Joyce</strong>, Faculty Supervisor- U Penn)Paul Frohna: "The developmental plasticity <strong>of</strong> the dopamine systems: Effects <strong>of</strong> neonatal 6-hydroxydopamine lesions on the ontogenesis <strong>of</strong> the mesostriatal dopamine neurons <strong>and</strong> <strong>of</strong>striatal dopamine D1 <strong>and</strong> D2 receptors <strong>and</strong> mRNA," Department <strong>of</strong> Pharmacology, <strong>University</strong> <strong>of</strong>Pennsylvania School <strong>of</strong> <strong>Medicine</strong> (awarded, 1995).Steve Presgraves: “SHSY-5Y neuroblastoma cells a DA-phenotypic model system for studyingD3 receptor agonist neuroprotection against MPP+-induced cell death” Center for Molecular <strong>and</strong>Cellular Biology, Arizona State <strong>University</strong>, Tempe AZ (awarded, 2005).T.C. Der, M.S.: “Role <strong>of</strong> the serotonin system in modulating neurotoxicity <strong>of</strong> MPTP todopamine neurons”. Graduate Program in Biology, Arizona State <strong>University</strong>, Tempe AZ(Awarded, 2007).MEDICAL SCIENCE COMMUNICATIONS AND PRESENTRATIONSIn 2007 I moved into the positions with largely administrative responsibilities but remain activein the research community. I have provided over 65 invited lectures at national <strong>and</strong> internationalmeetings, universities <strong>and</strong> other public forums in the areas <strong>of</strong> neuroscience, neuropsychiatry <strong>and</strong>neurodegenerative disorders. I have published over <strong>11</strong>0 original papers, reviews <strong>and</strong> bookchapters on subjects related to the areas <strong>of</strong> neuroscience, neuropsychiatry <strong>and</strong>neurodegenerative disorders.PEER-REVIEWED PUBLICATIONS, INVITED REVIEWS, BOOK CHAPTERSBIBLIOGRAPHYIn Research Administration <strong>and</strong> Development<strong>Joyce</strong>, <strong>Jeffrey</strong> N. Regulatory compliance for research in an academic medical center.Compliance Today [Health Care Compliance Association monthly] Vol 13, No. <strong>12</strong>,Pages 29- 37, December 20<strong>11</strong>.Original Papers1. Wills J, Jones J, Haggerty T, Duka V, <strong>Joyce</strong> JN, Sidhu A. Elevated tauopathy <strong>and</strong> alphasynuclein pathology in postmortem Parkinson's disease brains with <strong>and</strong> withoutdementia.. Exp Neurol. 2010 Sep;225(1):210-82. Massa, S., Yang, T., Xie, Y., Shi, J. Bilgen, M. <strong>Joyce</strong>, J. Nehama, D. Rajadas, J., <strong>and</strong>Longo, F. Small Molecule BDNF Mimetics that Activate TrkB Signaling <strong>and</strong> PreventNeuronal Degeneration. J Clin Invest. 2010 May 3;<strong>12</strong>0(5):1774-85.3. Iarkov, A., Der, T.C., <strong>Joyce</strong>, J.N. Age-related differences in MK-801 induced behaviorsin D 3 receptor knock out mice. European Journal <strong>of</strong> Pharmacology, Volume 627, Issues1-3, 10 February 2010, Pages 177-184.4. Yarkov, A., Der, T.C., <strong>Joyce</strong>, J.N. Locomotor activity induced by MK-801 is enhanced in9
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