Boston - American Association for Thoracic Surgery

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89 TH ANNUAL MEETING MAY 9–MAY 13, 2009BOSTON, MASSACHUSETTSgrowth 37% (117/319), stable growth 31% (100/319), and improving growth 32%(102/319). Frequency counts for HC categories were: impaired growth 39% (126/319),stable growth 28% (88/319), and improving growth 33% (105/319). Presence of adefinite or suspected genetic syndrome (p = 0.04) was found to be a predictor ofimpaired growth for WT, but not HC. When growth z-scores were used as continuousoutcomes, the APOE ε2 allele was found to be predictive of lower z-scores for bothWT (p = 0.02) and HC (p = 0.03).CONCLUSION: Impaired growth for both WT and HC is common (both > 30%)in this cohort of children following infant cardiac surgery. Both the APOE ε2 alleleand the presence of a definite or suspected genetic syndrome were associated withimpaired WT growth velocity. The APOE ε2 allele was also associated with impairedgrowth velocity for HC. Persistent poor growth may have long-term implicationsfor the health of children with CHD.184
AMERICAN ASSOCIATION FOR THORACIC SURGERY48. Mechanical Mitral Valve Prostheses in Children Don’t DeserveTheir Ill ReputeRoland Henaine, Joseph Nloga, Fabrice Wautot, Jacques Robin,Jean-François L. Obadia, * Jean NinetCadiothoracique Surgery, Lyon, FranceInvited Discussant: Christopher A. CaldaroneOBJECTIVE: There is no doubt that in children with congenital mitral valve(MV) disease reconstructive surgery is the first choice. When repair is not possible,however, MV replacement is an alternative which could benefit from better evaluation.Few data exists in the literature and we here report the long-term MV replacementresults in the largest series ever published: 30 children
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Boston - American Association for Thoracic Surgery

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