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Boston - American Association for Thoracic Surgery

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89 TH ANNUAL MEETING MAY 9–MAY 13, 2009BOSTON, MASSACHUSETTSPatients with Heterogeneous Emphysema and UPLP †LVRSMedical TherapyPre-Op(n = 261)6 months(n = 224)24 months(n = 167)Pre-Op(n = 250)6 months(n = 183)24 months(n = 121)FEV1Mean ± SD(L)%pred0.7 ± 0.327%1.0 ± 0.437%*0.9 ± 0.336%*0.7 ± 0.227%0.7 ± 0.227%0.8 ± 0.327%RVMean ± SD(L)%pred4.9 ± 1.2226%3.4 ± 1158%*3.6 ± 1160%*5.0 ± 1.1227%5.0 ± 1.2224%5.0 ± 1.2217%6 min walk(feet)Mean ± SD 1166 ± 315 1351 ± 306* 1329 ± 356* 1121 ± 302 1171 ± 317 1142 ± 362Total score onSt George’sRespiratoryQuestionnaire ‡Mean ± SD 56 ± 13 39 ± 21* 42 ± 17* 57 ± 13 56 ± 14 57 ± 14Total USCDShortness ofBreath Score Mean ± SD 65 ± 19 41 ± 23* 46 ± 24* 66 ± 19 65 ± 20 67 ± 22*p ≤ .001 <strong>for</strong> paired analyses with Pre-Op scores (two tailed t tests) UPLP: upper lobe predominance,when both upper lobes have the highest HRCT scores in terms of parenchyma destruction.† Difference of 2 points in the HRCT, between the areas of at least 1 lung to define heterogeneity.‡ The St. George’s Respiratory Questionnaire is a 51 item questionnaire on the health-relatedquality of life with regard to respiratory symptoms. Total score ranges from 0 to 100, with lowerscores indicating better health related quality of life. The University of Cali<strong>for</strong>nia, San Diego (UCSD), Shortness of Breath Questionnaire is a 24 itemquestionnaire about dyspnea. The total score ranges from 0 to 120, with lower scores indicatingless shortness of breath.3:20 p.m. INTERMISSION – VISIT EXHIBITSExhibit Hall102

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