Core facilities at EMBL â an overview - Molmedrex Project

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Cluster generationPrepare DNAfragmentsLigate adaptersAttach single molecules to surfaceAmplify to form clusters100 µmRandom array of clusters~1,000 molecules per ~ 1 µm 2 cluster~180,000 clusters per tile~22 million clusters/lane=>~8 Gb/flow cell
MPS spaceKahvejian, Nat Biotech 2008
Page 1 and 2: Core facilities at EMBL -an overvie
Page 3: Research & Core Facilities at EMBLP
Page 6 and 7: Core Facilities at EMBL• Advanced
Page 8 and 9: Unlocking the genomeCelniker et al.
Page 10 and 11: GeneCore ServicesLiquid handling ro
Page 12 and 13: GeneCore ServicesComplete support &
Page 14 and 15: Regulation of ERα responsive genes
Page 16 and 17: EMBL Solexas• ~180 million reads
Page 20 and 21: Applications at EMBL• Whole-genom
Page 22 and 23: Challenges• ChIP-Seq and RNA-Seq
Page 25 and 26: AcknowledgementRichard CarmoucheJü

Core facilities at EMBL â an overview - Molmedrex Project

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Core facilities at EMBL â an overview - Molmedrex Project