Protein Engineering Protocols - Mycobacteriology research center
Protein Engineering Protocols - Mycobacteriology research center Protein Engineering Protocols - Mycobacteriology research center
ContributorsKATJA M. ARNDT • Institut für Biologie III, Universität Freiburg, Freiburg,GermanyJAMIE M. BACHER • The Skaggs Institute for Chemical Biology, The ScrippsResearch Institute, La Jolla, CAPETER L. BERGQUIST • Biotechnology Research Institute, Macquarie University,Sydney, NSW, Australia; Department of Molecular Medicine and Pathology,Auckland University Medical School, Auckland, New ZealandLUKE H. BRADLEY • Department of Chemistry, Princeton University,Princeton, NJFRANÇOIS-XAVIER CAMPBELL-VALOIS • Département de Biochimie, Universitéde Montréal, Montréal, Québec, CanadaMICHEL DENAULT • Department of Quantitative Methods, HEC Montréal,Montréal, Québec, CanadaANDREW D. ELLINGTON • Institute for Cellular and Molecular Biologyand Department of Biochemistry, University of Texas, Austin, TXBIRTE K. FELD • Department of Chemistry and the Institute for Genomicsand Bioinformatics, University of California, Irvine, CAPETER FRIEDHOFF • Institut für Biochemie, Justus-Liebig-Universität,Giessen, GermanySATOSHI FUJITA • Department of Chemistry and Biotechnology, Schoolof Engineering, The University of Tokyo, Hongo, Tokyo, Japan; ResearchInstitute for Cell Engineering, National Institute of Advanced IndustrialScience and Technology (AIST), Tokyo, JapanFARID J. GHADESSY • MRC Laboratory of Molecular Biology, Cambridge,United Kingdom; Department of Oncology, University College MedicalSchool, London, United KingdomMORELAND D. GIBBS • Biotechnology Research Institute, Macquarie University,Sydney, NSW, AustraliaMICHAEL H. HECHT • Department of Chemistry, Princeton University,Princeton, NJJOCHEN HECKY • Institut für Biology III, Universität Freiburg, Freiburg,GermanyPHILIPP HOLLIGER • MRC Laboratory of Molecular Biology, Cambridge,United Kingdomix
x ContributorsMITSUHIKO IKURA • Division of Molecular and Structural Biology, OntarioCancer Institute and Department of Medical Biophysics, Universityof Toronto, Toronto, Ontario, CanadaAKIKO KOIDE • Department of Biochemistry and Molecular Biology,The University of Chicago, Chicago, ILSHOHEI KOIDE • Department of Biochemistry and Molecular Biology,The University of Chicago, Chicago, ILHIDETOSHI KONO • Computational Biology Group, Neutron Science ResearchCenter, Quantum Beam Science Directorate, Japan Atomic EnergyAgency, Kyoto, JapanJODY M. MASON • Institut für Biologie III, Universität Freiburg, Freiburg,GermanySTEPHEN W. MICHNICK • Département de Biochimie, Université de Montréal,Montréal, Québec, CanadaKRISTIAN M. MÜLLER • Institut für Biologie III, Universität Freiburg,Freiburg, GermanyATSUSHI MIYAWAKI • Laboratory for Cell Function and Dynamics, AdvancedTechnology Development Center, Brain Science Institute, RIKEN, WakoCity, Saitama, JapanWATARU NOMURA • Institute for Chemical Research, Kyoto University, Uji,Kyoto, JapanJOELLE N. PELLETIER • Département de Chimie, Université de Montréal,Montréal, Québec, CanadaALFRED PINGOUD • Institut für Biochemie, Justus-Liebig-Universität,Giessen, GermanyJEFFERY G. SAVEN • Makineni Theoretical Laboratories, Departmentof Chemistry, University of Pennsylvania, Philadelphia, PAASAKO SAWANO • Laboratory for Cell Function and Dynamics, AdvancedTechnology Development Center, Brain Science Institute, RIKEN, WakoCity, Saitama, Japan; Brain Science Research Division, Brain Scienceand Life Technology Research Foundation, Itabashi, Tokyo, JapanSACHDEV S. SIDHU • Department of Protein Engineering, Genentech Inc.,South San Francisco, CASABINE C. STEBEL • Institut für Biologie III, Universität Freiburg, Freiburg,GermanyYUKIO SUGIURA • Faculty of Pharmaceutical Sciences, Doshisha Women'sUniversity, Koudo, Kyotanabe, Japan
- Page 1 and 2: METHODS IN MOLECULAR BIOLOGY 352Pr
- Page 4 and 5: M E T H O D S I N M O L E C U L A R
- Page 6 and 7: PrefaceProtein engineering is a fas
- Page 8 and 9: ContentsPreface ...................
- Page 12: Contributors xiKAZUNARI TAIRA • D
- Page 16 and 17: 1Combinatorial Protein Design Strat
- Page 18 and 19: Combinatorial Protein Design Strate
- Page 20 and 21: Combinatorial Protein Design Strate
- Page 22 and 23: Combinatorial Protein Design Strate
- Page 24 and 25: Combinatorial Protein Design Strate
- Page 26 and 27: Combinatorial Protein Design Strate
- Page 28 and 29: Combinatorial Protein Design Strate
- Page 30 and 31: Combinatorial Protein Design Strate
- Page 32 and 33: Combinatorial Protein Design Strate
- Page 34 and 35: Combinatorial Protein Design Strate
- Page 36 and 37: 2Global Incorporation of Unnatural
- Page 38 and 39: Incorporation of Unnatural Amino Ac
- Page 40 and 41: Incorporation of Unnatural Amino Ac
- Page 42 and 43: Incorporation of Unnatural Amino Ac
- Page 44 and 45: Incorporation of Unnatural Amino Ac
- Page 46 and 47: Incorporation of Unnatural Amino Ac
- Page 48 and 49: 3Considerations in the Design and O
- Page 50 and 51: Design of Coiled Coil Structures 37
- Page 52 and 53: Design of Coiled Coil Structures 39
- Page 54 and 55: Design of Coiled Coil Structures 41
- Page 56 and 57: Design of Coiled Coil Structures 43
- Page 58 and 59: Design of Coiled Coil Structures 45
x ContributorsMITSUHIKO IKURA • Division of Molecular and Structural Biology, OntarioCancer Institute and Department of Medical Biophysics, Universityof Toronto, Toronto, Ontario, CanadaAKIKO KOIDE • Department of Biochemistry and Molecular Biology,The University of Chicago, Chicago, ILSHOHEI KOIDE • Department of Biochemistry and Molecular Biology,The University of Chicago, Chicago, ILHIDETOSHI KONO • Computational Biology Group, Neutron Science ResearchCenter, Quantum Beam Science Directorate, Japan Atomic EnergyAgency, Kyoto, JapanJODY M. MASON • Institut für Biologie III, Universität Freiburg, Freiburg,GermanySTEPHEN W. MICHNICK • Département de Biochimie, Université de Montréal,Montréal, Québec, CanadaKRISTIAN M. MÜLLER • Institut für Biologie III, Universität Freiburg,Freiburg, GermanyATSUSHI MIYAWAKI • Laboratory for Cell Function and Dynamics, AdvancedTechnology Development Center, Brain Science Institute, RIKEN, WakoCity, Saitama, JapanWATARU NOMURA • Institute for Chemical Research, Kyoto University, Uji,Kyoto, JapanJOELLE N. PELLETIER • Département de Chimie, Université de Montréal,Montréal, Québec, CanadaALFRED PINGOUD • Institut für Biochemie, Justus-Liebig-Universität,Giessen, GermanyJEFFERY G. SAVEN • Makineni Theoretical Laboratories, Departmentof Chemistry, University of Pennsylvania, Philadelphia, PAASAKO SAWANO • Laboratory for Cell Function and Dynamics, AdvancedTechnology Development Center, Brain Science Institute, RIKEN, WakoCity, Saitama, Japan; Brain Science Research Division, Brain Scienceand Life Technology Research Foundation, Itabashi, Tokyo, JapanSACHDEV S. SIDHU • Department of <strong>Protein</strong> <strong>Engineering</strong>, Genentech Inc.,South San Francisco, CASABINE C. STEBEL • Institut für Biologie III, Universität Freiburg, Freiburg,GermanyYUKIO SUGIURA • Faculty of Pharmaceutical Sciences, Doshisha Women'sUniversity, Koudo, Kyotanabe, Japan