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Diabetes and Exercise: Why Exercise Works When Insulin Does Not

Diabetes and Exercise: Why Exercise Works When Insulin Does Not

Diabetes and Exercise: Why Exercise Works When Insulin Does Not

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Metformin- Single most prescribed oral antidiabetic drug in the U.S.- Cellular mechanism of action is unclear* Suppresses hepatic glucose production* Increases muscle glucose uptake* Inhibits Complex 1 of Respiratory Chain(Owen, Biochem J, 2000 <strong>and</strong> El-Mir, JBC, 2000)

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