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<strong>2009</strong> <strong>Review</strong>


2<br />

“Alone<br />

we can<br />

do so<br />

little;<br />

toge<strong>the</strong>r<br />

we can<br />

do so<br />

much.”<br />

– Helen Keller<br />

Dear Friends,<br />

As I reflect upon <strong>2009</strong>, I am reminded <strong>of</strong> Helen Keller’s simple, yet pr<strong>of</strong>ound<br />

observation: “Alone we can do so little; toge<strong>the</strong>r, we can do so much.” Indeed, everything<br />

we accomplish at <strong>the</strong> <strong>University</strong> <strong>of</strong> Arizona <strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong> is a<br />

result <strong>of</strong> individuals working toge<strong>the</strong>r to make <strong>the</strong> world a better place for children.<br />

You will see this idea woven into <strong>the</strong> articles throughout this annual review.<br />

As UMC and <strong>the</strong> UA <strong>Steele</strong> <strong>Center</strong> work toge<strong>the</strong>r to complete Diamond Children’s<br />

Medical <strong>Center</strong>, I am inspired by what this momentous accomplishment signifies.<br />

Diamond Children’s will provide compassionate, expert and family-centered care by<br />

our world-class physicians, nurses, specialists and residents—in a beautiful, state-<strong>of</strong><strong>the</strong>-art<br />

facility designed for children and <strong>the</strong>ir families. Hope is on <strong>the</strong> horizon!<br />

What’s more, because Diamond Children’s is connected to <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>, our<br />

young patients benefit from being treated by physician-scientists who also are<br />

researching <strong>the</strong> causes <strong>of</strong>, and developing new treatments and cures for, children’s<br />

illnesses. We ardently strive to improve clinical care through translational, or “bench<br />

to bedside” research. This means translating our basic-science research discoveries<br />

(bench) to practical, clinical applications that benefit <strong>the</strong> child (bedside).<br />

For example, our Dorrance Fellow in Pediatric Gastroenterology and Nutrition—<br />

Rajalakshmy Ramalingam—has made a discovery that may bring new understanding<br />

to what causes IBD (inflammatory bowel disease). Collin LaCasse, our Courtney Page<br />

Zillman Fellow, is working with <strong>the</strong> pediatric oncology research team to advance <strong>the</strong><br />

CRCL cancer vaccine developed here and now heading toward clinical trials.<br />

It is no coincidence that <strong>the</strong> most remarkable advances in children’s health over <strong>the</strong><br />

past 10 years were achieved by academically-based children’s medical centers. In fact,<br />

all top-ranked children’s hospitals are connected to academic medical centers, such<br />

as Children’s Hospital Boston (Harvard) and Children’s Hospital <strong>of</strong> Philadelphia<br />

(<strong>University</strong> <strong>of</strong> Pennsylvania). By working toge<strong>the</strong>r, I know Diamond Children’s and<br />

<strong>the</strong> <strong>Steele</strong> <strong>Center</strong> soon will be a top-ranked academic children’s medical center as well.<br />

No child should suffer from cancer, diabetes, gastrointestinal disorders, heart problems<br />

or <strong>the</strong> myriad o<strong>the</strong>r pediatrics illnesses. But, when a child is sick from illness or<br />

injury, we are here to provide exceptional care. Because <strong>of</strong> friends and supporters<br />

like you, <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> continues to improve children’s health through our mission<br />

to teach, to heal and to discover. Toge<strong>the</strong>r, we are making <strong>the</strong> world a healthier place<br />

for children.<br />

With gratitude,<br />

Fayez K. Ghishan, MD<br />

Horace W. <strong>Steele</strong> Endowed Chair in Pediatric <strong>Research</strong><br />

Director, <strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong><br />

Pr<strong>of</strong>essor and Head, Department <strong>of</strong> Pediatrics<br />

The <strong>University</strong> <strong>of</strong> Arizona College <strong>of</strong> Medicine<br />

<strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong> <strong>Review</strong>, February 2010. Issue 16. <strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong> <strong>Review</strong> is published annually<br />

by <strong>the</strong> <strong>University</strong> <strong>of</strong> Arizona, <strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong>, Department <strong>of</strong> Pediatrics, PO Box 245073, Tucson, AZ 85724-5073.<br />

<strong>Steele</strong> <strong>Center</strong> Receives Grant to Study <strong>the</strong> Role <strong>of</strong><br />

Calcium and Klotho Gene in IBD-related Bone Loss<br />

he <strong>Steele</strong> Children’s <strong>Research</strong><br />

T<strong>Center</strong> received an NIH<br />

American Recovery and<br />

Reinvestment Act grant for<br />

$605,250 that expands ongoing<br />

research conducted by Dr. Ghishan<br />

and his research team. The twoyear<br />

grant, titled “Development <strong>of</strong><br />

Intestinal Transport <strong>of</strong> Calcium<br />

and Phosphate,” investigates<br />

ano<strong>the</strong>r key component <strong>of</strong> bone<br />

health—calcium—and how<br />

inflammation affects calcium<br />

absorption by <strong>the</strong> gut and <strong>the</strong><br />

kidneys.<br />

“Our previous research focused<br />

on phosphate balance. This study<br />

will focus on calcium absorption.<br />

It takes both to develop strong<br />

bones,” says Dr. Ghishan, principal<br />

investigator <strong>of</strong> <strong>the</strong> study.<br />

In children and young adults<br />

suffering from inflammatory bowel<br />

diseases (IBD), bone density <strong>of</strong>ten<br />

is affected, resulting in osteopenia<br />

or osteoporosis. This decrease<br />

results in a higher risk <strong>of</strong> bone<br />

fractures later in life.<br />

“Although we have long suspected<br />

that calcium deficiency may be an<br />

underlying factor in IBD-related<br />

bone loss, <strong>the</strong> mechanisms by<br />

which <strong>the</strong> calcium absorptive and<br />

re-absorptive mechanisms are<br />

disrupted by chronic intestinal<br />

inflammation are still unknown,”<br />

says Pawel Kiela, DVM, PhD,<br />

co-investigator <strong>of</strong> <strong>the</strong> study.<br />

“So, it’s vital to understand<br />

how inflammation affects <strong>the</strong><br />

key players involved in <strong>the</strong><br />

maintenance <strong>of</strong> calcium balance.”<br />

One mechanism <strong>the</strong> research<br />

team will explore is <strong>the</strong> role<br />

<strong>the</strong> “Klotho” gene plays in<br />

how calcium is transported and<br />

absorbed by <strong>the</strong> kidneys. Previous<br />

research established that when<br />

Klotho is down-regulated, signs <strong>of</strong><br />

premature aging appear, including<br />

osteoporosis.<br />

Recently, <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> team<br />

discovered that Klotho is downregulated<br />

in acute and chronic<br />

colitis. “This is a fascinating<br />

connection,” Dr. Kiela says. “We’re<br />

now hypo<strong>the</strong>sizing that when Klotho<br />

is down-regulated, it negatively<br />

affects renal calcium reabsorption<br />

which, along with o<strong>the</strong>r metabolic<br />

complications, contributes to colitisassociated<br />

calcium imbalance and <strong>the</strong><br />

resulting bone loss.”<br />

“The more we understand <strong>the</strong><br />

mechanisms involved in calcium<br />

and phosphate absorption, <strong>the</strong> better<br />

chance we’ll have <strong>of</strong> developing new<br />

<strong>the</strong>rapies to help children and adults<br />

suffering from IBD-related bone<br />

loss,” says Dr. Ghishan.<br />

3


4<br />

A Legacy <strong>of</strong> Giving: The Arizona Elks Major Projects<br />

n 1992, <strong>the</strong> Arizona Elks Major Projects began <strong>the</strong>ir incredible commitment to <strong>the</strong> work <strong>of</strong> <strong>the</strong> <strong>Steele</strong> Children’s<br />

I<strong>Research</strong> <strong>Center</strong>. Raising between $200,000 and $300,000 each year, <strong>the</strong> Elks have made a significant difference<br />

in children’s health. Here are highlights <strong>of</strong> Elks-supported projects through <strong>the</strong> years:<br />

Arizona Elks Laboratories for<br />

Transplantation <strong>Research</strong><br />

Amount raised: $275,000<br />

One <strong>of</strong> <strong>the</strong> first projects <strong>the</strong> Elks<br />

undertook was supporting <strong>the</strong><br />

building <strong>of</strong> two research labs<br />

on <strong>the</strong> sixth floor <strong>of</strong> <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong>. These labs currently house<br />

researchers who specialize in<br />

gastroenterology and nutrition.<br />

Seed <strong>Research</strong> Awards<br />

Amount raised: $1.2 million<br />

Seed grants allow investigators to<br />

“prime <strong>the</strong> pump” with preliminary<br />

data, which will make <strong>the</strong>ir<br />

research projects more attractive to<br />

state and federal funding agencies.<br />

Education<br />

Amount raised: $50,000<br />

The education funds assisted<br />

with developing <strong>the</strong> first Pediatric<br />

Integrative Medicine Conference,<br />

and supported <strong>the</strong> “Morning for<br />

Children’s Health” workshops for<br />

parents.<br />

Arizona Elks Clinic for<br />

Children and Young Adults<br />

Amount raised: $390,000<br />

In 2001, <strong>the</strong> Arizona Elks<br />

celebrated <strong>the</strong> grand re-opening <strong>of</strong><br />

<strong>the</strong> newly named “Arizona Elks<br />

Clinic for Children and Young<br />

Adults.” The renovated clinic now<br />

includes separate waiting areas for<br />

sick children and well children,<br />

and more efficient space for<br />

doctors, nurses and staff.<br />

Core Support<br />

Amount raised: $255,000<br />

Core support funds are used<br />

to improve facilities and repair<br />

research equipment throughout <strong>the</strong><br />

<strong>Steele</strong> <strong>Center</strong>.<br />

Marvin Lewis Pediatric<br />

Teaching <strong>Center</strong><br />

Amount raised: $130,000<br />

Marvin Lewis, a past Grand<br />

Exalted Ruler, was passionate<br />

about education and helping<br />

children. Funds were used to<br />

renovate <strong>the</strong> pediatric residency<br />

<strong>of</strong>fices and create a conference<br />

room. Upon completion, <strong>the</strong> space<br />

was named <strong>the</strong> “Marvin Lewis<br />

Pediatric Teaching <strong>Center</strong>.”<br />

About this year’s front<br />

cover: Giovanna Manzo, 4,<br />

and her grandfa<strong>the</strong>r, Tom<br />

Welch, member <strong>of</strong> Chandler<br />

Elks Lodge, No. 2429.<br />

Giovanna is currently a<br />

patient <strong>of</strong> <strong>Steele</strong> <strong>Center</strong><br />

pediatric allergist/<br />

immunologist, Michael<br />

Daines, MD, and pediatric<br />

pulmonologist,<br />

Cori Daines, MD.<br />

Amy and John Manzo: Grateful for <strong>the</strong> Arizona Elks<br />

and <strong>Steele</strong> <strong>Center</strong> Physicians<br />

ur second daughter, Giovanna, was born on September 1,<br />

O2005. She seemed to be healthy during her first year <strong>of</strong> life.<br />

After her 1-year-old checkup and vaccinations, we realized<br />

something was seriously wrong. That was <strong>the</strong> beginning <strong>of</strong><br />

Giovanna’s battle with illness after illness, infection after<br />

infection. We were seen by several specialists in <strong>the</strong> Phoenix<br />

area. Over <strong>the</strong> past three years, we’ve traveled to Lucile Packard<br />

Children’s Hospital at Stanford in California, The Mayo Clinic<br />

in Minnesota, and The Children’s Hospital in Colorado. We<br />

watched Giovanna become extremely ill and suffer respiratory<br />

and cardiac arrest. She has been hospitalized eight times.<br />

Most recently, Linda Lewandowski, with <strong>the</strong> Arizona Elks Major Projects, arranged for<br />

Giovanna to be examined by <strong>Steele</strong> <strong>Center</strong> physicians Drs. Michael and Cori Daines.<br />

The “Great Daines,” as we call <strong>the</strong>m, reviewed Giovanna’s medical records and helped us<br />

understand her illness and treatment. Giovanna suffers from an unknown chronic disease that<br />

attacks her sinuses and lungs. Dr. Cori Daines placed Giovanna’s illness in an “unknown<br />

category” with “primary ciliary dyskinesia” and “cystic fibrosis” symptoms.<br />

We are so grateful to <strong>the</strong> Arizona Elks Major Projects and Drs. Michael and Cori Daines for<br />

<strong>the</strong> treatment, support and encouragement <strong>the</strong>y’ve given us in caring for our daughter!<br />

—Amy and John Manzo, members <strong>of</strong> Chandler Elks Lodge, No. 2429<br />

Arizona Elks Endowed Chair<br />

in Neonatology <strong>Research</strong><br />

Amount raised: $1.8 million (Goal: $2.5 million)<br />

In 2003, <strong>the</strong> Arizona Elks committed to creating <strong>the</strong><br />

“Arizona Elks Endowed Chair in Neonatology <strong>Research</strong>.”<br />

An endowed chair generates income that lasts forever.<br />

Every year, a portion <strong>of</strong> <strong>the</strong> interest is available to <strong>the</strong><br />

Chair to support research and provide seed funding to<br />

promising young investigators interested in neonatal<br />

research.<br />

Toys, Blankets, Beanies and Booties<br />

Amount raised: Priceless<br />

There is simply no price that can be assigned to <strong>the</strong><br />

hundreds <strong>of</strong> blankets, beanies and booties that have been<br />

knitted by <strong>the</strong> Elks for <strong>the</strong> premature babies at <strong>University</strong><br />

Medical <strong>Center</strong>. Or <strong>the</strong> thousands <strong>of</strong> donated toys and<br />

blankets that have brought a smile to a sick child’s face.<br />

We are immensely grateful for <strong>the</strong>se priceless gifts from<br />

<strong>the</strong> Arizona Elks lodges throughout Arizona!<br />

5


6<br />

Dorrance Fellow Update:<br />

Rajalakshmy Ramalingam<br />

hanks to <strong>the</strong> Dorrance<br />

TEndowed Fellowship in<br />

Pediatric Gastroenterology and<br />

Nutrition, I’m investigating <strong>the</strong><br />

immunological mechanisms that<br />

may contribute to <strong>the</strong> development<br />

<strong>of</strong> Inflammatory Bowel Disease<br />

(IBD), a painful gastrointestinal<br />

disorder and autoimmune disease<br />

affecting millions <strong>of</strong> Americans,<br />

I<br />

where nearly one in four are<br />

under 20 years old.<br />

Our research team has developed<br />

a mouse model with a specific<br />

gene (tumor growth factor<br />

receptor) deleted from a particular<br />

type <strong>of</strong> immune cell to study its<br />

contribution to <strong>the</strong> cause <strong>of</strong> IBD.<br />

Exceeding our expectations, <strong>the</strong>se<br />

Courtney Page Zillman Fellow<br />

Update: Collin LaCasse<br />

am honored to be <strong>the</strong> sixth<br />

Tee Up For Tots Courtney<br />

Page Zillman Fellow.<br />

A decade ago, Dr. Emmanuel<br />

Katsanis developed a new cancer<br />

vaccine, which takes a patient’s<br />

own tumor and isolates <strong>the</strong><br />

components <strong>of</strong> that tumor that<br />

are most likely to initiate a strong<br />

immune response. It now is<br />

nearing human clinical trials in <strong>the</strong><br />

United States.<br />

Unfortunately, <strong>the</strong>re is an obstacle<br />

that prohibits cancer vaccines<br />

from functioning properly.<br />

This obstacle is cancer-induced<br />

immunosuppression. Many cancer<br />

cells promote <strong>the</strong>ir own survival by<br />

secreting chemicals that virtually<br />

shut down <strong>the</strong> immune response<br />

in and around <strong>the</strong> tumor. They<br />

do this in part by hijacking<br />

immunosuppressive cells whose<br />

purpose in healthy individuals is<br />

to suppress immune cells in order<br />

to prevent over-active immune<br />

responses and autoimmunity.<br />

In cancer patients, <strong>the</strong>se hijacked<br />

immunosuppressive cells, instead <strong>of</strong><br />

protecting against autoimmunity,<br />

surround <strong>the</strong> tumor, preventing <strong>the</strong><br />

immune system from identifying<br />

and destroying <strong>the</strong> cancer. These<br />

genetically modified mice develop<br />

systemic autoimmune disease.<br />

This exciting observation now has<br />

broadened our scope <strong>of</strong> research.<br />

There are approximately 150<br />

different autoimmune diseases,<br />

including IBD. <strong>Research</strong> involved<br />

in understanding <strong>the</strong> mechanisms<br />

<strong>of</strong> <strong>the</strong>se diseases is essential<br />

for developing new methods to<br />

improve diagnosis and treatment.<br />

Because <strong>of</strong> <strong>the</strong> Dorrance Family<br />

Foundation and <strong>the</strong> leadership<br />

<strong>of</strong> Drs. Ghishan and Kiela, our<br />

laboratory not only has survived<br />

during this difficult economic time,<br />

but we have made major scientific<br />

advancements. The Dorrance<br />

Fellowship could not have come at<br />

a better time, with <strong>the</strong> competition<br />

for funding increasing every day.<br />

I am extremely grateful to <strong>the</strong><br />

Dorrance family and Drs. Ghishan<br />

and Kiela for giving me <strong>the</strong><br />

opportunity to pursue my PhD<br />

in immunobiology at <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong>. Thank you!<br />

immunosuppressive cells must be<br />

targeted and destroyed. This is my<br />

primary research focus, and we<br />

have made great strides.<br />

I can’t wait for a day when<br />

our discoveries in <strong>the</strong> lab are<br />

implemented in <strong>the</strong> clinic,<br />

contributing to <strong>the</strong> eradication <strong>of</strong><br />

pediatric cancers! I am grateful for<br />

Tee Up For Tots, whose support<br />

makes this research possible.<br />

A Loving Memorial for Beloved Son:<br />

The ‘Kick Cancer for Stephen Foundation’<br />

tephen Placencia was a quiet<br />

S young man with friendly blue<br />

eyes and a warm smile. Humble<br />

in spirit and naturally athletic,<br />

Stephen excelled at soccer. As<br />

a member <strong>of</strong> <strong>the</strong> Cienega High<br />

School varsity soccer team, he<br />

was <strong>the</strong> highest scorer during his<br />

sophomore year. Stephen also<br />

enjoyed riding dirt bikes and<br />

spending time with his friends and<br />

family.<br />

In 2005, when Stephen was 14, he<br />

was diagnosed with a rare form<br />

<strong>of</strong> liver cancer—fibrolamellar<br />

hepatocellular carcinoma. After<br />

many surgeries, radiation and<br />

chemo<strong>the</strong>rapy treatments, Stephen<br />

passed away on January 14, 2008.<br />

He was only 17. “Through it all,”<br />

says Stephen’s mom, Francie,<br />

“he never questioned why he got<br />

cancer. He accepted it with grace<br />

and just went through it. Stephen<br />

had an amazing spirit, and we<br />

loved him beyond words.”<br />

While hospitalized, Stephen<br />

noticed few activities available<br />

for teenagers. “When teens are<br />

hospitalized, <strong>the</strong>ir stay is more<br />

bearable if <strong>the</strong>re are fun things for<br />

<strong>the</strong>m to do, such as playing video<br />

games or <strong>the</strong> Wii, or watching<br />

movies that appeal to <strong>the</strong>m,”<br />

says Francie. “Stephen wanted to<br />

improve <strong>the</strong> experience <strong>of</strong> teens<br />

who were hospitalized.”<br />

About a year after Stephen’s<br />

death, Francie and her husband,<br />

Steve, created <strong>the</strong> Kick Cancer<br />

for Stephen Foundation. The<br />

foundation’s goals are to provide<br />

funding for pediatric cancer<br />

research at <strong>the</strong> <strong>Steele</strong> Children’s<br />

<strong>Research</strong> <strong>Center</strong>, provide activities<br />

for hospitalized teenagers and<br />

provide resources to parents and<br />

family members who have a child<br />

with cancer or have lost a child to<br />

cancer.<br />

So far, <strong>the</strong> foundation has donated<br />

flat-screen TVs, gaming systems,<br />

X-boxes and Playstations, Wii<br />

systems, Guitar Hero, games, movies,<br />

Best Buy gift cards and countless<br />

snacks and drinks to <strong>the</strong> infusion<br />

clinic within <strong>the</strong> Elks Clinic for<br />

Children and Young Adults and to<br />

<strong>the</strong> pediatric wards at <strong>University</strong><br />

Medical <strong>Center</strong>.<br />

“The children get so excited when<br />

<strong>the</strong>y see <strong>the</strong> games <strong>the</strong>y can play<br />

while receiving treatment,” says Laura<br />

DiStefano, one <strong>of</strong> <strong>the</strong> nurses who<br />

treated Stephen at <strong>the</strong> infusion clinic.<br />

“The games help <strong>the</strong>m endure <strong>the</strong>ir<br />

treatments. We are inspired by Steve<br />

and Francie’s commitment to help<br />

<strong>the</strong>se kids and families.”<br />

“This has been a meaningful way for<br />

us to keep Stephen’s memory alive,<br />

and I see something positive coming<br />

out <strong>of</strong> this,” says Francie. “We’re<br />

doing it in Stephen’s honor, because<br />

he touched so many lives and we<br />

want his spirit to be carried on.”<br />

If you would like to contribute to<br />

Kick Cancer for Stephen, please<br />

visit: www.kickcancerforstephen.com.<br />

7


8<br />

Dr. Katsanis Named<br />

Leading Edge<br />

<strong>Research</strong>er at <strong>the</strong><br />

<strong>University</strong> <strong>of</strong> Arizona<br />

teele Children’s <strong>Research</strong> <strong>Center</strong> scientist and<br />

Spediatric oncologist Emmanuel Katsanis, MD,<br />

Pr<strong>of</strong>essor <strong>of</strong> Pediatrics and Chief <strong>of</strong> <strong>the</strong> Section <strong>of</strong><br />

Pediatric Hematology/Oncology was named one <strong>of</strong><br />

only five UA Leading Edge <strong>Research</strong>ers.<br />

Dr. Katsanis, who holds <strong>the</strong> prestigious Louise<br />

Thomas Endowed Chair in Pediatric Cancer<br />

<strong>Research</strong> at <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>, was honored at <strong>the</strong><br />

UA’s sixth annual Innovation Day celebration in<br />

March, which recognized research achievements <strong>of</strong><br />

students, faculty and staff. He was honored for his<br />

ground-breaking research in <strong>the</strong> development <strong>of</strong><br />

<strong>the</strong> novel cancer vaccine, CRCL, which is nearing<br />

human clinical trials.<br />

“We’re very happy for Dr. Katsanis,” said Dr.<br />

Ghishan. “His discovery and development <strong>of</strong> <strong>the</strong><br />

CRCL cancer vaccine will ultimately lead to novel<br />

treatments for patients with leukemia and o<strong>the</strong>r<br />

blood cancers, with <strong>the</strong> ultimate goal <strong>of</strong> saving<br />

lives. We are extremely proud <strong>of</strong> this pioneering<br />

researcher.”<br />

Dr. Ghishan<br />

Receives Prestigious<br />

Distinguished Alumnus<br />

Award for Achievement<br />

ongratulations to Dr. Ghishan, who received a<br />

Cprestigious Distinguished Alumnus Award for<br />

Achievement from <strong>the</strong> <strong>University</strong> <strong>of</strong> Iowa Carver<br />

College <strong>of</strong> Medicine. He was honored during a<br />

special awards luncheon ceremony in June.<br />

The Distinguished Alumni Award is <strong>the</strong> highest<br />

honor <strong>the</strong> college bestows upon its graduates,<br />

recognizing those who have transcended <strong>the</strong>ir<br />

fundamental roles as health-care providers, scientists<br />

and educators to become leaders in <strong>the</strong> advancement<br />

<strong>of</strong> medicine.<br />

Dr. Ghishan was honored with <strong>the</strong> Award for<br />

Achievement for his continued leadership in<br />

pediatric gastroenterology, which has advanced<br />

patient care, research and teaching. Internationally<br />

recognized for his research in pediatric<br />

gastroenterology and nutrition, Dr. Ghishan has<br />

authored more than 400 publications including<br />

original articles, editorials, abstracts, book reviews<br />

and chapters. His groundbreaking research has<br />

continuously been funded by <strong>the</strong> National Institutes<br />

<strong>of</strong> Health for <strong>the</strong> past 30 years.<br />

<strong>Steele</strong> <strong>Center</strong> <strong>Research</strong> Reveals Probiotics a Promising<br />

Treatment for Common Illness among Premature Babies<br />

teele Children’s <strong>Research</strong> <strong>Center</strong><br />

S<strong>Research</strong> Pr<strong>of</strong>essor Bohuslav<br />

Dvorak, PhD, and his research<br />

team have discovered that using<br />

probiotics (healthy live bacteria<br />

found in yogurt) is an effective way<br />

to reduce and prevent a common,<br />

yet devastating, disease that affects<br />

babies born prematurely.<br />

NEC (necrotizing enterocolitis)<br />

is a gastrointestinal disease <strong>of</strong><br />

<strong>the</strong> intestines that afflicts nearly<br />

10,000 premature babies every<br />

year. The exact cause <strong>of</strong> NEC is<br />

unknown, and <strong>the</strong> disease can be<br />

mild to severe. In severe cases, a<br />

child’s inflamed intestines may<br />

tear, causing bacteria to leak into<br />

<strong>the</strong> abdomen—potentially causing<br />

a life-threatening infection. Sadly,<br />

nearly 40 percent <strong>of</strong> babies with<br />

NEC will not survive.<br />

Using an experimental model<br />

<strong>of</strong> NEC, Dr. Dvorak and his<br />

team have shown that oral<br />

administration <strong>of</strong> probiotics is a<br />

promising strategy to prevent and<br />

treat NEC. “We have confirmed<br />

that <strong>the</strong> probiotic Bifidobacterium<br />

bifidum, when added to infant<br />

formula, significantly reduces <strong>the</strong><br />

incidence and severity <strong>of</strong> NEC,”<br />

says Dr. Dvorak. “This particular<br />

strain <strong>of</strong> probiotics reduces<br />

inflammation in <strong>the</strong> intestines and<br />

reinforces <strong>the</strong> intestinal barrier.”<br />

Now that Dr. Dvorak and his<br />

team have established <strong>the</strong> efficacy<br />

<strong>of</strong> Bifidobacterium bifidum, <strong>the</strong>y<br />

are exploring how probiotics<br />

protect against NEC at <strong>the</strong><br />

cellular and molecular levels, and<br />

what long-term consequences—if<br />

any—<strong>the</strong>y have on immune and<br />

gastrointestinal functions.<br />

Their study, “Bifidobacterium<br />

bifidum improves intestinal integrity<br />

in a rat model <strong>of</strong> necrotizing<br />

enterocolitis,” was published in<br />

<strong>the</strong> American Journal <strong>of</strong> Physiology:<br />

Gastrointestinal and Liver<br />

Physiology.<br />

9


10<br />

Grateful for our Volunteer Groups and Events<br />

D<br />

espite many economic challenges this year, <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> continues to receive support from<br />

many volunteer groups and special events. On behalf <strong>of</strong> our doctors, researchers, patients and staff,<br />

thank you to all <strong>of</strong> our volunteers! Your efforts make a difference in <strong>the</strong> lives <strong>of</strong> children.<br />

Arizona Elks Major Projects<br />

(AEMP)<br />

he 49 Elks<br />

lodges<br />

T<br />

across<br />

Arizona<br />

continue<br />

to work<br />

tirelessly to build <strong>the</strong> Arizona Elks<br />

Endowed Chair in Neonatology<br />

<strong>Research</strong>. This year, <strong>the</strong> Elks<br />

gave ano<strong>the</strong>r $250,000, bringing<br />

<strong>the</strong>ir total to more than $4<br />

million. Thanks to <strong>the</strong>ir support,<br />

Alan Bedrick, MD, holder <strong>of</strong> <strong>the</strong><br />

Chair, and his team in <strong>the</strong> NICU<br />

continue to help newborn babies,<br />

while researchers search for better<br />

ways to treat neonatal diseases.<br />

Fa<strong>the</strong>r’s Day Council Tucson<br />

our outstanding fa<strong>the</strong>rs were<br />

honored this year at <strong>the</strong> annual<br />

F<br />

Golf Classic and Fa<strong>the</strong>rs <strong>of</strong> <strong>the</strong><br />

Year Awards Gala. With <strong>the</strong><br />

support and<br />

dedication<br />

<strong>of</strong> Fa<strong>the</strong>r’s<br />

Day Council<br />

behind <strong>the</strong>m,<br />

<strong>the</strong> honorees<br />

raised more<br />

than $200,000 this year. Funds<br />

will support research and clinical<br />

care in type 1 diabetes, and help<br />

build <strong>the</strong> Fa<strong>the</strong>r’s Day Council<br />

Tucson Endowed Chair for Type<br />

1 Diabetes.<br />

Runway for <strong>Research</strong><br />

ore than 50 children–current<br />

cancer patients,<br />

M<br />

survivors and <strong>the</strong>ir<br />

siblings—showed<br />

<strong>of</strong>f <strong>the</strong> latest<br />

designs by<br />

students at The<br />

Art Institute <strong>of</strong><br />

Tucson. The<br />

Runway for <strong>Research</strong> fashion show<br />

drew an impressive crowd, filling<br />

<strong>the</strong> ballroom to capacity. Funds<br />

raised support pediatric cancer<br />

research.<br />

Tee Up For Tots<br />

T<br />

ee Up For<br />

Tots’ brigade<br />

<strong>of</strong> volunteers<br />

worked<br />

relentlessly for this year’s golf<br />

tournament, in memory <strong>of</strong> Courtney<br />

Page Zillman, who passed away<br />

from neuroblastoma when she<br />

was only 4. Proceeds support<br />

graduate student and pediatric<br />

cancer researcher Collin LaCasse,<br />

<strong>the</strong> TUFT Courtney Page Zillman<br />

Fellow.<br />

Women’s Active 20-30 Club <strong>of</strong><br />

Sou<strong>the</strong>rn Arizona<br />

or more than<br />

20 years, <strong>the</strong><br />

F<br />

Women’s Active<br />

20-30 Club<br />

<strong>of</strong> Sou<strong>the</strong>rn<br />

Arizona have provided vital support<br />

to <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> and our efforts<br />

in various research areas. This year’s<br />

Cocktailing for a Cause, with its<br />

poker tournament and gourmet<br />

<strong>of</strong>ferings, enabled <strong>the</strong>m to donate<br />

$5,000 to <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>.<br />

PANDA (People Acting Now<br />

Discover Answers)<br />

his year<br />

marked<br />

T<br />

<strong>the</strong> 10th<br />

anniversary<br />

<strong>of</strong> PANDA,<br />

who celebrated<br />

with <strong>the</strong>ir golf tournament and<br />

signature “Children Helping<br />

Children” Fashion Show. The<br />

PANDAs raised more than<br />

$750,000 toward <strong>the</strong> creation <strong>of</strong> <strong>the</strong><br />

PANDA Children’s Neurological<br />

<strong>Center</strong>. The <strong>Center</strong> will provide<br />

comprehensive care for children<br />

with a variety <strong>of</strong> neurological<br />

conditions.<br />

Raise a Racquet for Kids<br />

ven rain didn’t diminish <strong>the</strong><br />

determination and passion <strong>of</strong><br />

E<br />

<strong>the</strong> Raise<br />

a Racquet<br />

for Kids<br />

volunteers!<br />

This year’s<br />

tennis<br />

tournament<br />

featured a<br />

new kids-only<br />

tournament<br />

and lively<br />

entertainment<br />

from Tucson High School’s steel<br />

drum band. RARK raised nearly<br />

$50,000 to support pediatric cancer<br />

research.<br />

Additional Thanks<br />

and Gratitude!<br />

In <strong>2009</strong>, <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> welcomed<br />

<strong>the</strong> support <strong>of</strong> several new volunteer<br />

groups and events.<br />

• The UA’s Alpha Epsilon Phi sorority<br />

sold beautiful cashmere sweaters to<br />

support <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>.<br />

• The Salpointe Catholic High School<br />

football team raised awareness about<br />

type 1 diabetes through <strong>the</strong>ir Games<br />

for <strong>the</strong> Greater Good. The entire school<br />

got involved, delivering Lancer bags<br />

filled with toys for newly diagnosed<br />

patients, and creating “Denim for<br />

Diabetes” ribbons.<br />

• The Gaslight Theatre actors and staff<br />

donated <strong>the</strong>ir time and talents to put<br />

toge<strong>the</strong>r a live show and auction,<br />

inspired by a loved one who lives with<br />

type 1 diabetes. Proceeds benefitted<br />

type 1 diabetes research and clinical care.<br />

• The sad and untimely loss <strong>of</strong> <strong>the</strong>ir<br />

daughter, Marisa Ann, inspired Laura<br />

and Delbert Gallego to establish <strong>the</strong><br />

Marisa Ann Gallego Foundation.<br />

They hosted <strong>the</strong> first annual iMAGine<br />

A Cure Golf Tournament benefitting<br />

cancer research.<br />

• The Placencia family, who lost <strong>the</strong>ir<br />

beloved son, Stephen, to cancer, used<br />

<strong>the</strong>ir tragedy for good, forming <strong>the</strong><br />

Kick Cancer for Stephen Foundation<br />

and donating several gaming systems<br />

to our hematology/oncology clinic.<br />

• The Tucson Toros named <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong> <strong>the</strong>ir charity <strong>of</strong> choice for<br />

<strong>the</strong> annual 4th <strong>of</strong> July Star Spangled<br />

Spectacular and invited one <strong>of</strong> our<br />

diabetes patients to throw out <strong>the</strong><br />

first pitch.<br />

• The Arizona Diamondbacks held a<br />

pediatric cancer awareness night and<br />

invited our cancer patients, survivors,<br />

and <strong>the</strong>ir families to enjoy a carefree<br />

night <strong>of</strong> baseball.<br />

Opening Soon! Diamond<br />

Children’s Medical <strong>Center</strong><br />

T<br />

he excitement is<br />

growing! Construction<br />

is nearing completion<br />

on Diamond Children’s<br />

Medical <strong>Center</strong>. The<br />

facility will open in<br />

phases starting in April<br />

2010. The grand opening<br />

<strong>of</strong> <strong>the</strong> lobby is scheduled for September 2010.<br />

Please visit www.diamondchildrens.org for updates.<br />

Tours:<br />

If you would like a tour <strong>of</strong> <strong>the</strong> <strong>Steele</strong> Children’s<br />

<strong>Research</strong> <strong>Center</strong> and Diamond Children’s, please<br />

contact Mariana Vazquez at (520) 626-9773,<br />

vazquez@peds.arizona.edu.<br />

Donations:<br />

If you are interested in supporting <strong>the</strong> doctors and<br />

programs <strong>of</strong> Diamond Children’s or <strong>the</strong> research<br />

(conducted through <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>), you may<br />

donate online at www.steelecenter.arizona.edu, or<br />

use <strong>the</strong> envelope enclosed with this report. For more<br />

information, please contact Lori Stratton, Director <strong>of</strong><br />

Development for <strong>the</strong> <strong>Steele</strong> <strong>Center</strong>, at (520) 626-7799,<br />

stratton@peds.arizona.edu.<br />

If you are interested in supporting <strong>the</strong> “bricks and<br />

mortar” <strong>of</strong> Diamond Children’s, you may donate<br />

online at www.diamondchildrens.org. For more<br />

information, please contact Tom Sanders, Senior<br />

Development Officer, UMC Foundation, (520) 694-<br />

6599, tsanders@umcaz.org, or Richelle Litteer, Major<br />

Gifts Officer, (520) 694-1324, rlitteer@umcaz.edu.<br />

11


12<br />

Spotlight On Our Patients: <strong>Steele</strong> Story Project<br />

ive <strong>of</strong> our patients participated in <strong>the</strong> <strong>Steele</strong> Story Project to help raise awareness about <strong>the</strong> <strong>Steele</strong> Children’s<br />

F<strong>Research</strong> <strong>Center</strong>. Pr<strong>of</strong>essional photographer Lyra Waggoner photographed each child. We thank our advisory<br />

board members who generously underwrote <strong>the</strong> costs for this project.<br />

Gavin: When born, Gavin couldn’t<br />

eat. He was diagnosed with “EG”<br />

(eosinophilic gastroenteritis), a<br />

painful GI disorder that causes<br />

nausea, vomiting, stomach pain<br />

and choking. Under Dr. Ghishan’s<br />

care, Gavin quickly improved.<br />

After five months on a feeding<br />

tube, his parents were able to<br />

introduce solid foods into Gavin’s<br />

diet. Now 4, “he can eat almost<br />

anything,” says his mom, Erin.<br />

Ian: “When I grow up, I want<br />

to be like Dr. Griffin,” says Ian<br />

about his <strong>Steele</strong> <strong>Center</strong> pediatric<br />

endocrinologist, Kurt Griffin,<br />

PhD, MD. Diagnosed with type 1<br />

diabetes when he was 3, Ian, now<br />

5, uses an insulin pump to manage<br />

his diabetes. “Ian has so much<br />

more freedom with <strong>the</strong> pump,”<br />

says his mom, Lisa.<br />

Ilaria: Three days after she turned<br />

3, Ilaria was diagnosed with yolk<br />

sac germ cell cancer. A tumor <strong>the</strong><br />

size <strong>of</strong> an adult fist was found<br />

in <strong>the</strong> center <strong>of</strong> her chest. “We<br />

were devastated,” says Ilaria’s dad,<br />

Colin. After major surgery to<br />

remove <strong>the</strong> tumor and four rounds<br />

<strong>of</strong> chemo<strong>the</strong>rapy, Ilaria, now 5, is<br />

in remission. “She’s doing great,”<br />

says her pediatric oncologist,<br />

Emmanuel Katsanis, MD.<br />

Jade: Eight-year-old Jade<br />

recently was diagnosed with<br />

supraventricular tachycardia (SVT),<br />

a heart-rhythm disorder that causes<br />

arrhythmia and a rapid heart rate.<br />

Under <strong>the</strong> care <strong>of</strong> her pediatric<br />

cardiologist, Dr. Santiago Valdés,<br />

Jade underwent a successful<br />

cardiac ca<strong>the</strong>terization procedure<br />

that removed <strong>the</strong> extra electrical<br />

connection between <strong>the</strong> top and<br />

bottom chambers <strong>of</strong> her heart.<br />

“She feels wonderful,” says Jade’s<br />

mom, Sherry.<br />

Syd: Five-year-old Syd loves to listen<br />

to classical music and already knows<br />

<strong>the</strong> composers <strong>of</strong> many classical<br />

pieces. Syd receives specialized<br />

care from Sydney Rice, MD, a<br />

developmental pediatrician, to help<br />

with some <strong>of</strong> his neurological and<br />

behavioral challenges. “Syd has<br />

improved tremendously,” says his<br />

dad, Dennis.<br />

Boxed note cards (10 cards per box) are available for a<br />

donation <strong>of</strong> $20 or more. To order, contact Laura Hopkins<br />

at (520) 626-9618 or hopkins@peds.arizona.edu.<br />

Community-based Fundraising:<br />

Canister and Dollar Campaigns<br />

e are grateful for <strong>the</strong> dedicated<br />

Wleadership <strong>of</strong> <strong>Steele</strong> Children’s<br />

<strong>Research</strong> <strong>Center</strong> advisory board<br />

members Bill Cox and<br />

DeeAnne Gibbons.<br />

They created <strong>the</strong><br />

idea for <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong> “canister” and<br />

“dollar” campaigns<br />

to raise money for<br />

<strong>the</strong> <strong>Steele</strong> <strong>Center</strong> and<br />

increase pubic awareness.<br />

Funds raised through <strong>the</strong>se<br />

In September, <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong> received a Hyundai<br />

Hope on Wheels grant to<br />

benefit pediatric cancer<br />

research. <strong>Steele</strong> <strong>Center</strong><br />

pediatric oncologist Brenda<br />

Wittman, MD, was chosen as<br />

a Hyundai Scholar and<br />

received $20,000 for her research in bacterial<br />

infection and blood clotting related to central<br />

venous ca<strong>the</strong>ters. Dr. Wittman received <strong>the</strong> funding<br />

at a special “Handprint Ceremony,” and our<br />

pediatric cancer patients were invited to participate<br />

in this fun and paint-filled event. Jim Click<br />

Automotive donated an additional $20,000 for a<br />

total <strong>of</strong> $40,000 to support Dr. Wittman’s research!<br />

community-based campaigns will<br />

support <strong>Steele</strong> <strong>Center</strong> programs<br />

with <strong>the</strong> greatest need.<br />

The “canister campaign”<br />

has put change canisters<br />

at many local businesses<br />

throughout Tucson<br />

and Sou<strong>the</strong>rn Arizona.<br />

They feature Faith—a<br />

young cancer survivor<br />

treated by <strong>Steele</strong> <strong>Center</strong> pediatric<br />

oncologists.<br />

The “dollar campaign” lets you<br />

support <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> for as<br />

little as $1! As our dollar campaign<br />

grows, <strong>the</strong> cards will be available<br />

in stores throughout Tucson.<br />

To find locations near you for<br />

both campaigns, or if you would<br />

like to add <strong>the</strong> campaigns to your<br />

business, please contact Laura<br />

Hopkins at (520) 626-9618,<br />

hopkins@peds.arizona.edu, or:<br />

www.steelecenter.arizona.edu/<br />

annualgiving.asp.<br />

<strong>Steele</strong> <strong>Center</strong> Receives Grant from<br />

Hyundai Hope on Wheels<br />

13


14<br />

Facts & Figures<br />

he UA <strong>Steele</strong> Children’s<br />

T<strong>Research</strong> <strong>Center</strong> serves<br />

children throughout<br />

Arizona and neighboring<br />

states, focusing primarily<br />

on difficult-to-treat diseases<br />

like pediatric cancers, type<br />

1 diabetes, autism spectrum<br />

disorders, congenital heart<br />

disease and gastrointestinal<br />

disorders such as Crohn’s<br />

disease and eosinophilic<br />

esophagitis.<br />

<strong>Steele</strong> <strong>Center</strong> pediatricians<br />

and pediatric specialists<br />

care for children and <strong>the</strong>ir<br />

families in approximately<br />

60,000 patient visits a year.<br />

They provide <strong>the</strong> type<br />

<strong>of</strong> support and cuttingedge<br />

care that comes<br />

from being an academic<br />

research institution.<br />

Physician-scientists at <strong>the</strong><br />

<strong>Steele</strong> <strong>Center</strong> focus on<br />

investigating <strong>the</strong> causes <strong>of</strong><br />

pediatric diseases and work<br />

to discover new treatments<br />

and <strong>the</strong>rapies for children<br />

suffering with illness.<br />

Federal and state grants<br />

help fund scientific<br />

investigation, but<br />

philanthropy is an<br />

important catalyst for<br />

nurturing new ideas<br />

because it serves as a<br />

springboard for securing<br />

government aid in <strong>the</strong><br />

future. Only 10% <strong>of</strong><br />

all donations are used<br />

for development and<br />

fundraising efforts.<br />

We thank each <strong>of</strong> our<br />

donors for <strong>the</strong>ir investment<br />

in <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> and<br />

children’s health.<br />

FY 08-09 Where Philanthropy Money Comes From<br />

FY 08-09 Where Philanthropy Funds Were Directed<br />

Faculty Highlights <strong>2009</strong><br />

Brent Barber, MD, promoted to Associate Pr<strong>of</strong>essor, Clinical<br />

Pediatrics, Section <strong>of</strong> Cardiology.<br />

Christopher Cunniff, MD, Pr<strong>of</strong>essor and Chief, Section <strong>of</strong><br />

Genetics; elected President <strong>of</strong> <strong>the</strong> American Board <strong>of</strong> Medical Genetics<br />

(ABMG); received 5-year, $1.25 million grant from <strong>the</strong> <strong>Center</strong>s for<br />

Disease Control and Prevention to study <strong>the</strong> prevalence <strong>of</strong> Fetal<br />

Alcohol Syndrome in children throughout Arizona and Nevada.<br />

Cori Daines, MD, promoted to Associate Pr<strong>of</strong>essor, Clinical<br />

Pediatrics, Section <strong>of</strong> Pulmonary, Allergy and Immunology.<br />

Bohuslav Dvorak, PhD, promoted to <strong>Research</strong> Pr<strong>of</strong>essor, Section<br />

<strong>of</strong> Neonatology; Publication: Bifidobacterium bifidum Improves Intestinal<br />

Integrity in a Rat Model <strong>of</strong> Necrotizing Enterocolitis; American Journal<br />

<strong>of</strong> Physiology: Gastrointestinal and Liver Physiology, <strong>2009</strong>; 297: G1-G10;<br />

received a two-year NIH R21 grant, “Regulation <strong>of</strong> Immune Reactions<br />

by Syn<strong>the</strong>tic Thioglucans,” in collaboration with <strong>the</strong> <strong>University</strong> <strong>of</strong><br />

Louisville.<br />

Sean P. Elliott, MD, Associate Pr<strong>of</strong>essor, Section <strong>of</strong> Infectious<br />

Diseases; inducted into Alpha Omega Alpha at UA College <strong>of</strong><br />

Medicine; received UA College <strong>of</strong> Medicine Faculty Teaching Award,<br />

“Educator <strong>of</strong> <strong>the</strong> Year Lifetime Award—Years III and IV”; Publication:<br />

The Spectrum and Presentation <strong>of</strong> Disseminated Coccidioidomycosis;<br />

American Journal <strong>of</strong> Medicine, <strong>2009</strong>; 122(5): 770-777.<br />

Robert P. Erickson, MD, Pr<strong>of</strong>essor, Section <strong>of</strong> Genetics;<br />

Publication: Autosomal Recessive Disease among <strong>the</strong> Athabaskans<br />

<strong>of</strong> <strong>the</strong> Southwestern United States: Recent Advances and Implications<br />

for <strong>the</strong> Future; American Journal <strong>of</strong> Medical Genetics A, <strong>2009</strong>;<br />

149A:2602-2611.<br />

Fayez K. Ghishan, MD, Pr<strong>of</strong>essor and Department Head, Section<br />

<strong>of</strong> Gastroenterology and Nutrition; received “Distinguished Alumnus<br />

Award for Achievement,” from <strong>the</strong> <strong>University</strong> <strong>of</strong> Iowa Carver<br />

College <strong>of</strong> Medicine; received two-year NIH “American Recovery<br />

and Reinvestment” grant to study <strong>the</strong> role <strong>of</strong> calcium in IBD-related<br />

bone loss. Publication: Tumor Necrosis Factor Alpha Down-Regulates<br />

Intestinal NHE8 Expression by Reducing Basal Promoter Activity;<br />

American Journal <strong>of</strong> Physiology: Cell Physiology, <strong>2009</strong>; 296(3): C489-97.<br />

Melissa Halpern, PhD, promoted to <strong>Research</strong> Associate Pr<strong>of</strong>essor,<br />

Section <strong>of</strong> Neonatology; Publication: Bifidobacterium bifidum Improves<br />

Intestinal Integrity in a Rat Model <strong>of</strong> Necrotizing Enterocolitis; American<br />

Journal <strong>of</strong> Physiology: Gastrointestinal and Liver Physiology, <strong>2009</strong>; 297:<br />

G1-G10.<br />

Cleo Hardin, MD, Associate Pr<strong>of</strong>essor and Chief, Section <strong>of</strong><br />

Hospital Medicine & Outreach; earned “Fellow in Hospital Medicine”<br />

(FHM) designation from <strong>the</strong> Society <strong>of</strong> Hospital Medicine.<br />

Emmanuel Katsanis, MD, Pr<strong>of</strong>essor and Chief, Section <strong>of</strong><br />

Hematology/Oncology; named “Leading Edge <strong>Research</strong>er” at <strong>the</strong><br />

<strong>University</strong> <strong>of</strong> Arizona; awarded five-year R01 grant from <strong>the</strong> NIH,<br />

“Immuno<strong>the</strong>rapy for Chronic Myelogenous Leukemia.” Publication:<br />

Signaling Pathways Induced by a Tumor-derived Vaccine in Antigen<br />

Presenting Cells; Immunobiology, <strong>2009</strong>; Oct. 30.<br />

Pawel Kiela, DVM, PhD, <strong>Research</strong> Associate Pr<strong>of</strong>essor, Section<br />

<strong>of</strong> Gastroenterology and Nutrition; received two-year NIH “American<br />

Recovery and Reinvestment” grant to study <strong>the</strong> role <strong>of</strong> calcium in<br />

IBD-related bone loss.<br />

Nicolas Larmonier, PhD, promoted to <strong>Research</strong> Associate<br />

Pr<strong>of</strong>essor, Section <strong>of</strong> Hematology/Oncology; Publication: Imatinib<br />

Mesylate Suppresses CD4+CD25+ Regulatory T Cell Activity and<br />

Enhances Active Immuno<strong>the</strong>rapy Against BCR-ABL Negative Tumors;<br />

Journal <strong>of</strong> Immunology, Nov. 181:6955-63.<br />

William Madden, MD, Pr<strong>of</strong>essor and Chief, Section <strong>of</strong> General<br />

Pediatrics; received UA College <strong>of</strong> Medicine Faculty Teaching Award,<br />

“Dean’s List for Excellence in Teaching Award, Year III.”<br />

Ricardo Samson, MD, Pr<strong>of</strong>essor and Chief, Section <strong>of</strong> Cardiology;<br />

asked to serve as Associate Science Editor for <strong>the</strong> American Heart<br />

Association.<br />

Ziad Shehab, MD, Pr<strong>of</strong>essor, Section <strong>of</strong> Infectious Diseases; UA<br />

College <strong>of</strong> Medicine Faculty Teaching Award, “Outstanding Achievement<br />

in Teaching by a Clerkship or Elective Award for Years III and IV.”<br />

Andreas Theodorou, MD, Pr<strong>of</strong>essor and Chief, Section <strong>of</strong><br />

Critical Care; Publication: Antivenom for Critically Ill Children with<br />

Neurotoxicity from Scorpion Stings; The New England Journal <strong>of</strong> Medicine,<br />

May <strong>2009</strong>, Vol. 360:2090-2098. Named a “Best Doctor,” <strong>2009</strong>.<br />

Richard Wahl, MD, promoted to Pr<strong>of</strong>essor, Clinical Pediatrics,<br />

Section <strong>of</strong> General Pediatrics.<br />

The Department <strong>of</strong> Pediatrics Welcomed New Faculty in <strong>2009</strong><br />

Rachel Cramton, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Clinical Pediatrics<br />

Hospital Medicine/Outreach<br />

Nancy Gruchala, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Clinical Pediatrics<br />

Hospital Medicine/Outreach<br />

Margaret Trouard, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Clinical Pediatrics<br />

Critical Care<br />

Katri Typpo, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Clinical Pediatrics<br />

Critical Care<br />

15


16<br />

Inspired<br />

We are inspired by <strong>the</strong> kindness and generosity <strong>of</strong> our donors and are thankful for every gift made to <strong>the</strong> <strong>Steele</strong> Children’s<br />

<strong>Research</strong> <strong>Center</strong> that allows us to provide today’s care and tomorrow’s cures. We want to give special thanks to <strong>the</strong><br />

following cash and in-kind donors who gave $1,000 or more from January through December <strong>2009</strong>.<br />

$500,000+<br />

PANDA—Phoenix Women’s<br />

Board<br />

$250,000 - $499,999<br />

Arizona Elks Major Projects<br />

$100,000 - $249,999<br />

Fa<strong>the</strong>r’s Day Council Tucson<br />

The <strong>Steele</strong> Foundation, Inc.<br />

$50,000 - $99,999<br />

Jacquelynn and Bennett Dorrance<br />

$25,000 - $49,999<br />

Ashley and Chris Baiker<br />

Dorrance Family Foundation<br />

Gifts in Honor <strong>of</strong> Rick Fink—<br />

Fa<strong>the</strong>r <strong>of</strong> <strong>the</strong> Year <strong>2009</strong><br />

Gifts in Honor <strong>of</strong> Gary Kippur—<br />

Fa<strong>the</strong>r <strong>of</strong> <strong>the</strong> Year <strong>2009</strong><br />

Gifts in Honor <strong>of</strong> Jose Rincon—<br />

Fa<strong>the</strong>r <strong>of</strong> <strong>the</strong> Year <strong>2009</strong><br />

Gifts in Honor <strong>of</strong> Les White—<br />

Fa<strong>the</strong>r <strong>of</strong> <strong>the</strong> Year <strong>2009</strong><br />

J.W. Kieckhefer Foundation<br />

Raise a Racquet for Kids<br />

Tee Up For Tots, Inc.<br />

Tohono O’odham Gaming Enterprise<br />

$15,000 - $24,999<br />

Anonymous<br />

Robyn and Mike DeBell<br />

Maxine and Ralph Henig<br />

Hyundai Hope On Wheels<br />

Jim Click Automotive<br />

Sharon and Donald Ulrich<br />

$10,000 - $14,999<br />

Adelante Foundation<br />

Anonymous<br />

BlueCross BlueShield<br />

Hazel Hare<br />

Karen and Bob Hobbs<br />

Jasam Foundation<br />

Joseph Stanley Leeds Foundation<br />

Carey and John Musil<br />

Ramiro G. Peru<br />

WellPoint Foundation<br />

$5,000 - $9,999<br />

Sydney and Bob Anderson<br />

Bashas’ Charitable Fund<br />

Brenda and George Brimhall<br />

Laurie and Drew Brown<br />

Cardinal Charities, Inc.<br />

Amy and Keith Carney<br />

Missy and Michael Cooley<br />

Cay Cowie<br />

CVS Caremark Corporation<br />

Ardie and Steve Evans<br />

Joan and Fayez Ghishan<br />

DeeAnne and Gregg Gibbons<br />

GoDaddy.com<br />

Shannon and Robert Goldwater<br />

Penny and Larry Gunning<br />

Ruth Ann and Tom Hornaday<br />

Immunovative Therapies, Ltd.<br />

Stephanie and Guy Inzalaco<br />

Steven A. Lightman<br />

Marisa Ann Gallego Foundation<br />

Faye Morse<br />

Melissa and David Mullard<br />

Joellen and Tim Rannow<br />

RBC Dain Rauscher Foundation<br />

Adriana and Jose Rincon<br />

Susan and Larry Ring<br />

Shamrock Foods Company<br />

Linda and William Skov<br />

Nancy and John Teets<br />

The Gaslight Theatre<br />

Benjamin C. Thomas<br />

Tammy and Jon Underwood<br />

Cindy and Les White<br />

Allie and Mike Wilmink<br />

Women <strong>of</strong> <strong>the</strong> Active 20-30 Club<br />

Helen and Chris Yeung<br />

$2,500 - $4,999<br />

Arizona Mail Order, Inc.<br />

Alice and Paul Baker<br />

Laura and Michael Bill<br />

Lee and Frank Bowman<br />

Campbell, Yost, Clare & Norell, P.C.<br />

Caremark Rx, Inc.<br />

Carondelet Health Network<br />

Catalina Mechanical Contracting, Inc.<br />

Kyle and Casey Christensen<br />

Desert Institute for Spine Care, P.C.<br />

DMB Associates<br />

Eli Lilly & Co.<br />

Micheline and Bruce Etkin<br />

Fennemore Craig, P.C.<br />

Stanley D. Friedman<br />

Melinda and John A. Gulick III<br />

Henry Pope Foundation<br />

Sue and Stewart Jean<br />

Jim Boyle Dairy<br />

Linda Kaplan<br />

Lori and James Kelly<br />

Lorna and Mark Kipphut<br />

Jane and Phil Lacovara<br />

Lundy Medical Products, LLC<br />

Magnum Paving, Inc.<br />

Marianne Cracchiolo Mago and<br />

James Mago<br />

Marc Walker Enterprises, Inc.<br />

Judee and David Morrison<br />

Oser Communications Group<br />

PepsiCo Foodservice<br />

Carolyn Ponder<br />

Carol and Jim Schmidt<br />

Sara and Steven Schramm<br />

Susie and Les Small<br />

Maria and Mark Syms<br />

The Hart Family-Orepac Foundation<br />

Art Valles<br />

Kathy and Tom Van Arsdale<br />

Jon C. Walker<br />

Kathy and Craig Walker<br />

Lola and Carl White<br />

$1,000 - $2,499<br />

AAC Structures <strong>of</strong> Arizona, LLC<br />

Anonymous<br />

A.F. Sterling Homes<br />

Alana Studios <strong>of</strong> Design, LLC<br />

Alliance Bank <strong>of</strong> Arizona<br />

Alpha Epsilon Phi Sorority<br />

Amcep Metals, Inc.<br />

American Openings, Inc.<br />

Animas Corporation<br />

Ara Parseghian Medical<br />

<strong>Research</strong> Foundation<br />

Arizona-Sonora Desert Museum<br />

LaDonna and Robin Aron<strong>of</strong>f<br />

Bank <strong>of</strong> Tucson<br />

Carie and Mike Baumann<br />

Beach Fleischman PC<br />

Deanna and Kemp Biddulph<br />

Valerie and Leland Bisbee III<br />

BolchalkFReY Marketing<br />

Louis R. Breton<br />

Broadband Dynamics, LLC<br />

Judy and Darren Burke<br />

Cactus Transport, Inc.<br />

Emily and Daniel Calihan<br />

Norma and Martin Camacho<br />

Joan Kaye Cauthorn and Robert<br />

Cauthorn<br />

Tara and Mark Cavanaugh<br />

Chapman Automotive<br />

Chartwell Group, LLC<br />

John T. Chesley<br />

Ginny Clements<br />

Vicki and Jim Click Jr.<br />

CMS, LLC<br />

Ka<strong>the</strong>rine and Bradley Combs<br />

Marilyn S. Congleton<br />

Donna and Leo Connolly<br />

Lynne K. Cook<br />

Tiffany Crane<br />

Tina and David Curran<br />

David & Sondra Mack Foundation<br />

Carol and Wallace Davis<br />

Kristin and Harrison Dean<br />

Delta Delta Delta Tucson<br />

Alumnae Chapter<br />

Desert Metals Recycling, Inc.<br />

Joan and Don Diamond<br />

Diamond Ventures, Inc.<br />

Marlis and James Dinning<br />

Karen and Mark Doerflein<br />

Dover Associates, LLC<br />

Employer Solutions Group<br />

Enterprise Rent-A-Car Foundation<br />

E<strong>the</strong>l & Jerry Timan Memorial<br />

Family Fund<br />

Meghan and Court Fable<br />

Carmen and Ge<strong>of</strong>frey Ferlan<br />

Susan and Thomas Firth<br />

Pam and Gary Fitzgerald<br />

Susan and David French<br />

Diana and David Freshwater<br />

Anne Fritz<br />

Gary and Teresa Yourtz Foundation<br />

Genentech USA<br />

Alexis and Boz Glascock<br />

Ellen and David Goldstein<br />

Hacienda Del Sol<br />

Megan and Alfred Hackbarth III<br />

Patricia and Howard Harpst<br />

Jamie Cain and Kenneth Head<br />

Stephanie and David Helsten<br />

Becky Hill<br />

Megan and John Hink<br />

Dennis W. Hitzeman<br />

Laura L. Hopkins<br />

Susan and Jim Hunter<br />

Elizabeth and William Imparato<br />

Jewish Federation <strong>of</strong> Sou<strong>the</strong>rn<br />

Arizona<br />

Mark Joseph<br />

J P Industries, Inc.<br />

Tandy and Gary Kippur<br />

Kelly and James Kirke<br />

Kitchell Corporation<br />

Daniel Kivel<br />

Julie and Scott Klewer<br />

Julie and Joe Koeth<br />

Kirsten Korosec<br />

Jill Kusy<br />

Wendy and Sage Lentz<br />

Lewis and Roca LLP<br />

Loews Ventana Canyon<br />

Longbow Golf Club Associates, LLC<br />

Lunda & Associates, P.C.<br />

Macerich Management Company<br />

Jean and Bill Mack<br />

Beth and Bill Madden<br />

Carole and William Mallender<br />

Lisa and Gregory Mallender<br />

Mariana Vazquez and Justin Maloney<br />

Maurice R. & Meta G. Gross<br />

Foundation<br />

John Maus<br />

Amy and Sloane McFarland<br />

McNamara, Goldsmith &<br />

McDonald, P.C.<br />

Clark M. Merkley<br />

Mesch, Clark & Rothschild P.C.<br />

Metal Management Arizona, LLC<br />

Michael P. Bergeron Foundation,<br />

Inc.<br />

Karen and Alexander Mlawsky<br />

Denise A. Monti<br />

Linda and Fred Nachman<br />

Sylvia and Andy Norell<br />

Nova Financial & Investment<br />

Corporation<br />

Novo Nordisk Pharmaceuticals, Inc.<br />

Charles D. Oliver III<br />

Christine and James Orders<br />

Dorothy and Julius Parker<br />

Pfizer, Inc.<br />

Nicole and Larry Pike<br />

Pima County Medical Foundation<br />

Pima County Medical Society<br />

Deborah Oseran and Bobby Present<br />

Monica and David Ramsze<br />

Judy and Bill Ray<br />

Susan B. Rehorn<br />

Gabrielle and Robert Rife<br />

Kathy and Gerald Ritt<br />

Robert J. Kelly DMD, P.C.<br />

Peggy and Jon Rowley<br />

Ryley, Carlock & Applewhite<br />

Sage Tax Group<br />

Sahuaro High School Dance Team<br />

Stephanie and Ricardo Samson<br />

Gretchen and Ryan Schubert<br />

Leila and Ziad Shehab<br />

Casey and James Simmons<br />

Siskiyou Forest Products<br />

Lynne and Volker Sonntag<br />

Lori and Chip Stratton<br />

Cecelia D. Terry<br />

TEVA Pharmaceuticals USA<br />

Sandi and Purdom Thomas<br />

Robyn Kessler and Jeffrey Timan<br />

Kati and Chris Travelle<br />

U.S. Foodservice<br />

Terrye L. Underwood<br />

United Commercial Travelers<br />

<strong>University</strong> Medical <strong>Center</strong><br />

<strong>University</strong> <strong>of</strong> Arizona Foundation<br />

Valley <strong>of</strong> <strong>the</strong> Sun Fine Wines<br />

Blake and Johnjay Van Es<br />

Vantage West Credit Union<br />

Michelle and Marc Walker<br />

Megan and Kris Wall<br />

Donna and T.K. Warfield<br />

Thomas W. Warne<br />

Wells Fargo & Company<br />

Wells Fargo Bank, N.A.<br />

Carol M. Williams<br />

Monica and John Woudenberg<br />

Jaime and Bradley Wright<br />

Victoria and Richard York<br />

In-kind Donors<br />

Abbott Taylor Jewelers<br />

American Openings, Inc.<br />

Christina and K.C. An<br />

Arizona Elks Major Projects<br />

BizTucson<br />

Broadmoor Spa, Golf and Tennis Club<br />

Anita L. Burg<br />

Enchantment Resort<br />

Fairmont Southampton<br />

Jon Wolf Photography, Inc.<br />

Kick Cancer for Stephen Foundation<br />

La Jolla Beach and Tennis Club<br />

Loews Ventana Canyon<br />

St. Regis Resort<br />

Terranea Resort<br />

Tucson Police Foundation<br />

US Airways Group<br />

17


Department <strong>of</strong> Pediatrics Faculty Fayez K. Ghishan, MD, Pr<strong>of</strong>essor and Head<br />

Cardiology<br />

Section Chief: Ricardo Samson, MD<br />

Pr<strong>of</strong>essor<br />

Brent Barber, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Stan Goldberg, MD<br />

Pr<strong>of</strong>essor Emeritus<br />

Scott Klewer, MD<br />

Pr<strong>of</strong>essor<br />

Daniela Lax, MD<br />

Associate Pr<strong>of</strong>essor<br />

Gregory Mike Nichols, MD<br />

Clinical Lecturer<br />

Santiago Valdés, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Critical Care<br />

Section Chief: Andreas Theodorou, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Marc Berg, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Hillary Franke, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Mary Gaspers, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Michael Karadsheh, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Robyn Meyer, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Katri Typpo, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Mark Witten, PhD<br />

<strong>Research</strong> Pr<strong>of</strong>essor<br />

Simon Wong, MD<br />

<strong>Research</strong> Associate Pr<strong>of</strong>essor<br />

Developmental & Behavioral<br />

Pediatrics<br />

Sydney A. Rice, MD, MS<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Margaret Trouard, MD<br />

Clinical Lecturer<br />

Endocrinology<br />

Section Chief: Mark Wheeler, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Kurt Griffin, PhD, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Chetan Patel, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Gastroenterology<br />

Section Chief: Hassan Hassan, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Fayez K. Ghishan, MD<br />

Pr<strong>of</strong>essor and Department Head<br />

Pawel Kiela, PhD<br />

<strong>Research</strong> Associate Pr<strong>of</strong>essor<br />

Hua Xu, PhD<br />

<strong>Research</strong> Associate Pr<strong>of</strong>essor<br />

General Pediatrics<br />

Section Chief: Kimberly Gerhart, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Conrad Clemens, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Thomas Ball, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Kathryn Bowen, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Karen Davenport, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Tracey Kurtzman, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

William Madden, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

William Marshall Jr., MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Richard Wahl, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Genetics<br />

Section Chief: Christopher Cunniff, MD<br />

Pr<strong>of</strong>essor<br />

Robert Erickson, MD<br />

Pr<strong>of</strong>essor<br />

John Meaney, PhD<br />

<strong>Research</strong> Lecturer<br />

Hematology/Oncology<br />

Section Chief: Emmanuel Katsanis, MD<br />

Pr<strong>of</strong>essor<br />

Michael Graham, MD<br />

Associate Pr<strong>of</strong>essor<br />

Nicolas Larmonier, PhD<br />

<strong>Research</strong> Associate Pr<strong>of</strong>essor<br />

Brenda Wittman, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Hospital Medicine/Outreach<br />

Section Chief: Cleo Hardin, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Rachel Cramton, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Nancy Gruchala, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Eliza Holland, MD<br />

Clinical Lecturer<br />

Zakiya Karim, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Chan Lowe, Jr., MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Hengameh Rastegar-Murphy, MD<br />

Clinical Lecturer<br />

Jasna Seserinac, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Infectious Diseases<br />

Section Chief: Ziad Shehab, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Sean Elliott, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Neonatology<br />

Section Chief: Alan Bedrick, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Jasmine Ahmed, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Bohuslav Dvorak, PhD<br />

<strong>Research</strong> Pr<strong>of</strong>essor<br />

Edith Edde, DO<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Melissa Halpern, PhD<br />

<strong>Research</strong> Associate Pr<strong>of</strong>essor<br />

Ca<strong>the</strong>rine Tsai, MD<br />

Assistant Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Nephrology<br />

Section Chief: Emmanuel Apostol, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Pulmonology, Allergy and Immunology<br />

Section Chief: Wayne Morgan, MD<br />

Pr<strong>of</strong>essor<br />

Mark Brown, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Cori Daines, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Michael Daines, MD<br />

Assistant Pr<strong>of</strong>essor<br />

Roni Grad, MD<br />

Associate Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Fernando Martinez, MD<br />

Pr<strong>of</strong>essor<br />

Anne Wright, PhD<br />

<strong>Research</strong> Pr<strong>of</strong>essor<br />

Phoenix Clerkship Program<br />

Kipp Charlton, MD<br />

Clinical Associate Pr<strong>of</strong>essor<br />

Maricopa Medical <strong>Center</strong><br />

John Muhm Jr., MD<br />

Clinical Assistant Pr<strong>of</strong>essor<br />

Phoenix Children’s Hospital<br />

Kristin Samaddar, MD<br />

Clinical Assistant Pr<strong>of</strong>essor<br />

St. Joseph’s Hospital<br />

Mitchell Shub, MD<br />

Pr<strong>of</strong>essor, Clinical Pediatrics<br />

Phoenix Children’s Hospital<br />

<strong>Steele</strong> <strong>Center</strong> Advisory Boards<br />

Tucson<br />

Advisory Board<br />

Chair: Phil Lacovara, PhD<br />

Active Members<br />

Louis Breton<br />

Ginny Clements<br />

Bill Cox<br />

Bert Dover<br />

Jay Foust<br />

DeeAnne Gibbons<br />

Cynthia Goodman Shaw<br />

Linda Immerman-St<strong>of</strong>fers<br />

Beth Koontz<br />

Bill Krauss<br />

Troy Little<br />

Andrea Malis<br />

Andy Norell<br />

Ray Novak, MD<br />

Kathy Orr<br />

Larry Ring<br />

Steve Rosenberg<br />

Peggy Rowley<br />

Dian Rutin<br />

Judy Smedes<br />

Jeremy Sohn<br />

Tom Strasburg<br />

Louise Thomas<br />

Consulting Members<br />

Judy Abrams<br />

Joan Kaye Cauthorn<br />

Robert Davis<br />

Norma Feldman<br />

Shirley Fulginiti<br />

Mark Kipphut<br />

Ruth Mondschein, PhD<br />

David Sitton<br />

Credits:<br />

Writer/Editor/Art Director/Designer<br />

Darci Slaten, MA<br />

Director <strong>of</strong> Communications and Marketing<br />

Graphic Design<br />

Roma Krebs, AHSC BioCommunications<br />

Editorial Board<br />

George Humphrey, MA<br />

Director, AHSC Office <strong>of</strong> Public Affairs<br />

Honorary Members<br />

Lissa Marinaro<br />

William Foucher<br />

Linda Lewandowski<br />

Life Members<br />

Joan Diamond<br />

Virginia Furrow, MD<br />

Maxine Henig<br />

Cele Peterson<br />

Lynn Taussig, MD<br />

Louise Thomas<br />

Phoenix<br />

Advisory Board<br />

Chair: Kim Sterling-Heflin<br />

Kirk Aleck, MD<br />

John Checkett<br />

Mary Chick<br />

Robyn DeBell<br />

Jodi Freeman<br />

Penny Gunning<br />

Annette Heasman<br />

Patti Lau<br />

Bill Mack<br />

Phillippa Maltese<br />

Karen Meyer<br />

Andy Plattner<br />

Bill Ridenour<br />

Jan Neal Riemar<br />

Joan Rankin Shapiro, PhD<br />

Mitch Shub, MD<br />

Margo Smith<br />

Greg Stanton<br />

Judy Walruff, PhD<br />

Dick Whitney<br />

Phoenix<br />

Women’s<br />

Advisory Board<br />

(PANDA)<br />

President:<br />

Stephanie Helsten<br />

Trisha Anthony<br />

Tifanny Anton<br />

Ashley Baiker<br />

Sara Baldwin<br />

Charlene Berge-Blum<br />

Alexandra Boyle<br />

Judy Burke<br />

Emily Calihan<br />

Sarah Carlenzoli<br />

Kyle Christensen<br />

Heidi Coupland<br />

Lisa Cowan<br />

Tiffany Crane<br />

Tina Curran<br />

Christy Dean<br />

Kristin Dean<br />

Robyn DeBell<br />

Jacquie Dorrance<br />

Jennifer Dougherty<br />

Debbi Douglas<br />

Kay Eskridge<br />

Meghan Fable<br />

Dana Gapusan<br />

Lora Golke<br />

Melinda Gulick<br />

Penny Gunning<br />

Megan Hackbarth<br />

Tori Heintzelman<br />

Nancy Hepburn<br />

Megan Hink<br />

Ca<strong>the</strong>rine Jacobson<br />

Lori Kelly<br />

Melissa Kenly<br />

Kelly Kirke<br />

Julie Koeth<br />

Photography<br />

Martha Lochert Photography (Cover; About Cover)<br />

Margaret Hartshorn<br />

- AHSC BioCommunications (p. 15)<br />

Laura Hopkins (p. 13)<br />

Francie Placencia (p. 7)<br />

Darci Slaten (all o<strong>the</strong>r photos)<br />

Lyra Waggoner (p. 12)<br />

Pam Kolbe<br />

Wendy Lentz<br />

Kari MacDonald<br />

Amy Mahoney<br />

Lisa Mallender<br />

Lizabeth Mat<strong>the</strong>ws<br />

Traci Mead<br />

Ashley Ragan<br />

Julie Rauch<br />

Judy Ray<br />

Kathy Ritt<br />

Laurie Ritt<br />

Erika Sahagun<br />

Gretchen Schubert<br />

Susie Small<br />

Tracy Smith<br />

Kati Travelle<br />

Gerri Tsantilas<br />

Kristin Ulrich<br />

Tammy Underwood<br />

Julie Vogel<br />

Carol Waldrop*<br />

Kathy Walker<br />

Michelle Walker<br />

Megan Wall<br />

Karin Weiler<br />

Nancy White<br />

Linda Whitney<br />

Allie Wilmink<br />

Susan Wissink<br />

Jaime Wright<br />

Helen Yeung<br />

*In memorium<br />

Golden PANDAs<br />

Carolyn Bosworth<br />

Ann Denk<br />

Suellen Edens<br />

Pam Fitzgerald<br />

Carol Schmidt<br />

Mary Lynn Schmidt<br />

Judy Shannon<br />

Sandi Thomas<br />

Associate<br />

Members<br />

Sydney Anderson<br />

Nancy Berge<br />

Muffie Churchill<br />

Joan Colangelo<br />

Kathy DeSanto<br />

Kelly Eaton<br />

Ardie Evans<br />

Diana Finley<br />

Lindsey Gladwin<br />

Ruthann Grace<br />

Carol Hebets<br />

Karen Hobbs<br />

Michelle Hobbs<br />

RuthAnn Hornaday<br />

Mary Hudak<br />

Jennifer Irby<br />

Kerry Jameson<br />

Cathy Kleeman<br />

Kathleen Lang<br />

Beth Mat<strong>the</strong>ws<br />

Carey Musil<br />

Stacie Olson<br />

Pam Overton<br />

Ka<strong>the</strong>y Plenge<br />

Kerrie Schmidt<br />

Judy Schubert<br />

Lynne Sonntag<br />

Anne Spellman<br />

Kim Sterling-Helfin<br />

Sharon Ulrich<br />

Kathy Van Arsdale<br />

Desha Whitney-Wikle<br />

Additional Assistance<br />

Laura Hopkins<br />

Katie Riley<br />

Thomas S. Sanders<br />

Jean Spinelli<br />

Mariana Vazquez, MS<br />

Lori Stratton, MPH<br />

Additional Writing<br />

Laura Hopkins<br />

18<br />

Director <strong>of</strong> Development<br />

Lori Stratton, MPH<br />

Mariana Vazquez, MS<br />

19


2010 Events<br />

April 10<br />

PANDA 11th Annual<br />

“Children Helping Children”<br />

Fashion Show<br />

Arizona Biltmore Resort and Spa, Phoenix<br />

May 7<br />

Fa<strong>the</strong>r’s Day Council Golf Classic<br />

Loews Ventana Canyon<br />

June 19<br />

Fa<strong>the</strong>rs <strong>of</strong> <strong>the</strong> Year Awards Gala<br />

Loews Ventana Canyon<br />

August 27<br />

Tee Up For Tots Golf Tournament<br />

Hilton El Conquistador<br />

Fall 2010<br />

Raise A Racquet for Kids<br />

Tucson Racquet and Fitness Club<br />

Fall 2010<br />

Runway for <strong>Research</strong><br />

Hilton El Conquistador<br />

December 2010<br />

PANDA 3rd Annual<br />

“Playing FORE PANDA”<br />

Golf Tournament<br />

Phoenix, Arizona<br />

The <strong>University</strong> <strong>of</strong> Arizona<br />

<strong>Steele</strong> Children’s <strong>Research</strong> <strong>Center</strong><br />

Department <strong>of</strong> Pediatrics<br />

PO Box 245073<br />

Tucson, AZ 85724-5073<br />

About <strong>the</strong><br />

<strong>Steele</strong> <strong>Center</strong> Logo<br />

O<br />

ur logo is an incomplete puzzle, with a<br />

child in <strong>the</strong> center. The pieces to <strong>the</strong> puzzle<br />

represent everyone who is integral to improving<br />

children’s health…doctors, nurses, medical staff,<br />

researchers, families, volunteer groups, donors<br />

and o<strong>the</strong>rs. We all can be a piece <strong>of</strong> <strong>the</strong> puzzle,<br />

working toge<strong>the</strong>r to improve children’s health.<br />

The puzzle isn’t finished, because we can’t do it without YOU.<br />

Thank you for your support! To learn more about <strong>the</strong> <strong>Steele</strong><br />

<strong>Center</strong>, please visit www.steelecenter.arizona.edu.<br />

Stay connected to <strong>the</strong> <strong>Steele</strong> <strong>Center</strong><br />

Learn more about what’s happening<br />

at <strong>the</strong> <strong>Steele</strong> <strong>Center</strong> through our Web site:<br />

www.steelecenter.arizona.edu<br />

Stay current with our e-newsletter.<br />

Sign up at: www.steelecenter.arizona.edu<br />

Become our Facebook friend<br />

Follow us on Twitter<br />

NONPROFIT ORG<br />

US POSTAGE PAID<br />

TUCSON ARIZONA<br />

PERMIT NO. 190

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