BUMC Basics.pdf - Anesthesia Home
BUMC Basics.pdf - Anesthesia Home
BUMC Basics.pdf - Anesthesia Home
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• Resistant pathogens: MRSA, VRE, Pseudomonas<br />
• Other infections: Cellulitis, cholangitis, cholecystitis,<br />
diverticulitis, endocarditis, intra-abdominal abscess,<br />
meningitis, sinusitis, thrombophlebitis<br />
• Non-infectious causes: Transfusion reactions, drug<br />
fever, intra-abdominal source (pancreatitis, acute<br />
mesenteric ischemia), thyroid disease, or thromboembolic<br />
disease (DVT/PE)<br />
Work-up and treatment — Consider the following:<br />
• CBC with diff, CMP<br />
• Repeat blood cultures x2<br />
• CMV PCR<br />
• UA/urine culture<br />
• Sputum gram stain/culture<br />
• Change out central lines if >48 hours (venous lines first)<br />
and culture tips<br />
• pCXR<br />
• Stool studies if indicated<br />
• Abdominal ultrasound if indicated<br />
• CT chest, abdomen, or pelvis if indicated<br />
• Bilateral lower extremity Doppler if indicated<br />
• CT sinuses if chronic NG tube<br />
• Empiric antibiotics<br />
Definition<br />
FEVER OF UNKNOWN ORIGIN<br />
• Fever >101°F (38.5°C) on one or more occasion<br />
• Duration >3 weeks<br />
• No diagnosis despite 1 week of intensive evaluation<br />
Etiologies<br />
• Infection:<br />
Tuberculosis, endocarditis, intra-abdominal abscess,<br />
osteomyelitis, fungal infection, meningitis, hepatitis, CMV,<br />
EBV, Lyme disease, HIV, etc.<br />
• Connective tissue disease:<br />
Temporal arteritis, Polyarteritis nodosa, RA, SLE, etc.