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BUMC Basics.pdf - Anesthesia Home

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58<br />

INFECTIOUS DISEASES<br />

BUGS AND DRUGS<br />

(This is not a comprehensive list, but think of these drugs when<br />

you are dealing with the listed bugs; refer to Sanford Guide<br />

and your prescribing references for treatment doses and<br />

specific clinical scenarios)<br />

Atypical PNA (Chlamydia, Mycoplasma, Legionella)<br />

• Azithromycin (Zithromax)<br />

• Levofloxacin (Levaquin)<br />

Candidemia<br />

• Micafungin (Mycamine)<br />

• Fluconazole (Diflucan)<br />

• Voriconazole (Vfend)<br />

• Amphotericin B<br />

• Liposomal Amphotericin B (AmBisome)<br />

Candiduria<br />

• C. albicans (No chronic foley, has symptoms, +pyuria):<br />

Fluconazole<br />

• C. glabrata (With symptoms): Fluconazole, Amphotericin<br />

B<br />

Chronic foley: Change out foley and monitor (unless<br />

neutropenic)<br />

Good anaerobic coverage:<br />

• Zosyn (and anti-pseudomonal penicillins)<br />

• Merrem (and other carbepenems)<br />

• Clindamycin (anaerobes above the diaphragm) (Cleocin)<br />

• Metronidazole (anaerobes below the diaphragm)<br />

(Flagyl)<br />

MRSA<br />

• Vancomycin<br />

• Linezolid (Zyvox)<br />

• Trimethoprim/Sulfamethoxazole (Bactrim)<br />

• Daptomycin (Cubicin)-not indicated for tx of PNA<br />

• Tigecycline (Tygacil)<br />

• Minocycline (for CA-MRSA)<br />

• Doxycycline (for CA-MRSA)

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