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<strong>BUMC</strong> BASICS


2<br />

TABLE OF CONTENTS<br />

Welcome and General Information 5<br />

Authors: Jenny Duewall, MD and Sara Lindsey, MD<br />

• <strong>BUMC</strong> <strong>Basics</strong><br />

• Intern Cross Cover Cheat Sheet<br />

• Contact List<br />

• Obtaining a Consult at Baylor<br />

• Dictation Guide for Discharge/Death Summaries<br />

• Sample Orders/Order Sets<br />

• Prn’s/Prophylaxis Meds<br />

• Social Work vs. Care Coordinators<br />

• DISPO<br />

CLINICAL SECTIONS<br />

Cardiology 29<br />

Authors: Adam Falcone, MD and Alexi Mantas, MD<br />

• CCU in General<br />

• Acute Coronary Syndrome<br />

• Atrial fibrillation<br />

• Calcium Channel Blockers<br />

• Chest Pain<br />

• EKG<br />

• Heart Failure<br />

• Hypertensive Crisis<br />

• Pulmonary Edema<br />

• Syncope<br />

• Tachycardia<br />

Gastroenterology/Hepatology 47<br />

Authors: Tom Van Dinter, MD and Alexi Mantas, MD<br />

• GI Consults and Groups<br />

• General GI/Liver Topics<br />

• General Gastroenterology<br />

• General Hepatology<br />

• GI Studies<br />

Infectious Diseases 58<br />

Author: Jenny Duewall, MD<br />

• Bugs and Drugs<br />

• Fever in the ICU<br />

• Fever of Unknown Origin<br />

• Pneumonia<br />

• Sepsis<br />

• Tests to Consider Ordering<br />

Neurology 66<br />

Author: Jenny Duewall, MD<br />

• Altered Mental Status<br />

• Brain death exam<br />

• Neuromuscular Emergencies<br />

• Seizures


• Status Epilepticus<br />

• Stroke management<br />

Oncology 73<br />

Author: Troy Neal, MD<br />

• The Acute Leukemic<br />

Palliative Care and Clinical Ethics 77<br />

Author: Troy Neal, MD<br />

Pressor Chart 82<br />

Author: Natalie Norman, MD<br />

Pulmonary 83<br />

Authors: Jenny Duewall, MD and Alexi Mantas, MD<br />

• ARDS<br />

• Asthma/COPD<br />

• Mechanical Ventilation<br />

• Pleural effusion<br />

• Pulmonary embolus<br />

Radiology 97<br />

Author: Sara Lindsey, MD<br />

• Radiology Hints<br />

Renal 101<br />

Author: Jenny Duewall, MD<br />

• Acid/Base Disturbances<br />

• Acute Kidney Injury<br />

• Basic Electrolyte Repletion<br />

• Chronic Kidney Disease<br />

• Hyponatremia<br />

• Oliguia<br />

• Renal Replacement Therapy<br />

OUTPATIENT CLINIC GUIDE 112<br />

Authors: Sophie Esmail, MD and Ryan Jones, MD<br />

• $4 Walmart Rx list<br />

OTHER INFORMATION 120<br />

• Top Ten Intern Tips<br />

• Duewall’s Mnemonics (Author: Jenny Duewall, MD)<br />

• Sustenance/Comfort Food (Author: Sara Lindsey, MD)<br />

• Map<br />

3


Special thanks to the following Attendings who dedicated their<br />

time to edit each section in his or her respective specialties:<br />

4<br />

Manish Assar, MD (cardiology/EP)<br />

Robert Black, MD (pulmonary)<br />

Erin Bowman, MD (radiology)<br />

Micheal Emmett, MD (renal)<br />

Robert Fine, MD (palliative care)<br />

Dion Graybeal, MD (neurology)<br />

Chris Haden, MD (pulmonology)<br />

Houston Holmes, III, MD (oncology)<br />

Louis Sloan, MD (ID)<br />

William Sutker, MD (ID)<br />

Ravi Vallabahn, MD (cardiology)<br />

Special thanks to Kim Miller, editorial assistant, UpToDate, Inc.<br />

EDITOR: Jenny Duewall, MD<br />

CONTRIBUTING AUTHORS:<br />

Jenny Duewall, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Sophie Esmail, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Adam Falcone, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Ryan Jones, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Sara Lindsey, MD, Radiology Resident, <strong>BUMC</strong> Dallas<br />

Alexi Mantas, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Troy Neal, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Natalie Norman, MD, Internal Medicine Resident, <strong>BUMC</strong> Dallas<br />

Tom Van Dinter, MD, Gastroenterology Fellow, <strong>BUMC</strong> Dallas


5<br />

Welcome to Baylor University Medical<br />

Center (<strong>BUMC</strong>)<br />

Welcome to <strong>BUMC</strong>! This book has been assembled by Baylor<br />

residents to make the transition from being a medical student<br />

to an intern as smooth as possible. Although this book has<br />

several helpful hints and is a good reference, please remember<br />

to use your clinical judgment and practice evidence based<br />

medicine using the multiple references and resources you<br />

have available to you.<br />

We look forward to working with you and we know it will be a<br />

great year!<br />

Sincerely,<br />

The <strong>BUMC</strong> Internal Medicine Residents, 2008-2009


6<br />

GENERAL INFORMATION<br />

<strong>BUMC</strong> BASICS<br />

Scheduled rounds:<br />

• Attending rounds: Usually 5 times per week, schedule<br />

determined usually at the beginning of the month<br />

• Morning Report: For R2’s and R3’s, every M,W,F from<br />

7-8 a.m.<br />

Conferences:<br />

• Noon conference daily: Roberts Medical Education<br />

Classroom<br />

• Grand Rounds: Tuesday at 8 a.m. in Beasley Auditorium<br />

• Chief’s Conference: Every Friday at noon in the Truett<br />

Conference Room 8ABC (get lunch from the Truett<br />

Cafeteria or Doctor’s lounge and charge it to the room);<br />

during interview season, chief’s conference is on<br />

Thursdays (interview day) on 17 Roberts and buffet is<br />

served<br />

• Potpourri: During Chief’s conference once monthly:<br />

Cases presented by interns and residents<br />

• Intern/Resident Evaluations/Med Student: Last Friday of<br />

each ward month. Residents and Attendings meet at 7:00<br />

and interns meet at 7:30. It is in a conference room<br />

outside of the Truett cafeteria. Get breakfast and charge it<br />

to the room.<br />

Call schedule:<br />

• On general medicine wards: Call every fifth night.<br />

• On CCU, call every fourth night.<br />

• On electives, no call and no weekends except for select<br />

electives when you may work on Saturday (ie ID).<br />

• On ER, no clinic and no call. You work 12-hour shifts,<br />

7 a.m. to 7 p.m. or 7 p.m. to 7 a.m. in the following format:<br />

3 day shifts, 3 night shifts, 3 days off.<br />

• Float month: No call and no weekends. The Float<br />

resident also usually does not work on holidays, so be<br />

considerate and try not to ask them to cover you on those<br />

days.


7<br />

Rounding on your patients:<br />

• See ICU patients first, then floor patients.<br />

• Update your attending as they request; if not specified<br />

otherwise, update them daily.<br />

• See patients you plan on discharging as early as<br />

possible and notify attending of possible discharge so they<br />

can plan on seeing the patient and evaluate readiness for<br />

discharge.<br />

The following need to be done to complete a<br />

discharge:<br />

• Medical Reconciliation Form updated and signed<br />

• Prescriptions filled out and signed<br />

• You can obtain a 2 week supply (no refills) of<br />

medications for your indigent patients if needed. Fill out<br />

the Rx form for a 2 week supply and write social work<br />

across the top and place with discharge information.<br />

• Discharge instructions with follow-up appointments<br />

(separate form)<br />

• Transfer orders are needed if going to a SNF or long<br />

term care facility<br />

• BIR/BSH have special packets that need to be done<br />

• Write discharge order (to home, SNF, BSH, BIR, etc)<br />

• Dictate patient and keep track of job # (write in the chart<br />

if dictated at time of discharge; keep track separately if<br />

dictated later)<br />

Cross cover and check-out:<br />

• Cross Cover starts after 5 p.m. on weekdays and at<br />

noon on weekends<br />

• Check out on-line: please write down user name and<br />

password at orientation<br />

• Call the cross cover intern and check out any seriously<br />

ill patients<br />

• Try to anticipate what may happen to your patient and<br />

instruct cross cover on how you would like that managed.<br />

Codes:<br />

• While on wards you are on the code team two days prior<br />

to your call day. Wear scrubs when you are on codes, oncall,<br />

and post-call


8<br />

• M-F, Code team runs codes starting at 7 a.m. until your<br />

resident lets you know you are off codes, at which time the<br />

on-call team takes over codes. On Saturday, the on-call<br />

team takes codes from 8 a.m. until 8 a.m. Sunday.<br />

Sunday, the on-call team takes codes from 8 am Sunday<br />

to 7 a.m. Monday.<br />

• The supervising resident runs the code. Medical<br />

students often do chest compressions. Interns will<br />

intubate if needed, run lines, and review the chart and<br />

other responsibilities as needed.<br />

• Simultaneous codes or codes within 30 minutes of one<br />

another: Response to the first code is by the code team.<br />

The on-call ward team should go to the second code. If<br />

there is a third code, one intern from each code team and<br />

on-call team should go to that code. If the code team is<br />

gone and the on-call team is called to a code, a second<br />

code within 30 minutes will be run by the CCU<br />

intern/resident on call.<br />

Procedures:<br />

• The ABIM requires that graduates be proficient in the<br />

procedures listed below. There is no specified number, but<br />

a minimum of 3-5 directly supervised procedures is<br />

considered appropriate.<br />

1. Paracentesis<br />

2. Arterial puncture<br />

3. Arthrocentesis<br />

4. Central line placement<br />

5. Lumbar puncture<br />

6. NG tube<br />

7. Pap smear and endocervical culture<br />

8. Thoracentesis<br />

• All other procedures are not required, but residents often<br />

have the opportunity to do intubation, punch biopsies,<br />

bone marrow biopsies.<br />

• Each time you perform a procedure, take a sticker so<br />

you can record it in new innovations (www.newinnov.com)<br />

in your procedure log.<br />

• You will be supervised by a resident until the resident<br />

feels you are proficient, and then you can perform<br />

procedures unsupervised. As a general rule, you are<br />

supervised for the first 6 months of internship.<br />

• Hints for procedures:<br />

1. Use aseptic technique (cap, mask, gown, gloves,<br />

large sterile drape) for central lines and arterial<br />

lines. Other procedures can be done with sterile


9<br />

2. gloves only. During codes, if emergent central<br />

access is needed, lines are typically placed with<br />

gloves only. These emergent lines should be<br />

replaced using aseptic technique as soon as<br />

possible.<br />

3. DO A TIME OUT AND FILL OUT TIME OUT<br />

FORMS<br />

4. Write a procedure note when you are done.<br />

5. Bone Marrow Biopsy: Call hematology lab and<br />

ask for bone marrow technician about 15 minutes<br />

prior to your planned starting time.<br />

6. IJ and Subclavian TLC: Order a stat pCXR and<br />

review it when it returns to ensure placement and<br />

rule out a pneumothorax<br />

7. Arterial line: Check a-line wave form after a-line<br />

placement<br />

New Innovations (www.new-innov.com):<br />

• On-line system for logging hours, procedures,<br />

evaluations, and reviewing curriculum.<br />

• Hours need to be logged and approved by the last day<br />

of the month.<br />

• If you log more than 80 hours a week or violate any work<br />

rules, this will appear in red and you need to change it to<br />

meet rules.<br />

• Curriculum needs to be reviewed prior to each rotation.<br />

The curriculum assigned to you for you to review will<br />

appear on your front log-in page.<br />

• When you log in at the end of the month, the front log-on<br />

page will have who you will be giving patients to or picking<br />

patients up from if you are coming on and going off<br />

general medicine wards.<br />

• Evaluations of your intern/resident/attending will be<br />

assigned to you at the end of the month and you will<br />

receive an e-mail reminder to sign-on and evaluate the<br />

other members of your team.<br />

Electives: The following electives are required. You need 3<br />

out of 4 or 4 out of 5 weeks of these (ie, no 2 weeks of<br />

vacation in a 4 week block):<br />

• Cardiology: If you are interested in a primarily<br />

outpatient experience, consider Drs. Thomas Andrews,<br />

Stephen Johnston, Charles Gottlich, or Karen Klatte. If you<br />

are interested in inpatient experience, consider Drs.<br />

Jeffrey Schussler, Rafic Berbarie, Ravi Vallabhan, Robert<br />

Stoller, James Choi, Jerold Grodin, or Carlos Velasco.


10<br />

• Dermatology: The office of Drs. Alan Menter and Dan<br />

McCoy, or the office of Dr. Farhad Niroomand.<br />

• Endocrinology: The office of Drs. Zaven Chakmakjian,<br />

Howard Heller, Brian Welch, Raphaelle Vallera, and Neil<br />

Breslau, or for diabetes intensive rotation, Dr. Priscilla<br />

Hollander.<br />

• Gastroenterology: For primarily outpatient experience,<br />

Drs. Angela Carollo, Catherine Yaussy, Christopher Vesy,<br />

Lawrence Schiller, or Charles Richardon. For more<br />

inpatient experience, Drs. Robert Anderson, Daniel<br />

DeMarco, Esmail Elwazir.<br />

• Geriatrics: (only need a minimum of 2 weeks)<br />

• Hematology: Drs. Barry Cooper, Houston Holmes, and<br />

Christopher Maisel<br />

• ID: Drs. Mezegbe Behre, Louis Sloan and Cedrik Spak.<br />

For outpatient/HIV experience, consider Dr. Mark Tribble.<br />

On ID, you work on Saturdays.<br />

• Nephrology: Drs. Fenves, Wiederkehr, Hayes, Tran, or<br />

Hebert.<br />

• Neurology: Coordinated by Dr. Dion Graybeal.<br />

• Oncology: Drs. Claude Denham, Thomas Hutson<br />

(primarily GU), David McCullum (primarily GI), Robert<br />

Mennel, Eric Nadler, John Pippin (primarily breast<br />

malignancy)<br />

• Pulmonary/Critical Care: For outpatient experience,<br />

Drs. Millard or Luterman. For inpatient, Drs. Black,<br />

Haden/Woolley, or Ausloos. You can also do one week<br />

with Black, one with Haden/Woolley, one with Millard, etc.<br />

and customize your experience.<br />

• Rheumatology: Coordinated through Alex Limanni.<br />

• Outpatient: Drs. Dean Dimmitt, William Chritensen,<br />

Aggarwal, Armstrong, Neubach, Sibley.<br />

**The remainder of your electives (2) are your choice.<br />

CCU:<br />

• Call every fourth night.<br />

• Each team member is on call by themselves.<br />

• All patients admitted by the intern are then picked up by<br />

the supervising resident in the morning and they will see<br />

the patients behind you.<br />

• All patients admitted by the resident are distributed to<br />

the interns the next day (the resident does not carry their<br />

own patients, but covers the entire service behind the<br />

interns).


11<br />

• There is one resident and 3 interns until the Spring,<br />

when the team becomes 4 interns.<br />

• Teaching rounds are with a separate CCU attending and<br />

are often daily M-F based on the attending’s preference.<br />

Clinic:<br />

• ½ Day per week on your assigned day<br />

• No clinic during ER month<br />

• No clinic when you are post-call<br />

• If clinic patients are admitted to the hospital, they will be<br />

admitted by teaching, and stay on that team unless the<br />

primary clinic intern/resident is on wards, and then they<br />

will transfer to that service in the am.<br />

• See Clinic guide section.<br />

Vacation:<br />

• 3 weeks total per year. Can be taken as 2 weeks and 1<br />

week or 1 week at a time.<br />

• Cannot be taken during ward, CCU, or float months<br />

(thus you can use it during electives or ER)<br />

• Turn in a form ahead of time (6 weeks if possible). Pick<br />

up a request from Suzanne. She will fax it to the clinic so<br />

they block out your clinic schedule for that time. See<br />

vacation policy/request.<br />

• Maternity leave is 6 weeks. You can combine it with your<br />

vacation for that year for a total of 9 weeks. The caveat is<br />

that you cannot exceed 12 weeks total off during your<br />

residency per the ABIM.<br />

• Paternity leave is 2 weeks.<br />

• Vacation does not roll over from year to year. What you<br />

don’t take is lost.


12<br />

INTERN CROSS-COVER CHEAT SHEET<br />

The following are general suggestions. Indicated medications<br />

are recommended but this sheet does not replace the need to<br />

refer to your own prescribing reference (Epocrates, etc). Not all<br />

medications or suggestions are useful for all patients. Please<br />

use your own clinical judgment.<br />

Patients that you should definitely go see are indicated with<br />

a *. Again, please use your clinical judgment when evaluating<br />

whether or not to see a patient. When in doubt, just go lay eyes<br />

on them.<br />

Altered Mental Status<br />

MOVE STUPID<br />

• Metabolic (hypothyroid, hepatic encephalopathy)<br />

• Oxygen (Hypoxia from PNA, pulm edema, etc)<br />

• Vascular (TIA, CVA, Subdural hematoma)<br />

• Electrolytes (Specifically Na, Ca)<br />

• Seizure<br />

• Trauma<br />

• Uremia<br />

• Porphyria<br />

• Infection (sepsis/meningitis)<br />

• Drugs<br />

Things to do<br />

• Chart to see hospital course<br />

• History to narrow differential<br />

• Physical, esp. neuro exam and vital signs<br />

• If fever, do BCx, UCx, CXR<br />

• Pulse ox with ABG for hypoxia. If CXR shows edema,<br />

give IV Lasix.<br />

• IVF if hypotensive<br />

• CT head to r/o bleed or CVA<br />

• Electrolytes & CBC<br />

• LP if you suspect meningitis<br />

• Lactulose therapy if hepatic encephalopathy: Lactulose<br />

30 g packet PO Q8 hours; titrate to 3-4 BM’s per day<br />

• Start ABX if patient appears ill<br />

• Stabilize seizure with drug therapy (Valium, dilantin,<br />

etc.)


Chest pain<br />

13<br />

DDx to consider<br />

• MI<br />

• Angina<br />

• PE<br />

• Pericarditis<br />

• Musculoskeletal<br />

• Pneumonia<br />

• PTX<br />

• Anxiety (very common)<br />

• Aortic Dissection<br />

• Pleurisy<br />

• Boerhave’s syndrome (ruptured esophagus)<br />

Things to do<br />

• Obtain history to try to elucidate etiology of CP<br />

• Focused Physical<br />

• Evaluate chart to see past history (CAD, etc.)<br />

• EKG after you take history. This will help limit the DDx<br />

above.<br />

• Cardiac enzymes if cardiac cause is considered.<br />

• CXR to look for pneumonia and aortic aneurysm<br />

• ABG for PE and pneumonia<br />

• Pain meds if musculoskeletal<br />

• Mild anxiolytic if anxiety<br />

• 100% O2 by facemask if small PTX, Chest tube if large<br />

PTX (>15%)<br />

If it’s angina, do following:<br />

• EKG first! Make sure it’s not a STEMI. Trend out<br />

CKMB/Troponins.<br />

• Check BP and then give NTG q 5 min until CP relieved.<br />

Make sure nurse checks BP in between each Nitro to<br />

avoid hypotension<br />

• If pt requires more than 3 nitro, give IV morphine 2 mg-4<br />

mg for pain relief. If you are unsuccessful after 20-30 min,<br />

pt will need IV NTG in ICU. Think MONA BASH for<br />

UA/NSTEMI/STEMI: Morphine/Oxygen/Nitro/Aspirin/B-<br />

Blocker/ACE Inhibitor/Statin/Heparin


Fever<br />

14<br />

DDx to consider<br />

• Infection (pneumonia, UTI, etc.)<br />

• PE<br />

• Drug fever<br />

• DVT<br />

• Fungal infection<br />

Things to do<br />

• Take history to try to find source (cough, dysuria, etc.)<br />

• Look through chart to see what has been done (previous<br />

blood cultures, etc.)<br />

• Perform focused physical exam, esp. vital signs<br />

• Do CXR, Blood cultures, Urine culture, sputum culture (if<br />

indicated)<br />

• Start abx only if patient looks ill with broad spectrum<br />

• Refer to cross cover sheet or progress notes for<br />

preference of what to advance antibiotics to if already on<br />

abx (esp neutropenic fever)<br />

Hypotension<br />

DDx<br />

• Sepsis<br />

• Cardiogenic shock<br />

• Adrenal insufficiency<br />

• Hemorrhagic shock<br />

• Volume depletion (overdiuresed)<br />

• Medication<br />

Things to do:<br />

• Try fluid bolus of 1 L NS (less if CHF/3 rd spacing)<br />

• Assess cause<br />

• If septic: volume resuscitate; check cultures; broad abx;<br />

start pressors (levophed) if needed to keep MAP>65<br />

• If Cardiogenic shock: Assess why. Start dopamine or<br />

dobutamine if needed<br />

• If concern for adrenal insufficiency, start stress dose<br />

steroids: Solumedrol 50 mg IV Q6 is a good start<br />

• If hemorrhagic shock: Volume resuscitate with NS and<br />

Blood. Check Hemostasis profile and give platelets/FFP<br />

as needed. If in DIC, give cryo. Determine source of<br />

bleeding and then stat consult for<br />

GI/Surgery/Neurosurgery/etc.<br />

• Hold BP meds, diuretics or reduce if needed


SOB<br />

DDx<br />

• Pneumonia<br />

• PE<br />

• Anxiety<br />

• Pulm edema<br />

• MI<br />

• PTX<br />

15<br />

Check CXR/ABG; O2 protocol; A/A nebs if bronchospasm, IV<br />

Lasix if volume overloaded<br />

Work-up and treat as indicated.<br />

Quick reference guide to targeted therapies<br />

to answer calls:<br />

1. Agitation: Ativan 2 mg IV x one, Haldol 2-4 mg IV/IM<br />

Q6hours prn, or seroquel 12.5-25 mg PO/NG q8hours prn<br />

agitation<br />

2. Anxiety: Ativan 2 mg IV x one<br />

3. Atrial fibrillation with RVR: Assess patient. If necessary,<br />

start on diltiazem gtt for rate control. Primary team can<br />

determine need for anticoagulation in the a.m.<br />

4. Bradycardia: Evaluate the patient and why they are<br />

bradycardic. If no symptoms, rarely need to treat. If<br />

symptoms, try atropine 0.4 mg IVP as needed x 3 doses.<br />

5. Constipation: Colace 100 mg PO Q12, sennakot one tab<br />

PO BID, Miralax 17g in 4-8 oz water QDay to BID until<br />

BM, MOM 30 ml PO Qday or Dulcolax 10 mg PR<br />

suppository Qday; If severe can try Fleet enema if<br />

needed-usually avoid enemas in neutropenic patients<br />

6. Cough: Tessalon perles 100 mg 3 times/day or every 4<br />

hours up to 600 mg/day, Guaifenesin 200-400 mg PO Q4<br />

hours to maximum of 2.3 g/day<br />

7. Diarrhea: First assess cause; If infectious causes are a<br />

concern, do not treat with anti-motility drugs. Do stool<br />

studies and treat underlying condition. Otherwise, can give<br />

Immodium 4 mg, followed by 2 mg after each loose stool,<br />

up to 16 mg/day; if ICU patient, and non-infectious, can try<br />

adding Banana Flakes to Tube Feeds as a bulking agent<br />

8. Electrolyte disturbances (low): See Electrolyte repletion<br />

9. Fever: Tylenol 325-650 mg PO Q4 hours; Abx if needed<br />

10. Gas: Mylicon


16<br />

11. Heart Burn: AOC. Maalox 320 mg PO Q6 hoursor TUMS<br />

1000 mg PO Q6 hours and/or Pepcid 20 mg PO BID or<br />

Protonix 40 mg PO Qday<br />

12. Hyperkalemia: Check EKG; if peaked T waves or<br />

prolonged QRS, give 1-2 amps Ca gluconate IV; then<br />

consider one or more of the following: 10 Units IV insulin<br />

with 1-2 amps D50, 1-2 amps HCO3; 10-20 mg inhaled<br />

albuterol, 40 mg IV Lasix, or hemodialysis if decreased<br />

GFR. If K is trending up and acute tx is not needed, give<br />

kayexalate 30-90 g PO<br />

13. Hypertension: Clonidine 0.1-0.2 mg PO or SL followed by<br />

0.1 mg Q1hour up to a max dose of 0.6 mg; can also try<br />

increasing the oral medication they are on or giving an<br />

extra dose. If IV needed, try labetalol 5 mg IVP every 5<br />

minutes if HR ok with max dose of 20 mg or Hydralazine 5<br />

mg IVP every 15 minutes, max dose 20 mg<br />

14. Insomnia: Ambien 5-10 mg PO Qhs<br />

15. Nausea/Vomiting: Phenergan 12.5-25 mg IV Q4 hours or<br />

Zofran 4-8 mg IV Q8 hours<br />

16. Nasal congestion: Ocean spray nasal one spray in each<br />

nostril Q8 hours, Oxymetazoline 0.05% 2 sprays in each<br />

nostril Q12 hours<br />

17. Pain: Norco 5/325 one to two tabs PO Q6 hours PRN pain<br />

or Morphine 1-2 mg IV Q4 hours; Careful when Rx<br />

Dilaudid. 1.5 mg Dilaudid is equal to 10 mg of IV<br />

Morphine. We tend to under dose morphine and overdose<br />

dilaudid. If adding narcotics, add a bowel regimen. If pain<br />

persists, can also try 25-50 micrograms Fentanyl every 5-<br />

10 minutes prn not to exceed 100 mcg.<br />

18. Positive Blood Culture: If not on antibiotics, start the<br />

following:<br />

Gram positive: Vanc 1 gram IV, then Rx to dose<br />

Gram negative: Zosyn or Merrem<br />

19. Pruritis: Benadryl 25 mg PO Q4 hours<br />

Drips that can be used on the floor<br />

(telemetry) as of 4/2009:<br />

• Diltiazem<br />

• Amiodarone<br />

• Dobutamine<br />

• Dopamine<br />

• Flolan (Epoprostenol)<br />

• Aggrastat (Tirofiban)<br />

• Integrillin (Eptifibatide)<br />

• Reopro (Abciximab)


17<br />

• Heparin<br />

• Lidocaine<br />

• Nitroglycerin for chest pain<br />

• Milrinone<br />

• Procainamide<br />

• Nicardipine


TPC<br />

972-545-4872<br />

Abrar Ahmad 972-451-<br />

3454<br />

Ali Bagheri 972-356-<br />

2754<br />

Thi Cao 972-356-<br />

2765<br />

Roberto Delacruz 972-356-<br />

2756<br />

Mamta Gupta 972-356-<br />

2702<br />

Stephanie Houck 972-356-<br />

2777<br />

Shalita Jones 972-451-<br />

0648<br />

Susan Kohl 972-356-<br />

2766<br />

Aysha Kunju 972-451-<br />

0647<br />

Shamim Lalani 972-356-<br />

2705<br />

Allison Lander 972-356-<br />

0291<br />

Brad Lembcke 972-356-<br />

2768<br />

Steven Lilly 972-451-<br />

4996<br />

Ankit Mehta 972-451-<br />

0346<br />

Manas Mewar 972-356-<br />

2778<br />

Pushpa Pathak 972-451-<br />

0291<br />

Paul Piper 972-356-<br />

2728<br />

Irving Prengler 972-356-<br />

2775<br />

Carolyn Quan 972-356-<br />

2757<br />

Suman Reddy 972-451-<br />

6192<br />

18<br />

CONTACT LIST<br />

Pager Cell Phone<br />

214-557-<br />

5568<br />

972-380-<br />

4994<br />

469-878-<br />

2941<br />

214-707-<br />

3137<br />

214-478-<br />

9416<br />

214-908-<br />

7590<br />

713-530-<br />

9417<br />

972-821-<br />

6599<br />

214-554-<br />

0707<br />

469-831-<br />

8924<br />

214-924-<br />

6244<br />

214-507-<br />

0816<br />

214-957-<br />

3523<br />

817-966-<br />

6255<br />

281-804-<br />

7420<br />

214-536-<br />

6931<br />

469-855-<br />

1272<br />

214-769-<br />

2357<br />

214-914-<br />

8955<br />

214-564-<br />

8516<br />

Med<br />

Provider<br />

214-820-<br />

3000<br />

After hours<br />

214-346-<br />

1494<br />

Cell<br />

Phone<br />

Robert Beard 214-912-<br />

6178<br />

Steven Bray 214-263-<br />

2016<br />

Laura De 469-939-<br />

Moya 5330<br />

Sharmila 214-282-<br />

Dias 6601<br />

Grady 214-564-<br />

Goodwin 2510<br />

Tara 214-418-<br />

Goodwin 4384<br />

Amy Haller 817-879-<br />

8131<br />

Emily Hebert 972-322-<br />

1997<br />

Nichole 469-688-<br />

Johnson 3797<br />

Anita Khetan 214-244-<br />

1435<br />

Rainer 214-244-<br />

Khetan 1413<br />

Roger 214-213-<br />

Khetan 3544<br />

Lisa Luke 214-912-<br />

7852<br />

Andrew 469-878-<br />

Masica 2715<br />

Catherine 972-352-<br />

Raver 1722


19<br />

TPC<br />

(cont’d)<br />

Pager Cell Phone Cardiologists (cont’d)<br />

Samir Sahai<br />

Brett Stauffer<br />

Bach Tran<br />

972-356-<br />

7218<br />

972-356-<br />

2706<br />

972-356-<br />

2703<br />

214-448-<br />

7264<br />

214-282-<br />

6220<br />

214-735-<br />

0039<br />

Heart Place<br />

(cont’d)<br />

Assar (EP)<br />

Berbarie<br />

Pager<br />

214-595-<br />

0131<br />

214-595-<br />

0118<br />

Sue Williams 972-356- 214-906- Donsky, M 214-595-<br />

0292 2578<br />

0105<br />

Radha Yalamachili 972-356- 214-929- Gottlich 214-595-<br />

2704 0653<br />

1607<br />

Cardiologists<br />

Hall 214-595-<br />

2002<br />

CCT<br />

214-824-8721<br />

Pager<br />

Johnson, K 214-595-<br />

0127<br />

Carry 214-657-<br />

Khan 214-595-<br />

3619<br />

0104<br />

Choi 214-657-<br />

Kowal 214-595-<br />

5508<br />

0373<br />

Donsky, A. 214-657-<br />

Kuiper 214-595-<br />

5534<br />

0130<br />

Franklin (EP) 214-657-<br />

Parmar 214-595-<br />

0525<br />

0115<br />

Grayburn 214-657-<br />

Rosenthal 214-595-<br />

6363<br />

1255<br />

Grodin 214-657-<br />

Schussler 214-595-<br />

5859<br />

0126<br />

High 214-657-<br />

Vallabahn 214-595-<br />

6853<br />

0116<br />

Hyland 214-657-<br />

Wells 214-595-<br />

9759<br />

0128<br />

Johnston 214-408-<br />

Wheelan 214-595-<br />

8096<br />

0129<br />

Klatte 214-657-<br />

Wischmeyer 214-595-<br />

7185<br />

0182<br />

Schumacher 214-657-<br />

North TX<br />

0945<br />

Card<br />

214-826-<br />

6044<br />

Pager<br />

Sills 214-410-<br />

Aggarwal 972-326-<br />

2734<br />

1641<br />

Stoler 214-657-<br />

Andrews 972-602-<br />

1998<br />

6312<br />

Yoon 214-657-<br />

Jiminez 972-602-<br />

3319<br />

6061<br />

Heart Place<br />

214-842-2000<br />

Pager<br />

Shelton 972-602-<br />

6311<br />

Anwar 214-595-<br />

Velasco 972-602-<br />

0125<br />

6313


20<br />

Cardiothoracic<br />

Surgeons<br />

Office Pager Gastroenterologists<br />

Cheung 214-821-<br />

3603<br />

214-897-<br />

0014<br />

DHAT<br />

(cont’d)<br />

Office<br />

Hammon 214-841- 214-595- John 214-821-<br />

2000 0108 Hamilton* 5266<br />

Hebeler 214-821- 214-897- D. Mallat** 214-821-<br />

3603 9342<br />

5266<br />

Henry 214-821- 214-897- Yaussy 214-821-<br />

3603 9343<br />

5266<br />

Hoang 214-942- 214-595- Wash Ave Grp<br />

8300 0109<br />

Kourlis 214-821- 214-822- Angela 214-545-<br />

3603 7867 Carollo 3390<br />

Matter 214-841- 214-595- Dan<br />

214-545-<br />

2000 0107 Demarco 3390<br />

Wood 214-827- 214-920- Katherine 214-545-<br />

3890 3030 Little 3390<br />

Colorectal<br />

Surgeons<br />

Office<br />

Daniel Polter 214-545-<br />

3390<br />

Franko, Edward 214-824-<br />

Schiller 214-545-<br />

1730<br />

3390<br />

Jacobson 214-824-<br />

Anderson** 214-821-<br />

1730<br />

5266<br />

Lichliter 214-824-<br />

1730<br />

Liver Consultants of TX<br />

Rodriguez-Ruesga 214-824-<br />

Linsheng 214-820-<br />

1730<br />

Guo<br />

8500<br />

Tulanon 214-824-<br />

Lepe- 214-820-<br />

1730<br />

Suastegui 8500<br />

Dermatologists Office<br />

Jacqueline<br />

O’Leary<br />

214-820-<br />

8500<br />

McCoy 972-386-<br />

Texas Digestive Disease<br />

7546<br />

Consultants<br />

Mentor 972-386-<br />

Esmail 214-818-<br />

7546<br />

Elwazir* 0948<br />

Endocrinologists Office<br />

Greg<br />

Hodges*<br />

214-818-<br />

0948<br />

Welch 214-823-<br />

Bhavani 214-818-<br />

6435<br />

Moparty** 0948<br />

Hollander 214-820-<br />

Charles 214-818-<br />

3466<br />

Richardon 0948<br />

Gastroenterologists<br />

C. Vesy 214-818-<br />

*does ERCP<br />

**ERCP and EUS<br />

0948<br />

DHAT Office<br />

Texas Digestive Health<br />

Consultants<br />

Landry Center Group James<br />

Burdick<br />

214-820-<br />

8899<br />

Blair Connor* 214-821-<br />

5266


21<br />

Gen Surgery Neurologists<br />

Urgent Surgical<br />

Associates<br />

Office<br />

Texas Neurology<br />

214-827-3610<br />

ASV 214-346-1317<br />

El-Feky<br />

Matthew Lovitt 214-821-<br />

1599<br />

Laura Petry 214-821-<br />

1599<br />

Greenfield<br />

Surgical Institute Office Heitzman<br />

Howard Derrick 214-826-<br />

6276<br />

Herzog<br />

Zelig Lieberman 214-826-<br />

6276<br />

Jenevein<br />

John Preskitt 214-826-<br />

6276<br />

Martin<br />

Jill Stephenson 214-826-<br />

6276<br />

Phillips<br />

Chad Tate 214-826-<br />

6276<br />

Shamim<br />

Health TX<br />

Provider Network<br />

Office<br />

Tunnell<br />

G. McKenna 214-820-<br />

Addt’l Office<br />

2050<br />

Neurologists<br />

Henry Randall 214-820-<br />

Romero 214-827-<br />

2050<br />

5525<br />

ID Office<br />

Graybeal 214-820-<br />

4561<br />

Behre 214-823-<br />

2533<br />

Psychiatrists Office<br />

Columbus 214-823-<br />

John 214-824-<br />

2533<br />

Brennan 2273<br />

Sloan 214-823-<br />

Robert 214-522-<br />

2533<br />

Moore 1960<br />

Spak 214-823-<br />

Antonio 214-363-<br />

2533<br />

Roman 2953<br />

Sutker 214-823-<br />

Vladislav 214-824-<br />

2533<br />

Yeganov 9100<br />

Neurosurgeons Office<br />

Pulmonologists (Critical Care<br />

designated with *)<br />

Bidiwala 214-823-<br />

2052<br />

TX Lung Center (214-824-8521)<br />

Doughty 214-820-<br />

8585<br />

Office Pager<br />

Finn 214-823- *Ausloos 214-246- 214-824-<br />

2161<br />

7767 8521<br />

Gray 214-820- *Black 214-246- 214-824-<br />

8585<br />

7765 8521<br />

Michael 214-823- *Brancaccio 214-246- 214-824-<br />

2052<br />

7774 8521<br />

Naftalis 214-820- *Jordan 214-246- 214-824-<br />

8585<br />

7763 8521


22<br />

Pulmonologists Rheum (214-823-6503)<br />

TX Lung Center (cont’d) Chubick<br />

Luterman 214-246- 214-824- Limani<br />

7770 8521<br />

Millard 214-246- 214-820- Himanshu<br />

7775 3500 Patel<br />

TX Pulm Assoc Pager Cell Phone Petrone<br />

*Haden 972-356- 214-370- Sackler<br />

2725 5555<br />

*Woolley 972-356- 214-673- Tehlirian<br />

2776 6298<br />

Addt’l Pulm John Willis<br />

Baird 214-820- 214-798-<br />

1000 8154<br />

Shotwell 214-824- 214-886- Texas Oncology<br />

4412 1119<br />

214-370-1000<br />

Renal Mobile<br />

Hebert 214-587-<br />

7290<br />

Dallas Nephrology Associates<br />

214-820-2350<br />

Urologists Office<br />

Barri Josh Fine 214-826-<br />

6235<br />

Carino Myron Fine 214-826-<br />

6235<br />

Chandrakantan Steven Frost 214-826-<br />

6021<br />

Fazal Goldstein 214-826-<br />

6021<br />

Fenves Schnitzer 214-824-<br />

0171<br />

Fischbach Schoenvogel 214-827-<br />

1602<br />

Gieser Shuford 214-826-<br />

6021<br />

Hays 214-497-<br />

Eric Smith 214-826-<br />

3755<br />

6235<br />

McDonald<br />

Larry Melton<br />

Webster 214-826-<br />

6021<br />

Arthi Rajagopal<br />

Palliative Care (214-<br />

820-7227)<br />

Kim Rice Minn 214-497-<br />

2612<br />

Joris Schuller Pain mgt 214-512-<br />

John Schwartz<br />

nurse 1106<br />

Long Tran Addt’l IM staff<br />

Wiederkehr Ricardo 214-557-<br />

Murillo 5410


23<br />

OBTAINING A CONSULT AT BAYLOR<br />

Obtaining a consult at <strong>BUMC</strong> is different than at a county<br />

system. Rather than consulting a service, you consult a<br />

specific physician within a service, or whoever is taking call for<br />

that physician if it is after hours. Call consults as early in the<br />

day as possible. If you call a consult after 5pm, this implies that<br />

it is emergent.<br />

If you need a consult, first ensure the attending physician<br />

agrees and ask if they have anyone specifically they would like<br />

you to call. Also, review old records and if a physician has<br />

seen the patient previously from a service, re-consult the same<br />

physician or group if that person is not available. Then, refer to<br />

the above list for whom you would like to consult (May not be<br />

all inclusive, but is a start for who to call). When you call, be<br />

sure to have the patient’s name, room number, date of birth,<br />

and pertinent history, exam, and labs.<br />

There are a few ways to consult. The best is to call the<br />

physician’s office or answering service and ask who is taking<br />

new consults for that day/night. Then ask them to be paged<br />

with the information. You can also call the ER, who has a list<br />

for who is on call. If you do not hear back, and you feel it is<br />

appropriate, then page the physician directly. Some physicians<br />

prefer text messages with name and room number, and they<br />

will let you know that when you work with them.<br />

Here are a few specifics regarding particular<br />

consults:<br />

• GI: The hepatologists rotate call every 3 rd night listed<br />

above. Also, if you need an ERCP or EUS, physicians that<br />

do one or both are noted with an asterisk under the GI<br />

contacts. GI Bleeders often require an emergent GI<br />

consult. For more information, see GI section for obtaining<br />

a consult.<br />

• Neurology: There is someone on call M-F now for<br />

neurology. Call page operator to find out who is on call.<br />

• Psychiatry: To obtain a psych consult, you may either<br />

write an order for psych consult, or call the ER and ask<br />

who is on call for Psych and call the office or answering<br />

service to have them paged.<br />

• Pulmonary Critical Care: This consult is required if<br />

your patient is on the ventilator more than 48 hours.


24<br />

• Rheumatology: The patient typically will need to have<br />

insurance to be seen. You can always call for advice over<br />

the telephone.<br />

• Palliative Care: You can write an order for a palliative<br />

care consult or call 2-7227 to speak with someone directly<br />

(always the best option).<br />

• Pain management: If you need assistance with pain<br />

management, palliative care is available.<br />

• Hospice consult: You can write an order for hospice<br />

consult. The hospice nurse will then evaluate the patient<br />

and if appropriate, write orders to convert the patient to<br />

inpatient hospice care and/or begin to work on referrals<br />

with social work to hospice facilities or home hospice. She<br />

will write orders and call you to review them with you for<br />

any orders you may have missed for comfort care.<br />

• Other: Nutrition/Social Work/Care Coordination/<strong>Home</strong><br />

Health/PT/OT/ST/Pastoral care/Recreational Therapy<br />

consults can all be written for in the order section of the<br />

chart. For vanc/gent, there is an automatic pharmacy<br />

consult. If you need pharmacy to renally dose, you can<br />

write for the medication and then write pharmacy to dose.<br />

DICTATION GUIDE<br />

Dial 26008 in-house; 972-980-8955 outside the hospital<br />

Problems/?: 6171<br />

Keypad Commands (same for <strong>BUMC</strong>/BHVH):<br />

1-play 7-fast forward<br />

2-record 8-rewind to beginning<br />

3-short rewind 9- disconnect/job confirmation<br />

4-pause (write down the confirmation<br />

5-next report number)<br />

6-go to end of job<br />

For <strong>BUMC</strong> dictations:<br />

Site ID: 43310<br />

Work type: 20 H&P, 25 D/C summary, 30 consult, 98<br />

outpatient clinic note<br />

• Enter 11 digit MRN<br />

• Press 2, begin dictating after the tone<br />

For BHVH dictations:<br />

Site ID: 43310<br />

Work type: 52 H&P, 53 D/C summary, 55 consult, 56<br />

Radiology


25<br />

• Enter 2 initial zeros and then 9 digit BHVH account<br />

number (begins with V)<br />

• Press 2, begin dictating after the tone<br />

DISCHARE SUMMARY OUTLINE<br />

Attending:<br />

Date of Admission:<br />

Date of Discharge: Tell what facility they were<br />

transferred to if applicable.<br />

Admission Diagnoses:<br />

Discharge Diagnoses:<br />

Procedures/Tests:<br />

Consultants:<br />

Discharge Medications:<br />

Follow-up:<br />

Brief History & Physical:<br />

Summarize the HPI and admission physical exam; it’s helpful<br />

to the next provider if you also briefly review the MHx,<br />

SurgHx, FamHx, Social Hx<br />

Hospital Course: Most people organize this as a numbered<br />

problem list. Mention the suspected etiology (CHF from<br />

medication noncompliance, hypokalemia secondary to<br />

diuretics, etc.) and explain what work-up, testing and<br />

treatment was performed for each issue. Mention any studies<br />

that are pending at the time of discharge. For simple admits<br />

or for death notes, you can summarize the hospital course in<br />

paragraph format.<br />

MEDICAL RECORDS<br />

Located in the basement of Jonsson. Access WebESA to<br />

edit/review your dictations & electronically sign your charts<br />

either in Medical Records or via the EMR (link on the left).<br />

You have to keep up-to-date with your dictations/charts or you<br />

lose your $50 monthly meal money and get yourself (and<br />

possibly your attending) put on the “B list.” It’s painful …<br />

made better by the giant cookies and snacks waiting for you<br />

in Medical Records.<br />

ADMISSION ORDERS<br />

1. Admit to floor/ICU/telemetry<br />

2. Attending: Dr.<br />

3. R1—Dr. xxx—call 1st<br />

R2/3—Dr. xxx<br />

4. Service: Medicine teaching/CCU teaching


26<br />

5. Diagnosis:<br />

6. Condition: Stable/fair/critical<br />

7. Vitals: per floor/ICU protocol<br />

8. Allergy:<br />

9. Diet: regular/ADA/Heart Healthy/clear liquids/full<br />

liquids/NPO<br />

10. Ins/Outs:<br />

11. Meds:<br />

12. IVF:<br />

13. Labs for AM:<br />

14. Labs for now:<br />

15. Activity:<br />

16. Code Status: Full, DNR/DNI<br />

17. Call HO (house officer) for T>100.4, SBP >170 or 120 or


27<br />

• Albuterol/Atrovent nebulizer Q6 hours prn<br />

• Benadryl 25 mg PO Q4 hours prn pruritus<br />

• Potassium Protocol (cannot use protocol if Cr>1.5,<br />

wt80)<br />

• Oxygen Protocol<br />

PROPHYLAXIS MEDS<br />

• Pepcid 20 mg po BID OR Protonix 40 mg po qday<br />

• Lovenox 40 mg SC qday (if renal function okay) OR<br />

Heparin 5000 units SC TID<br />

SOCIAL WORK VS CARE COORDINATORS<br />

Social Work:<br />

• SNF, LTAC, extended care outside of Baylor, hospice<br />

(in or outpatient)<br />

• Ambulance transport<br />

• Protective Services<br />

• Family Locating<br />

• Transportation<br />

• Crisis Intervention<br />

• Physical Needs (places to stay, vouchers, parking, etc)<br />

• PCP referrals<br />

Care Coordinators:<br />

• <strong>Home</strong> Health Care Referrals<br />

• Dallas Medical Examiner<br />

• BIR Referrals<br />

• VA/Parkland Referrals<br />

• Liason to payer/utilization management<br />

DISPO<br />

(ie, where the pt goes when they get off your service)<br />

• <strong>Home</strong><br />

Can arrange home health care, home PT/OT if<br />

needed<br />

• SNF (skilled nursing facility, pronounced “sniff”)<br />

Must require the skills of a qualified technician or<br />

professional (RN, PT, OT, ST, etc)<br />

• LTAC (long term acute care, pronounced “L-tach”)<br />

Must have 2+ complex needs to qualify<br />

• Acute Rehab<br />

Must be medically stable & able to participate in 3<br />

hours of therapy/day; must require 24 hr nursing<br />

supervision and physician care which demonstrates


28<br />

“necessity” for inpatient care; must have viable<br />

disposition to return to community upon discharge<br />

• BIR (Baylor Institute for Rehab)<br />

<strong>BUMC</strong> long term acute care; write “transfer to BIR<br />

when bed available” (no separate orders)<br />

• BSH (Baylor Specialty Hospital)<br />

<strong>BUMC</strong> physical rehabilitation hospital; just complete<br />

the BSH order set prior to transfer<br />

• NH (nursing home)<br />

• Hospice (end of life care)<br />

Must be terminally ill with life expectancy < 6months;<br />

hospice can be at home, NH, hospital or freestanding<br />

hospice facility; note: inpatient hospice is for an<br />

actively dying patient<br />

The patient’s funding (Medicaire/Medicaid/private) affects their<br />

options; the social workers and care coordinators can help you<br />

figure out each patient’s options. “Charity beds” are available<br />

at BIR and BSH on a case-by-case basis. You can write an<br />

order for a “BIR [or BSH] consult” and the liaison will review the<br />

pt’s case.


29<br />

CARDIOLOGY<br />

CCU IN GENERAL<br />

You are typically called for the following patients:<br />

• Patient in the cath lab having a stent placed 2/2 STEMI:<br />

You can go to the cath lab and watch the cath, or you may not<br />

meet them until recovery or when they get to the CCU. These<br />

patients typically come out with post-cath orders filled out by<br />

the cardiologist or fellow, but you sometimes also fill these out<br />

if you are there early in the process. You are then responsible<br />

for getting the HPI and adding additional orders/meds.<br />

• Patient transferring from OSH 2/2 MI s/p lytics: These<br />

patients will need orders as below for ACS, but no GpIIb/IIIa<br />

inhibitors. You will likely do H&P and initial orders and then talk<br />

with the cardiologist then or in the A.M. (if the patient comes in<br />

the night) whether they need to go to cath.<br />

• Patients in the ER with UA/NSTEMI: See management<br />

below<br />

• Decompensated CHF patients with pulmonary edema in<br />

the ER: Follow CHF order set and treat pulmonary edema as<br />

below in pulmonary edema section.<br />

ACUTE CORONARY SYNDROME<br />

Stable Angina: Chest pain resulting from imbalance of<br />

oxygen supply and demand to cardiac<br />

tissue. Usually happens at the same<br />

frequency, intensity, and duration. Most<br />

common cause is CAD; other causes include<br />

aortic valvular disease, HCM, and coronary<br />

artery spasm. This is due to a stable plaque.<br />

UA/NSTEMI: New onset of severe angina, angina at rest<br />

or with minimal activity, or recent increase in<br />

frequency and or intensity of stable angina. If<br />

patient has positive cardiac markers<br />

(necrosis) without ST elevation, then this is<br />

defined as NSTEMI. This is due to a partially<br />

occluding thrombus.


30<br />

STEMI: Complete occlusion of coronary artery by<br />

thrombus resulting in ST elevation on EKG.<br />

Progression — Stable plaque-unstable plaque-plaque<br />

rupture-UA/NSTEMI (partial occlusion)-microemboli-STEMI<br />

(complete occlusion)<br />

Orders — For ACS: Think MONA BASH (Morphine, Oxygen,<br />

Nitroglycerin, Aspirin, B-blocker, Statin, Heparin)<br />

Meds:<br />

1. Morphine 2 to 4 mg IV Q4 hours prn chest pain<br />

2. Oxygen per protocol to keep SpO2>92%<br />

3. Nitroglycerin 0.4 mg SL Q3-5 minutes x 3 doses prn<br />

chest pain<br />

4. ASA 325 mg PO Qday<br />

5. BBlocker: Can use coreg 3.125 mg to 6.25 mg PO<br />

BID and increase as needed: write parameters on BP<br />

meds (hold for SBP


31<br />

Unstable Angina/NSTEMI<br />

• Can use history, physical exam, and TIMI risk score to<br />

stratify.<br />

• TIMI risk score will help dictate conservative versus invasive<br />

strategy.<br />

**Get Cardiology on case soon if not admitted by a<br />

cardiologist!<br />

Tests — Chest X ray, EKG, Echo (non emergent) and cardiac<br />

enzymes (Troponin and CKMB)<br />

EKG: Will show ST depression, T wave inversion, or<br />

nonspecific changes.<br />

Treatment — Revolves around three keys: (1) anti-ischemic<br />

therapy, (2) antiplatelet therapy, and (3) anticoagulation.<br />

• Anti-Ischemic Therapy: Nitrates, Beta blockers (don’t<br />

use if hypotensive, wheezing, bradycardia), Calcium<br />

channel blockers (nondihydropyridines, if can’t use beta<br />

blockers), morphine, and oxygen.<br />

• Antiplatelet Therapy: ASA, Plavix (load with 300 or<br />

600mg, don’t use if suspect going to CABG), GP IIB/IIIa<br />

inhibitors (pts with >3 TIMI risk score and positive cardiac<br />

enzymes)<br />

• Anticoagulation: UFH (bolus and wt. based titrate for<br />

aPTT of 50-70). Use bivalirudin if patient has heparin<br />

induced thrombocytopenia.<br />

Low Risk: Negative cardiac enzymes, no ST depression,<br />

TIMI score 3. Use GPIIb/IIIa and will need angiography<br />

with in 24-48 hours.<br />

STEMI<br />

• Immediately call cardiologist on call and activate cath lab.<br />

• Will have ST elevation in >2 leads with reciprocal changes or<br />

new onset of LBBB.


32<br />

EKG Artery Areas of Complications<br />

Leads<br />

Damage<br />

V1-V2 LAD septal Septum, Nodal block and<br />

branch bundles of his BBB<br />

V3-V4 LAD diag. Ant. Wall LV LV dysfunc,<br />

branch<br />

CHF, BBB, AVB<br />

V5-V6, + I & Circumflex High lateral LV dysfunc, AVB<br />

AVL<br />

wall LV<br />

II, III, AVF RCA Post. Inf. Wall, post. Hypotension<br />

Descending Wall LV sensitivity to<br />

branch<br />

NTG and<br />

Morphine<br />

V4R (II, III, RCA proximal RV, inferior Hypotension, A<br />

AVF)<br />

branch and posterior<br />

wall<br />

fib/flutter,<br />

V1-V4 Circumflex or Posterior wall LV dysfunction<br />

Depression RCA<br />

• Need emergent fibrinolysis versus PCI. At Baylor, PCI is<br />

done, so you need to activate cath lab. **TIME IS TISSUE.<br />

• We have STEMI protocol at <strong>BUMC</strong>. Door to balloon time 60), free wall rupture (surgery), VSD<br />

(surgery), papillary muscle rupture (new onset of holosystolic<br />

murmur, get stat Echo and use diurectics, vasodilators, IABP,<br />

& surgery), A fib, VT/VF (in first 48 hours, often due to<br />

myocardial healing and can consider no treatment even in<br />

sustained; need to treat if symptomatic; more likely to treat if<br />

monomorphic, fast rate->200-, or low EF; if occurs after more<br />

than 48 hours from the MI, needs an ICD as mortality is >20%<br />

in next year from an arrhythmia), LV thrombus (anticoagulate),<br />

ventricular aneurysm (persistent ST elev.), ventricular<br />

pseudoaneurysm (surgery), pericarditis (1-4 days post MI, tx.<br />

NSAIDS), and Dressler’s syndrome (2-10 wks post MI, tx.<br />

NSAIDS)


33<br />

Post PCI Complications — In your note following PCI, be<br />

sure to comment on the following:<br />

1. Vascular access site (check for hematoma)<br />

2. Distal pulses<br />

3. Any signs of cholesterol emboli syndrome (any livedo<br />

pattern or toe necrosis)<br />

4. H&H, Tele monitoring, Creatinine<br />

5. Watch for the following complications:<br />

• Hematoma/Bleeding: Manual compression,<br />

reverse/stop anticoagulation<br />

• Retroperitoneal bleed (hypotension,<br />

abdominal/flank pain, dropping H&H): Stat CT<br />

abd/pelvis if concern for retroperitoneal bleed and<br />

stable enough to go. Blood, fluid, and pressors,<br />

and call cardiologist immediately. May need<br />

vascular consult.<br />

• Pseudoanerysm: triad of pain, expansile mass,<br />

systolic bruit; Dx with U/S; treat with compression<br />

or surgical repair<br />

• Contrast induced Acute Kidney Injury:<br />

Manifests within 24 hours; peaks at 3-5 days;<br />

Pre-hydrate patients to prevent kidney injury with<br />

IV fluids. Continue IVF’s after cath to protect<br />

kidneys<br />

• Cholesterol emboli syndrome: Renal failure,<br />

eos in urine, mesenteric ischemia, toe necrosis,<br />

Hollenhorst plaques in retinal arteries<br />

• Stent thrombosis: Urgent return to cath lab<br />

• In-stent restenosis (months after PCI)<br />

Prognosis<br />

Killip Class (on admission):<br />

Class Signs Mortality<br />

I No CHF 5%<br />

II S3, and/or crackles of lung<br />

exam<br />

17%<br />

III Pulmonary edema 30-40%<br />

IV Cardiogenic shock 60-80%


34<br />

Post MI and Discharge Medications:<br />

1. Post MI ECHO<br />

2. Meds: ASA, Plavix, Beta Blockers, statins,<br />

ACEI/ARB’s, NTG (PRN), aldosterone (if LVF


35<br />

function, elevated troponin T is still a predictor of cardiac<br />

events across all creatinine clearance levels)<br />

ATRIAL FIBRILLATION<br />

Classification — Paroxysmal (self terminating < 7 days,<br />

usually 7 days), and permanent (typically<br />

greater than a year or cardioversion failed/not attempted)<br />

Causes:<br />

• “I SMART CHAP”<br />

• Infection/Sepsis<br />

• Surgery (post CABG, post valve surgery)<br />

• Medication (theophylline, caffeine, etc)<br />

• Atherosclerotic Heart Disease<br />

• Rheumatic Heart Disease (MS, MR)<br />

• Thyrotoxicosis<br />

• Congenital Heart Disease (ASD)<br />

• Hypertension<br />

• Alcohol (dilated cardiomyopathy, holiday heart<br />

syndrome)<br />

• Pulmonary (PE, PNA, Hypoxia, COPD)<br />

Evaluation — H&P, EKG, CBC, CMP, TSH, Drug screen (if<br />

indicated), chest X-ray, TTE, cardiac enzymes.<br />

Treatment — Treatment revolves around rate control,<br />

rhythm control, and deciding on needed anticoagulation.<br />

**IF PT IS UNSTABLE, THEY NEED EMERGENT<br />

CARDIOVERSION**<br />

Rate Control: Goal HR 60-80’s<br />

• B blockers (metoprolol, coreg)<br />

• Digoxin (good for people with borderline BP's as<br />

does not lower BP; watch dig levels)<br />

• CaCh Blockers (diltiazem drip vs PO verapamil). If<br />

maintained on a diltiazem drip, can add up total mg in<br />

24 hour period, and then give them this amount in<br />

Diltiazem ER P.O. Give first oral dose then overlap<br />

with drip for 3 hours.<br />

Anticoagulation: CHADS2 Score: C (CHF), H (HTN), A<br />

(age ≥75), D (DM), S (stroke, TIA, and most add systemic<br />

embolic event).


36<br />

Get 1 point for each and 2 points for stroke or TIA.<br />

0 Points: ASA 325mg q day alone<br />

1 point: ASA 325mg q day or Coumadin (INR 2-3)<br />

2 or greater points: Coumadin (INR 2-3)<br />

Rhythm Control: Electrical or Pharmacologic cardioversion<br />

• Electrical:<br />

- 48 hours, and has been with INR 2.0 to 3.0 for<br />

3 weeks, no need for TEE. If INR not therapeutic,<br />

need IV heparin or SQ lovenox before TEE &<br />

then DC CV<br />

- If LA thrombus, anticoagulate >8 weeks, then<br />

cardiovert<br />

- If pt. is cardioverted and they were in AFIB<br />

greater than 48 hours they will need to be anticoagulated<br />

with Coumadin for at least 4 weeks.<br />

(High likelihood of reoccurrence).<br />

• Pharmacologic choices: Procainamide, ibutilide,<br />

flecainide, propafenone, amiodarone (watch PFT’s,<br />

TFT’s, LFT’s), sotalol (watch QTc), Dofetilide (watch<br />

QTc, no Bblocker effect so good for patients who<br />

can’t tolerate amiodarone or sotalol, but need special<br />

prescribing privileges.)<br />

CALCIUM CHANNEL BLOCKERS<br />

Class/Drug AV<br />

Blockade<br />

Vasodilation BP<br />

Control<br />

Dihydropyridine None +++ +++<br />

Verapamil +++ + +<br />

Diltiazem ++ ++ +<br />

CHEST PAIN<br />

Can be typical, atypical, or non-cardiogenic chest pain.<br />

Assess chest pain — If has chest pain (1 point), if occurs<br />

with exertion (1 point), and relieved with rest or NTG (1 point)


37<br />

**0-1 point non-cardiogenic, 2 points atypical chest pain, 3<br />

points typical chest pain.<br />

Cardiogenic causes: Angina, MI, pericarditis,<br />

myocarditis, aortic dissection<br />

Pulmonary Causes: PNA, pleuritis, pneumothorax,<br />

PE, Pulmonary HTN<br />

GI Causes: Reflux, esophageal spasm,<br />

Mallory-Weiss Tear, Boerhaves,<br />

PUD, pancreatitis, biliary<br />

Muscle/other causes: Costochondritis, osteoarthritis,<br />

shingles, and anxiety<br />

Initial work up: History and PE going to dictate your workup,<br />

but good places to start are EKG, chest x-ray, and<br />

troponin/CKMB<br />

Ongoing chest pain 2/2 ACS: Can start on Nitroglycerin gtt at<br />

10 mcg/min and then titrate up (side effect=HA)<br />

EKG<br />

Ventricular Rate<br />

• Count large boxes between R waves:<br />

300,150,100,75,60,50. Can also count # of beats on 6 sec<br />

strip and multiply x 10<br />

• Conduction rates of specialized tissue:<br />

20-40 Ventricular rhythm<br />

40-60 Junctional rhythm<br />

60-100 Normal sinus rhythm<br />

100-150 Sinus tachycardia<br />

150-250 Supraventricular/Ventricular<br />

tachycardias<br />

Rhythm<br />

• Sinus (upright P in I and aVF and negative in aVR<br />

suggesting that the direction of atrial depolarization is from<br />

SA to AV node, there is a P wave before each QRS, the P<br />

wave marches out w/ calipers, the P wave has the same<br />

morphology)<br />

• Junctional (no P wave but still narrow QRS; rate 40-60)<br />

• Idioventricular (no P wave and QRS is wide; rate 20-40)


38<br />

Axis<br />

• Normal (-30 to +90): upright QRS in I and aVF<br />

• RAD (+90 to +180): negative in I and positive in aVF<br />

• LAD (-30 to -120): positive in I and negative in aVF<br />

• Extreme RAD (-120 to +180): if negative in I and II, then<br />

you have either extreme LAD or RAD<br />

Intervals<br />

• PR interval: Normal 120 to 200 msec<br />

- Shortened: Think WPW or Lown-Ganong-Levine<br />

syndrome<br />

- Prolonged (>200 msec), think:<br />

• 1° AV Block: Prolonged PR interval >200 msec;<br />

QRS follows all p waves<br />

• 2° AV Mobitz Type I (Wenckebach): prolonged<br />

PR interval that gets progressively longer<br />

followed by a dropped QRS; Mobitz Type II: PR<br />

interval that are constant with intermittently<br />

dropped QRS complexes<br />

• 3° AV Block: Atria and ventricles acting<br />

independently; atrial rate>ventricular rate<br />

• QRS interval: normal is 120msec Deep S RSR’<br />

(L Heart if < then<br />

Dz) “incomplete”<br />

RBBB >120msec RSR’ Large S Slurring<br />

(R Heart if < then<br />

of S<br />

Dz) “incomplete”<br />

L Anterior Fascicular Block (LAFB) aka Hemiblock<br />

LAD + QRS


39<br />

• Erythromycin<br />

• Phenothiazines<br />

- Short QTc is caused by hyperkalemia,<br />

hypermagnesemia, and hypercalcemia.<br />

Hypertrophy and Enlargement<br />

• P (atrial depolarization)<br />

II (nl: 3mm<br />

more Negative (>1mm)<br />

RAE Tall >2.5mm More Positive Peak<br />

>1.5mm<br />

• Ventricular hypertrophy<br />

- LVH: kissing waves, S in V1 + R in V5/6 >35mm, R<br />

in aVL >11mm, or R in V4-V6 >25mm<br />

- RVH: tall R wave in V1 with an amplitude > 7 mm or<br />

R wave in lead V1 + the amplitude of the S wave in<br />

lead V6 > 10 mm.<br />

Signs of ischemia/infarction<br />

• ST Depression: Indicates ischemia; significant if the ST<br />

segment is depressed by 1 mm or more<br />

• T-Wave Inversion (TWI): Can also indicate ischemia but<br />

can be due to LVH with strain, abdominal pain,<br />

medications (digitalis), and CNS hemorrhage.<br />

• ST elevation (STE): indicates transmural infarction<br />

(injury); significant elevation is 1 mm in the limb leads and<br />

2 mm in the precordial leads.<br />

• Q wave: indicates muscle death from a lack of blood<br />

supply. A Q wave is considered pathologic if it is 1 small<br />

box wide and deeper than 25% of the R wave. “Q’s in III<br />

are free”.<br />

Other<br />

• Early repolarization: Concave “Happy” STE (early repol<br />

which is seen in young pts and those w/ LVH, pericarditis,<br />

myocarditis, head contusion, PTX)<br />

• Low Voltage (


40<br />

sleeping, EKG: ST elevation and TWI in V1-3 in setting of<br />

RBBB)<br />

• Hypothermia (Osborn Wave = small wave at J point)<br />

• Pulmonary Embolism (R heart strain signified by<br />

RBBB/RAD/RVH/RAE, sinus tachycardia, S1Q3T3:broad<br />

S in I, Q wave in III, inverted T in III)<br />

• Pericarditis (PR depression in II, diffuse STE)<br />

• COPD (R heart strain like above + Low Voltage of<br />

Precordial Leads only, Prominent P Waves)<br />

• Digitalis (therapeutic: sloping downward ST, T<br />

depressed or inverted, short QT) vs (Excess: SA Block,<br />

PAT w/ Block, AV Block, AV Dissociation) vs (Toxicity:<br />

Afib, JT, VT, multiple PVC, VFib)<br />

HEART FAILURE<br />

The heart cannot produce output to match the metabolic<br />

demands of the body.<br />

Systolic Dysfunction: Decreased EF, pump failure<br />

Diastolic Dysfunction: Preserved EF, but impaired<br />

relaxation of the ventricle.<br />

Causes:<br />

• CAD/MI<br />

• HTN<br />

• Valvular Disease: AS, AR, and MR<br />

• Arrhythmias: Long standing tachycardias<br />

• Metabolic/Toxic/Drugs: Beriberi, Pagets disease,<br />

chemo drugs, alcohol, thyroid<br />

• Infectious: Sepsis, coxsackie virus, chagas disease, etc<br />

• Pericardial Disease<br />

• Infiltrative Disease of Myocardium: Amyloid, sarcoid,<br />

and hemochromatosis<br />

Initial work up — H&P, CBC, CMP, EKG, chest X-ray,<br />

cardiac enzymes, TSH, TTE, if new onset +/- inpatient<br />

coronary angiography<br />

Functional classification:<br />

NYHA Class I: Symptomatic only with greater than<br />

ordinary activity.<br />

NYHA Class II: Symptomatic with ordinary activity.<br />

NYHA Class III: Symptomatic with minimal activity.<br />

NYHA Class IV: Symptomatic at rest.


41<br />

Therapy — Therapy is guided by stage of heart failure. For<br />

acute HF relief refer to pulmonary edema section.<br />

Stage Characteristics Therapy<br />

A No symptoms, no<br />

structural<br />

disease, just risk<br />

factors. (CAD,<br />

DM, HTN,<br />

cardiotoxic<br />

exposures)<br />

B Abnl. LVF,<br />

structural heart<br />

disease, previous<br />

MI, but<br />

asymptomatic.<br />

C Structural heart<br />

disease and<br />

symptomatic HF.<br />

Life style<br />

modifications, treat<br />

HTN, treat HLD, and<br />

control DM.<br />

ACEI: if HTN, DM, &<br />

PVD are present.<br />

All of stage A therapy,<br />

plus ACEI and beta<br />

blocker<br />

All stage’s A&B, plus<br />

diuretics, Na+ restrict,<br />

aldactone, AICD, BiV<br />

pacing,<br />

nitrates/hydralazine,<br />

and digoxin<br />

D Refractory HF All stages A,B, & C,<br />

plus LVAD, heart<br />

transplant, IV<br />

ionotropes, and<br />

hospice<br />

In the chart if you state that a person has heart failure you<br />

need to record EF, state if it’s diastolic or systolic dysfunction,<br />

and if it is acute or chronic.<br />

HYPERTENSIVE CRISIS<br />

Hypertensive Urgency: SBP >180 or DBP> 120 with<br />

minimal or no target end organ<br />

damage.<br />

Hypertensive Emergency: Acute rise in BP with end organ<br />

damage noted. Neurologic<br />

(hemorrhages, encephalopathy,<br />

papilledema), cardiac (ACS, HF,<br />

aortic dissection), or renal<br />

(proteinuria, hematuria, renal<br />

failure).


42<br />

Causes:<br />

• Progression of HTN<br />

• Medical noncompliance on BP meds<br />

• Progression of renal disease<br />

• Glomerulonephritis<br />

• Preeclampsia<br />

• Scleroderma<br />

• Pheochromocytoma<br />

• Cocaine/Amphetamines<br />

• MAO inhibitors + tyramine rich foods<br />

Treatment:<br />

• Hypertensive Urgency: Decrease MAP by 25% over<br />

hours using oral agents. Beta blockers, calcium channel<br />

blockers, hydralazine and ACEI. Then start BP regimen to<br />

get WNL.<br />

• Hypertensive Emergency: Decrease MAP by


43<br />

Nitroglycerine (Onset in 2-5 min) 5-100 mcg/hr<br />

(Tridyl): IV and titrate to keep desired MAP<br />

**Specific Conditions and Agents to Use:<br />

• In HTN Encephalopathy, use Nitroprusside and if that<br />

fails then Beta-Blocker or Nicardipine<br />

• In Subarachnoid Hemorrhage, use Nimodipine and if<br />

that fails then Beta-Blocker or Nicardipine<br />

• In CVA or aortic dissection, use Beta-Blocker and if that<br />

fails then Nitroprusside<br />

• In ARF, use Nicardipine and if that fails then Fenoldopan<br />

• In Cardiac Ischemia use Nitroglycerine + Beta-Blocker<br />

and if that fails then Nitroprusside<br />

• In post surgical patient, use Fenoldopam.<br />

PULMONARY EDEMA<br />

Causes — Revolves around three major organ systems<br />

Cardiogenic: Valvular abnormalities (acute MR, acute<br />

AR), MI/CAD, new onset arrhythmias,<br />

severe HTN, diastolic/systolic<br />

dysfunction w/ volume overloaded state,<br />

and pericardial dz. Usually must have<br />

some underlying cardiac disease<br />

(systolic/diastolic dysfunction) and<br />

another one of the other causes<br />

compounded to put pt. into cardiogenic<br />

pulmonary edema. Will have elevated<br />

PCWP >18mmHg.<br />

Pulmonary: Disruption of alveolocapillary barrier<br />

dysfunction (ARDS, trauma, aspiration,<br />

PE, and goodpastures); PCWP<br />


44<br />

Start out with aggressive diuretic therapy over first 24 hours,<br />

and reevaluate diuretic therapy every 24 hours. Oxygenation:<br />

start with nasal canula; then may need to advance to BIPAP,<br />

or even intubation if can’t keep adequate oxygenation (PaO2<br />

>60mmHg).<br />

SYNCOPE<br />

Sudden and brief loss of consciousness due to cerebral<br />

hypoperfusion<br />

Causes:<br />

• Neurocardiogenic: “Vasovagal syncope” 2/2 increased<br />

vagal tone<br />

• Orthostatic Hypotension: Hypovolemia, diuretic therapy,<br />

vasodilators, autonomic neuropathy.<br />

• Cardiovascular: Usually has a sudden onset and<br />

recovery<br />

1) Arrhythmias: Bradycardia (AVB, SSS),<br />

Tachycardia (VT, SVT)<br />

2) Mechanical: Endocardial, Myocardial,<br />

Pericardial, or Vascular<br />

• Neurological:Seizure, TIA/CVA (rare), vertebrobasilar<br />

insufficiency, and migraines.<br />

• Misc: Hypoxia, anemia, hypoglycemia.<br />

Work up:<br />

• In this Case H&P are the most important part of work up.<br />

• What was pt. doing prior to episode, how did they feel<br />

(palpitations, flushed, light headed, etc.), was it witnessed,<br />

did they lose consciousness, how long did they lose<br />

consciousness, was there seizure activity, previous<br />

episodes, PMHx important, Meds pt. taking, etc.<br />

• H&P will guide causes, work up and therapy.<br />

• Labs/Studies: EKG, CBC, CMP, check orthostatic vitals,<br />

u/s Doppler lower ext (usually not indicated), u/s carotids,<br />

TTE, CT scan head (usually not indicated but usually done<br />

in ER when pt. first comes in), EEG (if seizure is highly<br />

suspected).<br />

• Admit pt to telemetry bed, hold meds that could cause<br />

syncope.<br />

• A lot of times specific cause will not be found; try to<br />

optimize meds to avoid recurrence.


45<br />

Treatment:<br />

• Vasovagal: Recognize prodrome and take supine<br />

position when prodrome comes on. Increase salt/ fluid<br />

intake. Medications include beta-blocker, prozac,<br />

midodrine, fluorinef.<br />

• Bradycardia: Hold AVB agents, may need pacemaker. If<br />

SSS with tachy-brady, may need additional of AVN<br />

ablation.<br />

• Tachycardia: If VT/VF, may need AICD.<br />

• Valvular Disease: Surgery to correct.<br />

• Hypovolemia: Correct volume status, d/c diuretics, d/c<br />

vasodilator drugs.<br />

1) SinusTachy.<br />

(P – in AVR<br />

and + I&AVF)<br />

2) Atrial Flutter<br />

w/ 2:1 Block<br />

3) Atrial Tach.<br />

4) AVRT<br />

5)AVNRT<br />

TACHYCARDIA<br />

QRS<<br />

0.12ms<br />

Narrow Complex<br />

Regular Irregular<br />

1) Atrial<br />

Fib.<br />

2) Aflutter<br />

with<br />

variable<br />

block<br />

3) Multi<br />

focal atrial<br />

tach.<br />

Tachycardia<br />

QRS<br />

>0.12<br />

Regular<br />

1) V-Tach<br />

2) SVT<br />

with<br />

aberrant<br />

pathway<br />

(WPW).<br />

Wide Complex<br />

Irregular<br />

1) A-fib with<br />

aberrant<br />

pathway.<br />

2) A-fib with<br />

WPW<br />

3) Torsades<br />

Regular Narrow tachycardia — Can use adenosine to<br />

help differentiate. Ventricular response with Aflutter & Atrial<br />

tachycardia will transiently slow down with adenosine. AVRT &<br />

AVNRT will typically convert to SR with adenosine.


46<br />

Multi Focal atrial tachycardia — RR interval variable<br />

making rhythm irregular looking. There will be at least 3<br />

morphologically different p waves with rate greater than 100.<br />

Favors V-tachycardia on EKG — 1) AV dissociation. 2) if<br />

QRS >0.16. 3) Fusion/capture beats 4) Concordance (all R<br />

waves positive or negative). 5) Hx of structural heart dz. 6)<br />

RBBB in V1 7) look for negative in V6 8) NW axis-extreme right<br />

axis deviation (neg in I and aVF)


47<br />

GI/HEPATOLOGY<br />

GI CONSULTS AND GROUPS<br />

Digestive Health Associates of Texas (DHAT)<br />

(Ten gastroenterologists in two different call group<br />

arrangements)<br />

Washington Avenue Group (214) 545-3990<br />

Daniel Polter, MD<br />

Daniel DeMarco, MD<br />

Cathy Little, MD<br />

Angela Carollo, MD<br />

Lawrence Schiller, MD<br />

Landry center group (214) 821-5266<br />

J. Kent Hamilton, MD*<br />

Blair Conner, MD*<br />

Robert Anderson, MD**<br />

Damian Mallat, MD**<br />

Catherine Yaussy, MD<br />

Texas Digestive Disease Consultants (TDDC)<br />

(214) 820-4490<br />

Charles Richardson, MD<br />

Esmail Elwazir, MD*<br />

Greg Hodges, MD*<br />

Bhavani Moparty, MD**<br />

Chris Vesy, MD<br />

Texas Digestive Health Consultants (Health<br />

Texas/Baylor affiliate) (214) 820-8899<br />

Steve Burdick, MD**<br />

**Star designations: * ERCP **ERCP and EUS<br />

GI lab phone: (214) 820-3463<br />

(214) 820-4627<br />

Liver Consultants of Texas<br />

Inpatient Hepatologists (214) 820-8500<br />

Jacqueline O’Leary, MD<br />

Rita Lepe, MD<br />

Linsheng Guo, MD


James Trotter, MD<br />

Liverresources.com<br />

48<br />

GENERAL GI/LIVER TOPICS<br />

How do I get a GI consult?<br />

In general, you can call whomever you want. There are a<br />

few things to keep in mind- there is no consult schedule or<br />

GI service. Some gastroenterologists predominantly focus<br />

on outpatient Gastroenterology, and some have special<br />

areas of interest. Of course if a patient has a established<br />

relationship with a Gastroenterologist, then you should call<br />

that particular Gastroenterologist. You can usually find this<br />

information on EMR but it can be tricky.<br />

What do I tell the Gastroenterologist?<br />

Basic patient information; GI issue; Does the patient need<br />

to be seen today? Active bleeding? What/where do you<br />

think they are bleeding from? NSAIDs? Prior endoscopy<br />

(when, where whom) Is the patient NPO, Is a procedure<br />

needed?<br />

When do I call for an urgent GI consult?<br />

Active upper GI bleeding, specifically variceal bleeding.<br />

Most lower GI bleeding (diverticular) stops and is only<br />

occasionally brisk and persistent.<br />

How do I get a Hepatology/Liver consult?<br />

There is an inpatient “liver service.” All consults go to the<br />

general number. The inpatient hepatologist is on service<br />

for a week at a time (usually Monday to Monday). All<br />

established hepatology patients (ie, those previously seen<br />

in the Hepatology clinic or who are on the transplant list)<br />

are admitted by the TPC hospitalist group, so in general<br />

hepatology is already seeing these patients.<br />

What do I tell the Hepatologist?<br />

Basic patient information. Newly diagnosed cirrhosis? If<br />

calling for hepatitis — results of viral serologies,<br />

autoimmune studies, suspected medications.<br />

When do I call for an urgent Hepatology consult?<br />

Acute liver failure — in general, defined as new onset of<br />

encephalopathy, jaundice and coagulopathy. Remember,<br />

if they have risk factors for cirrhosis (EtOH, Chronic viral


49<br />

hepatitis, obesity), then they probably don’t have acute<br />

liver failure; they have decompensated cirrhosis.<br />

GENERAL GASTROENTEROLOGY<br />

C. difficile<br />

• Only one test is indicated: C diff toxin in stool<br />

• The test may sometimes take > 24 hours to return, so<br />

consider empiric treatment with oral Flagyl or Vancomycin<br />

• If a patient is really sick, it is best to start directly with<br />

Oral Vancomycin (pill or suspension): 125 mg po QID;<br />

Otherwise, can use oral flagyl. DO NOT use IV<br />

Vancomycin for C. difficile.<br />

• Always consider C. difficile if unexplained leukocytosis<br />

and diarrhea. Diarrhea is not always present, in fact in<br />

severe C. difficile they may get a dilated colon with ileus,<br />

so consider checking a KUB. If colon is dilated then make<br />

sure GI is following and consider surgical consultation<br />

(Colorectal or general)<br />

Cholangitis<br />

If you suspect a patient has cholangitis, then it is best to call a<br />

gastroenterologist who does ERCP. Cholangitis is an indication<br />

for urgent ERCP. Cholangitis should be suspected if a patient<br />

has symptoms of Charcot’s triad:<br />

1. Fever<br />

2. RUQ pain<br />

3. Jaundice<br />

The patient may also have hypotension and altered mental<br />

status which gives them all five of Reynold’s pentad. Patients<br />

can sometimes just present with vague upper abdominal pain<br />

and elevated transaminases. Always check a right upper<br />

quadrant ultrasound.<br />

Colonoscopy Prep<br />

Nulytely 4 liters- 8 oz PO Q 10-15 minutes until gone. We<br />

usually start this at about 5 p.m. on the day before a planned<br />

colonoscopy. NPO except meds after midnight. Write generous<br />

PRN orders for anti-emetics such as Zofran, Phenergan,


50<br />

Reglan. DO NOT prep a patient unless GI says that they were<br />

able to get the patient on the schedule for the next day.<br />

GI Prophylaxis<br />

Generally not indicated unless patient is at high risk of GI<br />

bleeding: high dose steroids, previous peptic ulcer disease,<br />

heavy NSAID use, neurotrauma, etc. GI prophylaxis may put<br />

patients at increased risk for C. difficile infection.<br />

Nutrition<br />

• TPN- there is a standard order sheet/order set. You<br />

should become familiar with this order set and in general<br />

write your own TPN. The dieticians are very good at<br />

writing and are a very valuable resource.<br />

• Tube feeds- enteral nutrition is always preferable to<br />

TPN. There are a variety of formulas available at Baylor<br />

(the Baylor EMR website has a list). Remember, Dobhoff<br />

tubes are more comfortable for patients due to their small<br />

size, but crushed meds don’t go down them very well, so<br />

order your meds as suspensions.<br />

Pancreatic Masses<br />

If a patient has a pancreatic mass, and an FNA is indicated,<br />

than it is best to call a gastroenterologist that does EUS/FNA<br />

Pancreatitis<br />

• Always assess severity — mild, moderate, severe — via<br />

Ranson’s criteria or other criteria, and watch closely for<br />

complications.<br />

• If severe, then ICU treatment is needed.<br />

• Treatment- IVF. If necrosis on CT, consider antibiotics<br />

(controversial). Pancreatic necrosis can only be<br />

determined on a CT with IV contrast (which may be<br />

problematic as many patients with pancreatitis develop<br />

AKI)<br />

• Early tube feeds (gastric or duodenal) are controversial<br />

• Always check a sonogram for stones. Consult surgery if<br />

you suspect biliary pancreatitis because they usually need<br />

a cholecystectomy before they leave the hospital. The


51<br />

timing and necessity of ERCP for biliary pancreatitis is<br />

variable.<br />

PEG tubes<br />

Preferences<br />

> 6 months life expectancy<br />

• Indications: Dysphagia- aspiration or penetration<br />

documented by speech therapy or dysphagiagram<br />

• Prefer for patients to be off anticoagulation and no<br />

coagulopathy. ASA is okay. If they have cirrhosis and<br />

ascites, then no PEG tube.<br />

When they “fall out” or are pulled out (this only happens at<br />

night)- replace with a 15-20 French foley catheter and inflate<br />

the balloon ASAP, but do not use the tube until position is<br />

verified or GI has seen patient.<br />

Upper Gastrointestinal Bleeding (UGIB)<br />

Treatment — Use Baylor GI bleeding order set.<br />

• First priority: Volume resuscitation. Ensure two large<br />

bore peripheral IV’s or central line. Give IVF and blood<br />

products as appropriate to keep HR 100.<br />

• Check hemostasis profile and give FFP and platelets as<br />

needed to correct any coagulopathy. General goal: INR<br />

50<br />

• Discontinue anti-platelet agents and anticoagulants.<br />

• Peptic ulcer disease is a common etiology, so give a<br />

Protonix 80 mg IVP, the 8 mg/hr<br />

• If cirrhosis and variceal bleeding suspected, give<br />

Octreotide 50 mcg IVP, then 50 mcg/hr (Octreotide drip<br />

per protocol). Also start cirrhotics with suspected variceal<br />

bleeding on prophylactic antibiotic coverage (usually start<br />

with 3 rd /4 th generation Cephalosporin (such as Ceftriaxone<br />

or Cefepime) or levaquin 500 mg IV qday, then change to<br />

PO


52<br />

• Vasopressin — pressor of choice if not able to maintain<br />

adequate blood pressure with blood product and fluid<br />

resuscitation.<br />

• NGT aspirate: If red blood then may indicate active GI<br />

bleeding. If coffee ground, than probably UGIB within 1 to<br />

2 days.<br />

**A negative NGT lavage does not rule out an UGIB.<br />

Large post-pyloric bleeds such as duodenal ulcers<br />

commonly have negative aspirates. It is usually okay<br />

to remove the NGT after the aspirate (unless you are<br />

going to use it for medications or something else).<br />

• Consult GI: Important things to tell them are<br />

1. Patient name and location<br />

2. Presentation<br />

3. Co morbidities and medications (including any<br />

NSAIDS)<br />

4. Actively bleeding or not (results of lavage)<br />

5. Significant labs: H&H, PT/INR<br />

6. Resuscitation efforts (how much blood/FFP has<br />

been given)<br />

7. Hemodynamics<br />

8. If a procedure is needed<br />

9. Remember the definition of urgent endoscopy is<br />

an endoscopy within 24 hours.<br />

• Follow serial H&H Q6 hours for 1-2 days, then change to<br />

Q 8-12 hrs<br />

• Make sure to repeat INR 1-2 hours after FFP<br />

• Vitamin K: Most cirrhotics who have significant jaundice<br />

are also Vitamin K deficient so give Vitamin K 10 mg SC<br />

daily x 3 days.<br />

• Keep NPO<br />

GENERAL HEPATOLOGY<br />

Acute liver failure<br />

▪ Basic definition: Jaundice, coagulopathy, and AMS<br />

▪ Very complex, sick ICU patients. Acute liver failure can<br />

progress very rapidly. Best managed on 4 west ICU (aka


53<br />

the liver transplant ICU) where the nurses are very<br />

comfortable taking care of liver patients.<br />

▪ Transplant candidacy vs evaluation.<br />

▪ If intubated in the ICU, propofol is usually your sedative<br />

of choice.<br />

▪ Levophed is in general your pressor of choice.<br />

▪ If Tylenol is on your differential, always give at least one<br />

dose of Acetadote- (acetylcysteine) which can be given<br />

orally or IV until the Tylenol level comes back.<br />

Alcoholic hepatitis<br />

▪ Always calculate the discriminant function and consider<br />

steroids or Trental if >32<br />

▪ No steroids if any sign of infection<br />

▪ Give folate 2 mg daily and thiamine 100 mg daily<br />

▪ Nutrition is very important. Always consider tube feeds<br />

(at least for a couple of days) if the patient does not have<br />

good PO intake.<br />

▪ Withdrawal precautions: Oxazepam preferred over other<br />

benzodiazepines for withdrawal. Librium is very longacting<br />

and can be problematic. Consider non-selective<br />

beta-blockers as well, if the patient is hyperadrenergic<br />

(hypertensive, tachycardic)<br />

▪ Vitamin repletion: Always give thiamine before any<br />

dextrose containing IV fluids. Because of malnourishment,<br />

alcoholics often have thiamine, folate, and magnesium<br />

deficiencies. Suggested orders: Add to first bag of IV<br />

fluids daily (aka the “banana bag”) Thiamine 100 mg,<br />

Folate 2 mg, one vial of multivitamins. Okay to follow Mg<br />

levels or give 1-2 grams of Magnesium sulfate IV daily for<br />

the first day or two. Watch Phosphate levels for refeeding<br />

syndrome.<br />

▪ High mortality<br />

Decompensated Cirrhosis<br />

When managing cirrhotics, mention patients Child’s Class or<br />

MELD score (MELD score if preferable if pt is a transplant<br />

candidate or is on the transplant list). Also mention underlying<br />

cause if known (Laennec's cirrhosis, etc)<br />

Hepatic encephalopathy<br />

Stages of encephalopathy: The simplest assessment system<br />

(most commonly used) grades HE as stages 1 to 4. The<br />

grading is based upon changes in consciousness.


54<br />

Stage 1: Mild confusion, decreased attention,<br />

irritability, reversed sleep pattern<br />

Stage 2: Drowsiness, personality changes,<br />

intermittent disorientation, asterixis<br />

Stage 3: Gross disorientation, marked confusion,<br />

slurred speech<br />

Stage 4: Frank coma<br />

The grading/staging of HE can be difficult. The presence of<br />

asterixis is a fairly reliable indicator of at least stage II HE.<br />

** Always look for what precipitated the HE. Common<br />

etiologies: Infection, bleeding, electrolyte abnormality,<br />

dehydration.<br />

• Kristalose (same as Lactulose but tastes better and<br />

comes as packets of crystals): a good starting does is 20-<br />

30 g po TID, then titrate to 3-4 BM/day<br />

• Rifaxamin: 400 mg PO TID- this is very expensive, and<br />

so it can be difficult to continue as an outpatient<br />

• For your patients with Stage III/IV HE or refractory HE:<br />

Kristalose 30-60 grams every hour until BM. Lactulose<br />

enema: 200 g of lactulose in 800-1000 mL water<br />

Ascites-volume overload<br />

Large volume paracentesis is greater than >2L<br />

If the patient’s serum albumin is less than 3 g/dL, then give 8 to<br />

10 g of albumin per liter of ascites removed. All albumin at<br />

Baylor is “sodium poor” so no need to specify “sodium poor<br />

albumin- SPA”. Albumin comes in 25 g vials, so it is best to<br />

round to the next highest 25 g interval. Usually best to hang<br />

the albumin as you are about to do the tap.<br />

• Diagnostic paracentesis - SBP, etc.<br />

- Send for: cell count/diff, albumin, total protein<br />

- Inoculate culture bottles at bedside with 10 mL of<br />

ascitic fluid in each bottle (increases yield)<br />

- SBP if >250 PMNs<br />

• Coagulopathy is not a contraindication to paracentesis.<br />

In general, we do not give FFP or platelets prior to a<br />

paracentesis unless the patient has a severe<br />

coagulopathy


55<br />

GI bleeding<br />

(**See above under GI Bleeding; in addition, think about the<br />

following)<br />

• All cirrhotics with GI bleeding should get prophylactic<br />

antibiotics to prevent SBP. Good options include a 3rd or<br />

4th generation cephalosporin or quinolone. Antibiotics<br />

should be continued for 5 days.<br />

• Fluid resuscitate- central line preferred. If not, then<br />

ensure a 18-20G IV in each arm<br />

If INR>2, then give at least 4Units FFP<br />

• Give platelets if


Liver transplant<br />

56<br />

Liver transplant evaluation (LTE)<br />

▪ Can only be initiated by a hepatologist.<br />

▪ Standardized 3 page order set which includes an<br />

extensive battery of imaging studies, labs, and consults.<br />

The evaluation usually takes 2-3 days minimum to<br />

complete. The liver transplant coordinator calls the<br />

consults (Psychiatry, etc.) as the transplant service often<br />

has consultants that they prefer to use.<br />

▪ Be careful what you tell families and patients about their<br />

candidacy for transplant. Remember that the decision to<br />

transplant a patient is a committee decision. In general<br />

always defer this to the hepatologist. Patients and families<br />

are sometimes under the impression that they are being<br />

sent to Baylor for a liver transplant. It is important to tell<br />

the patient and family that a liver transplant evaluation is<br />

required first.<br />

▪ Once a patient is transplanted, it is usually okay to sign<br />

off as the transplant surgery team will completely manage<br />

the patient.<br />

General liver patient guidelines<br />

• Avoid benzodiazepines and narcotics as they can<br />

precipitate encephalopathy<br />

• Tramadol is a good choice for pain management: 50 mg<br />

PO q12 hours prn pain<br />

• Insomnia is very prevalent. It is best to use Trazodone<br />

for insomnia. Do not use Ambien, Lunesta, etc. if possible.<br />

• If agitation is a significant problem, then low dose IM<br />

Zyprexa or Haldol is a possible treatment that can be<br />

used.<br />

• Always notify the liver transplant service if a patient that<br />

is on the liver transplant list is hospitalized.<br />

GI STUDIES<br />

Study Orders<br />

• Abdominal US (NPO 6hrs prior)<br />

• Barium Swallow (NPO 1hr prior)<br />

• Upper GI (NPO after MN)<br />

• SBFT (NPO after MN and one glass of water qhr from<br />

noon to 1900)


57<br />

• Barium Enema (clear liquids 1d prior, NPO after MN,<br />

one glass of water qhr from noon to 1900, MgCitrate at<br />

8pm, Dulcolax at 11pm, Dulcolax at 7am)<br />

• HIDA (NPO after MN)<br />

• Other notes:<br />

- CT abdomen/pelvis- always use oral contract<br />

(Gastrografin). Use IV contrast if possible.<br />

- Plain X-rays: KUBs and acute obstructive series are<br />

always best done in radiology rather than as<br />

portables.<br />

Endoscopy Orders<br />

• Colonoscopy, etc: Clear Liquid Diet day before then<br />

NPO except meds (except antiplatelets and iron) after MN<br />

and Nulytely 250cc PO Q10min until all 4L consumed<br />

starting at 1800<br />

• EGD, etc: just NPO except meds for 6hrs prioir or after<br />

MN<br />

• Permits on chart for colonoscopy, endoscopy, and<br />

anesthesia<br />

• To GI lab on call<br />

• If pt is still passing stool in am the give fleet enema x1<br />

• Have functioning IV (not heplock). The best way to do<br />

this is just to order IV fluids to start 4-6 hours before the<br />

procedure.<br />

• Patient to resume diet when alert ~1hr (for capsule can<br />

resume liquid/diet 2/4hrs after swallow<br />

• Benefits: 1/20 r/o cancer vs Risks: 1/500 r/o significant<br />

bleed, 1/2000 r/o perforation


58<br />

INFECTIOUS DISEASES<br />

BUGS AND DRUGS<br />

(This is not a comprehensive list, but think of these drugs when<br />

you are dealing with the listed bugs; refer to Sanford Guide<br />

and your prescribing references for treatment doses and<br />

specific clinical scenarios)<br />

Atypical PNA (Chlamydia, Mycoplasma, Legionella)<br />

• Azithromycin (Zithromax)<br />

• Levofloxacin (Levaquin)<br />

Candidemia<br />

• Micafungin (Mycamine)<br />

• Fluconazole (Diflucan)<br />

• Voriconazole (Vfend)<br />

• Amphotericin B<br />

• Liposomal Amphotericin B (AmBisome)<br />

Candiduria<br />

• C. albicans (No chronic foley, has symptoms, +pyuria):<br />

Fluconazole<br />

• C. glabrata (With symptoms): Fluconazole, Amphotericin<br />

B<br />

Chronic foley: Change out foley and monitor (unless<br />

neutropenic)<br />

Good anaerobic coverage:<br />

• Zosyn (and anti-pseudomonal penicillins)<br />

• Merrem (and other carbepenems)<br />

• Clindamycin (anaerobes above the diaphragm) (Cleocin)<br />

• Metronidazole (anaerobes below the diaphragm)<br />

(Flagyl)<br />

MRSA<br />

• Vancomycin<br />

• Linezolid (Zyvox)<br />

• Trimethoprim/Sulfamethoxazole (Bactrim)<br />

• Daptomycin (Cubicin)-not indicated for tx of PNA<br />

• Tigecycline (Tygacil)<br />

• Minocycline (for CA-MRSA)<br />

• Doxycycline (for CA-MRSA)


59<br />

Pseudomonas:<br />

• Piperacillin/Tazobactam (Zosyn)<br />

• Meropenem (Merrem)<br />

• Imipenem/Cilastatin (Primaxin)<br />

• Doripenem(Doribax)<br />

• Ceftazidime (Fortaz)<br />

• Cefepime (Maxipime)<br />

• Gentamicin (Garamycin)<br />

• Tobramycin (Nebcin)<br />

• Amikacin (Amikin)<br />

• Ciprofloxacin (Cipro)<br />

• Levafloxacin (Levaquin)<br />

• Colistin (for multiresistant strains)<br />

VRE<br />

• Linezolid (Zyvox)<br />

• Daptomycin (Cubicin)<br />

• Tigecycline (Tygacil)<br />

• Quinupristin and dalfopristin (Synercid)<br />

Etiologies<br />

FEVER IN THE ICU<br />

• VAP (PNA developing after 48 hours intubation)<br />

- Risk highest in the first week<br />

- Higher risk in patients with comorbidities, ARDS,<br />

paralyzed, H2B, NGT; mortality 20 to 60 percent.<br />

- Infection control/prevention: NIV; if possible,<br />

carafate over other anti-ulcer, tight cuff seal (>20cm);<br />

semi-recumbent position.<br />

• Central line infection<br />

- Infection rate: Fem>PICC>IJ>SCL<br />

- No evidence to support prophylactic scheduled<br />

changes, but should be changed if new infection<br />

arises. Consider changing anyway if in >3 weeks.<br />

• Other catheter related infections (foley catheter,<br />

arterial line, peripheral IV)<br />

• CMV infection after blood transfusion<br />

• Surgical site infections


60<br />

• Resistant pathogens: MRSA, VRE, Pseudomonas<br />

• Other infections: Cellulitis, cholangitis, cholecystitis,<br />

diverticulitis, endocarditis, intra-abdominal abscess,<br />

meningitis, sinusitis, thrombophlebitis<br />

• Non-infectious causes: Transfusion reactions, drug<br />

fever, intra-abdominal source (pancreatitis, acute<br />

mesenteric ischemia), thyroid disease, or thromboembolic<br />

disease (DVT/PE)<br />

Work-up and treatment — Consider the following:<br />

• CBC with diff, CMP<br />

• Repeat blood cultures x2<br />

• CMV PCR<br />

• UA/urine culture<br />

• Sputum gram stain/culture<br />

• Change out central lines if >48 hours (venous lines first)<br />

and culture tips<br />

• pCXR<br />

• Stool studies if indicated<br />

• Abdominal ultrasound if indicated<br />

• CT chest, abdomen, or pelvis if indicated<br />

• Bilateral lower extremity Doppler if indicated<br />

• CT sinuses if chronic NG tube<br />

• Empiric antibiotics<br />

Definition<br />

FEVER OF UNKNOWN ORIGIN<br />

• Fever >101°F (38.5°C) on one or more occasion<br />

• Duration >3 weeks<br />

• No diagnosis despite 1 week of intensive evaluation<br />

Etiologies<br />

• Infection:<br />

Tuberculosis, endocarditis, intra-abdominal abscess,<br />

osteomyelitis, fungal infection, meningitis, hepatitis, CMV,<br />

EBV, Lyme disease, HIV, etc.<br />

• Connective tissue disease:<br />

Temporal arteritis, Polyarteritis nodosa, RA, SLE, etc.


61<br />

• Neoplasm:<br />

Lymphoma, leukemia, carcinoma, etc.<br />

• Others: Drugs, DVT, PE, adrenal insufficiency, etc.<br />

Work-up — Consider if appropriate:<br />

• Reassess medications<br />

• Thorough history and physical exam<br />

• Lab — CBC with diff, CMP, Blood cultures x2, UA, urine<br />

culture, sputum gram stain and culture, Quantiferon Gold,<br />

ESR/CRP, ANA, RF, LDH, CMV PCR, EBV PCR, HSV<br />

PCR, Lyme titers, Hepatitis panel, HBV or HCV PCR, HIV<br />

antibody or PCR, fungal complement panel, D-dimer<br />

• Imaging — TTE followed by TEE if indicated, CXR, CT<br />

of targeted area, LE Doppler, CT chest with PE protocol,<br />

bone/gallium scan<br />

• Procedures — Lumbar puncture, bone marrow biopsy,<br />

temporal artery biopsy<br />

PNEUMONIA<br />

Use pneumonia admission protocol<br />

SEPSIS<br />

Define the condition of your patient in your notes<br />

using the following:<br />

• SIRS — 2 out of the 4 following criteria:<br />

- T>38 or 90<br />

- RR>20 or PaCO212,000 or >10 percent Bands<br />

• Sepsis — SIRS in response to a documented or<br />

suspected infection (does not have to have proven<br />

infection to call it sepsis)<br />

• Severe sepsis — Sepsis PLUS signs of organ<br />

hypoperfusion or damage, such as:<br />

- Capillary refill >3 sec<br />

- Mottled skin<br />

- Uop 4 mmol/liter


62<br />

- Altered mental status<br />

- Platelets 15<br />

mcg/kg/min or NE/Epi >0.25 mcg/kg/min for MAP>60<br />

Goals in sepsis:<br />

• MAP 65 to 90 (MAP = [SBP+(DBPx2)]/3)<br />

• CVP 10 to 12 (>12 if intubated)<br />

• SvO2>70 (can draw random ScvO2: early goal directed<br />

therapy suggests to transfuse to Hct>30 percent, then<br />

redraw; if 65 or SBP>90 OR<br />

• CVP≥8 or ≥12mmHg if intubated OR<br />

• Total fluid bolus of 45 ml/kg have been given including<br />

all fluid boluses in ER and on floor within 6 hours of<br />

arriving in the ICU.<br />

• If still hypotensive, then initiate pressors.<br />

• Establish central access<br />

Pressors:<br />

• Start with Levophed gtt: titrate to keep MAP>65<br />

• Can then escalate based on specific patient<br />

• Vasopressin can be added at 0.01-0.04 Units/min,<br />

neosynephrine starting at 100-180 mcg/min, or dopamine<br />

starting at 5 mcg/kg/min. Addition of vasopressin to high<br />

doses of levophed have shown to cause increases in


63<br />

mortality. It lowers mortality if added to moderate doses of<br />

levophed.<br />

Antibiotics — First dose stat in ER<br />

Blood cultures — x2 drawn in ER prior to first dose<br />

antibiotics<br />

• Order labs and antibiotics based on suspected etiology<br />

• Consider pharmacy evaluation for Xigris if >2 organ<br />

system failure 2/2 sepsis or APACHE II score ≥25<br />

Other factors in shock — If still refractory hypotenstion,<br />

check Ca, TSH, possible hemorrhage into any organ, GIB,<br />

TTE, acidosis. HCO3 drip if ph


Histoplasmosis<br />

HIV<br />

64<br />

Urine histo antigen, LDH.<br />

HIV (Multidrug-resistant) HIV genotype<br />

Acute retroviral syndrome: Order<br />

HIV PCR for viral load and CD4<br />

count.<br />

Chronic illness or AIDS: HIV<br />

antibody/CD4 count.<br />

Meningitis Blood cultures x2, CT head without<br />

contrast to r/o mass effect before<br />

LP (if indicated), LP: opening<br />

pressure, CSF gram stain and<br />

culture, Cell count with diff,<br />

Glucose, Protein.<br />

Osteomyelitis<br />

Pneumonia (Communityacquired)<br />

Pneumonia<br />

(immunocompromised)<br />

Also consider if indicated: CSF for<br />

acid fast stain/culture, fungal<br />

stain/culture, cryptococcal antigen,<br />

HSV/VZV/Enteroviral/CMV/West<br />

Nile PCR, Lyme IgG/IgM<br />

antibodies, VDRL, cytology, Serum<br />

Toxo IgG/IgM HIV test, RPR, ANA,<br />

RF<br />

Blood cultures x2, surgical<br />

sampling/needle biopsy (not swab<br />

of sinus tract or fistula), MRI (most<br />

Se and Sp)<br />

CXR, blood cultures x2, Sputum<br />

gram stain and culture, Urine<br />

Legionella antigen, Urine Strep<br />

Pneumo antigen, Rapid influenza<br />

nasal swab; consider HIV test<br />

All under CAP plus Blood fungal<br />

culture, Induced sputum for silver<br />

stain (PCP), sputum fungal<br />

stain/culture, sputum for acid fast<br />

bacilli stain/culture (TB),


Pneumonia<br />

(immunocompromised)<br />

(continued)<br />

Prion disease: Creutzfeldt-<br />

Jakob disease<br />

65<br />

Quantiferon Gold (TB), CMV PCR,<br />

HSV PCR, fungal compliment<br />

panel, aspergillus galactogamman<br />

(aspergillus), urine histo antigen;<br />

also consider bronchoscopy with<br />

fungal, bacterial, mycobacterial,<br />

viral cultures, with appropriate viral<br />

PCR’s, silver stain (PCP),<br />

Legionella DFA, Legionella culture,<br />

MTB Direct probe, and nocardia<br />

culture<br />

Send CSF for 14-3-3 Protein; If<br />

concern for prion disease, notify<br />

epidemiology as special<br />

precautions need to be taken.<br />

SBP Send ascitic fluid for: albumin, total<br />

protein, gram stain and culture<br />

(bedside inoculation of culture<br />

bottles increases Se), cell count<br />

with diff; can also send amylase,<br />

triglycerides, AFB stain/culture,<br />

adenosine deaminase (if TB<br />

suspected), or cytology<br />

Tuberculosis AFB sputum stain and culture x3<br />

(order induced sputum if needed);<br />

PPD or Quantiferon Gold


66<br />

NEUROLOGY<br />

ALTERED MENTAL STATUS<br />

Patient states:<br />

• Confused: disoriented but calm<br />

• Delerium:disoriented but agitated<br />

• Lethargic: Drifts off to sleep<br />

• Coma:Unarousable and unresponsive<br />

Etiology: MOVE STUPID<br />

• Metabolic (hypothyroid, hyperthyroid, hepatic<br />

encephalopathy)<br />

• Oxygen (Hypoxia from PNA, pulm edema, etc)<br />

• Vascular (TIA, CVA, Subdural hematoma, TTP)<br />

• Electrolytes (Specifically Na, Ca)<br />

• Seizure<br />

• Trauma<br />

• Uremia<br />

• Porphyria<br />

• Infection (sepsis/meningitis)<br />

• Drugs/Toxins<br />

Immediate ER cocktail (if history unobtainable): Thiamine<br />

IV (always give before glucose), D50, Narcan. Flumazenil only<br />

if BZD OD certain.<br />

Immediate assessment — Intubate if indicated. Vitals,<br />

Exam, ABG, DFS, O2 sat, EKG, utox<br />

Initial labs — CBC, CMP, serum osmolar gap,<br />

Acetaminophen level, Salicylate level, appropriate med levels if<br />

suspected, serum ETOH, TSH, Blood cultures x 2, UA and<br />

urine cx<br />

Consider additional diagnostic studies — CT Head<br />

(non-contrast), CXR, LP, EEG, additional infectious work-up if<br />

indicated


67<br />

BRAIN DEATH EXAM<br />

• Can order brain death exam order set and it guides you<br />

through the following:<br />

• Brain death is a clinical diagnosis<br />

• Need to exclude the presence of<br />

exogenous/endogenous toxins<br />

• Patient can’t be hypothermic: Need to warm them up to<br />

declare them brain dead<br />

• Exam has 3 components (need to have all of the<br />

following): 1) Coma 2) Absent brain stem reflexes 3)<br />

Apnea test<br />

1. Coma: Needs to be at least 6 hours if patient has a<br />

structural lesion and 24 hours if patient has anoxic<br />

brain injury<br />

2. Brain stem reflexes:<br />

- Absent motor response<br />

- Pupils are midposition or dilated (4-9 mm), absent<br />

light reflex, doll’s eye maneuver<br />

- Absent corneal reflex<br />

- Absent oculovestibular reflexes (30-60 cc ice water<br />

in ear canal results in no movement; in normal<br />

person, fast beat is described by COWS: cold<br />

opposite, warm same, in coma, a response would be<br />

seen if eye slowly moves toward ear irrigated with<br />

cold water)<br />

- Absent jaw jerk<br />

- Absent gag reflex<br />

- Absent cough with tracheal suctioning<br />

- Absent sucking or rooting reflex<br />

If all brain stem reflexes are absent, proceed to<br />

3. Apnea test: Pre-oxygenate at 100% FiO2 x 5-10<br />

minutes. Would like pCO2 to be around 40 to begin<br />

with if possible. Then, disconnect from ventilator<br />

support for 8-10 minutes (deliver O2 at 8-10L/min, a<br />

small canula is placed down the ET tube) and watch<br />

for respirations. A positive test is absence of any<br />

respiratory response and a post test ABG with PaCO2<br />

>60 or 20 mmHg greater than baseline.<br />

4. Confirmatory testing (Not mandatory):<br />

- Brain flow study: nuclear scan to evaluate for<br />

cerebral blood flow (no flow when ICP exceeds SBP)bedside<br />

(pitfall – does not evaluate posterior<br />

circulation)


68<br />

- EEG silence x2 12 hours apart (pitfall – can be<br />

confounded with medications on board, also at high<br />

sensitivities, much artifact comes through)<br />

- Cerebral angiography-Gold standard (no flow-no<br />

brain. pitfall – costly, invasive, requires transporting<br />

patient out of ICU setting to radiology, not readily<br />

available)<br />

5. Southwest Organ Transplant can come and talk to the<br />

family about organ donation, but keep that separate<br />

from the talking you do with the family.<br />

NEUROMUSCULAR EMERGENCIES<br />

Some patients will present with generalized weakness with<br />

certain neurological conditions. This may result in bulbar<br />

(facial) or respiratory weakness, and require close monitoring.<br />

Patients with severe bulbar weakness are more likely to<br />

require mechanical ventilation.<br />

• The following conditions in particular should prompt<br />

special attention: Guillain-Barre, Myasthenia Gravis<br />

Exacerbation, Polymyositis<br />

• Watch FVC and Negative Inspiratory Force (NIF)<br />

frequently (approximately Q6 hours). NIF=Maximum<br />

Inspiratory Pressure (MIP). You can write an order in the<br />

chart to monitor NIF as above and this will be performed<br />

by respiratory therapy.<br />

• If FVC drops below 15 cc/kg, the patient will require<br />

intubation and ventilation.<br />

• NIF should be at least -25 cm H20. If NIF begins to<br />

become more positive, this may indicate worsening<br />

diaphragmatic weakness and require intubation.<br />

• Also severe facial/bulbar weakness may make<br />

performance of bedside spirometry difficult if not<br />

impossible. Patients should be able to take a deep breath<br />

and count out loud to at least 1 to 20 in a single breath. If<br />

the time period is shorter, the patient may need to be<br />

intubated.<br />

• Follow ABG and if PaCO2 if creeping up, then have a<br />

low threshold for intubation.


69<br />

SEIZURES<br />

Can use BZD ativan IV or valium rectally if no access (0.1<br />

mg/kg max IV if needed) to stop seizure, most seizures will be<br />

self limiting and brief not requiring treatment. If patient having<br />

frequent convulsive seizures and not returning to baseline<br />

between events or if two or more events last longer than 30<br />

minutes and patient not awakening between, see status<br />

epilepticus below.<br />

Etiology: ABCDE<br />

• Alcohol withdrawal, illicit drugs<br />

• Brain tumor or trauma<br />

• CVA<br />

• Degenerative disorders of the CNS (Alzheimers)<br />

• Electrolytes (Na) and other metabolic (uremia, liver<br />

failure, hypoglycemic), Epilepsy<br />

Diagnostic studies — CBC, CMP, Utox, med levels,<br />

ETOH level, EEG, MRI or CT head, LP<br />

Treatment:<br />

1. Treat underlying condition<br />

2. Anti-epileptic drugs (AED) for patients with underlying<br />

structural disorder or idiopathic seizure plus: a) status<br />

on presentation, b) focal neuro exam, c) Todd’s<br />

paralysis, or d) abnormal EEG<br />

3. Introduce slowly and monitor closely<br />

4. Check levels on medication until therapeutic<br />

5. May consider withdrawing tx if seizure free for a<br />

defined interval (ex: 1 year) and normal EEG in select<br />

patients<br />

6. In TX: Need to be seizure free x 6 months to drive<br />

STATUS EPILEPTICUS<br />

Definition — One continuous seizure lasting >5-10min or<br />

two or more discrete seizures between which there is<br />

incomplete recovery back to baseline<br />

Stat labs — DFS, Na, Ca, serum and urine tox screen, AED<br />

levels


70<br />

Additional studies — MRI brain with and without contrast<br />

with seizure protocol, need LP<br />

Treatment:<br />

1. Intubate if indicated<br />

2. Ativan 0.1mg/kg IV at 2mg/min; if no response, then<br />

3. Dilantin 20mg/kg IV at 50 mg/min (or Cerebyx 20mg<br />

p.e./kgIV at 150mg p.e./min); if no response, then<br />

4. Additional IV dilantin or cerebyx (5-10mg/kg) bolus; if<br />

still no response, and continued sz>one hr, or<br />

hyperthermic, then definitely needs intubation if not<br />

already done, EEG monitoring, and ICU admission;<br />

then,<br />

5. Phenobarbital 20mg/kg IV at 50-75 mg/min initially,<br />

then additional 5-10 mg/kg bolus if still seizing; if no<br />

response then<br />

6. Sedate (versed 0.1mg/kg, then run at 10mcg/kg/min<br />

or propofol 2mg/kg, then run at 5mg/kg/hr)<br />

7. Additional phenobarb prn<br />

8. Pentobarb coma as last line of treatment with<br />

continuous EEG monitoring in place. Titrate<br />

pentobarb to burst suppression with 1 to 3 bursts per<br />

minute.<br />

Neuro consult, EEG monitoring (if sedated/unclear status)<br />

CVA: Hemorrhagic<br />

STROKE MANAGEMENT<br />

• Intracranial or SAH<br />

• Usually intubated either 2/2 AMS, elective<br />

hyperventilation, or post-craniotomy/repair/ventric<br />

placement.<br />

Diagnostic studies — Labs including CBC, CMP, PT/INR<br />

and urine drug screen, non-contrast CT head, LP to check for<br />

xanthochromia if no evidence of SAH on CT, but suspicion still<br />

high<br />

Treatment:<br />

1. Stat neurosurgery consult to review films/patient<br />

2. Admit using Hemorrhagic stroke protocol


71<br />

3. Stop anticoagulants and reverse coagulopathies,<br />

vitamin K, FFP<br />

4. Insulin for hyperglycemia<br />

5. Usually hypertensive: treat to MAP 100-120; maintain<br />

CPP (MAP-ICP) >60-70.<br />

6. HTN is usually labile use gtt: nicardipine, nipride or<br />

labetalol based on other comorbidities.<br />

7. Load with Dilantin or cerebyx to levels of<br />

approximately 20. Most indicated in lobar ICH, SAH,<br />

or subcortical ICH with diameter >4cm and shift.<br />

8. Treat ICP (goal < 20): elevate HOB to 30 degrees,<br />

sedate using propofol, mannitol IV at 1 g/kg bolus<br />

followed by 0.5 to 0.25g/kg q6hours(follow Na, Posmkeep<br />

300 to 320), hyperventilate (goal pC02 25-30)<br />

9. Bilateral SCD’s for DVT prophylaxis<br />

CVA: Ischemic<br />

• Admit using ischemic stroke protocol<br />

• If indicated, admit to stroke unit (3 Truett)<br />

Labs — CBC, CMP, Fasting Lipid level, DFS, HgbA1C, PT,<br />

PTT, utox, hypercoagulable work-up and blood cultures on<br />

young patients<br />

Imaging — Stat CT head without contrast to evaluate for<br />

hemorrhage, MRI/MRA head and neck or CTA head and neck,<br />

Carotid Doppler if you do not obtain other imaging of the<br />

neck(carotids), EKG, TEE in patients who are suspected to<br />

have embolic stroke without known source (Afib), TTE with<br />

Bubble study is acceptable as screen in others if low suspicion<br />

of central embolic process (cross out TEE on protocol as you<br />

want to order TTE with bubble study instead)<br />

Treatment:<br />

1. If


72<br />

4. Tx of HTN not of proven benefit unless >220/120 or<br />

comorbidities present: aortic dissection, MI, CHF, IC<br />

mass, etc.<br />

5. If giving lytics, treat if sbp>185, dbp>110.<br />

6. Statin: Consider Zocor 40 mg HS.<br />

7. DVT prophylaxis: Lovenox 40 mg SC daily vs heparin<br />

sc BID/TID, with renal insufficiency/failure, lovenox 30<br />

mg sc daily<br />

8. If cerebral edema (peaks 3-4 days post-stroke) with<br />

shift/impending herniation, then treat as elevated ICP<br />

(below).<br />

9. Carotid endarterectomy if indicated (see NASCET<br />

and ACST trials)


73<br />

ONCOLOGY<br />

THE ACUTE LEUKEMIC<br />

“The greatest ‘crumpability’ of any hospital patient you will care<br />

for.”<br />

-Troy Neal M.D.<br />

The acute leukemic patient, AKA the acute leuk, is a common<br />

admission during a typical ward month at <strong>BUMC</strong>. As house<br />

staff, we are involved generally in the care of patients with a<br />

NEW diagnosis.<br />

Nuts and bolts — Acute leukemia results from the clonal<br />

expansion of a hematopoietic precursor that has lost the ability<br />

to differentiate while maintaining the ability to proliferate. AML<br />

represents >80 percent of adult cases with a median age of 65<br />

years. ALL represents


74<br />

7. Serum and urine lysozyme (may be useful in cases with<br />

monocytic features)<br />

8. HLA Class I & II DNA-SBT— if patient candidate for<br />

allogeneic HSCT<br />

9. HSV IgM/IgG serologies<br />

10. Coagulation studies to rule out DIC including PT, PTT,<br />

fibrinogen, and D-dimer<br />

11. Lumbar puncture to assess cytology and administer<br />

chemotherapy for all ALL patients (sanctuary sites) and for<br />

AML patients with symptoms of CNS dysfunction<br />

Make sure your patient has the following:<br />

1. Central access via TLC (subclavian preferable for<br />

patient comfort but a non-compressible site) or PICC line<br />

by IV services (may refuse if platelets below their<br />

threshold-usually 50K, but can transfuse platelets in<br />

preparation of PICC)<br />

2. Preserved left ventricular systolic function as confirmed<br />

by TTE or MUGA scan before use of anthracyclines.<br />

3. Aggressive bicarbonate-containing IVFs to alkalinize the<br />

urine and prevent uric acid nephropathy from tumor lysis<br />

(Generally D5W in 1/2NS with 2 amps HCO3 @ 150<br />

cc/hour)<br />

4. Allopurinol 300 mg PO BID +/- rasburicase also for TLS<br />

prophylaxis<br />

5. Prophylactic antimicrobials, typically in the form of<br />

Levaquin 500 mg PO daily, Posaconazole 200 mg PO<br />

TID, and Famvir 250 mg PO BID (If HSV IgG/IgM+) once<br />

ANC approximately 500-1000<br />

6. Orders for daily weights and strict I/O’s (many chemo<br />

regimens have a large volume and need to watch for signs<br />

of volume overload)<br />

7. Orders for daily CMP and CBC<br />

8. Orders for daily TLS labs initially including potassium,<br />

uric acid, LDH, phosphorous, and calcium


Timeline*:<br />

75<br />

Day 0 (admit) — Bone marrow biopsy and other<br />

evaluations<br />

Day 1 — Induction chemotherapy with “7+3” (cytarabine &<br />

idarubicin/daunorubicin) written by Heme-Onc attending<br />

Day 10 to 14 — Bone marrow biopsy #2 to evaluate for<br />

aplasia; G-CSF if no blasts to recover neutrophils<br />

Day 30 (as outpatient) — CBC and Bone marrow biopsy<br />

#3 to assess for complete remission (CR); CR = clean<br />

bone marrow in the setting of no peripheral cytopenias;<br />

CR does NOT equal cure, therefore, induction<br />

chemotherapy if successful, must always be followed by<br />

consolidation therapy (occurs at later admission)<br />

*The above timeline roughly represents a routine<br />

admission for an acute leukemic patient. Obviously, there<br />

will be variation and numerous exceptions depending<br />

upon whether or not remission was achieved, tolerance of<br />

chemotherapy, infectious issues, etc. Intended for<br />

simplified overview only. Day to day supportive care<br />

issues omitted.<br />

Fever in the acute leukemic:<br />

In general, you want to be sure to do the following:<br />

• Examine the patient<br />

• Blood cultures x2<br />

• Fungal culture<br />

• UA and Urine culture<br />

• Sputum culture if cough<br />

• CXR<br />

• Advance antibiotics: typically with first fever, we advance<br />

from levaquin to vancomycin and merrem. The second<br />

time the patient fevers, we advance from posaconazole to<br />

voriconazole. If they continue to fever, you can consider<br />

adding micafungin but will likely need ID involvement.<br />

Most attendings have a preference that they will specify<br />

for antibiotic advancement. Also, if there is a defined<br />

etiology, obviously treat appropriately with antibiotics.


76<br />

Shortness of breath in the acute leukemic:<br />

Worry about typical causes of shortness of breath in addition to<br />

severe anemia and opportunistic infections. Also, consider<br />

leukostasis leading to hypoxemia if blast counts are greater<br />

than 50,000 to 100,000. If the patient just started<br />

chemotherapy, they could be having an acute inflammatory<br />

reaction secondary to treatment or they could have pulmonary<br />

edema secondary to volume overload. In these instances,<br />

consider the following possible treatments based on suspected<br />

etiology and diagnostic work-up: advance airway/oxygen<br />

support as needed, transfer to the ICU if needed, appropriate<br />

antibiotics, leukapheresis, and/or IV Lasix.


77<br />

PALLIATIVE CARE AND CLINICAL<br />

ETHICS<br />

The Palliative Care Consultation Service (PCCS) and the<br />

Clinical Ethics Committee are a vital element of patient care at<br />

<strong>BUMC</strong>. The services are closely linked, but not identical.<br />

The Clinical Ethics Committee is a multidisciplinary committee<br />

of the medical staff responsible for developing and maintaining<br />

clinical ethics policies/guidelines, ethics education, and clinical<br />

ethics consultation. Baylor house staff typically interact with the<br />

ethics committee when an ethics consult is requested. Ethics<br />

consultation may be requested for moral guidance in<br />

circumstances of ethical uncertainty. A consult may be as brief<br />

as a several minute conversation with one of the ethics<br />

committee consultants or may involve the consultant seeing<br />

the patient, reviewing the chart, and actively engaging the<br />

treatment team, patient, and or family to bring resolution to<br />

ethical dilemmas. Ethics consultants are advisers only and do<br />

not write orders nor tell any party what they must do (unless it<br />

is a matter of hospital policy). Any member of a treatment team<br />

may request a consult, though it is customary to seek<br />

involvement from the attending physician prior to this as a<br />

courtesy. An ethics consult may be obtained by contacting the<br />

Medical Staff Office (2-2139) or by calling the office of Dr. Fine<br />

and Dr. Casanova (214-828-5090).<br />

The Palliative Care Consultation Service is a multidisciplinary<br />

team composed of staff physicians, nurses, pharmacists,<br />

speech therapists, nutritionists, social workers, physical and<br />

occupational therapists, and chaplains, all with extra skills and<br />

competencies to help manage patients with advanced lifelimiting<br />

illnesses. It is important to realize that palliative care,<br />

although often serving as a bridge to hospice, is not the same<br />

as hospice. Patients seen by the PCCS may continue to<br />

receive all treatments while receiving expert symptom<br />

management and the additional psycho-social-spiritual support<br />

often needed by patients and families facing the most serious<br />

illness. Unlike clinical ethics consults, members of the palliative<br />

care team help actively manage patients and write orders. The<br />

physicians, nurses, and pharmacist team members all have<br />

special expertise in pain and other symptom management.<br />

Circumstances in which to consider asking for a palliative care


78<br />

consult include assistance with controlling a patient’s symptom<br />

burden, guidance with the often difficult planning and<br />

conversations associated with decisions near the end of life,<br />

spiritual support for patients and their families, and<br />

complimentary therapies. Consults for the Palliative Care<br />

Consult Service (PCCS) are easily obtained by calling 214-<br />

820-PCCS (7227). Routine consults are handled 7 days a<br />

week primarily between 8:30 and 4:30. True palliative care<br />

emergencies may be called in after hours but must be called in<br />

directly by the physician requesting emergency assistance.<br />

Physician team members<br />

• Dr. Robert Fine<br />

• Dr. Mark Casanova<br />

• Dr. Shawnta Pittman-Hobbs<br />

• Dr. Roberto De La Cruz<br />

• Dr. Susan Kohl<br />

Palliative Care nurses<br />

• Min Patel — weekdays (available at 214-497-2612)<br />

• Grace Youseff — weekends (available at 214-724-<br />

5623)<br />

Palliative Care Pharmacist<br />

Jennifer Craft — weekdays<br />

Pain control tidbits<br />

• There is ample evidence that pain is under treated in<br />

American hospitals. Among the barriers to effective pain<br />

management are failure to adequately assess the pain<br />

and failures to prescribe opioids and other pain<br />

medications appropriately.<br />

• Basic pain assessment should always include a pain<br />

severity score. Remember that pain is subjective and a<br />

patient’s pain is what they say it is. Baylor uses a 0 – 10<br />

scale where 0 is no pain at all and 10 is the worst pain<br />

ever or the worst imaginable to the patient. Some patients<br />

may not be able to put a number on their pain. If not, they<br />

should be encouraged to rate the pain as mild, moderate,<br />

or severe.<br />

• Acute and/or intermittent pain requires rapid onset short<br />

acting opioids. The onset of action for these drugs is 5-10<br />

minutes when given IV and 30- 60 minutes when given<br />

orally. Typical duration of action is 3 to 4 hours. Some<br />

commonly used short acting oral opioids include<br />

hydrocodone, immediate release morphine, immediate


79<br />

release oxycodone, and hydromorphone. Commonly used<br />

parenteral opioids are morphine and hydromorphone.<br />

• Chronic or persistent pain requires long acting<br />

(inevitably slower onset) opioids such as sustained<br />

release morphine or sustained release oxycodone – both<br />

typically dosed at 8 to 12 hour intervals, or Transdermal<br />

fentanyl.<br />

• CALCULATION OF ORAL OR PARENTERAL<br />

MORPHINE EQUIVALENTS — This is the standard way<br />

to assess a patient’s opioid analgesic requirements,<br />

generally over a 24 hr period; this allows for summation<br />

and/or rotation to a simpler and more effective regimen of<br />

pain control; the John Hopkin’s opioid calculator is a good<br />

tool for this task.<br />

• When a patient is thought to be refractory to a particular<br />

opioid, consider opioid rotation. When rotating patients<br />

from one opioid to another, begin with 50-75% of the<br />

equianalgesic dose as the maintenance dose and provide<br />

the rest as breakthrough. Then adjust the maintenance<br />

dose as needed to achieve adequate pain relief based on<br />

the breakthrough usage documented. Allow for 10-15% of<br />

the total daily dose as a PRN given every 2-4 hours.<br />

• The preferred route of administration for opioids is oral.<br />

• “The hand that writes the opioids should also write the<br />

bowel regimen.”<br />

• Some useful opiod conversions (see front of chart for full<br />

equianalgesic dosing chart):<br />

- PO Morphine : IV Morphine = 3 : 1<br />

- IV Morphine : IV Hydromorphone = 10 : 2<br />

- PO Morphine : PO Hydromorphone = 30 : 7.5<br />

- PO Morphine : PO Hydrocodone = 1 : 1<br />

• When a patient is in a pain crisis, you may redose if pain<br />

uncontrolled at the opiod’s peak.<br />

• Do not exceed 12 tabs of Norco (325 mg Tylenol) or 8<br />

tabs of Lortab (500 mg Tylenol) in a 24 hr period due to<br />

the risk of acetaminophen toxicity. For this reason, avoid<br />

Percocet and Tylox (oxycodone plus Tylenol) for<br />

chronic/severe pain.<br />

• Dose Fentanyl transdermal patch (Duragesic) based on<br />

50% of the total oral morphine equivalent dose over 24 hr<br />

period. Rapid metabolizers of Fentanyl may require<br />

changing the patch every 48 hrs vs. every 72 hrs. Also,<br />

febrile patients will liberate the medication faster. Patch<br />

may be less effective in thin/cachectic patients due to<br />

unpredictable absorption. Patch reaches peak effect in


80<br />

17-20 hrs and takes the same to be eliminated once<br />

removed. Titrate doses every 48 hrs but no sooner.<br />

• Methadone is often an effective opioid when other<br />

opioids are not working. However, it is easily mis-dosed<br />

and carries some increased risks. Involve a physician,<br />

nurse, or pharmacist member of the palliative care team<br />

when starting and titrating methadone.<br />

• There is no “ceiling” for the amount of opioids that a<br />

patient can have, but side effects may eventually become<br />

limiting and alternatives (like Ketamine, for opiod-sparing<br />

effect) may have to be explored. Undesirable effects to<br />

monitor for are 1.) respiratory depression 2.) over-sedation<br />

3.) delirium 4.) hyperalgesia 5.) myoclonus<br />

• Stimulants such as Ritalin (10 mg upon arising then 10<br />

mg 4-6 hrs later), Dexedrene, and Provigil can offer<br />

periods of improved alertness by combating the sedation<br />

of opioids during the day or more specifically for planned<br />

family time or visits. Avoid doses late in the day to avoid<br />

insomnia.<br />

• For dyspnea/air hunger, consider morphine 1-2 mg IV<br />

every 1-2 hours PRN in an opioid naieve patient. Patients<br />

tolerant of opioids may need higher doses for air hunger<br />

managment.<br />

• Saturate the opioid receptors to achieve sedation before<br />

adding benzodiazepines because you want patients to be<br />

comfortable, not just look comfortable. Benzodiazepines<br />

can mask pain despite a patient’s appearance.<br />

• Always be open to adjuvant therapies such as TENs<br />

unit, heat, trigger point maneuvers (injections, ball in<br />

sock), myorelaxants, neuropathic agents (TCAs,<br />

Neurontin, Lyrica), relaxation/complimentary therapy,<br />

nerve blockade, NSAIDs, palliative radiation,<br />

bisphosphonates, glucocorticoids, anti-emetics, and<br />

scopolamine for control of secretions<br />

• Don’t forget other potentiators of pain such as<br />

emotional, spiritual, or relational distress.<br />

Useful resources<br />

• Hopkins opioid calculator for PDA or on the web at<br />

http://www.hopweb.org/hop/login.cfm; you then create a<br />

user name and password for free to gain access.<br />

• Palliative Care “Fast Facts” available at<br />

http://www.eperc.mcw.edu/ff_index.htm<br />

• CPR Outcomes and Counseling Guidelines tri-fold<br />

brochure


81<br />

• Institutional Ethics and Palliative Care link on the Baylor<br />

home page<br />

Hospice/comfort care measures<br />

Helpful medications/orders if you are transitioning to in-patient<br />

hospice and comfort care:<br />

• The hospice nurse will write orders as she evaluates the<br />

needs of the patient and call you to make<br />

recommendations and get your verbal approval if the<br />

patient is going on in-patient hospice.<br />

• Excess Secretions: Scopolamine patch behind ear<br />

once every 72 hours; if still struggling, can add atropine<br />

1% ophthalmic solution, 2 gtts under tongue Q3 hours prn<br />

• Fever: Tylenol 650 mg PO or per rectum Q4-6 hours prn<br />

pain/fever<br />

• Nausea/Vomiting: Phenergan 12.5 to 25 mg PO or per<br />

rectum Q6 hours prn nausea or vomiting<br />

• Pain regimens: Consult above; can try morphine gtt,<br />

titrate to comfort if patient is nearing end of life and pain<br />

not able to be controlled with orals or patch.<br />

• Air hunger: Morphine 1-2 mg per hour prn; add Oxygen<br />

by NC at 4-6 L, but write for nurse to not check O2 sats as<br />

this is for comfort only.<br />

• Constipation: Milk of magnesia, Miralax, Senna, or<br />

Dulcolax on a daily basis. Constipation is better prevented<br />

than treated. Do not use fiber supplements to treat<br />

constipation due to opioids or at the end of life.<br />

• Wheezing: A/A nebs q4 hours prn.<br />

• If patient aspirates and is under aspiration precautions,<br />

including ordered to be NPO status, consider changing<br />

this to comfort feedings.<br />

• Other symptomatic treatment as needed. Pastoral<br />

services are always available.


NeoSynephrine(phenylephrine)<br />

10-300<br />

mcg/min<br />

Dobutamine<br />

2-20<br />

mcg/kg/<br />

min<br />

Levophed<br />

(norepine<br />

-phrine)<br />

1-40<br />

mcg/min<br />

Dopamine <br />

Epinephrine<br />

2-20<br />

mcg/min<br />

Primacor<br />

(milrinone) <br />

Vasopressin(antidiuretic<br />

hormone)<br />

0.04<br />

units/hr<br />

82<br />

PRESSOR CHART<br />

Alpha Beta Dopa<br />

(renal<br />

recept<br />

or)<br />

Heart<br />

Rate<br />

SVR<br />

Cardiac<br />

output<br />

++ 0 0 0 ↑↑↑ 0<br />

0 +++ 0 ↑↑ ↓ ↑↑<br />

+++ + 0 ↑↑ ↑↑↑ ↑<br />

>10<br />

mcg/<br />

kg/min<br />

2-10<br />

mcg/<br />

kg/min<br />

0.5-2<br />

mcg/<br />

kg/min<br />

↑↑ ↑↑ ↑<br />

+ +++ 0 ↑↑ ↑ ↑<br />

0 ++ 0 ↑↑ ↓ ↑↑<br />

Primarily used in conjunction with levophed or<br />

neosynephrine in septic patients to aid with<br />

peripheral vasoconstriction (direct stimulation of<br />

smooth muscle V1 receptors).


83<br />

PULMONARY<br />

ARDS<br />

Definition: Need all 4 criteria<br />

1. Acute onset<br />

2. PCWP


84<br />

Higher PEEP/lower FiO2<br />

FiO 2 0.3 0.3 0.3 0.3 0.3 0.4 0.4 0.5<br />

PEEP 5 8 10 12 14 14 16 16<br />

FiO<br />

2<br />

0.5 0.5-<br />

0.8<br />

0.8 0.9 1.0 1.0<br />

PEEP 18 20 22 22 22 24<br />

ASTHMA/COPD<br />

Treatment of Asthma exacerbation:<br />

1. Albuterol nebs at least 3 times in first hour, then<br />

scheduled Q2-4 hours, plus prn nebs<br />

2. Steroids: Either IV or PO based on severity (IV not<br />

superior to PO). 60 mg prednisone PO qday or 1<br />

mg/kg prednisone equivalent Q6-12 hours (at Baylor<br />

for severe asthma exac, typically 60 mg IV solumedrol<br />

Q6 hours) until PEFR reaches 70% predicted; then<br />

begin taper.<br />

3. Continue home dose of inhaled steroid if on one<br />

4. O2 per protocol to keep SaO2 above 90%; use NPPV<br />

if patient’s paCO2 begins to normalize or rise; also in<br />

status asthmaticus<br />

5. Determine severity of exacerbation and ward level<br />

versus ICU level of care<br />

6. Check CXR and signs of infection<br />

Treatment of COPD exacerbation:<br />

1. Ipratropium/Albuterol nebs Q1-2 hours to begin<br />

2. O2 per protocol to keep SaO2 >90%<br />

3. Steroids: IV solumedrol at 60 -125 mg IV Q6<br />

hours (usually 60), or oral at 60 mg prednisone PO<br />

Qday<br />

4. Antibiotics: amoxicillin, Bactrim, doxy,<br />

clarithromycin, levoquin (no single abx proven<br />

superior but we typically use levaquin)<br />

5. NPPV: Initiate early if mod/severe dyspnea,<br />

decreased pH/high pCO2, RR>25<br />

6. CXR<br />

7. Smoking cessation counseling


85<br />

MECHANICAL VENITALTION<br />

Oxygen support<br />

Nasal Cannula (NC)<br />

• Each L adds about 3% FiO2 therefore 1L is 24% FiO2<br />

w/ max of 6L and thus Max FiO2 of about 40%<br />

Venturi Mask (VM): Can set an FiO2<br />

• Max FiO2 of 50%<br />

Partial ReBreather (PRB) Mask w/ Reservoir Bag (exhaled<br />

gas mixes with bag oxygen)<br />

• Max FiO2 of 75%<br />

Non-ReBreather (NRB) Mask w/ Reservoir Bag (exhaled gas<br />

does not mix with bag oxygen)<br />

• Max FiO2 of 100%<br />

Types of ventilatory support<br />

Noninvasive Positive Pressure Ventilation (NPPV)<br />

Face/Nasal Mask Continuous Positive Airway Pressure<br />

(CPAP): One continuous pressure during inspiration and<br />

expiration<br />

Uses: Patients whose primary problem is hypoxemia;<br />

typically used with CHF patients as well as OSA<br />

Face/Nasal Mask Bilevel Positive Airway Pressure (BiPAP):<br />

Set different inspiratory/expiratory pressures<br />

Uses: Patients whose primary problem is hypoventilation<br />

or hypoxemia such as COPD, immunocompromised, postextubation<br />

especially if patient is high risk, DNI patients,<br />

PNA, etc.<br />

Inspiratory Pressure (IP): Start at 8 to 10 cm of H2O and<br />

increase as tolerated to improve Tidal Volume (TV) and<br />

decrease work of breathing, which will result in decreased<br />

pCO2.<br />

Expiratory Pressure (EP) ~ PEEP start at 4 to 5 cm of H2O and<br />

increase as tolerated to increase PO2.


86<br />

Invasive Mechanical Ventilation (MV) Modes<br />

Pressure Support Ventilation (PSV): *NOTE: This mode is<br />

only for patients with an intact respiratory drive*<br />

• Patient initiates a breath, which is supported by vent at a<br />

preset pressure<br />

• Flow cycled NOT volume cycled like in SIMV/AC<br />

• “Pressure Support” = inspiratory pressure selected to<br />

achieve adequate TV and ventilatory support<br />

• Can be combined w/ SIMV to partially assist<br />

spontaneous breaths<br />

• Could be considered to make patient more “comfortable”<br />

on vent; also used for SBT at the appropriate level.<br />

Synchronized Intermittent Mechanical Ventilation (SIMV):<br />

• Patient receives vent support at a given tidal volume and<br />

respiratory rate. If patient initiates additional breaths, the<br />

vent provides no support to these breaths unless pressure<br />

support is added.<br />

• This mode has been proposed to prevent respiratory<br />

alkalosis; however, it requires more respiratory muscle<br />

work than AC.<br />

• Used primarily in SICU<br />

Assist-Controlled Mechanical Ventilation (AC): Can set volume<br />

targeted or pressure targeted.<br />

• When using volume targeted: Patient receives vent<br />

support at a given tidal volume and respiratory rate. If<br />

patient initiates additional breaths, the vent delivers the<br />

pre-set tidal volume with each additional breath.<br />

• If the patient is tachypnic, then hyperventilation can<br />

occur<br />

Other modes to minimize lung injury:<br />

• High Frequency Jet Ventilation/Oscillation: Alveoli are<br />

kept fully open as if the patient is kept at full inspiration<br />

while gases are exchanged by oscillating the air at high<br />

frequency<br />

Indications for intubation<br />

• Refractory hypoxemia<br />

• Hypercapnea with respiratory acidosis (note that<br />

patients w/ COPD often live w/ pCO2 b/t 50-70)


87<br />

• Ineffective respiratory effort, ie, Agonal Breathing or<br />

Respiratory Muscle Weakness (Max Inspiratory Force 1d)<br />

I:E Ratio = 1:2 to 1:4 which is determined by your Inspiratory<br />

Flow Rate. TV and respiratory rate in Volume Controlled<br />

Ventilation<br />

Positive End Expiratory Pressure (PEEP) = 0-10 cm of H20<br />

(may have to increase more if clinically indicated)<br />

• Higher levels of PEEP in asthmatics and COPD patients<br />

may worsen auto-peeping<br />

• In ARDS, may have to use higher level of PEEP for any<br />

given FiO2 (see ARDS)


88<br />

Any time a patient is on MV, the minute volume, plateau,<br />

and peak pressures should be monitored and reported it<br />

in your daily note.<br />

VT (VTE) x RR (fTOT) = minute volume (VETOT) L/min<br />

Specific disease states and mechanical ventilation<br />

suggestions:<br />

• Acute Brain Injury: Volume cycled, Avoid PEEP, Limit<br />

suctioning, Hyperventilate with pCO2 of 34-37<br />

• Neuromuscular disease: Volume cycled, Larger VT<br />

(12-15 ml/kg), Higher flow rate<br />

• COPD: Volume cycled, VT (5-7 ml/kg), higher peak flow<br />

rate, lower mandatory rate, low level PEEP(3), Limit<br />

plateau airway pressures, Reduce autopeep/hyperinflation<br />

• ARDS: Volume cycled, VT (4-6 ml/kg), plateau airway<br />

pressures 5 days as the drug<br />

accumulates in adipose tissue.


89<br />

- Daily sedation vacations at 0700 (“Sedation<br />

Vacation”) if the following is NOT present<br />

• FiO2 >60%<br />

• PEEP >10cm<br />

• Neurosurgical Pt<br />

• Increased ICP<br />

• Hemodynamically Unstable<br />

• Neuromuscular Blockade<br />

Consider a pulmonary critical care consult for every<br />

patient on a ventilator. After 48 hours of MV, it is hospital<br />

policy that you must get a pulmonary critical care consult.<br />

Simplistic approach to adjusting the vent<br />

• Low pO2: increase FiO2 or increase PEEP (to recruit<br />

more alveoli)<br />

• High pCO2: increase TV or increase rate (to increase<br />

minute volume)<br />

• Use ratios: pCO2 current x RR current=pCO2 desired x<br />

RR desired<br />

• For every 10 change in pCO2, the pH changes<br />

approximately 0.8 (acutely)<br />

Troubleshooting the vent<br />

Decreased Peak Inspiratory Pressure (PIP)<br />

• Disconnect problem: Consider disconnected tubing, lost<br />

airway<br />

Increased Peak Inspiratory Pressure (PIP)<br />

• First, check plateau pressure<br />

• Do this by pressing Inspiratory Pause Button<br />

• Check PPlat<br />

- Normal (Plateau Pressure10): This means there is increased airway<br />

resistance. Examples of what could be causing this<br />

include: Patient biting tube (increase sedation or add<br />

bite block), Airway Obstruction from bronchospasm<br />

(BD), secretions/aspiration (suction), plugging<br />

(mucolytics), etc. When the alarm goes off, increase<br />

parameter for peak pressure alarm while<br />

troubleshooting the vent: otherwise ventilator stops<br />

giving a breath with each breath when peak pressures<br />

are high and patient is not ventilated.


90<br />

- Increased (Plateau Pressure>30 and gradient of<br />

Peak to plateau


91<br />

• After 1 wk of intubation determine likelihood of<br />

extubation at 2wks. If unlikely proceed with<br />

bedside/surgical tracheostomy with a GS<br />

• Tracheostomy may be beneficial because it is more<br />

comfortable, more ease in clearing secretions, decreased<br />

airway resistance, decreased laryngeal injury, can eat<br />

orally, can partially vocalize, etc.<br />

- Complications: Infection (mediastinitis), bleeding,<br />

accidental removal with closure of stoma and then<br />

blind reinsertion potentially creating a false tract,<br />

injury to surrounding structures<br />

- Consider a Passy-Muir valve when a patient has a<br />

trach after weaning off ventilator to help with talking.<br />

The Passy-Muir valve acts as a one-way valve<br />

allowing air to go in through the trach and be exhaled<br />

through the native airway.<br />

- You can put a red cap over trach and see if pt can<br />

breath/talk fine, and, if so, you can decanulate the<br />

patient (the hole closes on its own in 2-3d)<br />

Oxygen Toxicity — Remember oxygen toxicity (FiO2 >60%<br />

for >48hrs) from the production of oxidizing radicals which<br />

damage membranes, denature proteins, and break DNA<br />

Cardiac Output Changes — Can reduce cardiac output<br />

because of decreased venous return and increase right<br />

ventricle afterload<br />

Respiratory Muscle Atrophy<br />

Trauma to Airway, Dentition, etc<br />

ETT Migration (normally the tip of the ETT should be 2cm<br />

above carina)<br />

Critical Illness Polyneuropathy/Myopaythy<br />

• Consider when patients continually need MV despite<br />

resolution of primary problem<br />

After Extubation<br />

• Sore throat, Hoarseness, Cough, etc: Can be normal<br />

and should resolve.<br />

• Laryngeal Edema<br />

- Usually occurs when patient is extubated from 2-<br />

7days post-extubation. After extubation, an average<br />

of 40% of patients have laryngeal edema but only 5%<br />

having severe obstruction


92<br />

-If you extubate and hear stridor with poor respiration<br />

then consider edema and acutely give racemic Epi<br />

nebs prn stridor, keep HOB elevated to 90°, and give<br />

solumedrol 60 mg IV Q6 hours x 48 hours<br />

• Vocal Cord Dysfunction (VCD)<br />

- This is a long term complication: Need ENT<br />

evaluation<br />

Weaning MV<br />

When pts are clinically improved, assess the following criteria<br />

for extubation:<br />

• Original condition requiring intubation has been reversed<br />

or improved<br />

• During sedation vacation, patients are awake and alert<br />

• Hemodynamically Stable (HR60mm, no<br />

evidence of myocardial ischemia) while on minimum to no<br />

vasopressor support and no sedation<br />

• Stable Oxygenation (PaO2>60mm and O2Sat>92%)<br />

while on minimum non-toxic oxygenation settings<br />

(PEEP


93<br />

- Sustained changes in the heart rate of 20 percent in<br />

either direction<br />

- A systolic blood pressure greater than 180 mm Hg<br />

or less than 90 mm Hg<br />

- Increased anxiety<br />

- Diaphoresis<br />

If pts pass SBT then write orders:<br />

• Check Cuff Leak Test prior to extubation (Patients<br />

without a cuff leak are at increased risk for post-extubation<br />

stridor)<br />

• Respiratory to Extubate (How is it done? HOB elevated<br />

to 90°, pull ETT, suction, listen for stridor, suction, then<br />

Face Mask/NC)<br />

• Place pt on 6L NC and then proceed w/ O2 Protocol<br />

• Incentive Spirometry (IS) Q2hrs while awake<br />

• Med Nebs: IPPB A/A nebs Q4 hours x 48 hours<br />

(Intermittent Positive Pressure Breathing (IPPB)) which is<br />

mainly used to treat atelectasis after surgery or postextubation<br />

to improve inspiratory capacity<br />

• Consider BiPAP if patient is high risk for re-intubation as<br />

post-extubation BiPAP has been shown to decrease reintubation<br />

• Swallow Study and Advance Diet as tolerated if passes<br />

• PT/OT<br />

If pts fail SBT then assess cause (see below) and retry SBT<br />

Qday if you feel patient is still clinically prepared.<br />

F Fluid overload: Diurese as able<br />

A Airway resistance: Check if ET tube is too small or<br />

obstructed<br />

I Infection: Treat as indicated<br />

L Lying down, bad V/Q mismatch: Elevate head of bed<br />

T Thyroid, toxicity of drugs: check TFT’s, check med list<br />

O Oxygen: Increase FiO2 as patient is taken off<br />

ventilator<br />

W Wheezing: treat with nebs/steroids as needed<br />

E Electrolyte disturbances: Correct K, Mg, Phos,<br />

Calcium<br />

A Anti-inflammatory needed?: Consider steroids in<br />

asthma/COPD<br />

N Neuromuscular disease, neuro status compromised


94<br />

PLEURAL EFFUSION<br />

Thoracentesis needed if effusion >1 cm in decubitus view; also<br />

patient with fever, chest pain, unilateral effusion, or new<br />

effusion. Parapneumonic effusions should be tapped ASAP.<br />

Transudate versus Exudate:<br />

1. Light’s criteria:TP eff/TP serum=>0.5, LDH eff/LDH<br />

serum >0.6, or LDH eff > 2/3 upper limit of normal of<br />

LDH serum (Best sensitivity but will misidentify 25%<br />

of transudates as exudates). Light’s criteria is most<br />

used and clinically applicable.<br />

2. Exudative criteria with better specificity: two test rule<br />

(pleural fluid cholesterol >45 and pleural fluid LDH<br />

>0.45 times upper limit of normal serum LDH), or<br />

three test rule (pleural fluid protein >2.9, pleural fluid<br />

cholesterol >45, and pleural fluid LDH >0.45 times<br />

upper limit of normal serum LDH)<br />

Complicated versus Uncomplicated Parapneumonic<br />

effusion:<br />

1. Complicated=positive gram stain or culture or pH


95<br />

PULMONARY EMBOLUS (PE)<br />

Evaluating using Dichotomized Wells clinical PE<br />

Probability for Algorithm using CT angiography<br />

(CTA)<br />

Variable Point Score<br />

Symptoms and signs of DVT 3<br />

PE more likely than alternative<br />

diagnosis<br />

3<br />

HR >100 beats/ minute 1.5<br />

Recent immobilization or surgery<br />

(


96<br />

• All other combinations with V/Q scan requires further<br />

testing (ie, serial venous ultrasonography and pulmonary<br />

angiography)<br />

Treatment<br />

• Reserve TPA for patients with hemodynamic<br />

compromise (cardiogenic shock, persistent arterial<br />

hypotension, or both). If hemodynamically unstable, start<br />

on heparin drip immediately and prepare for thrombolytics.<br />

• Start patients with intermediate-risk or high risk PE on<br />

unfractionated heparin drip per protocol or enoxaparin at 1<br />

mg/kg SC BID (can use fondaparinux in HIT patients).<br />

Patient needs to be on enoxaparin or fondaparinux<br />

eventually for outpatient bridge to long term<br />

anticoagulation therapy. These agents are generally<br />

preferred because they are easier to administer and are<br />

associated with lower rates of heparin-induced<br />

thrombocytopenia<br />

• If patient has HIT, can use argatroban or lepirudin drip<br />

instead of heparin drip (there are protocols for both).<br />

• Start patient on warfarin when heparin assay therapeutic<br />

or after 1 st does of LMWH; goal INR 2-3. Need to overlap<br />

treatment-usually 2-3 days after INR is therapeutic, and<br />

then can discontinue heparin.<br />

• Send patient to IR for IVC filter placement if<br />

contraindication to anticoagulation, treatment failure, or<br />

bleeding.<br />

References:<br />

1. Fauci, AS, Martin, JB Braunwald, E. et al (Eds). Harrison’s<br />

Principles of Internal Medicine. 14 th Edition. McGraw Hill, New York,<br />

1998.<br />

2. Konstantinides, S. Acute Pulmonary Embolism. N Engl J Med 2008;<br />

359:2804-2813.<br />

3. Esteban, A, Frutos, F, Tobin, MJ, et al. A Comparison of Four<br />

Methods of Weaning Patients from Mechanical Ventilation. N Engl J<br />

Med 1995; 332:345-350.<br />

4. Manthous, C, Schmidt, G, Hall, J. Liberation from Mechanical<br />

Ventilation: A Decade of Progress. Chest 1998; 114:886-901.<br />

5. Schmidt, SL, Hyzy, RC. Overview of Mechanical Ventilation. In:<br />

UpToDate, Basow, D (Ed), UpToDate, Waltham, MA, 2009.<br />

6. Tobin, MJ. Advances in Mechanical Ventilation. N Engl J Med 2001;<br />

344:1986-96.<br />

7. Ventilation with lower tidal volumes as compared with traditional<br />

tidal volumes for acute lung injury and acute respiratory distress<br />

syndrome. The Acute Respiratory Distress Syndrome Network. N Engl<br />

J Med 2000; 342:1301-8.


97<br />

RADIOLOGY<br />

RADIOLOGY HINTS<br />

IF YOU’RE THINKING THIS: ORDER THIS<br />

FIRST<br />

Shortness of breath CXR*<br />

Chest pain CXR*<br />

Volume overload CXR*<br />

Obstruction Supine/upright<br />

KUB<br />

Acute abdomen, bowel<br />

perforation<br />

Abdomen<br />

obstructive series<br />

After subclavian line placement pCXR to r/o PTX<br />

DVT (pain, swelling) Lower extremity<br />

Doppler<br />

ultrasound<br />

PE (Consider<br />

checking ddimer<br />

+/- doing LE<br />

Doppler first) --<br />

CTA chest (CT<br />

chest PE protocol)<br />

AMS CT head<br />

Carotid stenosis Carotid Doppler<br />

ultrasound<br />

Stroke CT head<br />

WITHOUT<br />

contrast, then MRI<br />

brain


98<br />

F/U pulmonary nodules CT without IV<br />

contrast<br />

Abdominal pain CT abdomen with<br />

oral and IV<br />

contrast<br />

Cirrhosis, elevated LFT’s,<br />

jaundice<br />

RUQ ultrasound<br />

Hepatomegaly,<br />

Abdominal<br />

splenomegaly<br />

ultrasound<br />

Hepatocellular carcinoma MRI liver<br />

Confirm hemangiomas MRI<br />

GB- Chronic<br />

cholecystitis/gallstones/b<br />

iliary colic<br />

Ultrasound<br />

GB- Acute cholecystitis Ultrasound;<br />

consider HIDA if<br />

U/S equivocal<br />

Kidney stones Renal stone<br />

protocol CT<br />

Renal disease, elevated<br />

Renal Ultrasound<br />

creatinine<br />

Pancreas (complications<br />

of pancreatitis,<br />

pancreatic cancer)<br />

CT Abdomen with<br />

contrast<br />

Adrenal mass Adrenal mass<br />

protocol CT or<br />

MRI<br />

Acute GI bleed < .5-1.0<br />

Tagged RBC<br />

ml/min<br />

Acute GI bleed < 2 ml/min Endoscopy<br />

Acute GI bleed 2 ml/min Mesenteric<br />

Angiography<br />

Mesenteric Ischemia CT Angiogram<br />

Abdomen/Pelvis<br />

Appendicitis Ultrasound (if<br />

thin), CT<br />

Abdomen/Pelvis<br />

with oral and IV<br />

contrast


Superficial Abscess/Mass<br />

Abscess/Mass/<br />

Infection<br />

99<br />

Ultrasound<br />

CT chest,<br />

abdomen or pelvis<br />

with oral and IV<br />

contrast<br />

Trauma CT<br />

Tumor Staging CT with IV<br />

contrast<br />

Testicular Mass/Torsion Testicular<br />

Ultrasound<br />

Myositis MRI<br />

Osteomyelitis MRI/ Indium /<br />

Gallium<br />

Breast Mass Mammogram<br />

Dysphagia, non-cardiac<br />

chest pain, GERD<br />

GI ulcer, hiatal hernia,<br />

abdominal pain<br />

IBD, small bowel<br />

obstruction, small bowel<br />

mass, malabsorption<br />

Large bowel obstruction,<br />

LLQ pain, constipation,<br />

diarrhea<br />

Biopsy (peripheral lung<br />

mass, liver, renal, lymph<br />

node, etc)<br />

Gastrostomy tube, IVC<br />

Filter<br />

Esophagogram<br />

UGI<br />

Small bowel follow<br />

through<br />

Barium enema<br />

Consult biopsy<br />

service<br />

Consult IR<br />

Ovarian Torsion Ultrasound<br />

Endocarditis TEE<br />

Pulm HTN/CHF TTE


100<br />

*With CXR: PA/lateral if pt able to stand; portable if unable to<br />

go to radiology or if STAT<br />

If you have any questions about what test to order, feel free to<br />

call and ask. Also, when you write the order for an exam, write<br />

an indication including what you are worried about and why. It<br />

will help make sure your test gets done correctly and that your<br />

specific concern is addressed in the report. This will save you<br />

from having to track someone down later if the report doesn’t<br />

address your main concern.<br />

To hear dictations of radiology reports: call “2 X-RAY” (29729).<br />

You will be prompted to enter your “logon ID” (your 4-digit<br />

dictation number), followed by #. Then you will be prompted for<br />

your password (1 st time is your 4-digit dictation number, but it<br />

will prompt you to change it), followed by #. Then you put in the<br />

pt’s date of birth, followed by #. The most recent dictation plays<br />

first.


101<br />

RENAL<br />

ACID/BASE DISTURBANCES<br />

Quick guide to acid/base disturbances:<br />

1. Look at the Ph:<br />

7.40 = normal<br />

7.45 = alkalemia<br />

Decide primary disorder (this is if compensated):<br />

Primary disorder pH HCO3 paCO2<br />

Metabolic<br />

acidosis<br />

↓ ↓ ↓<br />

Metabolic<br />

alkalosis<br />

↑ ↑ ↑<br />

Resp acidosis ↓ ↑ ↑<br />

Resp alkalosis ↑ ↓ ↓<br />

2. Determine if degree of compensation is appropriate:<br />

Metabolic acidosis: PCO2 = HCO3 + 15 (or the Winter’s<br />

Equation — pCO2 = 1.5(HCO3) + 8 +/- 2)<br />

Also, with metabolic acidosis the last decimal digits of<br />

the pH should equal pCO2 +/-2.<br />

Metabolic alkalosis: Increase in PaCO2 = 0.75 x change<br />

in HCO3 (HCO3 + 15 works fairly well)<br />

Respiratory acidosis:<br />

Acute: for every increase in 10 in pCO2, there is an<br />

increase in HCO3 by 1<br />

Chronic: for every increase in 10 in pCO2, there is an<br />

increase in HCO3 by 4<br />

Respiratory alkalosis:<br />

Acute: for every decrease in 10 in pCO2, there is a<br />

decrease in HCO3 by 2<br />

Chronic: for every decrease in 10 pCO2, there is a<br />

decrease in HCO3 by 5<br />

If not what expected, consider a mixed disorder.


102<br />

3. Calculate anion gap by Na- Cl- HCO3 (nl 8-12; if albumin<br />

is low reduce normal range by 2-3 for each 1 gm reduction<br />

of albumin below normal):<br />

Causes of AGMA: KUSMALE (ketones, uremia,<br />

salicylates, methanol, paraldehyde, lactic acidosis, or<br />

ethylene glycol) or GOLDMARK-paper submitted by<br />

Mehta et al (glycols, oxyproline, L-lactate, D-lactate,<br />

Methanol, Aspirin, Renal, Ketoacidosis)<br />

If anion gap, consider the following: urine and serum<br />

ketones, renal function, lactate, Utox, plasma osmolal gap.<br />

Osmolal gap: “Delta Osmoles” =measured plasma<br />

osmolality - calculated osmolality<br />

Calculated osmolality = (2xNa)+(glucose/18)+(BUN/2.8)<br />

Osmolal gap >15 suggests methanol or ethylene glycol<br />

If anion gap is decreased, you should suspect a<br />

decreased albumin or disorders that increase<br />

“unmeasured” cations such as multiple myeloma, extreme<br />

hypercalcemia, hypermagnesemia, lithium.<br />

4. If there is a high anion gap, then calculate how much it is<br />

increased above the normal range (ie, Anion Gap Increase<br />

= observed anion gap-expected anion gap (8 - 12 if<br />

albumin is normal)<br />

Increase in Gap + measured HCO3 should = about 24<br />

(The gap should go up about the same amount the HCO3<br />

goes down)<br />

• If this is >24 consider concomitant metabolic<br />

alkalosis or severe chronic respiratory acidosis<br />

• If this is


103<br />

ACUTE KIDNEY INJURY<br />

Acute Kidney Injury Network (AKIN) definition of<br />

AKI: (Have offered a modification/update of RIFLE)<br />

The proposed diagnostic criteria are an abrupt (within 48<br />

hours):<br />

• Absolute increase in the serum creatinine concentration<br />

of ≥0.3 mg/dL from baseline, or<br />

• A percentage increase in the serum creatinine<br />

concentration of ≥50 percent,<br />

• Or oliguria of less than 0.5 mL/kg per hour for more than<br />

six hours.<br />

The diagnostic criteria should be applied only after volume<br />

status has been optimized and urinary tract obstruction has<br />

been ruled out if oliguria was used as the sole diagnostic<br />

criterion.<br />

The Acute Kidney Injury Network also includes a staging<br />

system that correlates to the RIFLE criteria. Stage 1 (risk),<br />

stage 2 (injury), and stage 3 (failure) are included and loss and<br />

ESRD are considered outcomes.<br />

RIFLE criteria proposed by the Acute Dialysis<br />

Quality Initiative (ADQI):<br />

• Risk — 1.5-fold increase in the serum creatinine or GFR<br />

decrease by 25 percent or urine output


104<br />

Consider obtaining the following history or ordering<br />

the following labs/studies:<br />

• History: Any history of contrast, NSAIDS, nephrotoxins,<br />

intravascular volume depletion (vomiting, diarrhea,<br />

hemorrhage, diuretics, third spacing, burns), sepsis,<br />

recent procedure or surgery (angiography, if CABG-check<br />

aorta cross clamp time, check anesthesia log for any<br />

episodes of hypotension), medication history, history of<br />

renal disease, history of vasculitis<br />

• UA with microscopy (simple test to perform and can<br />

give you very valuable information)<br />

• Consider bladder outlet obstruction. If Foley is in place,<br />

is it blocked?<br />

• Renal ultrasound to evaluate for hydronephrosis<br />

• Urine spot Na, Cr at same time as BMP to calculate<br />

FENa if oliguric<br />

• Urine eosinophils if thinking about interstitial<br />

nephritis/cholesterol emboli/ATN<br />

Treatment:<br />

• Treat underlying cause<br />

• IV Fluids if needed<br />

• Avoid nephrotoxins/contrast<br />

• Renally dose medications<br />

• See indications for renal replacement therapy below<br />

BASIC ELECTROLYE REPLACEMENT<br />

Can replete as below and then look for underlying cause of<br />

deficiency.<br />

Calcium: Check ionized calcium, then give one to two<br />

amps of Calcium gluconate IVPB if low<br />

Magnesium: Each 1 gram given increases the serum level<br />

by about 0.1<br />

MgSO4 comes as a 50% solution in 2cc amps<br />

(2cc = 1 gm MgSO4 = 98 mg Mg = 4 mM Mg = 8 mEq<br />

Mg)<br />

Send blood and urine for Mg and Cr before replacing to<br />

check FEx Mg


105<br />

Mg


106<br />

Remember to adjust this is they have an elevated creatinine,<br />

low weight, etc.<br />

If patient taking a diet:<br />

K 3.6 to 3.8 50 meq K PO x1<br />

K 3.3 to 3.5 50 meq K PO q 2 hours x 2 doses<br />

K 2.8 to 3.2 50 meq K PO q 2 hours x 3 doses<br />

K


107<br />

CHRONIC KIDNEY DISEASE<br />

Stage GFR<br />

I >90<br />

II 60-89<br />

III 30-59<br />

IV 15-29<br />

V


108<br />

disease (GFR of 30 to 59 mL/min per 1.73 m2), 70 to 110<br />

pg/mL for those with stage 4 disease (GFR of 15 to 29<br />

mL/min per 1.73 m2), 150 to 300 pg/mL for stage 5<br />

disease (dialysis or GFR of less than 15 mL/min per 1.73<br />

m2)<br />

• Hypertension: Goal blood pressure is at least


Hypovolemic<br />

Hyponatremia<br />

EABV low<br />

Renal losses<br />

Diuretics/Salt<br />

Wasting<br />

GI losses<br />

Diarrhea/<br />

Vomiting<br />

Bleeding<br />

Other<br />

Pancreatitis<br />

3 rd Spacing<br />

(Burns,etc.)<br />

Treatment:<br />

Volume replete<br />

with<br />

• NS<br />

• Blood<br />

• Colloid<br />

Uosm100<br />

• SIADH (also see Una high,<br />

Plasma BUN and uric acid low<br />

• Hypothyroidism<br />

• Glucocorticoid deficiency<br />

Treatments:<br />

• Fluid restriction<br />

• Hypertonic saline<br />

• Demeclocycline


Anuria: UOP


111<br />

fluid pulled off and into the peritoneum. Access is through a<br />

temporary or permanent catheter.<br />

Choice of therapy:<br />

• Continuous Renal Replacement Therapy (CRRT):<br />

-Continuous venovenous hemodialysis (CVVHD)<br />

-Continuous arteriovenous hemodialysis (CAVHD)<br />

-Continuous venovenous hemodialysis with filtration<br />

(CVVHDF)<br />

-Continuous arteriovenous hemodialysis with filtration<br />

(CAVHDF)<br />

-Continuous venovenous hemofiltration (CVVHF)<br />

-Continuous arteriovenous hemofiltration (CAVHF)<br />

• Intermittent Hemodialysis (IDH)<br />

• Peritoneal Dialysis (PD)<br />

Timing of therapy: Optimal timing of RRT in patients with<br />

AKI remains to be clearly elucidated. Some retrospective and<br />

uncontrolled studies suggest that prophylactic dialysis prior to<br />

the development of overt uremia among patients with<br />

progressive AKI may be associated with reduced mortality.<br />

Some show no difference in mortality. Only one prospective<br />

randomized trial has been done to evaluate the timing of<br />

CRRT and it showed no survival benefit in early versus late<br />

CVVHF. Timing is therefore very much practitioner based.<br />

Choice of modality:<br />

• Hemofiltration versus hemodialysis: HF can more quickly<br />

clear larger molecular weight molecules. However, no trials<br />

have shown improved clinical outcomes with either modality<br />

over the other.<br />

• CRRT versus IHD: Current data suggests that survival and<br />

renal recovery are equal in patients who undergo CRRT versus<br />

IHD. Data do not support the superiority of any particular<br />

mode of RRT in patients with AKI.


112<br />

OUTPATIENT CLINIC GUIDE<br />

THE PATIENT ENCOUNTER<br />

• Check-in and vitals are completed by the medical<br />

assistant (MA).<br />

• All charts are viewed via Baylor EMR. Go to “Clinic Visit<br />

History.”<br />

• Once you have completed your clinic visit, complete the<br />

following checklist:<br />

- Clinic Visit form, only middle and right column is<br />

required.<br />

- Universal Medication List at each visit with resident<br />

signature.<br />

- Lab Request form for same day, one week prior to<br />

next visit, or both.<br />

- Fill out any consult or imaging forms as needed.<br />

- Retrieve, record on log, and place med samples in<br />

bag with “Instructions” form placed inside and patient<br />

label placed on outside of bag.<br />

- Write all prescriptions with DPS and DEA # on each<br />

Rx<br />

- Return appointment/referral form.<br />

- Dictate Clinic Visit. Dictation “type” = ‘98’.<br />

- Find a nurse to “check-out” by reviewing each<br />

above item with RN. The nurse will then dispense<br />

meds, prescriptions, and papers to the patient.<br />

RESOURCES<br />

• The clinic chiefs (two residents) accept clinic patients bimonthly.<br />

<strong>BUMC</strong> then assigns them to category 1 through<br />

8, category 1 being least funded. There are various<br />

resources that can be offered to the patients based on<br />

these categories.<br />

• The patient’s category and insurance information are<br />

located on the face sheet.<br />

Referrals<br />

Specialties offered via Resident Clinic and open to all clinic<br />

patients:<br />

• Renal, Cards, Oncology, GI, OB-Gyn, General Surgery,


113<br />

Colorectal Surgery, and Plastic Surgery � Fill out consult<br />

form.<br />

• Dermatology: Dr. Menter sees un-funded patients in the<br />

resident clinic weekly, and gets booked in advance. � Fill<br />

out consult form.<br />

• PM&R, Physical Therapy � Fill out consult form.<br />

Specialties not offered via Resident Clinic:<br />

• Psychiatry:<br />

- Funded patients � <strong>BUMC</strong> Psychiatry. Make<br />

referral.<br />

- Un-funded � Northstar. Consult Social Work to<br />

arrange.<br />

• Others (eg Ophtho, Urology):<br />

- Funded � <strong>BUMC</strong> referral.<br />

- Un-funded and in-county � Parkland. Consult<br />

Social Work.<br />

• <strong>BUMC</strong> also offers Podiatry and COPD clinic, but<br />

requires insurance.<br />

Dentistry<br />

• The Dental School Clinic provides dental services at a<br />

reduced cost.<br />

• The patient will initially need to call the dental clinic at<br />

(214) 823-1376, Wednesdays from 9-10:30 am. There is a<br />

non-refundable screening fee of $54.00. To refer, let the<br />

RN know during check-out.<br />

Coumadin Clinic<br />

• Run by our Clinical Pharmacist Jennifer.<br />

Medications<br />

• Formulary medications (list posted on wall) for Category<br />

I, II, and III patients.<br />

• Samples available for all clinic patients.<br />

• Insulin (70/30 and Levemir). Write Rx and consult clinic<br />

pharmacist.<br />

• $4 Walmart List (see next section in book for full listing)<br />

Insulin-dependent diabetes mellitus<br />

When starting insulin, the clinic offers these resources:<br />

• Insulin at no cost for un-funded patients. Write Rx and<br />

pharmacy consult. Pharmacist dispenses and provides<br />

patient education.<br />

• Glucometers and strips for un-funded patients. Write Rx<br />

and social work consult.


114<br />

• Diabetes Clinic<br />

- Requires referral by resident. Form is available on<br />

wall.<br />

- Can titrate insulin without resident's signature or<br />

resident can opt to titrate insulin him/herself.<br />

Social Work - Vendetta (mostly for un-funded patients)<br />

• Off-campus specialist referrals (eg, Parkland Clinics)<br />

• Meds not offered on formulary or Walmart $4 List<br />

• Medical supplies (eg glucometers/strips)<br />

• Patient Transportation<br />

• Counseling<br />

• <strong>Home</strong> care needs<br />

• Short-term psycho-social intervention for patients, (eg<br />

emergency shelter, severe financial need, etc.)<br />

Interpreter Service:<br />

A phone service is available. The phone is in the nurse’s<br />

station. Take the phone to your exam room, press redial, give<br />

the code “<strong>BUMC</strong>” and state the language requested.<br />

Emergency psychiatric evaluation and observation (eg<br />

acutely suicidal patient)<br />

• Inform the charge nurse who will contact the ED Psych<br />

services.<br />

• If the patient is on the phone with you, inform them that<br />

you or they need to call 911, and stay on the phone until<br />

an EMT arrives.<br />

HOW TO ORDER<br />

• IVFs or PO/IV meds in clinic = order using physician<br />

order sheet. Give to RN.<br />

• Screening tests: All order sheets are on wall in<br />

resident’s area.<br />

- Mammogram = mammo order sheet<br />

- Bone density scan = on Radiology form, write in<br />

"Bone density scan" for type of study.<br />

- Colonoscopy = GI referral on Consult form.<br />

- Eye exam = if patient is un-funded and in-county,<br />

write social work order to refer to Parkland<br />

Opthalmology Resident clinic (long wait to get<br />

appointment, patients will be called.)<br />

• MRI/CT scans = Fill out Radiology form.<br />

• Flu/Pneumovax = write on Encounter form (under<br />

medication administration).


115<br />

• Social work: Circle Social Work on "Return Visit" sheet,<br />

and write a summary of what you need.<br />

HOW TO ADMIT A PATIENT DIRECTLY<br />

FROM CLINIC<br />

1. Discuss with attending before admitting.<br />

2. Call admitting resident and present the patient. If you are<br />

on wards, you will assume care of the patient the following<br />

morning.<br />

3. Inform charge RN and request bed type.<br />

4. Send patient to admitting desk.<br />

5. Fill out H&P and write brief admit orders for team.<br />

6. Dictate clinic note.<br />

URGENT CARE VISIT<br />

• If you need to see your patient on a non-clinic day for an<br />

urgent problem, contact the clinic to obtain an<br />

appointment.<br />

• For any patient emergency, advise them to go to the ER<br />

or call EMS immediately.<br />

WELL-WOMAN EXAM<br />

Once patient is gowned, have RN/MA bring tray for Pap smear<br />

and stay for breast exam.<br />

SIGNING DOCUMENTS<br />

• Labs/Imaging/Pathology results = Initial/Date each page<br />

and place folder in “Medical Records” pile at RN’s station.<br />

• No-shows = select action to be taken (eg re-schedule,<br />

call patient, discharge from clinic with attending’s consent)<br />

and place chart on counter across from Carolyn’s<br />

(scheduler) desk.<br />

• Phone messages and social work documents = After<br />

returning call and documenting your encounter, place<br />

chart in black tray behind resident’s area.


116<br />

$4 Rx LIST<br />

(Most have 90 day supply for $10)<br />

Please refer to your own prescribing reference when writing your<br />

Rx’s<br />

Allergies & Cold and Flu<br />

Benzonatate 100mg cap<br />

Ceron DM syrup<br />

C-Phen drops* (ml bottle)<br />

Dex PC syrup<br />

Loratadine 10mg tab<br />

Promethazine DM syrup<br />

Antibiotic Treatments<br />

Amoxicillin 125mg/5ml susp<br />

(80ml bottle)(100ml bottle)<br />

(150ml bottle)<br />

Amoxicillin 200mg/5ml susp<br />

(50ml bottle) (75ml bottle)*<br />

(100ml bottle)*<br />

Amoxicillin 250mg/5ml susp<br />

(80ml bottle)(100ml bottle)<br />

(150ml bottle)<br />

Amoxicillin 400mg/5ml susp<br />

(50ml bottle)(75ml bottle)*<br />

(100ml bottle)*<br />

Amoxicillin 250mg cap/500mg<br />

cap<br />

Amoxil 50mg/ml drops* (ml<br />

bottle)<br />

Cephalexin 250mg cap/500mg<br />

cap<br />

Ciprofloxacin 250mg tab/500mg<br />

tab<br />

Doxycycline Hyclate 50mg<br />

cap/100mg cap/100mg tab<br />

Erythromycin EC 250mg cap<br />

Metronidazole 250mg tab/500mg<br />

tab<br />

Penicillin VK 250mg tab<br />

Penicillin VK 125mg/5ml susp<br />

(100ml bottle)(200ml bottle)<br />

Penicillin VK 250mg/5ml susp<br />

(100ml bottle)<br />

SMZ-TMP 200mg-40mg/5ml<br />

susp<br />

SMZ-TMP 400mg-80mg tab<br />

SMZ-TMP DS 800mg-160mg tab<br />

Tetracycline 250mg cap/500mg<br />

cap<br />

Arthritis & Pain<br />

Allopurinol 100mg tab<br />

Baclofen 10mg tab<br />

Colchicine 06mg tab<br />

Cyclobenzaprine 5mg tab/10mg<br />

tab<br />

Dexamethasone 0.5mg<br />

tab/0.75mg tab/4mg tab<br />

Diclofenac DR 75mg tab<br />

Ibuprofen 100mg/5ml susp<br />

Ibuprofen 400mg tab/600mg<br />

tab/800mg tab<br />

Indomethacin 25mg cap<br />

Meloxicam 7.5mg tab/15mg tab<br />

Naproxen 375mg tab/500mg tab<br />

Piroxicam 20mg cap<br />

Salsalate 500mg tab<br />

Asthma<br />

Albuterol 2mg tab/4mg tab<br />

Albuterol 2mg/5ml syrup<br />

Albuterol 0.5% nebulizer soln<br />

(20ml bottle)<br />

Albuterol 0.083% nebulizer soln*<br />

(25x3ml vials)<br />

Ipratropium 0.02% nebulizer<br />

soln* (25x25ml vials)<br />

Cholesterol<br />

Lovastatin 10mg tab/20mg tab<br />

Pravastatin 10mg tab/20mg<br />

tab/40mg tab<br />

Diabetes<br />

Chlorpropamide 100mg tab<br />

Glimepiride 1mg tab/2mg<br />

tab/4mg tab<br />

Glipizide 5mg tab/10mg tab<br />

Glyburide 2.5mg tab<br />

Glyburide 5mg tab (blue)/(green)<br />

Glyburide, micronized 3mg<br />

tab/6mg tab<br />

Metformin 500mg tab/1000mg<br />

tab<br />

Metformin 500mg ER tab


Ear Health<br />

Antipyrine/Benzocaine otic (10ml<br />

bottle)<br />

Fungal Infections<br />

Fluconazole 150mg tab<br />

Nystatin/Triamcin cream (15gm<br />

tube)<br />

Nystatin/Triamcin ointment<br />

(15gm tube)<br />

Nystatin cream (15gm tube)<br />

Nystatin ointment (15gm tube)<br />

Terbinafine 250mg tab<br />

Gastrointestinal Health<br />

Belladonna Alkaloid/PB tab<br />

Cimetidine 800mg tab<br />

Cytra2 solution<br />

Dicyclomine 10mg cap/20mg tab<br />

Famotidine 20mg tab<br />

Lactulose syrup<br />

Metoclopramide 10mg tab<br />

Metoclopramide syrup<br />

Promethazine 25mg tab<br />

Promethazine plain syrup<br />

Ranitidine 150mg tab/300mg tab<br />

Glaucoma & Eye Care<br />

Atropine Sulfate 1% op soln (5ml<br />

bottle)<br />

Bacitracin op ointment (35gm<br />

tube)<br />

Erythromycin op ointment (35gm<br />

tube)<br />

Gentamicin 0.3% op soln (5ml<br />

bottle)<br />

Levobunolol 0.5% op soln (5ml<br />

bottle)<br />

Neomycin/Polymyxin/Dexameth<br />

asone 0.1% op ointment (35gm<br />

tube)<br />

Neomycin/Polymyxin/Dexameth<br />

asone 01% op susp (5ml bottle)<br />

Pilocarpine 1% op soln (15ml<br />

bottle)<br />

Pilocarpine 2% op soln (15ml<br />

bottle)<br />

Polymyxin Sulfate/TMP op soln*<br />

(10ml bottle)<br />

Sulfacet Sodium 10% op soln<br />

(15ml bottle)<br />

Timolol Maleate 0.25% op soln<br />

(5ml bottle)<br />

117<br />

Timolol Maleate 0.5% op soln<br />

(5ml bottle)<br />

Tobramycin 0.3% op soln (5ml<br />

bottle)<br />

Heart Health & Blood Pressure<br />

Amiloride-HCTZ 5mg-50mg tab<br />

Atenolol-Chlorthalidone 50mg-<br />

25mg tab/100mg-25mg tab<br />

Atenolol 25mg tab/50mg<br />

tab/100mg tab<br />

Benazepril 5mg tab/10mg<br />

tab/20mg tab/40mg tab<br />

Bisoprolol-HCTZ 25mg-625mg<br />

tab/5mg-625mg tab/10mg-<br />

625mg tab<br />

Bumetanide 0.5mg tab/1mg tab<br />

Captopril 125mg tab/25mg<br />

tab/50mg tab/100mg tab<br />

Carvedilol 3.125mg tab/6.25mg<br />

tab/12.5mg tab/25mg tab*<br />

Chlorthalidone 25mg tab/50mg<br />

tab<br />

Clonidine 0.1mg tab/0.2mg tab<br />

Digoxin 0.125mg tab/0.25mg tab<br />

Diltiazem 30mg tab/60mg<br />

tab/90mg tab*/120mg tab<br />

Doxazosin 1mg tab/2mg<br />

tab/4mg tab/8mg tab<br />

Enalapril-HCTZ 5mg-12.5mg tab<br />

Enalapril 25mg tab/5mg<br />

tab/10mg tab/20mg tab<br />

Furosemide 20mg tab/40mg<br />

tab/80mg tab<br />

Guanfacine 1mg tab<br />

Hydralazine 10mg tab/25mg tab<br />

Hydrochlorothiazide (HCTZ)<br />

12.5mg cap*/25mg tab/50mg tab<br />

Indapamide 1.25mg tab/2.5mg<br />

tab<br />

Isosorbide Mononitrate 30mg ER<br />

tab/60mg ER tab<br />

Lisinopril-HCTZ 10mg-12.5mg<br />

tab/20mg-12.5mg tab*/20mg-<br />

25mg tab*<br />

Lisinopril 2.5mg tab/5mg<br />

tab/10mg tab/20mg tab<br />

Methyldopa 250mg tab*/500mg<br />

tab*<br />

Metoprolol Tartrate 25mg<br />

tab/50mg tab/100mg tab*<br />

Nadolol 20mg tab/40mg tab


Nitroquick 0.3mg sub tab* (100<br />

count bottle)†<br />

Nitroquick 0.4mg sub tab* (25<br />

count)†<br />

Nitroquick 0.4mg sub tab* (100<br />

count bottle)<br />

Pindolol 5mg tab/10mg tab<br />

Prazosin HCL 1mg cap/2mg<br />

cap/5mg cap<br />

Propranolol 10mg tab/20mg<br />

tab/40mg tab/80mg tab<br />

Sotalol HCL 80mg tab<br />

Spironolactone 25mg tab<br />

Terazosin 1mg cap/2mg<br />

cap/5mg cap/10mg cap<br />

Triamterene-HCTZ 37.5mg-<br />

25mg cap/37.5mg-25mg<br />

tab/75mg-50mg tab<br />

Verapamil 80mg tab/120mg tab<br />

Warfarin 1mg tab/2mg tab/2.5mg<br />

tab/3mg tab/4mg tab/5mg<br />

tab*/6mg tab/7.5mg tab/10mg<br />

tab<br />

Mental Health<br />

Amitriptyline 10mg tab/25 mg<br />

tab/50mg tab/75mg tab/100mg<br />

tab<br />

Benztropine 2mg tab<br />

Buspirone 5mg tab/10mg tab*<br />

Carbamazepine 200mg tab<br />

Citalopram 20mg tab/40mg tab<br />

Doxepin HCL 10mg cap/25mg<br />

cap/50mg cap/75mg cap/100mg<br />

cap<br />

Fluoxetine 10mg tab*/10mg<br />

cap/20mg cap/40mg cap<br />

Fluphenazine 1mg tab<br />

Haloperidol 0.5mg tab/1mg<br />

tab/2mg tab/5mg tab<br />

Lithium Carbonate 300mg cap<br />

Nortriptyline 10mg cap/25mg<br />

cap<br />

Paroxetine 10mg tab*/20mg tab*<br />

Prochlorperazine 10mg tab<br />

Thioridazine 25mg tab/50mg tab<br />

Thiothixene 2mg cap<br />

Trazodone 50mg tab/100mg<br />

tab/150mg tab<br />

Trihexyphenidyl 2mg tab<br />

118<br />

Skin Conditions<br />

Benzoyl Peroxide 4% creamy<br />

wash (1701ml bottle)<br />

Betamethasone Dipropionate<br />

0.05% cream (45gm tube)<br />

Betamethasone Valerate 0.1%<br />

cream (15gm tube)<br />

Betamethasone Val 0.1% cream<br />

(45gm tube)<br />

Fluocinolone Acet 0.01% soln<br />

(60ml bottle)†<br />

Fluocinonide 0.05% cream<br />

(15gm tube)†<br />

Fluocinonide 0.05% cream (gm<br />

tube)†<br />

Gentamicin 0.1% cream (15gm<br />

tube)<br />

Gentamicin 0.1% ointment<br />

(15gm tube)†<br />

Hydrocortisone 1% cream<br />

(2835-g tube)†<br />

Hydrocortisone 25% cream (gm<br />

tube)†<br />

Selenium Sulfide 25% lotion*<br />

(120ml bottle)†<br />

Silver Sulfadiazine 1% cream*<br />

(50gm tube)<br />

Triamcinolone 0.025% cream<br />

(15gm tube)†(80gm tube)†<br />

Triamcinolone 0.1% cream<br />

(15gm tube)† (80gm tube)†<br />

Triamcinolone 0.1% ointment<br />

(15gm tube)† (80gm tube)†<br />

Triamcinolone 0.5% cream<br />

(15gm tube)†<br />

Thyroid Conditions<br />

Levothyroxine 25mcg tab/50mcg<br />

tab/75mcg tab/88mcg<br />

tab/100mcg tab/112mcg<br />

tab/125mcg tab/137mcg<br />

tab/150mcg tab/175mcg<br />

tab*/200mcg tab*<br />

Viruses<br />

Acyclovir 200mg cap<br />

Vitamins & Nutritional Health<br />

Folic Acid 1mg tab<br />

Klorcon 8 8mEq ER tab<br />

Klorcon 10 10mEq ER tab<br />

Klorcon M10 10mEq tab<br />

Mag 64 64mg tab


Magnesium Oxide 400mg tab<br />

Prenatal Plus qty 30<br />

Potassium Chloride 10% liquid<br />

Sodium Fluoride .5mg chewable<br />

(120ct bottle)<br />

Women’s Health<br />

Estradiol 0.5mg tab/1mg<br />

tab/2mg tab<br />

Estropipate 0.75mg tab/1.5mg<br />

tab*<br />

Medroxyprogesterone Acetate<br />

25mg tab/5mg tab/10mg tab<br />

Alendronate SOD 35mg<br />

tab/70mg tab<br />

Clomiphene 50mg tab<br />

EST Estrogen/Methyl Testost<br />

HS tab/ DS tab<br />

Sprintec 28-day tab*<br />

Tri-Sprintec 28-day tab*<br />

Tamoxifen 10mg tab/20mg tab<br />

Other Medical Conditions<br />

Chlorhexidine Gluconate 0.12%<br />

soln<br />

Hydrocortisone AC 25mg<br />

suppositories<br />

Isoniazid 300mg tab<br />

Lidocaine 2% viscous solution<br />

(100ml bottle)†<br />

Megestrol 20mg tab*<br />

Methylpred 4mg tab<br />

Methylpred 4mg dose pak (21<br />

tablets)†<br />

Oxybutynin 5mg tab<br />

Phenazopyridine 100mg<br />

tab/200mg tab<br />

Prednisone 2.5mg tab/5mg<br />

tab/10mg tab/20mg tab<br />

Prednisone 5mg dose pak (21<br />

tablets)† (48 tablets)*†<br />

Prednisone 10mg dose pak (21<br />

tablets)† (48 tablets)*†<br />

119


120<br />

OTHER INFORMATION<br />

TOP TEN INTERN TIPS<br />

1. Be sure when you admit a patient, you ask the admitting<br />

attending how often they want to be contacted, and update<br />

them as they request.<br />

2. If you plan on discharging a patient, call the attending first<br />

thing in the am (esp TPC) so they can plan on seeing the<br />

patient early prior to discharge. If you can’t reach anyone from<br />

TPC and the patient has been set for discharge based on prior<br />

days’ attending, make sure to leave a message on the main<br />

line letting them know you plan on discharging the patient at X<br />

time unless you hear otherwise. ALWAYS CALL BEFORE<br />

YOU DISCHARGE.<br />

3. Dictate in a timely manner and review dictations/electronic<br />

signatures often so your attending does not end up on the B<br />

list and lose their admitting privileges. Go to medical records<br />

and have cookies and juice and review your dictations if you<br />

need to find a happy place!<br />

4. When you order an echo, write who needs to read it: Heart<br />

Place, CCT, or NTC. Look back at old echos and have the<br />

same group read it as did before.<br />

5. If you are waiting for a read on a radiologic study, look on<br />

centricity and see if it is dictated. If so, dial 2-XRAY and enter<br />

your user name/password to hear the dictation.<br />

6. Review the nurses notes from the previous night as well as<br />

PT/OT/Respiratory notes (located under a separate tab).<br />

Nutrition leaves notes at the back of the physician progress<br />

note section.<br />

7. Help out your other interns: Write prns on your admission<br />

orders and then sign cross-cover verbal orders when you<br />

round in the am so they don’t have to have them appear on<br />

their ESA’s and sign them electronically.<br />

8. If you need to call a patient from your cell phone or home<br />

phone, dial *67 and then the number.<br />

9. If you need to obtain medical records from an outside<br />

facility, write an order and the clerk will fax the request with the<br />

help of the nurse. Follow-up if the records do not come in a<br />

few days.<br />

10. Live, laugh, and learn … take the best care of your<br />

patients that you can and you will make it with flying colors!


121<br />

DUEWALL’S FAVORITE MNEMONICS<br />

• Pancreatitis:<br />

GET SMASHED<br />

Gallstones<br />

Ethanol<br />

Trauma<br />

Steroids<br />

Mumps<br />

Autoimmune<br />

Scorpion bites<br />

Hypercalcemia/triglyc<br />

eridemia<br />

ERCP (post-ERCP)<br />

Drugs (azathioprine,<br />

thiazides)<br />

• ACS treatment<br />

MONA BASH<br />

Morphine, Oxygen,<br />

Nitroglycerin, Aspirin,<br />

B-blocker, ACE-<br />

Inhibitor, Statin,<br />

Heparin<br />

• Alt. Mental Status<br />

MOVE STUPID<br />

Metabolic<br />

(Hypothyroid, Hepatic<br />

encephalopathy)<br />

Oxygen (hypoxia)<br />

Vascular (stroke)<br />

Electrolytes<br />

(Hypercalcemia,<br />

Hyponatremia)<br />

Seizure<br />

Trauma (subdural<br />

hematoma, epidural<br />

hematoma)<br />

Uremia<br />

Porphyria<br />

Infection (Meningitis,<br />

Encephalitis, Sepsis,<br />

specifically urosepsis<br />

in elderly)<br />

Drugs<br />

• Ranson’s Criteria:<br />

At admiss.: GALAW<br />

Glucose >200<br />

Age >55<br />

LDH >350<br />

AST>250<br />

WBC >16,000<br />

• At 48 hours-C<br />

HOBBS<br />

Calcium 10%<br />

Oxygen: PaO2 5<br />

mg/dL<br />

Base deficit >4 mEq/L<br />

Sequestration of fluid<br />

>6L<br />

• TTP (FAT RN)<br />

Fever<br />

Anemia<br />

(Microangiopathic<br />

hemolytic anemia)<br />

Thrombocytopenia<br />

Renal Failure<br />

Neuro changes (AMS)<br />

+if suspect TTP, it is<br />

an emergency to get<br />

patient to plasma<br />

exchange<br />

• Acute Dialysis<br />

Indications-AEIOU<br />

Acidemia, Electrolyte<br />

disturbances,<br />

Intoxication, Overload<br />

(volume), Uremia<br />

• Fractional<br />

excretion of Sodium<br />

(FENa)<br />

“UNaP over UCraP”<br />

(Urine Na x Plasma<br />

Cr)/(Urine Cr x<br />

Plasma Na)<br />

• Kinds Of Tumors<br />

Leaping Primarily To<br />

Bone<br />

Kidney<br />

Ovarian<br />

Thyroid<br />

Lung<br />

Prostate<br />

Testicular<br />

Breast<br />

• Drug Induced<br />

Lupus Agents-<br />

SHIPS drugs<br />

Sulfasalazine,<br />

Hydralazine,<br />

Isoniazid,<br />

Procainamide, Statins<br />

• Causes of Atrial<br />

Fibrillation<br />

I SMART CHAP<br />

Infectious<br />

(endocarditis,<br />

myocarditis, sepsis)<br />

Surgery (Post-CABG)<br />

Medications (caffeine,<br />

theophylline)<br />

Artheroclerotic CAD<br />

Rheumatic Heart<br />

Disease (MS or MR)<br />

Thyrotoxicosis<br />

Congential<br />

malformation (ASD)<br />

Hypertensive heart<br />

disease<br />

Alcohol (Alcoholic<br />

CM, Holiday Heart<br />

Syn)<br />

PE<br />

• Anion Gap<br />

Metabolic Acidosis<br />

GOLD MARK or<br />

KUSMALE<br />

Glycols<br />

Oxyproline<br />

L-lactate<br />

D-lactate<br />

Methanol<br />

Aspirin<br />

Aspirin<br />

Renal<br />

Ketoacidosis<br />

Ketones<br />

Uremia<br />

Salicylates<br />

Methanol<br />

Acetaldehyde<br />

Lactic Acidosis<br />

Ehtylene Glycol


122<br />

SUSTENANCE AND COMFORT FOOD<br />

Will deliver…<br />

www.diningin.com<br />

Bangkok City (Thai) 214-824-6200<br />

www.bangkokcityrestaurant.com<br />

You can send your students…<br />

Angry Dog (salads/sandwiches) 214-741-4406<br />

2726 Commerce, www.angrydog.com<br />

Jimmy’s Italian Deli/Food Store 214-823-6180<br />

4901 Bryan, www.jimmysfoodstore.com<br />

Lenny’s Sub Shop 214-826-1500<br />

4201 Gaston, www.lennys.com<br />

Matt’s Rancho Martinez 214-823-5517<br />

6332 La Vista, www.thetexmexchef.com<br />

Pei Wei (Asian diner) 214-219-0000<br />

3001 Knox St, www.peiwei.com<br />

Fadi’s (Mediterranean) 214-528-1800<br />

3001 Know St, www.fadiscuisine.com<br />

Chuy’s (Mexican) 214-559-2489<br />

4544 McKinney Ave, www.chuys.com<br />

Pot Belly (sandwiches)<br />

www.potbelly.com<br />

5715 Lemmon 214-353-0581<br />

4447 N Central Expressway 214-520-3251<br />

Or you can eat at <strong>BUMC</strong>…<br />

Cafeteria (Truett basement)<br />

Daily 6:30 AM-7:30 PM<br />

Bake Shop/Starbucks (next to cafeteria)<br />

M-F 6:30 AM – 2 PM<br />

Atrium (Roberts lobby)<br />

M-F 6:30 AM–1:30 AM, S/S 7:30 PM-1:30 AM<br />

Frulatti (Barnett lobby)<br />

M-F 6 AM-8 PM, Sat 8 AM-4 PM


123

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