Extending the Reach of Cardiovascular ... - pharma group

Does your blood management program fully optimize cell salvage?Perioperative autotransfusion begins with the first incision and ends when the wound drains are removed. Tominimize the likelihood of unnecessary allogeneic transfusions, optimal blood management programs needto collect, wash, and reinfuse a patient’s blood in the operating room and cardiac care unit. Only Haemoneticsdesigns cardiovascular autotransfusion systems for the intra- and postoperative care settings to help ensure allsalvageable blood is returned to the patient.OperatingRoomPatient Transfers to Cardiac Care UnitCardiacCare UnitCell Saver Systemcollects, washes,and reinfuses bloodintraoperativelycardioPAT Systemcollects, washes,and reinfuses bloodpostoperativelyThe Cell Saver® and cardioPAT® systems help you avoid unnecessaryallogeneic transfusions and return fresh, high-quality blood throughoutthe perioperative care continuum in cardiovascular surgery

cardioPAT: Avoiding unnecessary allogeneic transfusions after surgeryEvidence suggests that the majority of blood lossresulting from cardiovascular surgeries occursafter surgery. 7,8 It’s not surprising then that mostcardiovascular-related transfusions take placepostoperatively. But the risk of TRIM, infection, lengthof stay, and mortality also increase with each unitof allogeneic blood transfused. 2,5 In fact, one studyshows that allogeneic transfusion is associated with a70% increase in mortality in CABG patients. 9The appropriate standard of careInfection Rate %Figure 1. The more allogeneic blood, the greater risk of infectionDose-Response for Transfusion and Infectionin Cardiac Surgery1816141210864201 2 3 4Allogeneic Units TransfusedSevere InfectionMediastinitisPneumoniaSepsisn=738Leal-Noval et al. Chest 2001;119:1461In addition to providing chest drainage, the cardioPAT® Cardiovascular Perioperative Autotransfusion Systemcollects, washes, and returns patients’ blood after surgery, giving them the best chance at avoiding unnecessaryallogeneic transfusions and relatedrisks of infection. By consistentlydelivering fresh RBCs withhematocrit between 70–80%, youalso ensure patients receive theirown high-quality blood with zeroSeparation technologyReservoirThe Technologies That Make the cardioPAT System the Preferred ChoicePartial collection and returnDynamic Disk® consistently delivers 70–80%hematocritQuickConnect reservoir supports “collect first”approachProcesses up to 2 liters per hour and as little as5 milliliters of RBCschance of immunosuppression.Safety alertsLCD display provides operational and safety alertsThe cardioPAT QuickConnectSuctionOnboard suction with SmartSuction Harmony SystemReservoir supports a cost-effective,“collect first” approach by allowingRBC bags with integrated microaggregatefilterOptional 40-micron RBC filter bag eliminatesinconvenience of docking stand-alone filteryou to simply recover shed bloodwhen you’re not sure how muchBatteryRechargeable battery facilitates blood collection anddata storage during patient transportthe patient will bleed. With the abilityto attach to the processing set at any time, the QuickConnect Reservoir becomes your safety net, so you return thehighest quality blood only to the patients who need it, and collect blood cost-effectively for those who don’t.7Dalrymple-Hay et al. Cardiovasc Surg. 2001 Apr;9(2):184-78Murphy et al. Ann Thorac Surg. 2004 May;77(5):1553-99Engoren et al. Chest 2002;122:1309-15

The core of every quality blood management programOptimal blood management programs leverage a variety of tests, medications, and techniques to avoidunnecessary allogeneic transfusions. Intraoperative and postoperative autotransfusion must be at the core ofthese interventions and every quality blood management program because it ensures patients receive the highestquality blood possible—their own.Allogeneic blood versus perioperative autotransfusionAllogeneicBlood TransfusionIntraoperativeCell Saver®5+ SystemPostoperativecardioPAT® SystemAvoidance of unnecessary allogeneictransfusionNo Yes YesTypes of procedures usedIntra- and postoperativecardiovascular surgeryCardiovascular surgeriesand other high blood lossproceduresCardiovascular postop:CCU, ICUHematocrit50–60% 50–60% 70–80%Red blood cell recoveryN/A 95.8% 1 76.5–92.2% 1AlbuminPresent 97.3% removal 1 97.1–99.9% removal 1Free hemoglobinPresent 95.7–99.8% removal 1 93.4–99.5% removal 1HeparinN/A 97.8% removal 1 96.8–100% removal 1Increase risk of severe infection in cardiacsurgeryInfection rate 21 unit – >3%2 units – 4%3 units – 6%4 units – 16%Eliminates risk of infection and complicationsassociated with allogeneic bloodCost$1,400 per unitfully burdened 3Potential cost savings by eliminatingunnecessary allogeneic transfusions and theassociated risks of infection and immunosuppression1Data on file at Haemonetics Corporation2Leal-Noval et al. Chest 2001;119:1461-14683Shander A et al. Best Practice & Research Clinical Anesthesiology 21: pp 271-289, 2007