NCI CCC® - UW Health

a d v a n c i n g W i s c o n s i n ’ s c a n c e r r e s e a r c h a g e n d aThe UWCCC has consistentlyscheduled for a 2005 ground-Comprehensive Cancer CenterIn conjunction, the UWCCC willConsortium members will designbeen a leader in advancing thebreaking (please see pages 10-11).at the University of Wisconsin-establish a formal “Aging andand implement numerous studiesnation’s cancer research agenda.In 2002-2003, UWCCC membersreceived close to $100 million tosupport their research effortsfrom federal agencies and privatesponsors. During the past year,several exciting announcementsunderscored our level ofexcellence.$7 million federalgrant announcedTommy Thompson, Secretaryof Health and Human Servicespresented a $7 million federalgrant in September 2003 forconstruction of new UWCCCspace. The grant (of which$4 million is from the NationalCenter for Cancer Resources and$3 million from the NationalCancer Institute) will be appliedtoward a new cancer tower forHealthStar’s InterdisciplinaryResearch Complex (IRC), which isSpecifically this grant will providefunding to house interdisciplinaryprostate cancer research on oneof four new Cancer Center floorsplanned for the IRC.The announcement of this grant isthe first step toward naming theUWCCC after Paul P. Carbone,MD. Carbone, who died inFebruary 2002, served as UWCCCdirector from 1978-1997. Hisunwavering dedication to patientsand research is the foundationfor the visionary legacy weproudly pursue.The University of WisconsinFoundation and the Paul P.Carbone, MD MemorialFoundation plan to raise anadditional $10 million in privatephilanthropy to rename theUWCCC as the Paul P. CarboneMadison.Aging and CancerProgram formedWith cancer death rates far greaterfor those 65 or older, the UWCCChas been selected by the NationalInstitutes of Health as one of eightcenters to study the relationshipbetween cancer and aging.The UWCCC will receive a$3 million grant for five years ofstudy jointly funded by theNational Cancer Institute andNational Institute on Aging.“Our group at the UW is very wellpoised to investigate the relationshipbetween cancer and aging,”said Richard Weindruch, PhD, thegrant’s principal investigator.“Our efforts will span a broadarray of research ranging from thepopulation to the molecular levels.”Cancer Program” to be directedby Weindruch. “Aging andCancer” will become the ninthUWCCC research program,complementing eight existingresearch programs designed tocatalyze research with the goal ofapplying discovery to yield moreeffective patient care.UWCCC will leadchemopreventionclinical trialsNCI announced the UWCCCwill receive a $5 million contractto form a consortium led byHoward Bailey, MD to conductmultiple Phase I and II clinicaltrials of cancer chemopreventiveagents. The consortium will becomposed of five core institutions:the University of Wisconsin, theUniversity of Iowa, VanderbiltUniversity, Emory University/Gradyand the University of Rochester.on agents that may play a role inpreventing cancer.O’Brien UrologyResearch Center fundedA National Institutes of Healthgrant for more than $4 millionover five years was awarded tothe UW to fund a George M.O’Brien Urology Research Center.Wade Bushman, MD, PhD is theprincipal investigator of the grantentitled “Mechanisms forAcquired Changes in ProstateGrowth Regulation.” The grant’sunifying hypothesis is that agingand the environment produceacquired changes in prostategrowth control that predispose toneoplasia. Several physicianscientistsinvolved in prostatecancer research and treatment willcollaborate on this project.AR 2002-03 • PAGE 3