to Adjusted Operating Income (Loss) - Alere

Reconciliation of GAAP Operating Income (Loss) to Adjusted Operating Income (Loss)(in thousands)For the Three Months Ended June 30, 2012Operating SegmentProfessionalDiagnosticsHealthManagementConsumerDiagnostics Corporate TotalRevenue (GAAP) $ 540,109 $ 138,590 $ 21,818 $ - $ 700,517Adjustment related to acquired software license contracts (1) 1,126 - - - 1,126Adjusted revenue $ 541,235 $ 138,590 $ 21,818 $ - $ 701,643Operating income (loss) - (GAAP) $ 63,251 $ (12,666) $ 2,699 $ (18,930) $ 34,354Adjustment related to acquired software license contracts (1) 1,126 - - - 1,126Amortization 66,428 14,312 631 - 81,371Restructuring 817 539 - 9 1,365Stock-based compensation - - - 4,368 4,368Acquisition-related costs - - - 3,800 3,800Contingent consideration adjustments (6,901) 863 (288) (355) (6,681)Adjusted operating income (loss) $ 124,721 $ 3,048 $ 3,042 $ (11,108) $ 119,703Adjusted operating income (loss) as % of revenue 23.0% 2.2% 13.9% 17.1%(1) Estimated revenue related to acquired software license contracts that was not recognized during the second quarter of 2012 due to business combination accounting rulesReconciliation of GAAP Operating Income (Loss) to Adjusted Operating Income (Loss)(in thousands)For the Three Months Ended June 30, 2011Operating SegmentProfessionalDiagnosticsHealthManagementConsumerDiagnostics Corporate TotalRevenue $ 409,074 $ 135,572 $ 22,539 $ - $ 567,185Operating income (loss) - (GAAP) $ 49,304 $ (15,154) $ 1,902 $ (19,898) $ 16,154Amortization 61,768 18,341 860 - 80,969Restructuring 2,880 6,368 - 1,050 10,298Stock-based compensation - - - 6,181 6,181Acquisition-related costs 6 (62) - 1,472 1,416Contingent consideration adjustments (6,972) - 228 (480) (7,224)Other (1) - - - 10 10Adjusted operating income (loss) $ 106,986 $ 9,493 $ 2,990 $ (11,665) $ 107,804Adjusted operating income as % of revenue 26.2% 7.0% 13.3% 19.0%(1) Includes expenses incurred in connection with the sale of our vitamins and nutritional supplements business.Comments:In calculating "adjusted operating income (loss)" in the schedule presented above, the Company excludes from operating income (loss) (i) certain non-cash charges,including amortization expense and stock-based compensation expense, (ii) non-recurring charges and income, and (iii) certain other charges and income that have asignificant positive or negative impact on results yet do not occur on a consistent or regular basis in its business. In determining whether a particular item meets one ofthese criteria, management considers facts and circumstances that it believes are relevant. Management believes that excluding such charges and income from operatingincome (loss) allows investors and management to evaluate and compare the Company's operating results from continuing operations from period to period in ameaningful and consistent manner. Due to the frequency of their occurrence in its business, the Company does not adjust operating income (loss) for the costs associatedwith litigation, including payments made or received through settlements. It should be noted that "adjusted operating income (loss)" is not a standard financialmeasurement under accounting principles generally accepted in the United States of America ("GAAP") and should not be considered as an alternative to operatingincome (loss) as an indicator of operating performance or any measure of performance derived in accordance with GAAP. In addition, all companies do not calculate non-GAAP financial measures in the same manner and, accordingly, "adjusted operating income (loss)" presented in this schedule may not be comparable to similar measuresused by other companies.Reference should also be made to the Company's financial results contained in our earnings press release respective to the periods presented in this schedule, whichinclude a more detailed discussion of the adjustments to the GAAP operating results presented above.

Reconciliation of GAAP Operating Income (Loss) to Adjusted Operating Income (Loss)(in thousands)For the Six Months Ended June 30, 2012Operating SegmentProfessionalDiagnosticsHealthManagementConsumerDiagnostics Corporate TotalRevenue (GAAP) $ 1,058,466 $ 269,374 $ 43,806 $ - $ 1,371,646Adjustment related to acquired software license contracts (1) 2,412 - - - 2,412Adjusted revenue $ 1,060,878 $ 269,374 $ 43,806 $ - $ 1,374,058Operating income (loss) - (GAAP) $ 133,430 $ (32,022) $ 3,064 $ (35,060) $ 69,412Adjustment related to acquired software license contracts (1) 2,412 - - - 2,412Amortization 129,313 28,636 1,351 - 159,300Restructuring 5,611 1,256 - 26 6,893Stock-based compensation - - - 8,242 8,242Non-cash charge associated with acquired inventory 4,681 - - - 4,681Acquisition-related costs - - - 5,261 5,261Contingent consideration adjustments (6,325) 3,167 (204) 1,725 (1,637)Adjusted operating income (loss) $ 269,122 $ 1,037 $ 4,211 $ (19,806) $ 254,564Adjusted operating income (loss) as % of revenue 25.4% 0.4% 9.6% 18.5%(1) Estimated revenue related to acquired software license contracts that was not recognized during the second quarter of 2012 due to business combination accounting rulesReconciliation of GAAP Operating Income (Loss) to Adjusted Operating Income (Loss)(in thousands)For the Six Months Ended June 30, 2011Operating SegmentProfessionalDiagnosticsHealthManagementConsumerDiagnostics Corporate TotalRevenue $ 824,886 $ 278,635 $ 46,128 $ - $ 1,149,649Operating income (loss) - (GAAP) $ 109,566 $ (27,087) $ 5,263 $ (40,683) $ 47,059Amortization 117,129 38,228 1,729 - 157,086Restructuring 4,858 10,589 - 1,050 16,497Stock-based compensation - - - 11,989 11,989Acquisition-related costs 6 74 - 3,199 3,279Contingent consideration adjustments (6,883) - (225) 1,269 (5,839)Other (1) - - - 23 23Adjusted operating income (loss) $ 224,676 $ 21,804 $ 6,767 $ (23,153) $ 230,094Adjusted operating income as % of revenue 27.2% 7.8% 14.7% 20.0%(1) Includes expenses incurred in connection with the sale of our vitamins and nutritional supplements business.Comments:In calculating "adjusted operating income (loss)" in the schedule presented above, the Company excludes from operating income (loss) (i) certain non-cash charges,including amortization expense and stock-based compensation expense, (ii) non-recurring charges and income, and (iii) certain other charges and income that have asignificant positive or negative impact on results yet do not occur on a consistent or regular basis in its business. In determining whether a particular item meets one ofthese criteria, management considers facts and circumstances that it believes are relevant. Management believes that excluding such charges and income from operatingincome (loss) allows investors and management to evaluate and compare the Company's operating results from continuing operations from period to period in ameaningful and consistent manner. Due to the frequency of their occurrence in its business, the Company does not adjust operating income (loss) for the costs associatedwith litigation, including payments made or received through settlements. It should be noted that "adjusted operating income (loss)" is not a standard financialmeasurement under accounting principles generally accepted in the United States of America ("GAAP") and should not be considered as an alternative to operatingincome (loss) as an indicator of operating performance or any measure of performance derived in accordance with GAAP. In addition, all companies do not calculate non-GAAP financial measures in the same manner and, accordingly, "adjusted operating income (loss)" presented in this schedule may not be comparable to similar measuresused by other companies.Reference should also be made to the Company's financial results contained in our earnings press release respective to the periods presented in this schedule, whichinclude a more detailed discussion of the adjustments to the GAAP operating results presented above.