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Exploring Bioethics - NIH Office of Science Education - National ...

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In Advance1Preparing the Envelopes for Day 1, Activity 1For Day 1, each student will need a sealed envelope labeled “MedicalRecords: Alzheimer’s Test Result.” Inside each envelope should be a slip <strong>of</strong>paper with his or her hypothetical test result—telling the student which two<strong>of</strong> the alleles linked to Alzheimer’s disease (E2, E3, and E4) he or she has. Toapproximate the human population as a whole, prepare the envelopes in thefollowing ratio (numbers can be modified according to the total number <strong>of</strong>students; numbers below add to up 50 total envelopes):2Number <strong>of</strong> envelopes What the slip <strong>of</strong> paper should say1 E2/E27 E2/E328 E3/E31 E2/E412 E3/E41 E4/E4Source: Based on data from Hill, J.M., Bhattacharjee, P.S., and Neumann, D.M. 2007. ApolipoproteinE alleles can contribute to the pathogenesis <strong>of</strong> numerous clinical conditions including HSV-1 cornealdisease. Experimental Eye Research, 84: 801–11.3Copies, Equipment, and MaterialsActivity123456Module 4Photocopies and TransparenciesDay 1• 1 transparency each <strong>of</strong> Masters 4.1 (optional) and 4.2for the class• 1 copy <strong>of</strong> Master 4.2 for each student• 1 sealed envelope (marked “Medical Records: Alzheimer’sTest Result”) for each studentEquipment and Materials1 overhead projector, 1 sheet posterpaper, 1 marker for teacher use1 transparency <strong>of</strong> Master 4.3 for the class 1 overhead projector, 1 sheet posterpaper, 1 marker for teacher use• 1 transparency <strong>of</strong> Master 4.4 for the class• 1 copy each <strong>of</strong> Masters 4.4, 4.5, and 4.6 for each student1 overhead projector, 1 sheet posterpaper, 1 marker for teacher useDay 21 transparency <strong>of</strong> Master 4.6 (optional) for the class 1 overhead projector (optional) forteacher use• 1 transparency each <strong>of</strong> Masters 4.3 and 4.7 for the class• 1 copy each <strong>of</strong> Masters 4.3 and 4.7 for each student• 1 transparency <strong>of</strong> Master 4.8 for the class• 1 copy each <strong>of</strong> Masters 4.8 and 4.9 for each student4-51 overhead projector for teacher use1 overhead projector for teacher useContinued456

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