Zaroxolyn (metolazone) - Sanofi Canada
Zaroxolyn (metolazone) - Sanofi Canada
Zaroxolyn (metolazone) - Sanofi Canada
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PHARMACEUTICAL INFORMATIONCHEMISTRYTrade Name:Proper Name:ZAROXOLYN<strong>metolazone</strong>Chemical name: 7-chloro-1,2,3,4-tetrahydro-2-methyl-3- 2-methylphenyl)-4-oxo-6-quinazolinesulfonamideStructural Formula:Molecular Formula: C 16 H 16 ClN 3 O 3 SMolecular Weight: 365.83Description:Solubility:white crystalline powderin water (gm/mL): 2.4 x 10 -5 , 25ECin 95% ethanol (gm/mL): 9 x 10 -3 ,25ECin serum (gm/mL): 4.2 x 10 -5 , 37ECpKa: 9.7Melting Point:Composition:253 - 259ECZAROXOLYN 2.5 mg tablets contain 2.5 mg of the active ingredient<strong>metolazone</strong>.Stability and Storage Recommendations:ZAROXOLYN (<strong>metolazone</strong>) should be stored at room temperature and protected from light.ZAROXOLYN should be dispensed in tight, light-resistant containers.9