Syllabus - The Swami Ramanand Teerth Marathwada University
Syllabus - The Swami Ramanand Teerth Marathwada University
Syllabus - The Swami Ramanand Teerth Marathwada University
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<strong>Swami</strong> <strong>Ramanand</strong> <strong>Teerth</strong> <strong>Marathwada</strong> <strong>University</strong>, Nanded<br />
School of Technology<br />
M.Pharm. <strong>Syllabus</strong> (Credit System)<br />
Effective from September 2008<br />
M. Pharm. (Semester – II)<br />
Pharmaceutical Chemistry<br />
Subject code : MPY - 221<br />
Subject : ADVANCED ORGANIC CHEMISTRY<br />
THEORY 60 Hours (4 hrs. /week)<br />
1. STEREOCHEMISTRY 12 hrs<br />
Molecular dissymmetry, compounds with one, two or more unequal asymmetric<br />
carbon atoms and recimic modifications, configuration absolute and relative,<br />
synthesis of optically active compounds, conformations in cyclic compounds, optical<br />
isomerism, shapes of cyclohexanes and six-membered heterocyclic rings, shapes of<br />
rings other than six membered. Stereoselective synthesis, role of inductive, resonance<br />
and steric effects in structure and relativity.<br />
2. MECHANISM STEREOCHEMISTRY AND APPLICATIONS OF 12 hrs<br />
Birch reduction, Clemensen reduction, Meerwein-Pondroff reduction, Oppennauer<br />
oxidation, Wolf Kishner reduction, Witting Reaction, Pinacol and related<br />
rearrangements, Beckmann rearrangement, Hoffman rearrangement, Claisen<br />
rearrangement, Schmidt, Lossen and Curtius rearrangement.<br />
3. PERICYCLIC REACTIONS 8 hrs<br />
Basic theory, orbital symmetry rules and their applications, mechanism, types of<br />
pericyclic reactions-cycloaddition, electrolytic reaction, and sigmatrophic<br />
rearrangement<br />
4. PHOTOCHEMICAL REACTIONS 7 hrs<br />
Introductions and basic principles, photochemistry of carbonyl compounds, photo<br />
rearrangements, photochemistry of alkenes and dienes.