Mechanisms of aluminium neurotoxicity in oxidative stress-induced ...
Mechanisms of aluminium neurotoxicity in oxidative stress-induced ... Mechanisms of aluminium neurotoxicity in oxidative stress-induced ...
List of figures (continuation) Chapter 3 Figure 1 Levels of TBARS, protein carbonyls, and protein thiols in different brain areas of rats i.p. treated with saline or aluminium chloride for ten days Figure 2 Enzyme activity of SOD, GPx, and CAT in different brain areas of rats i.p. treated with saline or aluminium chloride for ten days Figure 3 Microphotographs showing changes in the striatal TH-ir one week post-lesion in rats injected intraventricularly Figure 4 Density of striatal DAergic terminals estimated as optical density, one week post-surgery in the different experimental groups. Figure 5 Levels of TBARS, protein carbonyls, and protein thiols in both ventral midbrain and striatum of different groups of rats Figure 6 In vitro effects of aluminium on TBARS formation, protein carbonyl content, and protein thiol content induced by the autoxidation of 6-OHDA in mitochondrial preparations from rat brain 138-139 140-141 142 143 144-145 146-147
List of tables Introduction Table 1 Differential diagnostic in parkinsonian disorders 9 Table 2 UK Parkinson’s Disease Society Brain Bank’s diagnostic criteria for the diagnosis of probable PD 10 Table 3 National Institute of Neurological Disorders (NINDS) diagnostic criteria for PD 11 Table 4 Gene loci associated with PD 26 Table 5 Lipid composition of normal adult human brain 65 Chapter 2 Table 1 Graphite furnace programme for aluminium determination by ETAAS Chapter 3 Table 1 In vitro effects of the presence of aluminium on the enzyme activities of SOD, GPx, CAT, and MAO 113 137
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- Page 11 and 12: Abbreviations AA ascorbic acid AD A
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- Page 21: CHAPTER 3 Brain oxidative stress an
- Page 25 and 26: INTRODUCTION PARKINSON’S DISEASE
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- Page 35 and 36: INTRODUCTION Table 3: National Inst
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List <strong>of</strong> figures (cont<strong>in</strong>uation)<br />
Chapter 3<br />
Figure 1 Levels <strong>of</strong> TBARS, prote<strong>in</strong> carbonyls, and prote<strong>in</strong> thiols <strong>in</strong> different<br />
bra<strong>in</strong> areas <strong>of</strong> rats i.p. treated with sal<strong>in</strong>e or <strong>alum<strong>in</strong>ium</strong> chloride<br />
for ten days<br />
Figure 2 Enzyme activity <strong>of</strong> SOD, GPx, and CAT <strong>in</strong> different bra<strong>in</strong> areas <strong>of</strong><br />
rats i.p. treated with sal<strong>in</strong>e or <strong>alum<strong>in</strong>ium</strong> chloride for ten days<br />
Figure 3 Microphotographs show<strong>in</strong>g changes <strong>in</strong> the striatal TH-ir one week<br />
post-lesion <strong>in</strong> rats <strong>in</strong>jected <strong>in</strong>traventricularly<br />
Figure 4 Density <strong>of</strong> striatal DAergic term<strong>in</strong>als estimated as optical density,<br />
one week post-surgery <strong>in</strong> the different experimental groups.<br />
Figure 5 Levels <strong>of</strong> TBARS, prote<strong>in</strong> carbonyls, and prote<strong>in</strong> thiols <strong>in</strong> both<br />
ventral midbra<strong>in</strong> and striatum <strong>of</strong> different groups <strong>of</strong> rats<br />
Figure 6 In vitro effects <strong>of</strong> <strong>alum<strong>in</strong>ium</strong> on TBARS formation, prote<strong>in</strong><br />
carbonyl content, and prote<strong>in</strong> thiol content <strong>in</strong>duced by the<br />
autoxidation <strong>of</strong> 6-OHDA <strong>in</strong> mitochondrial preparations from rat<br />
bra<strong>in</strong><br />
138-139<br />
140-141<br />
142<br />
143<br />
144-145<br />
146-147