Mechanisms of aluminium neurotoxicity in oxidative stress-induced ...
Mechanisms of aluminium neurotoxicity in oxidative stress-induced ... Mechanisms of aluminium neurotoxicity in oxidative stress-induced ...
CHAPTER 2 Analysis of brain regional distribution of aluminium in rats via oral and intraperitoneal administration Sofía Sánchez-Iglesias,* Ramón Soto-Otero,* Javier Iglesias-González,* M. Carmen Barciela-Alonso,† Pilar Bermejo-Barrera† and Estefanía Méndez-Álvarez* *Laboratory of Neurochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain †Department of Analytical Chemistry, Nutrition and Bromatology, Faculty of Chemistry, University of Santiago de Compostela, Santiago de Compostela, Spain J. Trace Elem. Med. Biol. (2007) 21, S1, 31–34. 103
- Page 75 and 76: INTRODUCTION induce selective DAerg
- Page 77 and 78: ALUMINIUM General features INTRODUC
- Page 79 and 80: INTRODUCTION Varying amounts of alu
- Page 81 and 82: INTRODUCTION and antiperspirants co
- Page 83 and 84: INTRODUCTION approximately 3% of al
- Page 85 and 86: Excretion INTRODUCTION As insoluble
- Page 87 and 88: INTRODUCTION 3.5 mg may be increase
- Page 89 and 90: INTRODUCTION Oteiza 1999), non-iron
- Page 91 and 92: Aluminium as a cell membrane menace
- Page 93 and 94: INTRODUCTION mobilization of Ca 2+
- Page 95: Aluminium impairs neurotransmission
- Page 99 and 100: AIMS OF THE PRESENT THESIS The main
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- Page 104 and 105: OBJETIVOS 3) Evaluar de forma preci
- Page 107: CHAPTER 1 Time-course of brain oxid
- Page 110 and 111: CHAPTER 1 INTRODUCTION 86 6-OHDA (2
- Page 112 and 113: CHAPTER 1 MATERIALS AND METHODS Che
- Page 114 and 115: CHAPTER 1 followed by centrifugatio
- Page 116 and 117: CHAPTER 1 RESULTS Effects of 6-OHDA
- Page 118 and 119: CHAPTER 1 DISCUSSION 94 As shown by
- Page 120 and 121: CHAPTER 1 strategies or to study th
- Page 122 and 123: CHAPTER 1 Fig. 2 Changes in PCC in
- Page 125: CHAPTER 2
- Page 130 and 131: CHAPTER 2 INTRODUCTION 106 Aluminiu
- Page 132 and 133: CHAPTER 2 experimental period of fo
- Page 134 and 135: CHAPTER 2 RESULTS Aluminium distrib
- Page 136 and 137: CHAPTER 2 significant increase of t
- Page 139: CHAPTER 3
- Page 143 and 144: ABSTRACT CHAPTER 3 The ability of a
- Page 145 and 146: CHAPTER 3 not undergo redox reactio
- Page 147 and 148: CHAPTER 3 saline over the same peri
- Page 149 and 150: CHAPTER 3 used as chemical dosimete
- Page 151 and 152: Statistical analysis CHAPTER 3 Data
- Page 153 and 154: CHAPTER 3 was noted in hippocampus
- Page 155 and 156: CHAPTER 3 In vitro effects of alumi
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- Page 161 and 162: CHAPTER 3 Table 1. In vitro effects
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- Page 167 and 168: CHAPTER 3 Fig. 4 Density of striata
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- Page 175 and 176: SUMMARY SUMMARY Aluminium has becom
CHAPTER 2 Analysis <strong>of</strong> bra<strong>in</strong> regional distribution <strong>of</strong><br />
<strong>alum<strong>in</strong>ium</strong> <strong>in</strong> rats via oral and <strong>in</strong>traperitoneal adm<strong>in</strong>istration<br />
S<strong>of</strong>ía Sánchez-Iglesias,* Ramón Soto-Otero,* Javier Iglesias-González,*<br />
M. Carmen Barciela-Alonso,† Pilar Bermejo-Barrera† and Estefanía<br />
Méndez-Álvarez*<br />
*Laboratory <strong>of</strong> Neurochemistry, Department <strong>of</strong> Biochemistry and Molecular Biology, Faculty <strong>of</strong> Medic<strong>in</strong>e,<br />
University <strong>of</strong> Santiago de Compostela, Santiago de Compostela, Spa<strong>in</strong><br />
†Department <strong>of</strong> Analytical Chemistry, Nutrition and Bromatology, Faculty <strong>of</strong> Chemistry, University <strong>of</strong><br />
Santiago de Compostela, Santiago de Compostela, Spa<strong>in</strong><br />
J. Trace Elem. Med. Biol. (2007) 21, S1, 31–34.<br />
103
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