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What Works for Women and Girls

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vention immediately following the baseline survey, while six comparison communitiesreceived the intervention after the follow-up survey two years later. HIV incidence wasconsistently lower in the intervention community than the comparison community inall six matched pairs. After two years of the intervention, there were 48 seroconversions(1.2%) in the intervention group <strong>and</strong> 82 (1.9%) in the comparison group. HIV incidencewas approximately 42% lower in the intervention group. Prevalence <strong>and</strong> incidence ofSTIs was measured in a r<strong>and</strong>om cohort consisting of 1,000 adults in each community.STI services were based on syndromic algorithms recommended by WHO (WHO,1991). The intervention program had five components: 1) Establishment of an STIreference clinic <strong>and</strong> laboratory to monitor the effectiveness of treatment algorithms;2) Existing staff from health centers received one week of classroom training <strong>and</strong> twoweeks of practical training at the STI clinic. Staff also were trained to provide patientswith health education <strong>and</strong> to offer free condoms; 3) A special delivery system of drugswas established to supplement the national essential drugs program supplies; 4) Regularsupervisory visits by a program officer were conducted to provide in-service training<strong>and</strong> to check drug supplies <strong>and</strong> patient records; 5) Periodic visits by health educators tovillagers were conducted to provide in<strong>for</strong>mation on STIs, in<strong>for</strong>m villagers of availabletreatment, <strong>and</strong> encourage prompt attendance <strong>for</strong> treatment of symptomatic STIs. Menwith a positive LED test <strong>and</strong> those reporting or found to have urethral discharge wereasked to provide a urethral swab. Urethral swabs were tested <strong>for</strong> Neisseria gonorrheaby pram stain <strong>and</strong> <strong>for</strong> Chlamydia trachoatis by antigen capture immunoassay. HIV wastested by ELISA assay. Positive samples received a second ELISA assay, <strong>and</strong> in caseof discrepant or indeterminate ELISA results, a western blot test. Serological tests <strong>for</strong>syphilis were conducted using RPR <strong>and</strong> TPHA. Evaluation of the impact of the interventionon the prevalence of STIs was based on the seroprevalence of active syphilis <strong>and</strong>on the prevalence of confirmed urethritis, N gonorrhea <strong>and</strong> C traehomanis infectionin men. Surveys indicated that condom use did not increase nor did sexual behaviorchange during the course of the intervention (Grosskurth et al., 1995). (Gray III) (STIs,health facilities, treatment, Tanzania)3. Providing VCT together with STI services can reach women at high risk <strong>for</strong> HIV. [SeeChapter 6. HIV Testing <strong>and</strong> Counseling <strong>for</strong> <strong>Women</strong>]Gaps in Programming—Treating Sexually Transmitted Infections1. Interventions are needed to screen <strong>and</strong> treat both male <strong>and</strong> female sexual partners <strong>for</strong> STIs.2. While treatment of all STIs can improve everyone’s health <strong>and</strong> well-being, ulcerative STIshave the most impact on HIV susceptibility <strong>and</strong> transmission. However, to date, regimens tosuppress genital herpes have not been effective in reducing HSV transmission.WHAT WORKS FOR WOMEN AND GIRLS73

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