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What Works for Women and Girls

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<strong>What</strong> <strong>Works</strong>—Prevention <strong>for</strong> <strong>Women</strong>: Treating Sexually Transmitted Infections1. STI counseling, diagnosis <strong>and</strong> treatment represent an important access point <strong>for</strong> women athigh risk of HIV, particularly in the earlier stages of the epidemic.Promising Strategies:2. Screening <strong>for</strong> <strong>and</strong> treating STIs on a continuous, accessible basis improves overall healthsystems, <strong>and</strong> has been associated with reducing the risks of HIV acquisition in a setting withhigh STI prevalence.3. Providing VCT together with STI services can reach women at high risk <strong>for</strong> HIV.EVIDENCE1. STI counseling, diagnosis <strong>and</strong> treatment represent an important access point <strong>for</strong> womenat high risk of HIV. [See also Chapter 9C-1. Safe Motherhood <strong>and</strong> Prevention of VerticalTransmission: Testing <strong>and</strong> Counseling]A systematic review <strong>and</strong> meta-analysis of 1,064 reports between 1998 <strong>and</strong> 2000 foundthat genital ulcerative disease appears to have a greater impact than nonulcerativedisease on the susceptibility to HIV. Men were more affected than women by the effectsof STIs Untreated concurrent STIs in an HIV-positive individual increases the rateof progression towards AIDS. “A better <strong>and</strong> more quantitative underst<strong>and</strong>ing of theinteractions between HIV infection <strong>and</strong> classic STDs is needed ...Sexual behavior is thecommon risk factor <strong>for</strong> contracting both HIV <strong>and</strong> STDs” (Rottingen et al., 2001: 592).(Gray I) (STIs, genital ulcers)A review of 2,101 articles in Medline <strong>and</strong> International Conferences on AIDS foundthat both ulcerative <strong>and</strong> non-ulcerative STIs promote HIV transmission. Risk estimatesfound in prospective studies from four continents ranged from two to over 23. “Owingto the greater frequency of non-ulcerative STIs in many populations, these infectionsmay be more responsible <strong>for</strong> more HIV transmission than genital ulcers” (Fleming <strong>and</strong>Wasserheit, 1999: 3). (Gray I) (STIs, genital ulcers)A 2004 to 2006 cross-sectional survey study of female sex workers in India found thatof the 976 women who had symptoms of an STI, more than 78% sought medical treatment;behavior that was protective <strong>for</strong> both HIV <strong>and</strong> STIs. HIV infection was stronglyassociated with lifetime <strong>and</strong> active syphilis (Mishra et al., 2009). (Gray III) (STIs, syphilis,India)In a study where 109,500 samples were tested during a nine-month period frompatients in STI clinics in the US, Malawi <strong>and</strong> South Africa, 1 to 2 percent had acute HIVWHAT WORKS FOR WOMEN AND GIRLS71

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