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What Works for Women and Girls

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Training a key obstetrician on antiretroviral treatment at a medical center in Tanzaniaresulted in 25 women needing HAART gaining timely access to treatment (Ginsburg etal., 2007). (Gray V) (providers, training programs, HAART, Tanzania)In a study at Coronation <strong>Women</strong> <strong>and</strong> Children Hospital, South Africa, data were gatheredfrom HIV-positive women attending antenatal care from June 2004 to July 2005 toevaluate linking antenatal with antiretroviral treatment (ARV) services. After a patientrecord review, interventions were implemented to strengthen service linkages <strong>and</strong> integrateARV treatment within antenatal care. Laboratory investigations were streamlined,including CD4 cell count testing at the first antenatal visit. MTCT risk <strong>for</strong> women initiatingARV treatment was compared with that of women-infant pairs receiving singledosenevirapine (sd-NVP). In total, 164 pregnant women initiated ARV treatment <strong>and</strong>863 received sd-NVP. After changes to service delivery, time-to-treatment initiation wasreduced from a median of 56 days to 37 days. The risk of MTCT <strong>for</strong> women receivingARV treatment was lower than <strong>for</strong> those given sd-NVP (van der Merwe et al., 2006).(Gray V) (PMTCT, treatment, antenatal care, South Africa)6. PMTCT-Plus (family-focused) HIV care can increase the numbers of women <strong>and</strong> theirmale partners who access testing <strong>and</strong> treatment.A study from Côte d’Ivoire evaluating an MTCT-plus program from 2003 to 2005 founda significant increase in antiretroviral treatment initiation <strong>and</strong> high rates of retention incare <strong>for</strong> women <strong>and</strong> their partners. Of the 605 women enrolled during the study period,fewer than 2% of women <strong>and</strong> 9% of their partners were receiving antiretroviral treatmentprior to enrollment in the program, in comparison to 41.5% of women <strong>and</strong> 65%of their partners after enrollment at the close of the study period. Retention rates werealso high: only 2.5% of women <strong>and</strong> 5.5% of partners initiating ART were lost to followup,while 2% of women <strong>and</strong> 0% of partners not eligible <strong>for</strong> ART were lost to follow-up(Tonwe-Gold et al., 2009). (Gray III) (PMTCT-Plus, treatment, Côte d’Ivoire)A study in rural Ug<strong>and</strong>a providing PMTCT-Plus resulted in vertical HIV transmissionrate dropping from over 27% to 8%; a HAART adherence rate of more than 95% <strong>for</strong>80% of clients <strong>and</strong> an overall 36-month mortality rate of 8%. The program reached16,000 pregnant women, 1,454 children <strong>and</strong> 683 men with VCT <strong>and</strong> HIV services.Services consisted of patient monitoring using WHO clinical staging, generic antiretroviraldrugs <strong>and</strong> rapid HIV testing. Social services included nutrition interventions,loans <strong>and</strong> home based water chlorination. All services were incorporated into reproductivehealth services (Lukoda <strong>and</strong> Gibson, 2008). (Abstract) (PMTCT-plus, HAART,PMTCT, HIV testing, Ug<strong>and</strong>a)244 CHAPTER 9 SAFE MOTHERHOOD AND PREVENTION OF VERTICAL TRANSMISSION

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