KUTLUK OKTAY, MD, FACOG CURRICULUM VITAE M.D. DEGREE ...

KUTLUK OKTAY, MD, FACOGCURRICULUM VITAEM.D. DEGREEHacettepe University Medical School, Ankara, Turkey 9/2/1980 – 7/31/1986Department of Internal MedicineMarmara University Hospital, Istanbul 12/1/1986 – 3/15/1988ACCREDITED RESIDENCIESInternal MedicineCook County Hospital, Chicago 7/1/1988 – 6/30/1989Obstetrics & GynecologyColumbia University College of Physicians & Surgeons,Harlem Hospital Center, NY 7/1/1989 – 6/30/1991University of Connecticut Health Center 7/1/1991 – 6/30/1993ACCREDITED FELLOWSHIPSReproductive Endocrinology & InfertilityUniversity of Texas HSC at San Antonio 7/1/1993 – 6/30/1995RESEARCH FELLOWSHIPSACOG-RCOG (WellBeing) UK Research FellowshipUniversity of Leeds School of Medicine, Division of 7/15/1995 – 8/31/1996Reproductive Biology, Dept. Obstetrics & GynecologyLeeds, United KingdomBOARD EXAMS & CERTIFICATIONReproductive Endocrinology & Infertility 03/31/1999American Board of Obstetrics & Gynecology 11/07/1997ABC recertification 12/10/2007LICENSUREState of New York:State of Texas:12/17/1997 - present08/12/1993 - presentCURRENT PROFESSIONAL MEMBERSHIPSAmerican Society of Clinical OncologySociety for Assisted Reproductive Technology

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGPediatric Hematology and OncologyJ Society for Gynecologic InvestigationThe LancetNatureReproductionJ Clin Endocrinol MetabolLancet OncologyEndocrinologyReproduction, Fertility and DevelopmentHuman Reproduction UpdateHuman ReproductionBiology of ReproductionFertility & SterilityCell & Tissue ResearchObstetrics & GynecologyCOMMITTEE MEMBERSHIPSSociety for Gynecologic Investigation Scientific Program Committee 2005 - presentCo-Chair, ASCO Guideline Committee for Fertility Preservation in 2005 - presentBreast Cancer PatientsChair, American Society of Reproductive Medicine Fertility2005 - presentPreservation Abstract CommitteeMember, ESHRE Scientific Abstract Review Committee2003-presentMember, Grant Review Committee, Israel Science Foundation 2003Member, Grant Review Committee, Cancer Research UK 2003Chair, Steering Committee, Fertility Preservation Special Interest Group, 2002-2004American Society for Reproductive MedicineMember, Organizing Committee, Parenthood Beyond Cancer Conference,MD Anderson, Houston, TX 2002 - 2004University of Lyon, France, Ph.D. Thesis Review Committee 2002Brooklyn Hospital, Department of OB/GYN Curriculum Committee 2001 - 2003Brooklyn Hospital, Department of OB/GYN Research Committee 2000 – 2003Society for Gynecologic Investigation Scientific Program Committee 2000 - 2002ACADEMIC ADMINISTRATIVE APPOINTMENTSProfessor of Obstetrics & Gynecology on Tenure Track, 01/01//2008-Department of Obstetrics & GynecologyNew York Medical College, Valhalla, NYDirector, Division of Reproductive Medicine 01/01/2008-Department of Obstetrics & GynecologyNew York Medical College, Valhalla, NY3

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGUniversity of Texas HSC at San AntonioAWARDS & ACHIEVEMENTS• Faculty of 1000 2007• Listed in the Marquis Who’s Who in American Education 2007• Listed in the Marquis Who’s Who in Science and Engineering 10 th Edition 2007• “Champions of Hope” Award presented by Fertile Hope 2006• Listed among the America’s Top Obstetricians and Gynecologists 2006by Consumers’ Research Council of America• Canadian Fertility Society Best Basic Science Paper Award at the 2005Annual meeting of American Society for Reproductive Medicine• Listed in the Madison Who’s Who of Executives and Professionals 2005• Listed in the Marquis Who’s Who in Science and Engineering 9 th Edition 2005• Invited Speaker, President’s Cancer Panel 2005• Listed in the Marquis Who’s Who in American Education 7 th Edition 2005• Listed in the Marquis Who’s Who in Medicine and Healthcare 6 th Edition 2005• American Society for Reproductive Medicine General Program 2004Paper Candidate• Society for Assisted Reproductive Technology Prize Paper Candidate 2004• Listed among the “Choice Doctors” in N.Y. in Better Living Magazine 2004• Nominated for the Established Clinician Award by the EuropeanSociety of Human Reproduction and Embryology (ESHRE) 2004• Listed among the “Best Doctors” in N.Y. by New York Magazine 2004• Listed in the Marquis Who’s Who in Science and Technology 2004• Listed in the Marquis Who’s Who in Medicine and Healthcare 2004• Listed among the “Best Doctors” in N.Y. by New York Magazine 2003• Listed among the “Top Doctors” in America, Castle & Connoly 2003• Listed in the Marquis Who’s Who in Science and Technology 2003• Listed in the Marquis Who’s Who in Health Care in America 2003• American Society for Reproductive Medicine and Society for Assisted• Reproductive Technology Prize Paper Nominee 2002• Listed among the “Best Doctors” in N.Y. by New York Magazine 2002• Listed among the “Top Doctors” in America, Castle & Connoly 2002• Listed among the “Top Family Doctors” in America,Ladies’ Home Journal 2002• Listed in the Marquis Who’s Who in Health Care in America 2002• Listed among the “Top Doctors” in America, Castle & Connoly 2001• Listed among the “Best Doctors” in N.Y. by New York Magazine 2001• Resolve’s Director’s Award for Outstanding Research in 2000Reproductive Medicine, NY, NY• ASRM-First Prize Video Award, San Diego, California 2000• Ovarian Transplant Listed among the “Top 10 Science Stories” 19995

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG• ASRM-Serono Research Award 1999• ASRM-Best Video in Assisted Reproduction Technologies 1999Toronto, Canada• ASRM 2nd Prize Video award, Toronto, Canada 1999• Listed among the “Best Doctors” in N.Y. by New York Magazine 1998• Outstanding Contribution to Human Reproduction Journal 1998• ASRM - Mead Johnson Research Award 1997• ASRM 1 st Prize Video Award , Boston, MA 1996• ASRM-Society of Reproductive Endocrinologists prize paper nominee 1996Boston, MA• ACOG-RCOG (WellBeing) UK research fellowship award Leeds, UK 1995• Dr. Spero Neckles outstanding resident research award, 1993• Farmington, CT• ACOG District I Junior Fellow Meeting prize paper nominee, 1993Portland, ME• AMA Physicians' Recognition Award 1990PUBLICATIONSManuscripts:1. Azim A, Costantini-Ferrando, Oktay K. Safety of Fertility Preservation by OvarianStimulation with Letrozole and Gonadotropins in Breast cancer Patients: A prospectivecontrolled study. J Clin Oncol 2008, (in press).2. Oktay K & Cil AP. Who is the Best Candidate for Oocyte Cryopreservation Research?Fertil Steril (in press).3. Oktay K, Buyuk E, Öktem Ö, Oktay M, Giancotti F. Jun Amino Terminal KinaseRegulates G2/M Transition Through A Mechanism Upstream of Aurora-B. Cell Cycle2008 Feb 15; 7(4); 533-541 (e-pub ahead of publication).4. Reh A, Oktem O, Oktay K. Impact of breast cancer chemotherapy on ovarian reserve: aprospective observational analysis by menstrual history and ovarian reserve markers.Fertil Steril. 2007 Dec 29; [Epub ahead of print].5. Bhangoo A, Buyuk E, Oktay K, Ten S. Phenotypic Features of 46, XX Females withStAR Protein Mutations. Pediatr Endocrinol Rev. 2007 Dec;5(2):633-41.6. Oktay K, Sönmezer M. Fertility issues and options in young women with cancer. RecentResults Cancer Res. 2008;178:203-24.7. Oktay K & Meirow D. Effects of Cancer Therapy on Fertility and Reproduction.Sexuality, Reproduction and Menopause, 2007 5(1):17-21.6

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG8. Öktem Ö and Oktay K. A Novel Ovarian Xenografting Model to Characterize the Impactof Chemotherapy Agents on Human Primordial Follicle Reserve. Cancer Res. 2007 Nov 1;67(21): 10159-61.9. Öktem Ö and Oktay K. Quantitative Assessment of the Impact of Chemotherapy onOvarian Follicle Reserve and Stromal Function. Cancer. 2007 Oct 11; 110(10): 2222-2229.[Epub ahead of print].10. Oktay K, Sönmezer M, Öktem Ö, Fox K, Emons G, Bang H. Absence Of The ConclusiveEvidence For The Safety And Efficacy Of The Gonadotropin Releasing Hormone AnalogTreatment In Protecting Against Chemotherapy-Induced Gonadal Injury. Oncologist. 2007Sep; 12(9): 1056-66.11. Oktay K and Sönmezer M. Fertility Preservation in Gynecologic Cancers. Curr OpinOncol. 2007 Sep; 19(5): 506-11.12. Oktem Ö, Oktay K. The Role Of Extracellular Matrix And Activin-A In In Vitro GrowthAnd Survival Of Murine Preantral Follicles. Reprod Sci. 2007 May; 14(4): 358-66.13. Oktay K and Oktem Ö. Regeneration of Ooocytes Post-chemotherapy: Connecting theEvidence from Mouse to Human. J Clin Oncol 2007 Aug 1;25(22):3185-7.14. Oktay K, Demirtas E, Son W-Y, Lostritto K, Chian R-C, Tan S-L. In Vitro Maturation OfGerminal Vesicle Oocytes Recovered Post-Premature LH Surge: Description Of A NovelApproach To Fertility Preservation. Fertil Steril, 2007 May 19; [Epub ahead of print].15. Azim A & Oktay K. Letrozole for ovulation induction and fertility preservation by embryocryopreservation in young women with endometrial carcinoma. Fertil Steril, 2007 Aprn9;[Epub ahead of print]16. Oktay K, Azim A, Constantini-Ferando M, Lostritto K. Relative Potency of AnastrozoleVersus Letrozole to Supress Estradiol in Breast Cancer Patients Undergoing OvarianStimulation Before IVF, J Clin Endocrinol Metab 2007 Mar 13; [Epub ahead of print]17. Oktem O, Paduch D, Xu KP, Mielnik A, Oktay K. Normal Female Phenotype and OvarianDevelopment Despite the Ovarian Expression of Sex Determination Region of YChromosome (SRY) in 46, XX/69, XXY Diploid/Triploid Mosaic Child Conceived AfterIVF-ICSI. J Clin Endocrinol Metab, 2007 Mar; 92(3): 1008-14. Epub 2006 Dec.12.18. Martin JR, Kodaman P, Oktay K, Taylor H. Ovarian Cryopreservation with Transpositionof a Contralateral Ovary: A Combined Approach for Fertility Preservation in WomenReceiving Pelvic Radiation. Fertil Steril. 2007 Jan; 87(1): 189. e5-7. Epub 2006 Nov 1:19. Oktay K, Oktem O, Reh A, Vahdat L. Measuring the Impact of Chemotherapy on Fertilityin Women with Breast Cancer. J Clin Oncol. 2006 Aug 20; 24(24): 4044-6.7

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG20. Oktay K, Hourvitz A, Sahin G, Oktem O, Safro B, Cil A, Bang H. Letrozole ReducesEstrogen and Gonadotropin Exposure in Women with Breast Cancer Undergoing OvarianStimulation Before Chemotherapy. J Clin Endocrinol Metab 2006 Oct; 91(10): 3885-90.Epub 2006 Aug 1.21. Oktay K, Cil A, Bang H. The Efficiency of Oocyte Cryopreservation: A Meta-Analysis.Fertil Steril. 2006 Jul; 86(1): 70-80.22. Oktay K. An Individualized Approach to Fertility Preservation in Women with Cancer. JSupport Oncol. 2006 Apr; 4(4): 181-2, 184.23. Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, Beck LN,Brennan LV, Oktay K. American Society of Clinical Oncology Recommendations onFertility Preservation in Cancer Patients. J Clin Oncol. 2006 Jun 20; 24(18): 2917-31. EpubMay 1.24. Oktay, K. Spontaneous conceptions and live birth after heterotopic ovariantransplantation: is there a germline stem cell connection? Hum Reprod. 2006 Jun; 21(6):1345-8.Epub 2006 Feb 3.25. Sonmezer M & Oktay K. Fertility Preservation in Young Women Undergoing BreastCancer Therapy. The Oncologist. 2006 May; 11(5): 422-34.26. Oktay K. Options for preservation of fertility in women.N Engl J Med. 2005 Sep 29; 353(13): 1418-20.27. Akar M & Oktay K. Restoration of ovarian endocrine function by ovarian transplantation.Trends Endocrinol Metab.2005 Oct; 16(8): 374-80.28. Shamonki MI, Oktay K. Oocyte and ovarian tissue cyropreservation: indications,techniques, and applications. Semin Reprod. Med. 2005 Aug; 23(3): 266-76.29. Sonmezer M, Shamonki MI, Oktay K. Ovarian tissue cryopreservation: benefits and risks.Cell Tissue Res. 2005 Oct; 322(1); 125-32. Epub 2005 Nov 3.30. Oktay K. Further evidence on the safety and success of ovarian stimulation withLetrozole and Tamoxifen in breast cancer patients undergoing IVF to cryopreserve theirembryos for fertility preservation. J Clin Oncol. 2005 Jun 1; 23(16): 3858-9.31. Oktay K. Fertility preservation: an emerging discipline in the care of young patients withcancer. Lancet Oncol. 2005 Apr; 6(4): 192-3.32. Oktay K. Successful human ovarian autotransplantation to the upper arm. Cancer. 2005May; 103(9): 1982-3.33. Roberts J & Oktay K. Fertility preservation: a comprehensive approach to the young8

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGAnnual Meeting of the American Society for Reproductive Medicine (ASRM),Washington, DC, October 13-17, 200797. A. Elassar, O. Oktem, K. Oktay. Fertility Preservation with Ovarian Cryopreservation: ADecade of Experience. Presented at the 63 rd Annual Meeting of the American Society forReproductive Medicine (ASRM), Washington, DC, October 13-17, 200798. A. Azim & K. Oktay. Safety of Ovarian Stimulation with Letrozole and Gonadotropins inBreast Cancer Patients Undergoing Embryo or Oocyte Cryopreservation: A ProspectiveControlled Study. Presented at the 63 rd Annual Meeting of the American Society forReproductive Medicine (ASRM), Washington, DC, October 13-17, 200799. K Oktay & O Oktem. Evidence for primordial follicle regeneration post-chemotherapy inhuman ovarian xenografts. Presented at the 54 th Annual Meeting of the Society forGynecological Investigation (SGI), Reno, NV, March 14-17, 2007.100. H. Kang, D. Reichman, H. Liu, S. Spandorfer, Z. Rosenwaks, K. Oktay. Howmuch “coasting” can a follicle withstand? FSH levels may predict success in IVF patients.Presented at the 62 nd Annual Meeting of the American Society for Reproductive Medicine(ASRM), New Orleans, LA, October 21-25, 2006101. O. Oktem, H. Liu, K. Oktay. Evidence for altered ovarian stromal function inwomen previously exposed to chemotherapy. Presented at the 62 nd Annual Meeting of theAmerican Society for Reproductive Medicine (ASRM), New Orleans, LA, October 21-25,2006102. O. Oktem, K. Oktay. Histological quantification of the impact of chemotherapy onhuman primordial follicle reserve in women. Presented at the 62 nd Annual Meeting of theAmerican Society for Reproductive Medicine (ASRM), New Orleans, LA, October 21-25,2006103. O. Oktem, M. Turkekul, K. Xu, Z. Rosenwaks, K. Oktay. Normal femalephenotype and ovarian development despite the gonadal expression of sex determiningregion of Y chromosome (SRY) in a 46, XX/69, XXY diploid/triploid mosaic childconceived after IVF-ICSI. Presented at the 62 nd Annual Meeting of the American Societyfor Reproductive Medicine (ASRM), New Orleans, LA, October 21-25, 2006104. O. Oktem, D. Sezen, K. Oktay. Correlation of Antimullerian Hormone Levels withPrimordial Follicle Count in Human Ovary. Presented at the 62 nd Annual Meeting of theAmerican Society for Reproductive Medicine (ASRM), New Orleans, LA, October 21-25,2006105. K. Oktay, O. Oktem. A novel ovarian xenografting model to characterize theimpact of chemotherapy agents on human primordial follicle reserve.Presented at the 62 nd Annual Meeting of the American Society for Reproductive Medicine(ASRM), New Orleans, LA, October 21-25, 200614

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG106. A. E. Reh, O. Oktem, K. Lostritto, K. Oktay. Impact of breast cancerchemotherapy on ovarian reserve: a prospective analysis by menstrual history and ovarianreservemarkers.Presented at the 62 nd Annual Meeting of the American Society for Reproductive Medicine(ASRM), New Orleans, LA, October 21-25, 2006107. K. Oktay, A. A. Azim, G. Sahin, H. Yin, N. Zaninovic, L. Veeck-Gosden. In vitromaturation increases the number of oocytes and embryos cryopreserved from cancerpatients undergoing controlled ovarian hyperstimulation (COH) prior to chemotherapy.Presented at the 62 nd Annual Meeting of the American Society for Reproductive Medicine(ASRM), New Orleans, LA, October 21-25, 2006108. A. A. Azim, K. Lostritto, K. Oktay. The First Live Birth After the Use of AromataseInhibitors for Induction of Ovulation in Young Women with Endometrial carcinoma.Presented at the 62 nd Annual Meeting of the American Society for Reproductive Medicine(ASRM), New Orleans, LA, October 21-25, 2006109. A. A. Azim, G. Schattman, K. Oktay. Fertility preservation in young women diagnosedwith cervical carcinoma. Presented at the 62 nd Annual Meeting of the American Society forReproductive Medicine (ASRM), New Orleans, LA, October 21-25, 2006110. A. A. Azim, M. Costantini-Ferrando, K. Lostritto, K. Oktay. Comparative potency ofanastrozole to suppress estradiol levels in breast cancer patients undergoing controlledovarian stimulation prior to IVF: A pilot dose-finding study. Presented at the 62 nd AnnualMeeting of the American Society for Reproductive Medicine (ASRM), New Orleans, LA,October 21-25, 2006111. A. A. Azim, E. R. Rauch, M. Ravich, S. Witkin, K. Oktay. Ovarian reserve is impaired incancer patients with normal baseline FSH who previously received chemotherapy asdetermined by response to controlled ovarian stimulation and anti-mullerian hormonemeasurements: a controlled study. Presented at the 62 nd Annual Meeting of the AmericanSociety for Reproductive Medicine (ASRM), New Orleans, LA, October 21-25, 2006112. K. Oktay, N. Libertella, O. Oktem, L. Beck, A. Cil, The Impact of Paclitaxel onMenstrual Function. Presented at the 28 th Annual San Antonio Breast Cancer Symposium,San Antonio, TX, December 8-11, 2005113. R. G. Gosden, G. Morris, H. Yin, R. J. Bodine, K. Oktay Relationship between structurein the frozen state and viability of thawed ovarian tissue after cryopreservation. Presentedat the 61 st Annual Meeting of the American Society for Reproductive Medicine (ASRM),Montreal, Quebec, Canada, October 15-19, 2005114. Roberts J, Nikopoulos S, Oktem O, Rosenwaks Z, Giancotti F, Oktay K. Integrin beta-4signalling plays a key role in mouse embryogenesis. Presented at the 61 st Annual Meetingof the American Society for Reproductive Medicine (ASRM), Montreal, Quebec, Canada,15

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGOctober 15-19, 2005. (CFS Prize Paper).115. Oktem O and Oktay K. In vitro growth and survival of mouse preantral follicles indifferent culture conditions: role of extracellular matrix, activin-A and mitogen activatedprotein kinase pathways. Presented at the 61 st Annual Meeting of the American Society forReproductive Medicine (ASRM), Montreal, Quebec, Canada, October 15-19, 2005.116. Akar M, Lui H, Oktay K. Serum FSH Measurements on the day of hCG administrationmay predict pregnancy outcome in women undergoing “coasting” during IVF-FET cycles.Presented at the 61 st Annual Meeting of the American Society for Reproductive Medicine(ASRM), Montreal, Quebec, Canada, October 15-19, 2005.117. K. Oktay, A.P. Cil, O. Oktem, H. Bang. Continuous combined Letrozole-FSHstimulation Requires less FSH with similar outcomes compared to standard ovarianstimulation regimens for IVF. Presented at the 61 st Annual Meeting of the AmericanSociety for Reproductive Medicine (ASRM), Montreal, Quebec, Canada, October 15-19,2005.118. M. Sonmezer, M.E. Akar, K. Oktay. Strong family history in women who werediagnosed with breast cancer after in vitro fertilization. Presented at the 61 st AnnualMeeting of the American Society for Reproductive Medicine (ASRM), Montreal, Quebec,Canada, October 15-19, 2005.119. K. Oktay, A.P. Cil, L. Veeck, H. Bang . Comparative efficiency of IVF between frozenthawedand fresh oocytes: a meta-analysis. Presented at the 61 st Annual Meeting of theAmerican Society for Reproductive Medicine (ASRM), Montreal, Quebec, Canada,October 15-19, 2005.120. K. Oktay, N. Libertella, E. Buyuk, K. Lostritto, A. Vickers & M. Akar. Letrozole andtamoxifen as safer ovarian stimulates in women undergoing embryo cryopreservation forfertility preservation before preservation before breast cancer chemotherapy: A prospectivecontrolled trial. Presented at the 2005 Annual Meeting of the American Society of ClinicalOncology, Orlando, FL, May 13-17, 2005.121. Oktay K, Buyuk E, Akar M, Rosenwaks Z & Libertella N. Fertility preservation in breastcancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifenand letrozole for embryo cryopreservation (General Program and SART Prize PaperCandidate). Presented at the Annual Meeting of the American Society for ReproductiveMedicine, Philadelphia, PA, October 16-20.122. Oktay K. First Case of IVF-embryo transfer after heterotopic Transplantation of LongtermCryobanked Ovarian Tissue. Presented at The 20 th Annual Meeting of ESHRE,Berlin, Germany, June 27-30, 2004.123. Oktay K. Role of extracellular matrix and integrin signaling in ovarian follicledevelopment. Presented at The Endocrine Society’s 86 th Annual Meeting, New Orleans,16

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGLA, June 2004.124. Oktay K& Buyuk E. In Vitro growth of mouse primary and early prenatal follicles in a 3-dimensional culture system. Presented at the 59 th Annual Meeting of the American Societyfor Reproductive Medicine (ASRM), San Antonio, TX, October 2003.125. Oktay K. A prospective comparison of Tamoxifen alone and Tamoxifen-FSH combinedprotocol for IVF and fertility preservation in breast cancer patients. Presented at the 59 thAnnual Meeting of the American Society for Reproductive Medicine (ASRM), SanAntonio, TX, October 2003.126. Oktay K. Decipherine early follicle folliculogenesis: Jun Amino Terminal Kinase (JNK)plays a key role in preantral follicle growth. Presented at the 59 th Annual Meeting of theAmerican Society for Reproductive Medicine (ASRM), San Antonio, TX, October 2003.127. Oktay K. Novel use of an aromatase inhibitor for fertility preservation via embryocryopreservation in endometrial cancer: A Case Report. Presented at the 59 th AnnualMeeting of the American Society for Reproductive Medicine (ASRM), San Antonio, TX,October 2003.128. Buyuk E, Oktem O, Robberts J, Rosenwaks Z, Oktay K. In Vitro growth of mouseprimary and early preantral follicles in a 3-dimensional culture system. To be presented atthe 58 th Annual Meeting of the American Society for Reproductive Medicine (ASRM), SanAntonio, Texas, October 2002.129. Oktay K , Buyuk E, Davis OK, Veeck L, Rosenwaks Z. A prospective comparison ofTamoxifen alone and Tamoxifen-FSH combined protocol for IVF and fertility preservationin breast cancer patients. To be presented at the 58 th Annual Meeting of the AmericanSociety for Reproductive Medicine (ASRM), San Antonio, Texas, October 2002.130. Oktay K, Buyuk E, Rosenwaks Z. Use of an aromatase inhibitor for fertility preservationvia embryo cryopreservation in endometrial cancer: A Case Report. To be presented at the58 th Annual Meeting of the American Society for Reproductive Medicine (ASRM), SanAntonio, Texas, October 2002.131. Oktay K & Oktay M. Does integrin signaling initiate primordial follicle growth. Presentedat the 50 th Annual Meeting of the Society of Gynecologic Investigation, Washington, DC,March 2002.132. Buyuk E, Oktay M, Rosenwaks Z, Giancotti F, Oktay K. Extracellular matrix -activininteractions in granulosa cell growth and apoptosis (SART Prize Paper Candidate).Presented at the 58 th Annual Meeting of the American Society for Reproductive Medicine(ASRM), Seattle, Washington, October 2002.133. Oktay K, Akman O, Buyuk E, Rosenwaks Z, Giancotti F. Activin responsiveness isdependent on adhesion to extracellular matrix in spontaneously immortalized granulosa17

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGcells (SIGC). Presented at the 58 th Annual Meeting of the American Society forReproductive Medicine (ASRM), Seattle, Washington, October 2002.134. Oktay K, Buyuk E, Davis O, Rosenwaks Z. Fertility preservation in breast cancer patients:in vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifen.Presented at the 58 th Annual Meeting of the American Society for Reproductive Medicine(ASRM), Seattle, Washington, October 2002.135. Oktay K, Buyuk E, Akman O, Oktay M, Rosenwaks Z, Giancotti F. Characterization ofintegrin expression and signaling in a spontaneously immortalized rat granulosa cell line(SIGC). Presented at the 49 th Annual Meeting of the Society of Gynecologic Investigation,Los Angeles, CA, March 2002.136. Oktay K, Rucinski J, Kliot D, Rosenwaks Z. Spontaneous ovulation and menstruationfollowing ovarian transplantation to the forearm. Presented at the 57 th annual Meeting ofASRM, Orlando, Florida, October 21-26, 2001.137. Oktay K, Kan M, Veeck L, Rosenwaks Z. Long term follow and oocyte retrieval afterovarian transplantation in the forearm. Presented at the 48 th Annual Meeting of Society ofGynecological Investigation, Toronto, Canada, March 14-17, 2001.138. Oktay K, Kan M, Veeck L, Rosenwaks Z. Subcutaneous ovarian transplantation to theforearm and percutaneous oocyte retrieval (1 st Prize Video). Presented at the 56 th annualMeeting of ASRM, San Diego, CA, October 21-26, 2000.139. Oktay K, Aydin BA, Economos K, Rucinski J. Restoration of ovarian function afterautologous transplantation of ovarian tissue in the forearm. Presented at the 56 th annualMeeting of ASRM, San Diego, CA, October 21-26, 2000.140. Oktay K, Karlikaya G, Gosden RG, Schwarz RS. Ovarian function after autologoustransplantation of frozen banked human ovarian tissue. Presented at the “Late BreakingNews” section of the 55 th annual meeting of ASRM, Toronto, Ontario, Canada, September25-30,1999.141. Oktay K, Karlikaya G, Aydin B, Schwarz RS. First case of autologous-orthotopictransplantation of frozen-banked human ovarian tissue using a laparoscopic technique(Prize-vVideo). Presented at the 55 th annual meeting of ASRM, Toronto, Ontario, Canada,September 25-30,1999.142. Oktay K, and Karlikaya G. First case of autologous-heterotopic transplantation of freshhuman ovarian tissue (prize-video). Presented at the 55 th annual meeting of ASRM,Toronto, Ontario, Canada, September 25-30,1999.143. Oktay K, Karlikaya G, Akman O, Ojakian G, Oktay MH. Extracellular matrix and activinainteraction: a novel concept in initiation of follicle growth: Presented at the 55 th annualmeeting of ASRM, Toronto, Ontario, Canada, September 25-30,1999.18

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG144. Oktay K, Newton H and Gosden RG. Transplantation of banked human ovarian tissueresults in initiation of follicular growth in SCID mice. Presented at the 54th annualmeeting of ASRM, San Francisco, CA, October 2-9, 1998.145. Oktay K, Karlikaya G, Bayrakceken A. New strategies in studying ovarian aging.Presented at the “Biology of Menopause” Symposia, Serono, New Port Beach, CA,September 10-14.146. Oktay K. Novel approaches to study follicle growth initiation in the human ovary.Presented at the XIIth Ovarian Workshop: Molecular and genetic approaches to studyovarian function, Houston, Texas, August 5-7, 1998.147. Oktay K and Bayrakceken A. Role of cyclin-dependent kinase inhibitors in initiation offollicular growth in the mouse ovary. Presented at the 45th annual meeting of Society forGynecologic Investigation (SGI), Atlanta, GA, March 11-14, 1998.148. Oktay K, Schenken RS, Nelson JF. The effects of long-term gonadotropin administrationon ovarian follicular reserve in the mouse ovary. Presented at the 44th annual meeting ofSociety for Gynecologic Investigation (SGI), San Diego, CA, March 19-21, 1997.149. Briggs D, Miller D, Nugent D, Oktay K and Gosden RG. New strategies for investigatingthe molecular biology of gametogenesis. Presented at the annual meeting of BritishFertility Society, Edinburgh, Scotland, December 1996.150. Gosden RG, Oktay K and Rutherford A. Ovarian tissue banking (Prize-Video, Best Videoof ASRM). Presented at the 52nd annual meeting of ASRM as the prize video, Boston,MA, November 2-7, 1996.151. Oktay K, Briggs D and Gosden RG: Demonstration of FSH receptor mRNA in isolatedhuman primary follicles using the nested polymerase chain reaction. Presented at the 52ndannual meeting of ASRM, Boston, MA, November 2-7, 1996.152. Oktay K, Johnson N, Thomas D, House A, Batchelor A and Lilford R: Tissue expansionvaginoplasty for vaginal agenesis: Psychosexual and surgical outcome. Presented at the52nd annual meeting of ASRM, Boston, MA, November 2-7, 1996.153. Oktay K and Gosden RG: Human primordial follicles can grow to early antral stage in anovel xenograft model using the hpg/SCID mouse (Society of ReproductiveEndocrinologists Prize Paper Candidate). Presented at the 52nd annual meeting of ASRM,Boston, MA, November 2-7, 1996.154. Oktay K, Nugent D and Gosden RG: Isolation, characterization and culture of humanprimordial follicles from fresh and cryopreserved human ovarian tissues. Presented at theEuropean Society of Human Reproduction and Embryology annual meeting, Maastricht,Netherlands, June 30 - July 30, 1996.19

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG155. Oktay K, Nugent D, Salha O and Gosden RG: Isolation and characterization of primordialfollicles from fresh and cryopreserved human ovarian tissues. Presented at the BritishFertility Society meeting, Cardiff, Wales, April 10-12, 1996.156. Oktay K, Montoya I, Nelson JF and Schenken RS: Evidence for theca cell proliferation byproliferating cell nuclear antigen expression coincident with the onset of follicular growth.Presented at the 51st annual meeting of ASRM, Seattle, Washington, October 7-12, 1995.157. Oktay K, Brzyski RG, Berkowitz P and Schenken RS: Preovulatory follicle number andsize as a function of pregnancy rate and outcome in clomiphene citrate treatment cycles.Presented at the 42nd annual meeting of the SGI, Chicago, Illinois, March 16-18, 1995.158. Oktay K, Isik A, Montoya I, Schenken RS and Nelson JF: Proliferating cell nuclearantigen (PCNA) as a marker of granulosa cell proliferation during folliculogenesis in therat. Presented at the 50th annual meeting of the American Fertility Society (now ASRM),San Antonio, Texas, November 5-10, 1994.159. Oktay K, Nelson JF, Montoya I, Isik A and Schenken RS: Demonstration of granulosacell proliferation in the prepubertal rat using the proliferating cell nuclear antigen (PCNA).Presented at the 50th annual meeting of the AFS, San Antonio, Texas, November 5-10,1994.160. Oktay K, Montoya I, Isik A, Schenken RS and Nelson JF: Proliferating cell nuclearantigen as a marker of granulosa cell proliferation and oocyte growth duringfolliculogenesis in cycling and PMSG-stimulated rats. Presented at the Xth OvarianWorkshop: Frontiers in Ovarian Research. The University of Michigan, Ann Arbor,Michigan, July 21-23, 1994.161. Oktay K, Burns WN, Tekmal R and Schenken RS: Comparison of immediatelypreovulatory levels of granulosa cell alpha-inhibin mRNA expression in poor respondersand good responders in an IVF-ET program. Presented at the 41st annual meeting of theSGI, Chicago, Illinois, March 22-26, 1994.162. Oktay K and Krugman D. Association of β-hCG with trophoblastic mass and myosalpinxinvasion in ampullary ectopic pregnancy. Presented at the ACOG Junior Fellow District Imeeting, Portland, Maine, September 18, 1993.163. Oktay K, Manzi D and Luciano AA. GnRH challenge test using the GnRH pump.ESHRE-HUMS Reproductive Endocrinology Meeting, Cappadocia, Turkey, May 19-23,1993.20

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGSELECTED INVITED LECTURES, ROUND-TABLES AND SYMPOSIA1. “Preserving Fertility in Cancer Patients: Options and Outcomes”, Invited Speaker, 4 thAnnual Helene Madeira Breast Cancer Symposium, The Walter and Leonore AnnenbergCenter for Medical Education at Lankenau Hospital, Philadelphia, PA, April 5. 20082. “Human Ovarian Transplantation”, Keynote Speaker, 12 th Biennial Meeting of the UnidadMedica De Alta Especialidad En Gineco Obstetricia, Mexico City, Mexico, March 13,2008.3. “Recent Developments in Assisted Reproduction”, Invited Speaker, 12 th Biennial Meetingof the Unidad Medica De Alta Especialidad En Gineco Obstetricia, Mexico City, Mexico,March 13, 2008.4. "Ovarian Transplantation: A Procedure Born at New York Methodist Hospital", GrandRounds, Department of Surgery, New York Methodist Hospital, Brooklyn, NY, March 11,2008.5. “Fertility Preservation for Cancer Patients”, Keynote Speaker, Approaches toHematology/Oncology: Care and Screening for Primary Care Physicians, 5 th AnnualInteractive Spring Conference, Loyola University Chicago Stritch School of Medicine andLoyola Cancer Care & Research Center, Chicago, Illinois, March 8, 2008.6. “Fertility Preservation for Breast Cancer Patients: State of the Science”, , Invited Speaker ,National Consortium of Breast Centers (NCNC) 18 th Annual National InterdisciplinaryBreast Center Conference, Las Vegas, Nevada, March 1, 2008.7. “Fertility Preservation Before Cytotoxic Treatments”, Grand Rounds, Department ofHematology & Oncology, New York Medical College, Valhalla, NY, January 17, 2008.8. “Future of Fertility Preservation” Grand Rounds, Department of Obstetrics & Gynecology,New York Medical College, Valhalla, NY, January 10, 2008.9. “Putting Fertility on Ice: What the Future Holds”, Invited Speaker, International OvarianConference 2007, Hakone, Japan, November 2-3, 200710. “How Fast Should We Freeze Oocytes? Vitrification vs. Controlled Rate” InteractiveSession”, Chair and Speaker, American Society for Reproductive Medicine AnnualMeeting, Washington, DC, October 16, 200711. “Fertility Preservation: Biological Basis, Procedures, and Genetic Consequences”Postgraduate Course Chair and Speaker, American Society for Reproductive MedicineAnnual Meeting, Washington, DC, October 14, 200712. “ The Ovary: Anatomy and Function throughout Human Life”, “Stem Cells: A21

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGPerspective on Oocytes”, Invited Speaker, Human Reproduction in 2007, Mykonos,Greece, October 1-3, 200713. “Ovarian Stimulation in Cancer Patients”, Invited Speaker, 2 nd International IVICongress, Barcelona, Spain, September 19-21, 200714. “Ovarian Stimulation in Cancer Patients for Cryopreservation of Oocytes and Embryos”,Invited Speaker, 3 rd World Congress on IVM, Montreal, Canada, September 17, 200715. “Emerging Assisted Reproduction Strategies to Preserve Fertility in Cancer Patients”,Invited Speaker, Kansas Masonic Cancer Research Institute, Kansas City, KS, June 19,200716. “Fertility Preservation”, Invited Speaker, Grand Rounds, St. Vincent Medical Center,Bridgeport, CT, June 12, 200717. “Ovarian Stimulation Before and After Cancer Treatment”, Invited Speaker, MidwestReproductive Symposium, Chicago, IL, May 8-9, 200718. “Novel Approach to Controlled Ovarian Stimulation in IVF” and “OoocyteCryopreservation-The Next Breakthrough in ART”, Invited Speaker, 7 th InternationalCongress of the Turkish-German Gynecological Association, Antalya, Turkey, May 16-20, 200719. “Fertility Issues Associated with Breast Cancer Patients”, Invited Speaker, 8 th AnnualMeeting of the American Society of Breast Surgeons, Phoenix, AZ, May 2-6, 200720. “Fertility Preservation in Children and Young Females”, Invited Speaker, Grand Rounds,Mount Sinai School of Medicine, New York, NY, April 26, 200721. “Fertility Preservation Options: The Future is Now”, Invited Speaker, 3 rd Annual FertilityAwareness Health Fair, Orlando, FL, April 22, 200722. “Fertility Preservation Options: Oocyte Cryopreservation” and “Ovarian Stimulation inCancer Patients”, Invited Speaker, Florida Society of Reproductive EndocrinologyAnnual Meeting, Orlando, FL, April 21, 200723. “Preserving Fertility in Cancer Patients” and “ Oocyte Cryopreservation: Current State ofthe Technology”, Invited Speaker, 39 th Annual Matt Weis Symposium, St. Loius, IL,April 19-20, 200724. “Recent Progress in Gamete, Embryo, and Ovarian Tissue Cryopreservation for FertilityPreservation”, Invited Speaker, The Miami Obstetrical and Gynecological Society,Miami, FL, April 11, 200725. “Fertility Preservation in People with Cancer: Tackling Possibly the Most Common22

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGKnown Cause of Gonadal Failure in the 21 st Century”, Invited Speaker, MassachusettsGeneral Hospital/Harvard Medical School, Boston, MA, April 6,2007.26. “American Society of Clinical Oncology Clinical Practice Guideline: FertilityPreservation in People Treated for Cancer” and “”ovulation Induction Before and AfterBreast Cancer”, Invited Speaker, International Symposium on Cancer & Reproduction,Valencia, Spain, March 5-27, 200727. “Current Progress in Fertility Preservation”. Invited Speaker, Monthly Lecture Series,Beth Israel Deaconess Medical Center/ Boston IVF, Boston, MA, March 21, 200728. “Debate: ART and Cryopreservation vs. GnRH Analogs for Fertility Preservation”,Invited Speaker, 54 th Annual Meeting of the Society for Gynecological Investigation,Reno, NV, March 16, 2007.29. “Fertility Preservation Methods in Cancer Patients”, Invited Speaker, Swiss Society ofGynecology, Congress Neuchatel, Switzerland, March 9-10, 200730. “Fertility and Breast Cancer”, Invited Speaker, Adelphi NY Statewide Brest CancerHotline and Support Program, Adelphi University, Garden City, NY, March 5, 200731. “Preserving Fertility After Breast Cancer Treatment”, Invited Speaker, Memorial SloanKettering Cancer Center- Breast Service, New York, NY, February 13, 200732. “Fertility Preservation: A Decade of Progress”, Invited Speaker, Grand Rounds, AlbertEinstein College of Medicine, Bronx, NY, January 30, 200733. “Fertility Preservation Research: Where are we now?”, Invited Speaker, CancerPrevention and Control Colloquia Series, Bethesda, MD, January 24, 200734. “The Current State of Fertility Preservation: A Brief Overview”, Invited Speaker,Fertility Preservation Advisory Panel Meeting, Bethesda, MD, January 23, 200735. “Current Approach to Fertility Preservation in Cancer Patients”, Invited Speaker, GrandRounds, Roswell Park Cancer Institute, Buffalo, NY, December 15, 200636. “ Non-Turner Premature Ovarian Failure: An Evidence Based Approach”, InvitedSpeaker, Grand Rounds, The Hospital of Central Connecticut, New Britain, CT,November 15, 200637. “Fertility Preservation”, Invited Speaker, Greater Hartford Ob/Gyn Society, Farmington,CT, November 14, 200638. “Fertility Preservation: Present and Future”, Postgraduate Course Chair and Speaker,American Society for Reproductive Medicine Annual Meeting, New Orleans, LA, October21, 2006.23

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG39. “Prevention and Management of the Reproductive Consequences of Cancer Treatment”,Program Director’s Choice Symposium, Chair and Speaker, American Society forReproductive Medicine Annual Meeting, New Orleans, LA, October 24, 2006.40. “Is Oocyte Cryopreservation the Next Breakthrough in ART?-Interactive Session”, Chairand Speaker, American Society for Reproductive Medicine Annual Meeting, New Orleans,LA, October 25, 2006.41. “Alternative Ovarian Stimulation Protocols for Cancer Patients”, Roundtable Speaker,Annual meeting of American Society for Reproductive Medicine, New Orleans, LA,October 23, 2006.42. “ Molecular and Clinical Strategies to Preserve Gonadal Function in Females”, InvitedSpeaker, Reproductive Physiology/Endocrinology Seminar, Ithaca, NY, October 11,200643. “Assisted Reproduction Techniques for Young Women with Cancer: What is Feasible,What is Safe?” Invited panel participant. 3 rd Biennial Cancer Survivorship ResearchConference: Embrace the Future, Bethesda, MA, October 4-6, 200644. “Biological Basis and Diagnostic Approach to 46XX Premature Ovarian Failure” &“Fertility Preservation: Where are we now?” Invited Speaker, Seattle GynecologicalSociety-Fall Assembly, Seattle, WA, September 28-29, 200645. “Ovarian Cryopreservation: Latest Insights”, Invited Speaker, “Delivering success: thenext decade-A celebration of ten years of Puregon”, Athens, Greece, September 22-23,200646. “Fertility Preservation and Infertility Treatment in Breast Cancer Patients” & “OvarianTransplantation in Extra Pelvic Organs” Invited Speaker, Reproduction and MalignantDisease, Barcelona, Spain, September 15-16, 200647. “Ovarian Transplant” & “Ovarian cryopreservation: where are we now?” InvitedSpeaker, The 6 th International Congress “Selected Topics on Climacteric Medicine”,Mexico City, Mexico, August 24-26, 200648. “Cryopreservation and Germ Stem Cells: What is the Connection?” Invited Speaker, The5 th Biannual Meeting of Pacific Rim Society for Fertility and Sterility, Seoul, Korea, June9-10, 200649. “Forever Young: Are Stem Cells a Possibility?” Keynote Speaker, European Menopauseand Andropause Society Annual Meeting 2006, Istanbul, Turkey, June 3-7, 200650. “Assisted Reproduction Techniques in the Cancer Survivor: What is Feasible, What isSafe”, Invited Speaker, American Society of Clinical Oncology 2006, Atlanta, GA, June24

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG2-6, 200651. “The Current State of Fertility Preservation: From Cryopreservation of Gametes to GermStem Cell Transplantation”, Invited Speaker, Midwest Reproductive Symposium,Chicago, IL, May 19-21, 200652. “Stimulation in Patients with Medical History or Risk Factors for Cancer”, InvitedSpeaker, Regulation of Follicle Development and Its Clinical Implication, SeronoSymposia International Foundation, Beaune, France, May 12-13 200653. “Modern Preservation of Fertility” Invited Speaker, 2006 Pediatric Adolescent EndocrineSociety (PAS) Annual Meeting, San Francisco, CA, April 28-May2, 200654. “Cryopreservation Technologies for when Cancer and Genetic Diseases ThreatenFertility”, Invited Speaker, NYS Genetics Task Force Meeting, New York, NY, April 26 ,200655. Invited panel participant: Considerations of long-term effects;Health-Related Quality of Life. Adolescent and Young Oncology Progress Review Group(AYAO-PRG) National Cancer Institute, Denver, Colorado, April 24-26, 200656. “Application of Cryopreservation and Germ Stem Cell Technologies to Preserve OvarianFunction in Women” Invited Speaker, ASPIRE (Asian Pacific Infertility & ReproductiveEndocrinology Society) Annual CONGRESS 2006, Changsha, China, March 31-April 2,200657. “Contemporary Approach to Preservation of Fertility in Cancer Patients”, Grand Roundsat Memorial Sloan Kettering Cancer Center, New York, NY, March 31, 200658. “Fertility Issues in the Young Women with Breast Cancer” Invited Speaker, BreastCancer in the Young Woman: It’s the same, but different, Columbia University/NewYork Presbyterian Hospital, New York, NY, March 30, 200659. “Fertility Preservation Strategies: Ovarian Tissue Cryopreservation and Beyond”,Georgetown University Hospital Grand Rounds, Washington D.C., March 15, 200660. “Preservation of Ovarian Endocrine Function in Young Female at Risk for PrematureOvarian Failure”, Saint Barnabas Medical Center Annual Symposium, Livingston NJ,March 9, 200661. “Ovarian Cryopreservation and Transplantation: Recent Developments”, Chicago AreaReproductive Endocrinologists Meeting, Chicago, IL, February 1, 200662. “Approach to Fertility Preservation in Cancer Patients”, Grand Rounds at Beth IsraelHospital, New York, NY, January 4, 200625

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG63. “Guiding the Cancer Patients for the Fertility Preservation: The State of the ART”,Invited Speaker, Northern Westchester Hospital, Mt. Kisco, NY, December 14, 200564. “Current and Emerging Strategies to Preserve Fertility in Young Women with BreastCancer” Invited Speaker, Multidisciplinary Conference, MSKCC, New York, NY,December 13, 200565. “From Ovarian Transplantation to Germ Stem Cell Transplantation: Brave New World ofFertility Preservation”, Invited Speaker, 4 th New England Fertility Society QuarterlyMeeting, Boston, MA, December 6, 200566. “Modern Approach to Preservation of Fertility”, Invited Speaker, The Infant andChildren’s Hospital of Brooklyn at Maimonides Medical Center, Division of PediatricEndocrinology, Brooklyn, NY, November 21, 200567. “Contemporary Approach to Fertility Preservation in Cancer Patients”, Grand Rounds atVanderbilt University Cancer Center, Nashville, TN, November 17, 200568. “Looking into Future: Fertility and Assisted Reproductive Techniques”, Round Table,Women at Risk,/Young Survival Coalition, The Laurie Bass Sklaver Annual Symposium,New York, NY, November 14, 200569. “Fertility Preservation for Young Cancer Survivors”, Invited Speaker, 2005 NationalSociety of Genetic Counselors Annual Educational Conference, Los Angeles, CA,November 12-15, 200570. “Ovarian Transplantation”, Invited speaker, 24 th Annual Congress of Korean MenopauseSociety, Seoul, Korea, November 5-9, 200571. “How to Choose the Best Fertility Preservation Approach for Your Patient”. RoundTable, American Society for Reproductive Medicine Annual Meeting, Montreal, CanadaOctober 18, 2005.72. “Oocyte Cryopreservation”, Symposium Chair & Moderator, Annual Meeting of theAmerican Society for Reproductive Medicine, Montreal, Canada, October 18, 2005.73. “X, Y, The Ovary, and the Testis”, Postgraduate Course Faculty, American Society forReproductive Medicine Annual Meeting, Montreal, Canada, October 15-16, 2005.74. “How to Preserve Ovarian Function”, Invited Speaker, 16 th Annual Meeting NAMS, SanDiego, CA, October 1, 2005.75. “Emerging Assisted Reproduction strategies to Preserve Fertility in Cancer Patients”,Invited Speaker, Kansas Masonic Cancer Research Institute, Kansas City, MO,September 20, 2005.26

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG76. Invited Speaker, The President’s Cancer Panel- Assessing Progress, Advancing Change:Challenges in Cancer Survivorship, Washington, DC, August 26, 2005.77. “Emerging Techniques in Assisted Reproduction”, Invited Speaker, The 23 rd AnnualMeeting of Japan Society of Fertilization and Implantation, Osaka, Japan, August 4-5,2005.78. “Prevention of Chemotherapy Induced Ovarian Failure and Infertility by A.R.T.”, InvitedSpeaker, Sexual Medicine Rounds, Sloan Kettering, New York, NY, July 5, 2005.79. “Emerging Concept in Fertility Preservations”, Invited Speaker, NYU DowntownHospital Residents Graduation Day, New York, NY, June 17, 2005.80. “Preserving Fertility in Breast Cancer Patients”, Invited Speaker, White Plains HospitalBreast Conference, New York, NY, June 21, 2005.81. “Ovarian Transplantation: Choosing the “Right” Technique”, Invited Speaker, 13 thWorld Congress on In Vitro Fertilization, Assisted Reproduction & Genetics, Istanbul,Turkey, May 26-29, 2005.82. “ART for Fertility Preservation”, Invited Speaker, 13 th World Congress on In VitroFertilization, Assisted Reproduction & Genetics, Istanbul, Turkey, May 26-29, 2005.83. “Changing Concepts in Ovarian Follicle Development: Can Ovarian Reserve beRenewed?”, Keynote Speaker, 6 th Annual Meeting of The Turkish & German Society,Antalya, Turkey, May 18-22, 2005.84. “Letrozole and Tamoxifen as Safer Ovarian Stimulates in Women Undergoing EmbryoCryopreservation for Fertility Preservation Before Preservation Before Breast CancerChemotherapy: A Prospective Controlled Trial”, Presented at the 2005 Annual Meetingof the American Society of Clinical Oncology, Orlando, FL, May 13-17, 2005.85. “Clinical Efficacy of Ovarian Cryopreservation”, Invited Speaker, 53 rd Annual Meetingof the Pacific Coast Reproductive Society, Palm Springs, CA, May 4-6, 2005.86. “Preserving Fertility in Women with Breast Cancer”, Invited Speaker, Breast ServiceMultidisciplinary Conference, New York, NY, March 26, 2005.87. “Parenthood After Cancer”, Invited Speaker, American Fertility Association NationalFertility and Adoption Conference, New York, NY, April 17, 2005.88. “Fertility Options for Young Women Post-Treatment”, Invited Speaker, SharsheretSymposium, New York, NY, April 12, 2005.89. “Transplantation in Human”, Invited Speaker, ESHRE 2005 symposium on MammalianOogenesis and Folliculogenesis, Paris, France, March 31-April 2, 2005.27

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG90. “Assisted Reproductive Technologies for Cancer Patients: ART Nouvea”, InvitedSpeaker, Society of Gynecological Oncologist 36 th Annual Meeting – The AnnualMeeting on Women’s Cancer, Miami, FL, March 19-23, 2005.91. “Ovarian Transplantation: Six Years of Progress”, Invited Speaker, 49 th Annual Meetingof the German Society of Endocrinology, Munster, Germany, March 9-11, 2005.92. “Fertility Preservation Strategies for Women”, Invited Speaker. Long Island FertilityNurses, Woodbury, NY, March 2, 2005.93. “Cryopreservation Strategies for Fertility Preservation”, Invited Speaker, Experts inReproductive Medicine Meeting, Naples, FL, February 24-27, 2005.94. “Understanding Your Fertility After Breast Cancer”, Invited Speaker, 5 th AnnualConference for Young Women Affected by Breast Cancer, New York, NY, February 19-20, 2005.95. “Taking Infertility out of Cancer Treatment: Role of cryopreservation techniques”,Invited Speaker, MSKCC Gynecology Service Conference, New York, NY, February 10,200596. “Ovarian Transplantation in Humans: State of Art”, Invited Speaker, Focus onCryopreservation of Human Gametes and Gonadal Tissues, Catania, January 28-29,2005.97. “Cryopreservation Technology for Fertility Preservation”, Invited Speaker, PhiladelphiaReproductive Endocrine Society, Philadelphia, PA, January 6, 2005.98. “Fertility Preservation in Breast Cancer Patients: Misconceptions, Truth and Role ofEmerging Assisted Reproduction (ART) Technologies”, Invited Speaker, San AntonioBreast Cancer Symposium, San Antonio, TX, December 8-11, 2004.99. “Understanding Your Fertility and Pregnancy Options”, Invited Speaker, Living BeyondBreast Cancer, Somerset, NJ, October 30, 2004.100. “Heterotopic Transplantation of Cryopreserved Ovarian Tissue”, ConferenceModerator, Alpha Scientists in Reproductive Medicine Internet Conference, October 27,2004.101. “Fertility After Breast Cancer”, Invited Speaker, Controversies in Breast CancerAdjuvant and Neoadjuvant Therapy: 2004, New York, NY, October 23, 2004.102. “Fertility Preservation: Ovarian Cryopreservation and Beyond”, Round Table,American Society for Reproductive Medicine Annual Meeting, Philadelphia, PA October18, 2004.28

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG103. “Ovarian and Testicular Transplantation: Technical and Ethical Challenges”,Symposium Chair & Moderator, Annual Meeting of the American Society forReproductive Medicine, Philadelphia, PA, October 20, 2004.104. “Fertility Preservation: Present and Future”, Postgraduate Course Chair andSpeaker, American Society for Reproductive Medicine Annual Meeting, Philadelphia, PA,October 16, 2004.105. “Fertility Preservation in Breast Cancer Patients: a Prospective ControlledComparison of Ovarian Stimulation with Tamoxifen and Letrozole for EmbryoCryopreservation”, Presented at the Annual Meeting of the American Society forReproductive Medicine, Philadelphia, PA, October 16-20, 2004.106. “Preserving Prepubertal Ovarian Follicles”, Invited Speaker, Fertility andReproductiveIssues in Survivors of Childhood Cancer, Cape Cod, MA, September 30-October 3, 2004.107. “Ovarian Transplantation and New ART Techniques in Preservation of Fertility”,InvitedSpeaker, 1 st International Congress on reproductive Medicine, Istanbul, Turkey,September 22-25, 2004.108. “Growth Differentiation Factor/Bone Morphogenetic Protein Regulation ofFollicular Development”, Invited Speaker, The Endocrine Society’s 86 th Annual Meeting,New Orleans, LA, June 16-19, 2004.109. “Innovative Techniques in Preserving Fertility in Cancer Patients”, Invited Speaker,Grand Rounds at University of Texas, MD Anderson Cancer Center, Houston, TX, June16, 2004.110. “Emerging Concepts: Strategies to Preserve Fertility for Patients Being Treated forBreast Cancer”, Invited Speaker, 2004 ASCO Annual Meeting, New Orleans, LA, June 5-8, 2004.111. “Potential of Ovarian Tissue Transplantation”, Invited Speaker, Warm Association ofReproductive Medicine, Rome, Italy, May 6-9, 2004.112. “Parenthood After Cancer: Options for Men and Women, Before, During and AfterCancer Treatment”, Invited Speaker, American Infertility Association, New York, NY,April 25, 2005.113. “Ovarian Tissue Cryopreservation”, Invited Speaker, First Moscow InternationalCongress, Scientific Center for Obstetrics, Gynecology & Perinatology Russian Academyof Medical Sciences, Moscow, Russia, April 19-22, 2004.29

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG114. “Ovarian Cryopreservation and Transplantation: The future is brighter”, Invited Speaker,Cleveland Society of Obstetricians and Gynecologists, Cleveland, OH, March 17, 2004.115. “Innovative Approaches in Fertility Preservation”, Invited Speaker. The 4 th Conference ofthe Pacific Rim Society for Fertility and Sterility, Okinawa, Japan, March 8-11, 2004116. “Embryo and Ovarian Tissue Cryopreservation Before Cancer Treatment and use toPreserve Future Fertility”, Invited Speaker, Parenthood After Cancer: Today’s Options andTomorrow’s Hopes Conference, Houston, TX, March 5-7, 2003.117. “ Fertility Preservation In Cancer Patients”, Invited Speaker, Grand Rounds at NorthShore University Hospital, Manhasset, NY, February 18, 2004.118. “Fertility Preservation in Cancer Patients”, Invited Speaker, SMART ART IV, Orlando,FL, August 21-23, 2003.119. “Fertility Preservation in Cancer Patients, Surgical and Non-surgical Approach”, InvitedSpeaker, 1 st International Congress on Ovarian Cryopreservation and OvarianTransplantation, Brussels, Madrid, June 27-28, 2003.120. “ Fertility and Pregnancy After Breast cancer: Options and Strategies”, Invited Speaker,3 rd Annual Meeting of the Living Beyond Breast Cancer & Young Survivor’s Coalition,Philadelphia, PA, February 22, 2003.121. “Fertility Preservation in Cancer Patients”, Invited Speaker, Grand Rounds, Departmentof Obstetrics & Gynecology, University of Pennsylvania, Philadelphia, PA, October 14,2002.122. “Cryopreservation of Oocytes and Ovarian Tissue”, Invited Speaker, BWARE(Baltimore-Washington Area Reproductive Endocrinologists) Meeting, Columbia, MD,October 14, 2002.123. “Fertility Preservation in Pediatric Cancer Patients”, Invited Speaker, Grand Rounds,Department of Pediatrics, Brooklyn Hospital, Brooklyn, NY, November 5, 2002.124. “Can I Still Have Children? Fertility Options After Breast Cancer”, Invited Speaker,Comprehensive Breast Center at St. Luke’s-Roosevelt Hospital, New York, NY, November4, 2002.125. “Fertility Preservation: Current & Future Aspects”, Invited Speaker, Grand Rounds,Stamford Hospital Department of OB/GYN, Stamford, CT, October 25, 2002.126. “Fertility Preservation in Breast Cancer Patients”, Invited Speaker, Sharsharet Symposiumon Fertility after Breast Cancer, New York, NY, October 24,2002.127. “Can Menopause be Reversed with Ovarian Transplantation?”, Round Table, American30

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGSociety for Reproductive Medicine Annual Meeting, Seattle, Washington, October 14,2002.128. “Controversies in Fertility Preservation in Cancer Patients” Symposium Chair &Moderator, Seattle, Washington, October 13, 2002.129. “Controversies and New Developments in Fertility Preservation”, Invited Speaker,Controversies in Fertility Preservation in Cancer Patients Symposium, American Societyfor Reproductive Medicine Annual Meeting, Seattle, Washington, October 13, 2002.130. “Fertility Preservation in Cancer Patients”. Invited Speaker, Weill Medical College-American Hospital of Istanbul Joint Symposium on Assisted Reproduction, IstanbulTurkey, October 1-2, 2002.131. “Oocyte Cryopreservation Techniques”. Invited Speaker, Weill Medical College-American Hospital of Istanbul Joint Symposium on Assisted Reproduction, IstanbulTurkey, October 1-2, 2002132. “Clinical Aspects of Ovarian Transplantation”. Invited Speaker, 3 rd Annual Meeting ofControversies in Obstetrics, Gynecology and Infertility, Washington D.C., June 23, 2002.133. “Autotransplantation of Ovarian Tissue”. Invited Speaker, 3 rd Meeting of WimSchellenkens Foundation: “Reproduction and Cancer, Cancer and Reproduction”, TheHague, Netherlands, June 14, 2002.134. “Cryopreservation and Transplantation of Human Ovarian Biopsies”. Invited Speaker,“Serono Symposium on Biotechnology of Human Reproduction: From Research toClinical Applications”, Turin, Italy, May 10-11, 2002.135. “Transplantation in Reproductive Medicine”. Invited Speaker, Hot Topics in OB/GYNPlenary Session, Annual Meeting of American College of Obstetrics & Gynecology, LosAngeles, California, May 7, 2002.136. “Preservation of Ovarian Endocrine Function in Pediatric Patients”. Grand Rounds,Pediatric Oncology Unit, Columbia University College of Physicians and Surgeons, NewYork, NY, April 29, 2002.137. “ Fertility Preservation”. Workshop, National Annual Meeting of American InfertilityAssociation, New York, NY, April 28, 2002.138. “Ovarian Transplantation in Humans: Techniques and Recent Progress”. Invited Speaker,Serono Symposium: Fertility Preservation in Cancer Patients, Taormina, Italy, April 21-22,2002.139. “Emerging Technologies for Fertility Preservation in Cancer and Surgical Patients”.Grand Rounds, Department of Obstetrics & Gynecology, St. Luke’s Roosevelt Hospital,31

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGNew York, NY, April 9, 2002.140. “An Update on Fertility Preservation in Cancer Patients”. Tomorrow’s World TodaySymposium, Invited Speaker, Tyson’s Corner, VA, March 9, 2002.141. “New Approaches to Preserve Fertility and Ovarian Endocrine Function in CancerSurvivors”. Invited Speaker, Women and Cancer: Issues and Answers, Memorial SloanKettering Cancer Center, New York, NY, March 8 th , 2002.142. “Specific Approaches for Preservation of Fertility in Breast Cancer Patients”. InvitedSpeaker, Breast Oncology Grand Rounds, St Luke’s Roosevelt Hospital, New York, NY,February 25, 2002.143. “Fertility and Pregnancy after Breast Cancer”. Plenary Session Speaker, The 2 nd AnnualConference for Young Women Affected by Breast Cancer, Philadelphia, PA, February23 rd , 2002.144. “Fertility Preservation in Breast Cancer Patients”. Invited Speaker, 29 th Annual BreastCancer Symposium, New York, N.Y., February 2 nd , 2002145. “Fertility Preservation in Chemotherapy and Radiotherapy Patients”. Grand Rounds,Department of Obstetrics & Gynecology, Long Island Jewish Medical Center, Long Island,N.Y., Jan 30, 2002.146. “Ovarian Transplantation Techniques”,Grand Rounds, Department of Obstetrics &Gynecology, University of North Carolina Medical School, Chapel Hill, N.C., Jan 23,2002.147. “Fertility Preservation Strategies for Cancer Patients”. Invited Speaker, Research inProgress Meeting, Division of Reproductive Endocrinology, Yale University MedicalSchool, New Haven, CT, December 24, 2001.148. “Video Symposium on Ovarian Cryopreservation and Transplantation: Options forFertility Preservation in Cancer Patients.” Moderator, Speaker, and Organizer, 57 th AnnualMeeting of ASRM, Orlando, Florida, October 23, 2001.149. “Heterotopic and Orthotopic Ovarian Transplantation Techniques”. Guest Speaker, 1 èrejournée du GRECOT “Cryoconservation du tissu ovarien et préservation de la fertilité Uneréalité pour demain ?” Lyon, France, September 8, 2001.150. “Ovarian Cryopreservation & Transplantation: An Update”. Guest Speaker, ChiefResident’s Day, Department of Obstetrics & Gynecology, Weill Medical College ofCornell University, New York, NY, June 22, 2001.151. “Recent Developments in Ovarian Transplantation”. Plenary Session Speaker, 4 th Meetingof the Turkish-German Gynecologic Association, Antalya, Turkey, May 27 th , 2001.32

Curriculum Vitae, Kutluk H. Oktay, MD, FACOG152. “Blastocyst Culture: A Breakthrough or Selection Bias?” Plenary Session Speaker, 4 thMeeting of the Turkish-German Gynecologic Association, Antalya, Turkey, May 27 th ,2001.153. “Recent Advances in Assisted Reproduction: Cornell Experience”. Guest Speaker, 2 ndInternational Meeting of Ovulation Induction and Assisted Reproduction, Antalya, Turkey,May 3 rd , 2001.154. “An Update on Ovarian Transplantation”. Guest Speaker, 2 nd International Meeting ofOvulation Induction and Assisted Reproduction, Antalya, Turkey, May 3, 2001.155. “New Assisted Reproduction Techniques to Preserve Ovarian Function in Patients withCervical Carcinoma” Grand Rounds, Gynecologic Oncology Group, Memorial SloanKettering Cancer Center, New York, NY, April 5, 2001.156. “Reproductive Strategies to Preserve Ovarian Function in Cancer Patient” Resolve’sCancer and Fertility Meeting, Weill Medical College, New York, NY, February 15, 2001.157. “Recent Advances in Assisted Reproduction”, Grand Rounds, Department of Obstetrics &Gynecology, Brooklyn Hospital Center, Brooklyn, NY, February 13, 2001.158. Recent Clinical Advances in Ovarian Transplantation”, Grand Rounds, New YorkMethodist Hospital, Brooklyn, NY, February 12, 2001.159. “Ovarian Tissue Cryopreservation: Where are we?” Guest Speaker, Pediatric andAdolescent Gynecology Symposia at the Annual Meeting of ASRM, San Diego, CA,October 23, 2000.160. "Recent Advances in Ovarian Tissue Banking and Transplantation". Grand Rounds, Dept.Obstetrics & Gynecology, Mount Sinai School of Medicine, N.Y., September 13, 2000.161. "From primordial follicle to conception: Extending the possibilities in assistedreproduction." Keynote Speaker, 37 th Annual Meeting of Mexican Society ofReproduction, Ixtapa, Mexico, August 2-5, 2000.162. Keynote Speaker, 37 th Annual Meeting of Mexican Society of Reproduction, Ixtapa,Mexico, August 2-5, 2000.163. “Recent Findings in Ovarian Tissue Banking”. Guest speaker, “From Here to Maternity-Reproduction Into the 21 st Century”, Waukesha, WI, May 2000164. “Ovarian Transplantation: Recent Progress”. Grand Rounds, Center for HumanReproduction, Chicago, IL, April 6,2000.165. "Ovarian Transplantation". Guest Speaker, Brooklyn Gynecological Society Meeting,33

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGBrooklyn, NY, February 2000.166. "Ovarian tissue cryopreservation and transplantation". Guest speaker, Serono InternationalSymposia on "Storing Reproduction". Bologna, Italy, October 7-8, 1999.167. "Priorities and new models in ovarian research". Guest speaker and adviser, "FollicleBiology Research Group Symposia", Serono Laboratories, MA, October 1998.168. “Ovarian tissue banking: fact or fancy?" Round table discussion, World Congress ofFertility-ASRM Annual Meeting, San Francisco, CA, October 1998.169. “Isolation and in vitro growth of primordial follicles”. Round table discussion, WorldCongress of Fertility-ASRM Annual Meeting, San Francisco, CA, October 1998.170. “New strategies in studying ovarian aging”. Invited speaker, “Biology of Menopause”Serono Symposia, New Port Beach, CA, September 1998.171. “Ovarian tissue banking: Progress continues”. Invited speaker, 2nd InternationalCongress of Gynecology, Antalya, Turkey, June 1997.172. “Alternative technologies in storage of reproductive tissue”. Research seminars at theDivision of Reproductive Endocrinology, Yale University Medical School, February 1997.173. “Cryopreservation and transplantation of human ovarian tissue”. Grand rounds, SUNYHSC at Brooklyn, Department of Obstetrics & Gynecology, N.Y., December 1996.174. “Ovarian tissue banking”. Panel discussant, postgraduate luncheon, 52nd annual meetingof ASRM, Boston, MA, November 2-7, 1996.175. “Vaginal reconstruction in patients with vaginal agenesis". Grand Rounds, SUNY HSC atBrooklyn, Department of Obstetrics & Gynecology, N.Y., September 1996.176. "Cryopreservation of oocytes and ovarian tissue". Invited speaker, 1 st InternationalCongress of Gynecology, Antalya, Turkey, June 1996.177. "The mysterious primordial follicle: A living mummy?". Grand Rounds, Department ofObstetrics & Gynecology, University of Leeds, UK, March 1996.178. "Current American health care with an emphasis on Obstetrics". The University of LeedsObstetrical Meeting, Leeds, UK, February 1996.34

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGPUBLIC RECOGNITIONRecognized as the first clinician to perform ovarian transplantation with cryopreserved tissue.Credited for and recognized as a pioneer in the establishment of the Fertility Preservation field.Research made news main news and media outlets in the US and over 70 countries since 1999.Received and continue to receive awards from consumer organizations.Over 16,000 citations in Google under “Kutluk Oktay”.Invited Advisory Board Member for numerous patient organizations.PATENTS1. Kutluk Oktay and Rodney Bosley (Cook, Ob-Gyn).Method and Apparatus for Aspirating Oocytes from Transplanted Ovarian Tissue;pending final approval.RESEARCH INTERESTFertility PreservationOvarian tissue cryopreservation and transplantation.Ovarian Biology.Signal transduction and initiation of follicular growth.In vitro growth of primordial follicles.Characterization of the impact of chemotherapeutics on ovarian reserve by animal models andantimullerian hormone measurements.Integrins and Jun Amino Terminal Kinase (JNK) in cell proliferation and embryogenesisRESEARCH GRANTS35

Curriculum Vitae, Kutluk H. Oktay, MD, FACOGPast:Role of gonadotropins in the initiation of primordial follicle growth.August 1995-July 1996; $ 60,000.WellBeing Foundation, London, UK.Cyclin-dependent kinase inhibitor expression in the mouse ovary.July 1996-June 1997; $20,000.Departmental funds, OB/GYN, SUNY HSC, Brooklyn, NY.Role of integrin-mediated signal transduction in the initiation of primordialfollicle growth.Aug. 1996-July 1997; $15,000.American Society for Reproductive Medicine-Mead Johnson.Ovarian tissue banking and transplantation, in vitro maturation of humanprimordial follicles.August 1996-July 2000; $200,000.New York Methodist Hospital/Dept OB/GYN Research Funds.Integrin signaling and anoikis in regulation of early stages of human ovarianfollicular growth.July 1999-July 2001; $ 50,000.American Society for Reproductive Medicine-Serono FoundationIntegrin signaling in ovarian agingJuly 2002 – July 2003; $20,000Cornell Center for Aging Pilot GrantPresent:Integrin signaling in granulosa cell growthFeb 1, 2003 – Jan 31, 2008; $605,000 (direct cost)NICHD Grant # HD043339-01Characterization and prevention of chemotherapy-induced damage toovarian reserveSept 2007 – Aug 2012; $1,125,000 (direct cost)NICHD& NCI Grant # RHD053112A36