FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 97<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
839<br />
Lentiviral Vectors Encoding Connexin43 Mutants<br />
Reduce Gap Junction Function: Toward Molecular<br />
Ablation <strong>of</strong> Re-Entrant Cardiac Arrhythmias<br />
Eddy Kizana, Samantha L. Ginn, Christine Smyth, Anita<br />
Boyd, Stuart P. Thomas, David G. Allen, David L. Ross, Ian<br />
E. Alexander<br />
840<br />
Recombinant Sendai Virus Vectors with Matrix Protein<br />
<strong>Gene</strong> Deletion Restore Dendritic <strong>Cell</strong> Allostimulatory<br />
Activity<br />
Sorin Armeanu, Irina Smirnow, Sascha Bossow, Wolfgang J.<br />
Neubert, Ulrich M. Lauer, Peter Brossart, Michael Bitzer<br />
841<br />
A Cytoplasmic <strong>Gene</strong> <strong>Therapy</strong> with Sendai Virus Vectors:<br />
Reduction <strong>of</strong> Cytopathic and Immunogenic Reaction <strong>of</strong><br />
New Class Cytoplasmic RNA Vector<br />
Makoto Inoue, Hitoshi Iwasaki, Mariko Yoshizaki, Akihiro<br />
Tagawa, Kentaro Washizawa, Takashi Hironaka, Mamoru<br />
Hasegawa<br />
842<br />
Repeated Administration <strong>of</strong> Sendai Virus into Lung<br />
Uta Griesenbach, Gerry McLachlan, Luci Somerton, David<br />
Collie, Makoto Inoue, Takashi Hironaka, Toshiyuki Owaki,<br />
Duncan M. Geddes, Mamoru Hasegawa, Eric W. F. W. Alton<br />
843<br />
The Tupaia Paramyxovirus Envelope as Vector Delivery<br />
Module: Novel Fusion Protein Cleavage-Activation<br />
Sequence and Attachment Protein Retargeting<br />
Christoph Springfeld, Veronika von Messling, Christian A.<br />
Tidona, Gholamreza Darai, Roberto Cattaneo<br />
844<br />
Determinants <strong>of</strong> Viral Tropism: A Morbillivirus V Protein<br />
Exerts Host Defense Evasion Function in T Lymphocytes<br />
Veronika von Messling, Roberto Cattaneo<br />
845<br />
Properties <strong>of</strong> Sindbis Virus Vectors Produced with a<br />
Chimeric Split Helper System<br />
Anna Ketola, Sondra Schlesinger, Jarmo Wahlfors<br />
846<br />
In Vivo and In Vitro <strong>Cell</strong> Targeting with Library-Selected<br />
Protease-Activatable Replication-Competent<br />
Retroviruses<br />
Klaus Cichutek, Richard M. Schneider, Astrid Schwantes,<br />
Yuansheng Sun, Christian J. Buchholz, Irene Hartl, Stephen J.<br />
Russell<br />
AAV Vectors: Vector Development<br />
847<br />
Adeno-Associated Virus Capsids from Divergent AAV<br />
Clades and Subgroup C Adenovirus Capsids Share a<br />
Common Microtubule-Binding Mechanism Relevant to<br />
Virus Trafficking<br />
Samir A. Kelkar, Bishnu P. De, Guangping Gao, James M.<br />
Wilson, Ronald G. Crystal, Philip L. Leopold<br />
848<br />
Development <strong>of</strong> AAV Vectors Targeted to Vascular<br />
Endothelium<br />
Matthew Stachler, Jennette Crumine, Jeffrey Bartlett<br />
849<br />
Transduction <strong>of</strong> Mouse Dendritic <strong>Cell</strong>s Is Enhanced by<br />
Repetitive Infection with Self-Complementary Adeno-<br />
Associated Virus 6 Combined with Immunostimulatory<br />
Ligands<br />
Wayne A. Aldrich, Changchun Ren, April F. White, Shang-<br />
Zhen Zhou, Sanjay Kumar, Connie B. Jenkins, Denise R.<br />
Shaw, Theresa V. Strong, Pierre L. Triozzi, Selvarangan<br />
Ponnazhagan<br />
850<br />
Efficiency <strong>of</strong> Six AAV Serotypes in Transducing Rat<br />
Myocardium In Vivo<br />
Julieta Palomeque, Jennifer A. Wellman, Shangzhen Zhou, Peter<br />
Colosi, Manuel Ramos-Kuri, Federica del Monte, Roger J.<br />
Hajjar<br />
851<br />
Development <strong>of</strong> Organ Homing AAV-2 Vectors<br />
Lorraine M. Work, Stuart A. Nicklin, Nicola Britton, Michael<br />
Hallek, Hildegard Buning, Andrew H. Baker<br />
852<br />
Human ANP32B Protein Binds AAV-2 Rep and Increases<br />
Viral Replication and rAAV Production<br />
Gianluca Pegoraro, Alessandro Marcello, Michael P. Myers,<br />
Mauro Giacca<br />
853<br />
Persistent Expression <strong>of</strong> Single Chain Antibodies Mediated<br />
by AAV5 and AAVrh.10 Vectors<br />
Julie L. Boyer, Jeffrey Howard, Neil R. Hackett, Robert G.<br />
Pergolizzi, James M. Wilson, Ronald G. Crystal<br />
854<br />
Optimization <strong>of</strong> AAV Serotype and Promoter for Increased<br />
Distribution <strong>of</strong> Expression in Both Somatic and<br />
Central Nervous Systems <strong>of</strong> Mice<br />
Haiyan Fu, Joseph Muenzer, Lu Kang, Jerillyn S. Jennings,<br />
Richard J. Samulski, Douglas M. McCarty
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