FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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96<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
Poster Session III<br />
Exhibit Hall 2<br />
RNA Virus Vectors: Safety, Therapeutics<br />
(Note: Abstract 822 has been moved from Poster<br />
Session III to Poster Session I and will follow Abstract<br />
109.)<br />
822<br />
A Rev/RRE Dependent Packaging System for MLV Based<br />
Vectors Raises Biosafety Concerns<br />
Hong Ma, Adam Cockrell, Ryan Bash, Teryy VanDyke, Tal<br />
Kafri<br />
823<br />
Dissecting Overlapping Functions <strong>of</strong> Transcriptional<br />
Enhancer and Polyadenylation in the Lentiviral U3<br />
Qing Yang, Wayne Chou, Lung-Ji Chang<br />
824<br />
Oncoretroviral Vector Integration Biases in Mouse<br />
Hematopoietic Progenitors<br />
Mari Aker, Julie Tubb, George Stamatoyannopoulos, David W.<br />
Emery<br />
825<br />
Product Enhanced Reverse Transcriptase (PERT) Assay<br />
for RCL/RCR Detection<br />
Lakshmi Sastry, Yi Xu, Lisa Duffy, Sue Koop, Aparna Jasti,<br />
Holger Roehl, Doug Jolly, Kenneth Cornetta<br />
826<br />
The Risk <strong>of</strong> Integration: Characterization and Testing <strong>of</strong><br />
<strong>Cell</strong> Lines Engineered for the Study <strong>of</strong> Insertional <strong>Gene</strong><br />
Activation<br />
R. Scott McIvor, Nikunj V. Somia, Andrea D. Converse<br />
827<br />
Integration and Biodistribution Studies <strong>of</strong> Retroviral<br />
Vector in Mouse Gonad Tissues<br />
Gyu Seek Rhee, Ji hyun Seok, Soon Sun Kim, Seung Jun<br />
Kwack, Bo Ra Kim, Rhee Da Lee, Soo Yeong Chae, Young<br />
Hyuk Won, Seung Shin Yu, Dae Hyun Cho<br />
828<br />
Optimizing the Woodchuck Hepatitis Virus Post-<br />
Transcriptional Regulatory Element (WPRE) for Safety<br />
and Function in Lentiviral Vectors<br />
Manij Patel, John C. Olsen<br />
829<br />
Design <strong>of</strong> a Safe and Efficient Vector for Bone Marrow<br />
Chemoprotection by O6-Methyl-Guanine-DNA- MethylTransferase<br />
Axel Schambach, Jens Bohne, Saurabh Chandra, Elke Will,<br />
Lars Mueller, Ge<strong>of</strong>frey Margison, David A. Williams, Christopher<br />
Baum<br />
830<br />
Determination <strong>of</strong> the Pr<strong>of</strong>ile and Site Preference <strong>of</strong><br />
Lentiviral Vector Integration<br />
Caroline V. Hacker, Susan M. Kingsman, Kyriacous A.<br />
Mitrophanous, James E. Miskin<br />
831<br />
Evaluation <strong>of</strong> Lentiviral Vectors for <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong><br />
Wiskott-Aldrich Syndrome<br />
Marguerite V. Evans-Galea, Matthew M. Wielgosz, Hideki<br />
Hanawa, Arthur W. Nienhuis<br />
832<br />
Suppression <strong>of</strong> HIV-1 Replication by Delievery <strong>of</strong><br />
multiple siRNA <strong>Gene</strong>s Against p24, Tat/ Rev and CCR5<br />
Hsin-Lung Lo, Jerry Wu, Tan Chang, Priscilla Yam, John<br />
Zaia, Jiing-Kuan Yee<br />
833<br />
A Preclinical Safety Study <strong>of</strong> Simian Immunodeficiency<br />
Virus (SIV)-Based Lentivirus Vector for Retinal <strong>Gene</strong><br />
Transfer in Non-Human Primates<br />
Yasuhiro Ikeda, Yoshikazu Yonemitsu, Masanori Miyazaki,<br />
Riichiro Kono, Toshinori Murata, Yoshinobu Goto, Toshiaki<br />
Tabata, Yasuji Ueda, Naohide Ageyama, Keiji Terao Mamoru<br />
Hasegawa, Tatsuro Ishibashi, Katsuo Sueishi<br />
834<br />
Highly Efficient and Tumor-Selective <strong>Gene</strong> Delivery in<br />
Metastatic Colon Cancer Models Using a Replication-<br />
Competent Retrovirus Vector<br />
Kei Hiraoka, Takahiro Kimura, Christopher Logg, Satoshi<br />
Kondo, Noriyuki Kasahara<br />
835<br />
<strong>Gene</strong> <strong>Therapy</strong> for Arthritis: Long-Term Expression in a<br />
Sub-Population <strong>of</strong> Synovial Fibroblasts<br />
Elvire Gouze, Jean-Noel Gouze, Glyn D. Palmer, Carmencita<br />
Pilapil, Christopher H. Evans, Steven C. Ghivizzani<br />
836<br />
Suitability <strong>of</strong> Anti-Retroviral <strong>Gene</strong>s for <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong><br />
AIDS<br />
Matthias Schweizer, Sabine Fengler, Silke Schuele, Sylvia<br />
Raupp, Carsten Muenk, Dorothee M. von Laer, Klaus Cichutek<br />
837<br />
Prolonged <strong>Gene</strong> Expression in Murine Salivary Glands<br />
Following FIV-Based Lentiviral Vector Transduction<br />
Ela Shai, Reba Condiotti, Michael A. Curran, Garry P. Nolan,<br />
Eithan Galun<br />
838<br />
Construction and Use <strong>of</strong> Retroviral Vectors Encoding the<br />
Toxic <strong>Gene</strong> Barnase<br />
Sumit Agarwal, Bryan Nikolai, Tomoyuki Yamaguchi, Nikunj<br />
V. Somia
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